7-Aminoheptanoic acid supplier

Name
7-Aminoheptanoic acid
EINECS 213-197-5
CAS No. 929-17-9
Article Data33
CAS DataBase
Density 1.019 g/cm³
Solubility Soluble in water
Melting Point 192-195 °C(lit.)
Formula C₇H₁₅NO₂
Boiling Point 270.6 °C at 760 mmHg
Molecular Weight 145.202
Flash Point 117.5 °C
Transport Information
Appearance
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 7-Aminohepentanoic acid;Amino-enanthylic acid;omega-Aminoenantic acid;Kyselina 7-aminoenanthova [Czech];Aminoenanthic acid;4-04-00-02791 (Beilstein Handbook Reference);omega-Aminoheptanoic acid;
PSA 63.32000
LogP 1.68050

Synthetic route

: 673-66-5
7-amino-heptanoic acid lactam

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride	100%
Stage #1: 7-amino-heptanoic acid lactam With water; barium(II) hydroxide at 110℃; for 6h; Stage #2: With carbon dioxide for 0.333333h;	93%
With sulfuric acid; water at 94℃; Rate constant; Mechanism; effective rate constants for hydrolysis at different temperatures; further temperatures;

: 30515-28-7
7-bromoheptanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With ammonium hydroxide In water at 20℃;	99%

: 673-66-5
7-amino-heptanoic acid lactam

: barium(II) hydroxide

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Stage #1: 7-amino-heptanoic acid lactam; barium(II) hydroxide With water at 110℃; for 6h; Stage #2: With carbon dioxide In water for 0.333333h; Cooling with ice;	93%

: 110346-63-9
7-nitroheptanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With ammonium formate; palladium on activated charcoal In methanol at 80℃; for 0.5h;	87%

: 23181-80-8
7-aminoheptanenitrile

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With barium dihydroxide
With sodium hydroxide

: 821-57-8
7-chloroheptanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With ammonia

: 7790-12-7
7-amino-heptanoic acid isopropyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

: 855897-82-4
7-acetylamino-heptanoic acid methyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With sodium hydroxide

: 855898-67-8
7-methoxycarbonylamino-heptanoic acid methyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride
With barium dihydroxide

: 1149-15-1
7-(benzoylamino)heptanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

: 859201-09-5
(5-benzoylamino-pentyl)-malonic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride
Multi-step reaction with 2 steps 1: 145 - 150 °C 2: concentrated hydrochloric acid View Scheme

: 7-{[1-(2-Hydroxy-phenyl)-meth-(E)-ylidene]-amino}-heptanoic acid

A: 90-02-8
salicylaldehyde

B: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With phosphate buffer In methanol Rate constant; var. pH;

: 673-66-5
7-amino-heptanoic acid lactam

: 7647-01-0
hydrogenchloride

: 929-17-9
7-aminoheptanoic acid

7-benzamino-heptanoic acid: 7-benzamino-heptanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

<ε-benzamino-n-pentyl>-malonic acid diethyl ester: <ε-benzamino-n-pentyl>-malonic acid diethyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

<ε-phthalimido-n-pentyl>-malonic acid diethyl ester: <ε-phthalimido-n-pentyl>-malonic acid diethyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogen bromide

<5-benzamino-pentyl>-malonic acid: <5-benzamino-pentyl>-malonic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

: 996-82-7, 34727-00-9, 73177-21-6
sodium diethylmalonate

N-benzoyl-ε-iodo-n-pentylamine: N-benzoyl-ε-iodo-n-pentylamine

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With ethanol man erhitzt den erhaltenen Ester mit konz. Salzsaeure im geschlossenen Rohr auf 160-170grad;

pimelic acid mononitrile of potassium salt: pimelic acid mononitrile of potassium salt

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With ammonia; nickel at 100℃; under 73550.8 Torr; Hydrogenation;

suberone oxime: suberone oxime

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With sulfuric acid entsteht das Anhydrid; man spaltet das durch Erhitzen mit Salzsaeure auf;

