Ethanol, 2,2-dimethoxy- supplier

Name
GLYCOLALDEHYDE DIMETHYL ACETAL
EINECS 250-398-7
CAS No. 30934-97-5
Article Data22
CAS DataBase
Density 1.009 g/cm³
Solubility Miscible with water.
Melting Point <-76°C
Formula C₄H₁₀O₃
Boiling Point 146.1 °C at 760 mmHg
Molecular Weight 106.122
Flash Point 42.2 °C
Transport Information
Appearance
Safety 23-24/25
Risk Codes 23-24/25
Molecular Structure
Hazard Symbols
Synonyms Glycolaldehyde,dimethyl acetal (6CI,7CI);2,2-Dimethoxyethanol;Hydroxyacetaldehyde dimethylacetal;2,2-dimethoxyethanol;
PSA 38.69000
LogP -0.40240

Synthetic route

: 23147-58-2, 110822-84-9, 110822-85-0
glycolaldehyde dimer

: 67-56-1
methanol

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
aminopropylated Silica-Gel hydrochloride (APSG*HCl) resin for 15h; Ambient temperature;	92%
With hydrogenchloride at 89.84℃; for 1h; Reagent/catalyst; Time;	72 %Chromat.

: 67-56-1
methanol

: 107-31-3
Methyl formate

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With titanium tetrachloride for 3h; Irradiation;	68%

: 67-56-1
methanol

: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
D-Xylose

A: 91-09-8, 612-05-5, 1825-00-9, 2500-78-9, 3867-83-2, 3945-28-6, 5328-63-2, 6206-67-3, 6207-01-8, 6207-03-0, 7404-24-2, 17289-61-1, 18449-76-8, 33509-64-7, 36793-06-3, 41897-31-8, 41897-32-9, 41897-33-0, 41897-34-1, 41897-37-4, 41897-38-5, 41897-39-6, 53448-52-5, 65137-86-2, 89615-04-3, 89615-05-4, 131233-91-5, 14703-09-4
methyl xyloside

B: 30934-97-5
2,2-dimethoxyethanol

C: 547-64-8
methyl lactate

Conditions

Conditions	Yield
With Ti-beta zeolite at 160℃; for 2h; Microwave irradiation;	A 48% B 7% C 11%
With Zr-beta zeolite at 160℃; for 2h; Microwave irradiation;	A 39% B 12% C 10%

...Expand

: 67-56-1
methanol

: 64-18-6
formic acid

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With titanium tetrachloride for 3h; Irradiation;	37%

: 67-56-1
methanol

: 141-46-8
Glycolaldehyde

A: 30934-97-5
2,2-dimethoxyethanol

B: 96-35-5
glycolic acid methyl ester

C: 107-21-1
ethylene glycol

Conditions

Conditions	Yield
tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;	A n/a B n/a C 35%
With triethylamine; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;	A n/a B n/a C 35%
With potassium carbonate; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 20℃; for 2 - 5h; Product distribution / selectivity;	A n/a B n/a C 27%
With caesium carbonate; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 20℃; for 2 - 5h; Product distribution / selectivity;	A n/a B n/a C 27%
With potassium hydroxide; dichloro(pentamethylcyclopentadienyl) iridium In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;	A n/a B n/a C 20%

...Expand

: 67-56-1
methanol

: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
D-Xylose

A: 98-01-1
furfural

B: 1453-62-9
2-furaldehyde dimethyl acetal

C: 91-09-8, 612-05-5, 1825-00-9, 2500-78-9, 3867-83-2, 3945-28-6, 5328-63-2, 6206-67-3, 6207-01-8, 6207-03-0, 7404-24-2, 17289-61-1, 18449-76-8, 33509-64-7, 36793-06-3, 41897-31-8, 41897-32-9, 41897-33-0, 41897-34-1, 41897-37-4, 41897-38-5, 41897-39-6, 53448-52-5, 65137-86-2, 89615-04-3, 89615-05-4, 131233-91-5, 14703-09-4
methyl xyloside

D: 30934-97-5
2,2-dimethoxyethanol

E: 547-64-8
methyl lactate

F: trans-2,5-dihydroxy-3-pentenoic acid methyl ester

Conditions

Conditions	Yield
With Sn-beta zeolite at 160℃; for 2h; Microwave irradiation;	A n/a B n/a C 32% D 6% E 11% F 12%

