Product Name

  • Name

    4-Fluoro-3-nitrophenyl azide

  • EINECS 248-878-6
  • CAS No. 28166-06-5
  • Article Data9
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 54-56 ºC
  • Formula C6H3FN4O2
  • Boiling Point
  • Molecular Weight 182.114
  • Flash Point 113 °C
  • Transport Information
  • Appearance
  • Safety 36/37/39-45
  • Risk Codes 5-11-23/24/25
  • Molecular Structure Molecular Structure of 28166-06-5 (4-Fluoro-3-nitrophenyl azide)
  • Hazard Symbols ToxicT,FlammableF,IrritantXi
  • Synonyms 1-Fluoro-2-nitro-4-azidobenzene;2-Nitro-4-azidofluorobenzene;4-Azido-1-fluoro-2-nitrobenzene;4-Azido-2-nitrofluorobenzene;4-Azido-2-nitrophenyl fluoride;NSC 266503;
  • PSA 95.57000
  • LogP 2.65166

Synthetic route

4-Fluoro-3-nitroaniline
364-76-1

4-Fluoro-3-nitroaniline

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

Conditions
ConditionsYield
Stage #1: 4-Fluoro-3-nitroaniline With hydrogenchloride; sodium nitrite In water at 70℃;
Stage #2: With sodium azide In water at 70℃;		98%
With sodium azide; tert.-butylnitrite In tert-butyl alcohol at 20℃; for 1h;92%
Stage #1: 4-Fluoro-3-nitroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.25h;
Stage #2: With sodium azide In water at 20℃; for 0.5h;		75%
Stage #1: 4-Fluoro-3-nitroaniline With hydrogenchloride; sodium nitrite In water at 5℃; for 0.5h; Cooling with ice;
Stage #2: With sodium azide In water at 0℃;		73%
(i) aq. H2SO4, NaNO2, (ii) aq. NaN3; Multistep reaction;
sodium azide

sodium azide

4-Fluoro-3-nitroaniline
364-76-1

4-Fluoro-3-nitroaniline

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

Conditions
ConditionsYield
Stage #1: 4-Fluoro-3-nitroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.166667h;
Stage #2: sodium azide In water at 0℃; for 4.25h;
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(prop-2-ynylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-98-3

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(prop-2-ynylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-(2-chloro-6-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-99-4

(1R,2R,3S,4R,5S)-4-(2-chloro-6-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In water; tert-butyl alcohol at 20℃;96%
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;96%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(nona-1,8-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309943-74-5

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(nona-1,8-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(7-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hept-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309943-77-8

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(7-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hept-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

Conditions
ConditionsYield
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;96%
thiobenzoic acid
98-91-9

thiobenzoic acid

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

N-(4-fluoro-3-nitrophenyl)-benzylamide
228425-41-0

N-(4-fluoro-3-nitrophenyl)-benzylamide

Conditions
ConditionsYield
With 2,6-dimethylpyridine In methanol at 25℃; for 15h;95%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(octa-1,7-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-87-0

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(octa-1,7-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(6-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hex-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-90-5

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(6-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hex-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

Conditions
ConditionsYield
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;95%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

thioacetic acid
507-09-5

thioacetic acid

N-(4-fluoro-3-nitrophenyl)acetamide
351-32-6

N-(4-fluoro-3-nitrophenyl)acetamide

Conditions
ConditionsYield
With 2,6-dimethylpyridine In methanol at 25℃; for 15h;94%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-chlorobenzylamino)-2-(1,7-octadiynyl)-9H-purin-9-yl]-2',3'-dihydroxybicyclo[3.1.0]hexane-1'-carboxylic acid N-methylamide
1213770-15-0

(1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-chlorobenzylamino)-2-(1,7-octadiynyl)-9H-purin-9-yl]-2',3'-dihydroxybicyclo[3.1.0]hexane-1'-carboxylic acid N-methylamide

MRS5223
1217299-58-5

MRS5223

Conditions
ConditionsYield
With copper(II) sulphate hydrate; sodium L-ascorbate In tetrahydrofuran; water at 20℃; regioselective reaction;94%
With copper(ll) sulfate pentahydrate; sodium L-ascorbate In tetrahydrofuran; water at 20℃;94%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(octa-1,7-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309944-05-5

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(octa-1,7-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(6-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hex-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309943-76-7

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(6-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hex-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

Conditions
ConditionsYield
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;94%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1S,2R,3S,4R,5S)-4-(2-chloro-6-(prop-2-ynylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
1309943-94-9

(1S,2R,3S,4R,5S)-4-(2-chloro-6-(prop-2-ynylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-(2-chloro-6-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
1309943-95-0

(1S,2R,3S,4R,5S)-4-(2-chloro-6-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In water; tert-butyl alcohol at 20℃;92%
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;92%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

17α-aminomethyl-3,3-(dimethoxy)-5α-androstan-17β-ol
300350-92-9

17α-aminomethyl-3,3-(dimethoxy)-5α-androstan-17β-ol

17α-[(N-4-azido-2-nitrophenyl)aminomethyl]-3,3-dimethoxy-5α-androstan-17β-ol
300351-06-8

