• Name

  2-(2-BIPHENYLYLOXY)ETHANOL

• EINECS 231-355-1
• CAS No. 7501-02-2
• Article Data5
• CAS DataBase
• Density 1.111 g/cm³
• Solubility
• Melting Point
• Formula C₁₄H₁₄O₂
• Boiling Point 344.6 °C at 760 mmHg
• Molecular Weight 214.264
• Flash Point 151.4 °C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms 2-(2-phenylphenoxy)ethanol;beta-Hydroxyethyl ether of o-phenylphenol;Ethanol, 2- ([1,1-biphenyl]-2-yloxy)-;.beta.-Hydroxyethyl ether of o-phenylphenol;4-06-00-04581 (Beilstein Handbook Reference);Ethyl alcohol, 2-(o-biphenylyloxy)-;Ethanol, 2-((1,1-biphenyl)-2-yloxy)- (9CI);Ethanol,2-([1,1'-biphenyl]-2-yloxy)-;Ethyl alcohol, 2-(o-phenyl)phenoxy-;Ethanol, 2-(2-biphenylyloxy)-;
• PSA 29.46000
• LogP 2.72470

Synthetic route

96-49-1

[1,3]-dioxolan-2-one

90-43-7

2-Phenylphenol

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions

Conditions	Yield
With potassium carbonate at 160℃; for 1h; Temperature; Reagent/catalyst;	99.2%

107352-46-5

ethyl (<1,1'-biphenyl>-2-yloxy)acetate

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 1h;	95%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 1h;

90-43-7

2-Phenylphenol

107-07-3

2-chloro-ethanol

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions

Conditions	Yield
With potassium hydroxide

90-43-7

2-Phenylphenol

2-chloro-6-fluorobenzylhalide

2-chloro-6-fluorobenzylhalide

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / dimethylformamide / 4 h 2: LiAlH4 / tetrahydrofuran / 1 h / 0 °C View Scheme

90-43-7

2-Phenylphenol

diphenyl ether , 4-oxy-diphenyl

diphenyl ether , 4-oxy-diphenyl

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) NaH / 1.) DMF, 0 deg C, 2.) DMF, RT, overnight 2: 95 percent / lithium aluminium hydride / tetrahydrofuran / 1 h / 0 °C View Scheme

486-25-9

9-fluorenone

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

9,9-bis(3-phenyl-4-(2-hydroxyethoxy)phenyl)fluorene

Conditions

Conditions	Yield
With methanesulfonic acid; 3-mercaptopropionic acid In toluene at 50 - 80℃; for 5.5h; Time; Reagent/catalyst; Inert atmosphere;	90%
With 3-mercaptopropionic acid In 5,5-dimethyl-1,3-cyclohexadiene at 60℃; for 6h; Solvent;	87%
With sulfuric acid; 3-mercaptopropionic acid In 5,5-dimethyl-1,3-cyclohexadiene at 60 - 95℃; for 64h;

3240-94-6

N-(2-chlorethyl)morpholine

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

4-[2-(2-biphenyl-2-yloxy-ethoxy)-ethyl]-morpholine

Conditions

Conditions	Yield
With sodium; xylene

107-93-7

(E)-but-2-enoic acid

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

trans-crotonic acid-[2-(biphenylyl-(2)-oxy)-ethyl ester]

Conditions

Conditions	Yield
With benzenesulfonic acid; benzene at 90 - 120℃;

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

119-67-5

o-carboxybenzaldehyde

102706-07-0

3-(2-biphenyl-2-yloxy-ethoxy)-phthalide

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

124-63-0

methanesulfonyl chloride

2-(<1,1'-biphenyl>-2-yloxy)ethanol methanesulfonate

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 1h; Ambient temperature;

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

2-([1,1'-biphenyl]-2-yloxy)acetaldehyde

Conditions

Conditions	Yield
With Dess-Martin periodane In dichloromethane at 20℃; for 1h;
With Dess-Martin periodane In dichloromethane at 20℃; for 4h;

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

71939-50-9

dihydroartemisinin

A

C29H36O6

B

C29H36O6

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at -10 - -5℃; for 2h;

...Expand

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

107352-48-7

1-<2-(<1,1'-biphenyl>-2-yloxy)ethyl>-1H-imidazole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: triethylamine / tetrahydrofuran / 1 h / Ambient temperature 2: 34 percent / dimethylformamide / Ambient temperature View Scheme

3074-03-1

11H-Benzo[b]fluoren-11-one

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

C45H36O4

Conditions

Conditions	Yield
With sulfuric acid In toluene at 50℃; for 2h;

7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

140-88-5

ethyl acrylate

91442-24-9

2-phenylphenoxyethyl acrylate

Conditions

Conditions	Yield
With 2,4-dimethyl-6-tert-butylphenol; dioctyltin(IV) oxide at 78 - 120℃; for 4h; Reagent/catalyst;

Ethanol, 2-(o-biphenylyloxy)- Specification