Amino tris(methylene phosphonic acid) supplier

Name
Amino tris(methylene phosphonic acid)
EINECS 229-146-5
CAS No. 6419-19-8
Article Data15
CAS DataBase
Density 2.094 g/cm³
Solubility 500g/L at 20℃
Melting Point ~215 °C (dec.)
Formula C₃H₁₂NO₉P₃
Boiling Point 746.2 °C at 760 mmHg
Molecular Weight 299.051
Flash Point 405.1 °C
Transport Information
Appearance colourless liquid
Safety 26-45-36/37/39-25
Risk Codes 36-34
Molecular Structure
Hazard Symbols Xi,C
Synonyms Phosphonicacid, [nitrilotris(methylene)]tri- (6CI,7CI,8CI);Phosphonic acid,[nitrilotris(methylene)]tris- (9CI);1,1,1-Nitrilotris(methylphosphonic acid);ATMP (phosphonic acid);Aminotri(methylenephosphonic acid);Briquest 301;Briquest 301-50A;Chelest PH320;Cublen AP 1;Dequest 2000;Dequest 2001;Ferrofos 509;Mayoquest 1320;NTP-A;Nitrilo-N,N,N-trimethylenephosphonic acid;Nitrilotrimethanephosphonic acid;Sequion 20H45;Sequion OA;Unihib 305;WSI 3300;[Nitrilotris(methylene)]triphosphonic acid;a,a',a''-Aminotris(methylphosphonicacid);
PSA 205.26000
LogP -1.30600

Synthetic route

: 50-00-0
formaldehyd

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

Conditions

Conditions	Yield
With phosphoric acid; ammonia In water at 126 - 136℃; for 4h; Product distribution / selectivity;	72%
With hydrogenchloride; phosphonic Acid; ammonium chloride
With ammonium chloride; phosphorus trichloride

: 120060-75-5
N-(triphenylmethyl)methanimine

: 108-24-7
acetic anhydride

A: 1066-51-9
Aminomethylphosphonic acid

B: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

C: 17261-34-6
(iminobismethylene)bisphosphonic acid

Conditions

Conditions	Yield
Stage #1: acetic anhydride With phosphonic Acid at 0 - 20℃; Stage #2: N-(triphenylmethyl)methanimine at 0℃; Stage #3: With hydrogenchloride; water for 8h; Reflux;	A 54% B 9 %Spectr. C 13 %Spectr.

...Expand

: 6806-71-9
P,P',P''-azanetriyltrimethyl-tris-phosphonic acid hexaethyl ester

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

Conditions

Conditions	Yield
With hydrogenchloride at 130 - 140℃;
With hydrogenchloride Heating;

: 50-00-0
formaldehyd

A: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

B: 2617-47-2
hydroxymethylphosphonic acid

Conditions

Conditions	Yield
With ammonium chloride; phosphorus trichloride Mechanism;

: 3852-14-0
N,N-methylenediacetamide

A: 1066-51-9
Aminomethylphosphonic acid

B: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid; phosphorus trichloride 1) 1h, reflux 2) 12h, reflux; Yield given. Multistep reaction. Yields of byproduct given;

: 50-00-0
formaldehyd

: 100-97-0
hexamethylenetetramine

A: 1066-51-9
Aminomethylphosphonic acid

B: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

C: 17261-34-6
(iminobismethylene)bisphosphonic acid

D: 5995-25-5
N-methyliminobis(methylphosphonic acid)

Conditions

Conditions	Yield
With phosphoric acid Mechanism; Product distribution;

...Expand

: 50-00-0
formaldehyd

A: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

B: 5995-25-5
N-methyliminobis(methylphosphonic acid)

Conditions

Conditions	Yield
With hydrogenchloride; phosphorus(III) oxide; water; ammonium chloride at 100 - 110℃; Product distribution / selectivity; Inert atmosphere;

: 139-13-9
nitrilotriacetic acid

A: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

B: 15834-10-3
aminotrismethylenephosphonic acid N-oxide

Conditions

Conditions	Yield
With phosphorus(III) oxide; trifluorormethanesulfonic acid at 45 - 50℃; for 3h;	A 8.5 %Spectr. B 9.5 %Spectr.