: 7647-01-0
hydrogenchloride

: 859931-68-3
(5-benzoylamino-pentyl)-malonic acid diethyl ester

: 929-17-9
7-aminoheptanoic acid

: 7647-01-0
hydrogenchloride

: 859201-09-5
(5-benzoylamino-pentyl)-malonic acid

: 929-17-9
7-aminoheptanoic acid

: 646-20-8
pimelonitrile

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: cobalt; liquid NH3 / 120 °C / 128714 Torr / Hydrogenation 2: aqueous Ba(OH)2 View Scheme

: 17592-25-5
methyl 6-cyanohexanoate

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: platinum / Hydrogenation 2: aq. NaOH solution View Scheme

: 98553-02-7
6-carbamoyl-hexanoic acid methyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: phosphorus (V)-chloride 2: platinum / Hydrogenation 3: aq. NaOH solution View Scheme

: 93432-24-7
N-(5-iodo-pentyl)-benzamide

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: Irradiation 2: aqueous-alcoholic NaOH-solution 3: 145 - 150 °C 4: concentrated hydrochloric acid View Scheme
Multi-step reaction with 3 steps 1: Irradiation 2: aqueous-alcoholic NaOH-solution 3: concentrated hydrochloric acid View Scheme

: 859931-68-3
(5-benzoylamino-pentyl)-malonic acid diethyl ester

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: aqueous-alcoholic NaOH-solution 2: 145 - 150 °C 3: concentrated hydrochloric acid View Scheme
Multi-step reaction with 2 steps 1: aqueous-alcoholic NaOH-solution 2: concentrated hydrochloric acid View Scheme

: 502-42-1
cycloheptanone

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: hydroxylamine-O-sulfonic acid; water; formic acid / 5.05 h / Reflux 1.2: 20 °C / pH 7 / Cooling with ice 2.1: water / 6 h / 110 °C 2.2: 0.33 h / Cooling with ice View Scheme
Multi-step reaction with 2 steps 1.1: hydroxylamine-O-sulfonic acid; formic acid / 5.05 h / Reflux; Inert atmosphere 2.1: barium(II) hydroxide; water / 6 h / 110 °C 2.2: 0.33 h View Scheme

: 35923-65-0
6-formyl hexanoic acid

: 929-17-9
7-aminoheptanoic acid

Conditions

Conditions	Yield
With L-alanin; pyridoxal 5'-phosphate; Chromobacterium violaceum ω-transaminase; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid at 25℃; for 4h; pH=7.5; Catalytic behavior; Reagent/catalyst; Enzymatic reaction;

: 67-56-1
methanol

: 929-17-9
7-aminoheptanoic acid

: 17994-94-4
methyl 7-aminoheptanoate hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at 20℃; for 5h;	100%
With thionyl chloride at -10 - 20℃;	100%
With thionyl chloride at -10 - 20℃;	100%

: 929-17-9
7-aminoheptanoic acid

: 135920-28-4
5-azido-1-pentylacetate

Conditions

Conditions	Yield
With triflic azide; potassium carbonate; copper(II) sulfate In methanol; dichloromethane; water	99%
With copper(ll) sulfate pentahydrate; triflic azide; potassium carbonate In methanol; water at 21℃;	10.7%

: 1131147-67-5
(1H-benzo[d][1,2,3]triazol-1-yl)(3,3-diphenyl-3H-benzo[f]chromen-8-yl)methanone

: 929-17-9
7-aminoheptanoic acid

: 1131147-88-0
7-(3,3-diphenyl-3H-benzo[f]chromene-8-carboxamido)heptanoic acid

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran; water at 20℃; for 4h;	97%

: 64-17-5
ethanol

: 929-17-9
7-aminoheptanoic acid

: 29840-65-1
7-aminoheptanoic acid ethyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride for 20h; Ambient temperature;	95%
With thionyl chloride for 12h;