17α-[(N-4-azido-2-nitrophenyl)aminomethyl]-3,3-dimethoxy-5α-androstan-17β-ol

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; diethyl ether; ethanol91%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(hepta-1,6-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-86-9

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(hepta-1,6-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-89-2

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃;91%
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;91%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(nona-1,8-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-88-1

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(nona-1,8-diynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(7-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hept-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
1309943-91-6

(1R,2R,3S,4R,5S)-4-(2-chloro-6-(3-(7-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)hept-1-ynyl)benzylamino)-9H-purin-9-yl)bicyclo[3.1.0]hexane-2,3-diol

Conditions
ConditionsYield
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;91%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(hepta-1,6-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309944-03-3

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(hepta-1,6-diynyl)phenylmethylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1309943-75-6

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(3-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)benzylamino)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃;90%
With sodium ascorbate; copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine In dichloromethane; water; tert-butyl alcohol at 20℃; Inert atmosphere;90%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

ethylenediamine
107-15-3

ethylenediamine

4-(2-aminoethyl)amino-3-nitro-phenylazide (napa)
64309-07-5

4-(2-aminoethyl)amino-3-nitro-phenylazide (napa)

Conditions
ConditionsYield
In dichloromethane for 24h; Ambient temperature;89%
In dichloromethane for 0.5h; Ambient temperature; in the dark;70%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-chlorobenzylamino)-2-(1,6-heptadiynyl)-9H-purin-9-yl]-2',3'-dihydroxybicyclo[3.1.0]hexane-1'-carboxylic acid N-methylamide
1217299-55-2

(1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-chlorobenzylamino)-2-(1,6-heptadiynyl)-9H-purin-9-yl]-2',3'-dihydroxybicyclo[3.1.0]hexane-1'-carboxylic acid N-methylamide

(1S,2R,3S,4R,5S)-4-(6-(3-chlorobenzylamino)-2-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)-9H-purin-9-yl)-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide
1217299-57-4

(1S,2R,3S,4R,5S)-4-(6-(3-chlorobenzylamino)-2-(5-(1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)pent-1-ynyl)-9H-purin-9-yl)-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid N-methylamide

Conditions
ConditionsYield
With copper(II) sulphate hydrate; sodium L-ascorbate In tetrahydrofuran; water at 20℃; regioselective reaction;89%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

C16H14O7
1285718-33-3

C16H14O7

C22H17FN4O9
1285718-37-7

C22H17FN4O9

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; sodium L-ascorbate In dichloromethane; water at 20℃;87%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

6-methyl-2-oxo-1-(prop-2-yn-1-yl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile
1582270-75-4

6-methyl-2-oxo-1-(prop-2-yn-1-yl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile

1-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile
1582270-94-7

1-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile

Conditions
ConditionsYield
Stage #1: 6-methyl-2-oxo-1-(prop-2-yn-1-yl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile With copper(l) iodide In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 4-fluoro-3-nitrophenylazide In tetrahydrofuran for 12h;		86%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

6-phenyl-2-(prop-2-yn-1-yloxy)-4-(trifluoromethyl)nicotinonitrile
1336913-39-3

6-phenyl-2-(prop-2-yn-1-yloxy)-4-(trifluoromethyl)nicotinonitrile

2-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile
1582270-81-2

2-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
Stage #1: 6-phenyl-2-(prop-2-yn-1-yloxy)-4-(trifluoromethyl)nicotinonitrile With copper(l) iodide In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 4-fluoro-3-nitrophenylazide In tetrahydrofuran for 12h;		85%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

ethyl 2-(prop-2-ynyloxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylate
1591994-08-9

ethyl 2-(prop-2-ynyloxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylate

ethyl 2-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazole-4-yl)methoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylate
1591994-28-3

ethyl 2-((1-(4-fluoro-3-nitrophenyl)-1H-1,2,3-triazole-4-yl)methoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylate

Conditions
ConditionsYield
Stage #1: ethyl 2-(prop-2-ynyloxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylate With copper(l) iodide In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: 4-fluoro-3-nitrophenylazide In tetrahydrofuran at 20℃;		82%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

12-Aminododecanoic acid
693-57-2

12-Aminododecanoic acid

C18H27N5O4
58775-40-9

C18H27N5O4

Conditions
ConditionsYield
In methanol; N,N-dimethyl-formamide at 80℃;80%
1,6-Hexanediamine
124-09-4

1,6-Hexanediamine

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

N'-(4-azido-2-nitrophenyl)hexane-1,6-diamine
64309-09-7

N'-(4-azido-2-nitrophenyl)hexane-1,6-diamine

Conditions
ConditionsYield
In methanol at 20℃; for 12h; Inert atmosphere;80%
Geraniol
106-24-1