: 139-13-9
nitrilotriacetic acid

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

Conditions

Conditions	Yield
With phosphorus(III) oxide; methanesulfonic acid at 75℃; for 0.5h; Concentration; Reagent/catalyst; Time; Temperature;	95.6 %Spectr.

: 50-00-0
formaldehyd

: ammonium bicarbonate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

Conditions

Conditions	Yield
Stage #1: ammonium bicarbonate With hydrogenchloride; phosphorous acid at 50℃; for 4.5h; Large scale; Stage #2: formaldehyd at 95 - 110℃; for 21h; Temperature; Large scale;

: 108-78-1
2,4,6-triamino-s-triazine

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: bismelaminium aminotrimethanephosphonate

Conditions

Conditions	Yield
In water Heating;	94%

: yttrium(lll) nitrate hexahydrate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 7732-18-5
water

: nitrilotris(methylenephosphonato)yttrium dihydrate

Conditions

Conditions	Yield
at 70 - 90℃; for 1h;	94%

...Expand

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 7732-18-5
water

: samarium(III) nitrate

: [SmH3{N(CH2PO3)3}] · 1.5H2O

Conditions

Conditions	Yield
With nitric acid at 20℃; pH=2.5;	91%

...Expand

: aluminum dihydrogen phosphate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: aluminum trihydrogenaminotrimethanephosphonate

Conditions

Conditions	Yield
	90%

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 57-13-6
urea

: nitrilotris(methylene)triphosphonic acid amide ammonium salt

Conditions

Conditions	Yield
at 100 - 200℃; for 12h;	83%

: cobalt(II) chloride hexahydrate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: [Co(HN(CH2PO3H)3)(H2O)3]n

Conditions

Conditions	Yield
With sodium hydroxide In water at 150℃; for 120h; pH=3; Autoclave;	83%

: 110-86-1
pyridine

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 7732-18-5
water

: 6046-93-1
copper(II) acetate monohydrate

: 332917-97-2
(pyridinium)[Cu(II)(nitrilotrimethylenetrisphosphonate)(H2O)]

Conditions

Conditions	Yield
In pyridine; water a soln. of ligand in water-pyridine was added to a soln. of Cu salt in pyridine; acetone was added, ppt. was formed for 24 h, ppt. was filtered off, washed with acetone, dried in vac., ppt. was dissolved in water and pptd. byslow diffusion of acetone through the soln.; elem. anal.;	80%

...Expand

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 17261-34-6
(iminobismethylene)bisphosphonic acid

Conditions

Conditions	Yield
With nitric acid In water Heating;	78%
With sulfuric acid In water at 140℃; for 25h;

: ammonium molibdate

: copper(II) chloride hexahydrate

: sodium tellurite

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 7732-18-5
water

: 29H(1+)*31H2O*19H3N*7Na(1+)*C18H48Cu6Mo36N6O186P18Te6(36-)

Conditions

Conditions	Yield
With sodium hydroxide In aq. acetate buffer at 80℃; for 2h; pH=5 - 5.3;	76.5%

...Expand

: gadolinium(III) nitrate hexahydrate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: 7732-18-5
water

: 1310-73-2
sodium hydroxide

: 2C3H6NO9P3(6-)*8Na(1+)*Gd(3+)*26H2O*H(1+)

Conditions

Conditions	Yield
Stage #1: gadolinium(III) nitrate hexahydrate With sodium hydroxide Stage #2: nitrilo-tris(methylenephosphonic acid); water; sodium hydroxide pH=8.5;	75%

...Expand

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: nitrilotris(methylenephosphonato)yttrium dihydrate

: 7732-18-5
water

: potassium hydroxide

: octapotassium monohydro-bis-nitrilotris(methylenephosphonato)yttriate pentadecahydrate

Conditions

Conditions	Yield
at 60 - 80℃; for 1h; pH=7.8;	74%

...Expand

: magnesium(II) chloride hexahydrate

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: C3H10NO9P3(2-)*Mg(2+)*3H2O

Conditions

Conditions	Yield
With sodium hydroxide In water at 120℃; for 149h; pH=2; Autoclave; High pressure;	73%

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: copper hydroxycarbonate

: 7732-18-5
water

: 1310-73-2
sodium hydroxide

: octa-sodium bis(μ-[nitrilotris(methylene)]tris(phosphonato))-di-copper(II) nonadecahydrate