: 24424-99-5
di-tert-butyl dicarbonate

: 929-17-9
7-aminoheptanoic acid

: 60142-89-4
7-[(tert-butoxycarbonyl)amino]heptanoic acid

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane; water at 0 - 20℃;	94%
With sodium hydroxide In tert-butyl alcohol at 20℃;	82%
With sodium carbonate In 1,4-dioxane at 50℃; for 12h;	52%

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 929-17-9
7-aminoheptanoic acid

: 7-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane at 20℃;	93%
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃; for 18h;	89%
With sodium carbonate In 1,4-dioxane; water

: 107-18-6
allyl alcohol

: 929-17-9
7-aminoheptanoic acid

: 210630-71-0
allyl 7-aminoheptanoic ester

Conditions

Conditions	Yield
With thionyl chloride for 24h; Ambient temperature;	90%

: 2937-50-0
Allyl chloroformate

: 929-17-9
7-aminoheptanoic acid

: 400707-99-5
7-allyloxycarbonylamino-heptanoic acid

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane for 1h;	90%

: 111-70-6
n-heptan1ol

: 104-15-4
toluene-4-sulfonic acid

: 929-17-9
7-aminoheptanoic acid

: 7-(heptyloxy)-7-oxoheptylammonium p-toluenesulfonate

Conditions

Conditions	Yield
In toluene at 110℃; for 8h; Schlenk technique; Inert atmosphere;	90%

...Expand

: 65-85-0
benzoic acid

: 929-17-9
7-aminoheptanoic acid

: 1149-15-1
7-(benzoylamino)heptanoic acid

Conditions

Conditions	Yield
Stage #1: benzoic acid With pyridine; pentafluorophenyl trifloroacetate In N,N-dimethyl-formamide at 20℃; for 3h; Inert atmosphere; Stage #2: 7-aminoheptanoic acid With sodium hydrogencarbonate In water; N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;	89%

: 85-44-9
phthalic anhydride

: 929-17-9
7-aminoheptanoic acid

: 1154-46-7
7-(1,3-dioxoisoindolin-2-yl)heptanoic acid

Conditions

Conditions	Yield
at 180℃; for 2h;	89%
With triethylamine In toluene for 12h; Heating;	76%

: 501-53-1
benzyl chloroformate

: 929-17-9
7-aminoheptanoic acid

: 23434-37-9
7-(((benzyloxy)carbonyl)amino)heptanoic acid

Conditions

Conditions	Yield
With sodium hydroxide In water at 0 - 20℃; for 0.5h;	88%
With sodium hydroxide stirred overnight;
In sodium hydroxide	7.8g (28 mmol; 81 %)

: 58632-95-4
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

: 929-17-9
7-aminoheptanoic acid

: 60142-89-4
7-[(tert-butoxycarbonyl)amino]heptanoic acid

Conditions

Conditions	Yield
With triethylamine In 1,4-dioxane; water for 3h;	88%

: C9H2O5Re

: 929-17-9
7-aminoheptanoic acid

: tricarbonyl(8-{[(η5-cyclopentadienyl)carbonyl]amino}octanoic acid)rhenium

Conditions

Conditions	Yield
With pentafluorophenyl trifloroacetate; sodium hydrogencarbonate In water; N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;	86%

: 107-18-6
allyl alcohol

: 929-17-9
7-aminoheptanoic acid

: allyl 7-aminoheptanoate hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at -10 - 20℃; for 16h;	85.1%

: 107-18-6
allyl alcohol

: 929-17-9
7-aminoheptanoic acid

: C11H19NO4

Conditions

Conditions	Yield
In thionyl chloride at -10 - 20℃; for 16h;	85.1%

: 108-31-6
maleic anhydride

: 929-17-9
7-aminoheptanoic acid

: 7-((Z)-3-Carboxy-acryloylamino)-heptanoic acid

Conditions

Conditions	Yield
With acetic acid Ambient temperature;	84%

: 23810-52-8
m-carborane-1,7-dicarboxylic acid dichloride

: 929-17-9
7-aminoheptanoic acid

: 186822-47-9
C2B10H10(CONH(CH2)6COOH)2

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydroxide In water byproducts: NaCl; stirring (20-30°C, 2-3 h), aq. HCl addn.; washing (water), drying (vac.); elem. anal.;	84%