Geraniol

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

p-azido-o-nitrophenyl geranyl ether
106929-46-8

p-azido-o-nitrophenyl geranyl ether

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 14h; Ambient temperature;76%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

diethylamine
109-89-7

diethylamine

4-(N,N-diethylamino)-3-nitrophenylazide

4-(N,N-diethylamino)-3-nitrophenylazide

Conditions
ConditionsYield
In acetonitrile at 40℃; for 3h;67%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

(8R,9S,13S,14S,16S)-16-(4-Amino-but-2-ynyl)-3-(tert-butyl-dimethyl-silanyloxy)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one
234765-89-0

(8R,9S,13S,14S,16S)-16-(4-Amino-but-2-ynyl)-3-(tert-butyl-dimethyl-silanyloxy)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

16α-(4-(4-azido-2-nitrophenylamino)-2-butynyl)estra-1,3,5(10)-triene-3,17β-diol

16α-(4-(4-azido-2-nitrophenylamino)-2-butynyl)estra-1,3,5(10)-triene-3,17β-diol

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 44h; Ambient temperature;59.9%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

histamine dichloride
56-92-8

histamine dichloride

water ethanol
180330-54-5

water ethanol

sodium carbonate
497-19-8

sodium carbonate

4(5)-[2-(4-azido-2-nitroanilino)ethyl]imidazole hydrochloride
79412-26-3

4(5)-[2-(4-azido-2-nitroanilino)ethyl]imidazole hydrochloride

Conditions
ConditionsYield
With hydrogenchloride58%
...Expand
6-amino-1-hexanol
4048-33-3

6-amino-1-hexanol

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

6-(4-Azido-2-nitro-phenylamino)-hexan-1-ol

6-(4-Azido-2-nitro-phenylamino)-hexan-1-ol

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane at 20℃; for 2h;55%
In 1,4-dioxane
Stage #1: 6-amino-1-hexanol; 4-fluoro-3-nitrophenylazide In 1,4-dioxane at 20℃; for 0.333333h;
Stage #2: With triethylamine In 1,4-dioxane at 20 - 55℃; for 16h;		16 g
4-pyrrol-1-yl-butylamine
98492-69-4

4-pyrrol-1-yl-butylamine

4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

C14H20N6O2

C14H20N6O2

Conditions
ConditionsYield
In tetrahydrofuran for 0.5h;54%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

3,3-(dimethoxy)-17α-aminopropyl-17β-hydroxy-5α-androstan-3-one
300350-96-3

3,3-(dimethoxy)-17α-aminopropyl-17β-hydroxy-5α-androstan-3-one

17α-[(N-4-azido-2-nitrophenyl)aminopropyl]-3,3-dimethoxy-5α-androstan-17β-ol
300351-12-6

17α-[(N-4-azido-2-nitrophenyl)aminopropyl]-3,3-dimethoxy-5α-androstan-17β-ol

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; diethyl ether; ethanol47%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

N-(2-aminoethyl)-N'-cyano-N''-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>guanidine
140872-99-7

N-(2-aminoethyl)-N'-cyano-N''-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>guanidine

C25H32N10O3
140873-16-1

C25H32N10O3

Conditions
ConditionsYield
With sodium carbonate In ethanol for 15h; Heating;45%
4-fluoro-3-nitrophenylazide
28166-06-5

4-fluoro-3-nitrophenylazide

C20H32N6O
140900-93-2

C20H32N6O

C26H34N10O3
140873-20-7

C26H34N10O3

Conditions
ConditionsYield
With sodium carbonate In ethanol for 15h; Heating;44%

4-Fluoro-3-nitrophenyl azide Specification

The Benzene,4-azido-1-fluoro-2-nitro-, with the CAS registry number 2817-13-2, is also known as 2-Nitro-4-azidofluorobenzene. Its EINECS number is 248-878-6. This chemical's molecular formula is C6H3FN4O2 and formula weight is 182.11. What's more, its IUPAC name is 4-azido-1-fluoro-2-nitrobenzene. Its classification code is Mutation data. Its storage temperature is 2-8°C.It is used as an affinity label for insulin to give mono-azide-nitrophenyl-insulin derivatives. It is highly flammable. Once heated, it may cause an explosion. It is toxic by inhalation, in contact with skin and if swallowed. When using it, you should wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

Physical properties about 4-Fluoro-3-nitrophenyl azide are:
(1)ACD/LogP:2.441; (2) # of Rule of 5 Violations:0; (3)ACD/LogD (pH 5.5):2.44; (4)ACD/LogD (pH 7.4):2.44; (5)ACD/BCF (pH 5.5):42.18; (6)ACD/BCF (pH 7.4):42.18; (7)ACD/KOC (pH 5.5): 506.86; (8)ACD/KOC (pH 7.4): 506.86; (9)#H bond acceptors: 6; (10)#H bond donors:0; (11)#Freely Rotating Bonds:2.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC(=C(C=C1N=[N+]=[N-])[N+](=O)[O-])F
(2)InChI: InChI=1S/C6H3FN4O2/c7-5-2-1-4(9-10-8)3-6(5)11(12)13/h1-3H
(3)InChIKey: VCTBSHQJICJJFV-UHFFFAOYSA-N

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View