Conditions

Conditions	Yield
at 40 - 50℃;	73%

...Expand

: 6419-19-8
nitrilo-tris(methylenephosphonic acid)

: calcium amino-tris-(methylene phosphonate) tetrahemihydrate

Conditions

Conditions	Yield
Stage #1: nitrilo-tris(methylenephosphonic acid) With calcium chloride; sodium hydroxide In water pH=6; Stage #2: at 130℃; for 120h; Autoclave;	72.2%

Amino tris(methylene phosphonic acid) Chemical Properties

Molecule structure of Amino Trimethylene Phosphonic Acid (ATMP) (CAS NO.6419-19-8) :

IUPAC Name: [bis(phosphonomethyl)amino]methylphosphonic acid
Molecular Weight: 299.049963 g/mol
Molecular Formula: C₃H₁₂NO₉P₃
Density: 2.094 g/cm³
Melting Point: ~215 °C
Boiling Point: 746.2 °C at 760 mmHg
Flash Point: 405.1 °C
Appreance: colourless liquid
Molar Volume: 142.7 cm³
Polarizability: 19.62*10^-24 cm³
Surface Tension: 143.1 dyne/cm
Enthalpy of Vaporization: 118.39 kJ/mol
Vapour Pressure: 2.29E-24 mmHg at 25 °C
XLogP3-AA: -7.2
H-Bond Donor: 6
H-Bond Acceptor: 10
Rotatable Bond Count: 6
Exact Mass: 298.972491
MonoIsotopic Mass: 298.972491
Topological Polar Surface Area: 176
Heavy Atom Count: 16
Complexity: 305
Canonical SMILES: C(N(CP(=O)(O)O)CP(=O)(O)O)P(=O)(O)O
InChI: InChI=1S/C3H12NO9P3/c5-14(6,7)1-4(2-15(8,9)10)3-16(11,12)13/h1-3H2,(H2,5,6,7)(H2,8,9,10)(H2,11,12,13) InChIKey: YDONNITUKPKTIG-UHFFFAOYSA-N
EINECS: 229-146-5
Product Categories: Phosphonate antiscalant; Organic Building Blocks; Phosphonic/Phosphinic Acids; Phosphorus Compounds

Amino tris(methylene phosphonic acid) Uses

Amino Trimethylene Phosphonic Acid (ATMP) (CAS NO.6419-19-8) is used for cooling water, boiler water, oilfield water treatment and corrosion inhibitor.

Amino tris(methylene phosphonic acid) Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
duck	LD50	oral	> 2510mg/kg (2510mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0990-0937,
quail	LD50	oral	> 2510mg/kg (2510mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0990-0937,
rabbit	LD50	skin	> 6310mg/kg (6310mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0990-0937,
rat	LD50	oral	2100mg/kg (2100mg/kg)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(2), Pg. 67, 1984.

Amino tris(methylene phosphonic acid) Safety Profile

Hazard Codes: Irritant Xi, Corrosive C
Risk Statements: 36-34
R36: Irritating to eyes
R34: Causes burns
Safety Statements: 26-45-36/37/39-25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S25: Avoid contact with eyes
RIDADR: 3265
WGK Germany: 1
RTECS: SZ9860000
F: 3-9
HazardClass: 8
PackingGroup: III

Amino tris(methylene phosphonic acid) Specification

Amino Trimethylene Phosphonic Acid (ATMP) (CAS NO.6419-19-8) is also called Nitrilotris(methylene))trisphosphonic acid ; 4-01-00-03070 (Beilstein Handbook Reference) ; AI3-51572 ; Amino, tris(methylene phosphonic acid) ; Aminotri(methylene phosphonic acid) ; Aminotris(methylphosphonic acid) . Amino Trimethylene Phosphonic Acid (ATMP) (CAS NO.6419-19-8) is stable and incompatible with bases, strong oxidizing agents.

Product Name

Amino tris(methylene phosphonic acid)

Synthetic route

Amino tris(methylene phosphonic acid) Chemical Properties

Amino tris(methylene phosphonic acid) Uses

Amino tris(methylene phosphonic acid) Toxicity Data With Reference

Amino tris(methylene phosphonic acid) Safety Profile

Amino tris(methylene phosphonic acid) Specification

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