: 929-17-9
7-aminoheptanoic acid

: 512-04-9
diosgenin

: (22β,25R)-spirost-5-en-3β-yl n-octanoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 30 - 35℃; Inert atmosphere;	84%

: 22509-74-6
N-ethoxycarbonylphthalimide

: 929-17-9
7-aminoheptanoic acid

: 1154-46-7
7-(1,3-dioxoisoindolin-2-yl)heptanoic acid

Conditions

Conditions	Yield
With sodium carbonate In water for 6h;	83%

: (2E)-cyclooct-2’-en-1’-yl 4-nitrophenyl carbonate

: 929-17-9
7-aminoheptanoic acid

: axial-(E)-7-(((cyclooct-2-en-1-yloxy)carbonyl)amino)heptanoic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 20h;	82%

: 929-17-9
7-aminoheptanoic acid

: 673-66-5
7-amino-heptanoic acid lactam

Conditions

Conditions	Yield
With di(n-butyl)tin oxide In toluene for 16h; Dean-Stark; Reflux;	81%
With di(n-butyl)tin oxide In 1,3,5-trimethyl-benzene for 6h; Heating;	8%
at 180 - 190℃; im Vakuum;
Multi-step reaction with 3 steps 1: 99 percent / N3Tf; CuSO4; K2CO3 / CH2Cl2; methanol; H2O 2: 96 percent / N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 0 °C 3: 59 percent / 1,4-diazabicyclo[2.2.2]octane / tetrahydrofuran; H2O / 70 °C View Scheme

: 25508-20-7
N,N'-bis(benzyloxycarbonyl)-S-methylisothiourea

: 929-17-9
7-aminoheptanoic acid

: 189245-00-9
N,N′-(bis-Cbz-guanidino)heptanoic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran at 65℃; for 6h; Substitution;	81%

: (S)-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid

: 929-17-9
7-aminoheptanoic acid

: C26H30ClN5O3S

Conditions

Conditions	Yield
With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 23℃; for 16.5h; Cooling with ice;	81%

: 929-17-9
7-aminoheptanoic acid

: 5602-19-7
6-cyanohexanaoic acid

Conditions

Conditions	Yield
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; free radical; trichloroisocyanuric acid In dichloromethane at 10℃; for 4.5h;	80%

: 5453-04-3, 866541-93-7, 1189561-66-7
(±)-gossypol acetic acid

: 929-17-9
7-aminoheptanoic acid

: C44H56N2O10

Conditions

Conditions	Yield
In ethanol	79%
In ethanol at 20℃;	75%

7-Aminoheptanoic acid Chemical Properties

The molecular formula of 7-Aminoheptanoic acid(929-17-9) is C₇H₁₅NO₂ and its formula weight is 145.2.
7-Aminoheptanoic acid(929-17-9) has a melting point of 192-195 °C(lit.).
The chemical synonyms of 7-Aminoheptanoic acid(929-17-9) are NH2-(CH2)6-COOH;OMEGA-AMINOENANTHIC ACID;OMEGA-AMINOHEPTANOIC ACID;O-AMINO HEPTANOIC ACID;7-AMINOENANTHIC ACID;7-AMINOOENANTHIC ACID;7-AMINOHEPTANOIC ACID;H-7-AHP-OH
The molecular structure of 7-Aminoheptanoic acid(929-17-9):

7-Aminoheptanoic acid Safety Profile

Safety Statements 22-24/25
WGK Germany 2
RTECS MJ1770000

Product Name

7-Aminoheptanoic acid

Synthetic route

7-Aminoheptanoic acid Chemical Properties

7-Aminoheptanoic acid Safety Profile

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