...Expand

: 67-56-1
methanol

: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
D-Xylose

A: 91-09-8, 612-05-5, 1825-00-9, 2500-78-9, 3867-83-2, 3945-28-6, 5328-63-2, 6206-67-3, 6207-01-8, 6207-03-0, 7404-24-2, 17289-61-1, 18449-76-8, 33509-64-7, 36793-06-3, 41897-31-8, 41897-32-9, 41897-33-0, 41897-34-1, 41897-37-4, 41897-38-5, 41897-39-6, 53448-52-5, 65137-86-2, 89615-04-3, 89615-05-4, 131233-91-5, 14703-09-4
methyl xyloside

B: 30934-97-5
2,2-dimethoxyethanol

C: 547-64-8
methyl lactate

D: trans-2,5-dihydroxy-3-pentenoic acid methyl ester

Conditions

Conditions	Yield
With Sn-beta zeolite at 160℃; for 2h; Microwave irradiation;	A 30% B 6% C 17% D 11%

...Expand

: 57346-02-8
methoxyoxirane

: 67-56-1
methanol

: 30934-97-5
2,2-dimethoxyethanol

: 127657-97-0
2-benzyloxy-1,1-dimethoxyethane

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With diethyl ether; ammonia; sodium

: 67-56-1
methanol

: 141-46-8
Glycolaldehyde

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With hydrogenchloride
With S2O82-/silicon MCM-41 at 100℃; for 3h;

: 67-56-1
methanol

: 2983-35-9
1,1,2-triacetoxy-ethane

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid

: 2177-18-6
vinyl acrylate

: 124-41-4
sodium methylate

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
(i) Br2, Et2O, (ii) /BRN= 3592982/; Multistep reaction;

: 67-56-1
methanol

: 138722-27-7
2-Methoxy-2-(trimethylsilyl)ethanol

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With tetraethylammonium tosylate anodic oxidation;

: 67-56-1
methanol

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With titanium tetrachloride for 15h; Irradiation; Yield given;

: 67-56-1
methanol

: 109-92-2
ethyl vinyl ether

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid; sulfuric acid 1a) MeOH, 0 deg C, 1.5h, 1b) RT, overnight, 2) 1h; Yield given. Multistep reaction;

: 109-92-2
ethyl vinyl ether

: 149-73-5
trimethyl orthoformate

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With dihydrogen peroxide; potassium hydrogencarbonate; acetonitrile; sulfuric acid 1a) MeOH, 0 deg C, 1.5h, 2) 12h, reflux, 2) MeOH, 1h, reflux; Yield given. Multistep reaction;

: 67-56-1
methanol

: 141-46-8
Glycolaldehyde

A: 30934-97-5
2,2-dimethoxyethanol

B: 96-35-5
glycolic acid methyl ester

Conditions

Conditions	Yield
dichloro(pentamethylcyclopentadienyl) iridium In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;
With potassium carbonate; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;
With caesium carbonate; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;
With potassium hydroxide; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;
With sodium hydroxide; tris(triphenylphosphine)ruthenium(II) chloride In 1,4-dioxane at 70℃; for 2 - 5h; Product distribution / selectivity;

...Expand

: 58-86-6
D-xylose

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 120℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 5 %Chromat. B 31 %Chromat.

: 58-86-6
D-xylose

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

C: 5837-73-0
methyl 2-hydroxybut-3-enoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 160℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 5 %Chromat. B 42 %Chromat. C 7 %Chromat.

...Expand

: 10323-20-3
D-Arabinose

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

C: 5837-73-0
methyl 2-hydroxybut-3-enoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 160℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 6 %Chromat. B 39 %Chromat. C 8 %Chromat.

...Expand

: 50-69-1
D-ribose

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

C: 5837-73-0
methyl 2-hydroxybut-3-enoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 160℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 5 %Chromat. B 38 %Chromat. C 8 %Chromat.

...Expand

: 1114-34-7
D-lyxose

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

C: 5837-73-0
methyl 2-hydroxybut-3-enoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 160℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 6 %Chromat. B 39 %Chromat. C 7 %Chromat.

...Expand

: 141-46-8
Glycolaldehyde

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

C: 5837-73-0
methyl 2-hydroxybut-3-enoate

D: 1361017-70-0
methyl 2-hydroxy-4-methoxybutanoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 120℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 7 %Chromat. B 10 %Chromat. C 25 %Chromat. D 19 %Chromat.
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 140℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 8 %Chromat. B 14 %Chromat. C 30 %Chromat. D 12 %Chromat.
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 160℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 7 %Chromat. B 16 %Chromat. C 27 %Chromat. D 6 %Chromat.

...Expand

: 141-46-8
Glycolaldehyde

A: 30934-97-5
2,2-dimethoxyethanol

B: 5837-73-0
methyl 2-hydroxybut-3-enoate

C: 1361017-70-0
methyl 2-hydroxy-4-methoxybutanoate

Conditions

Conditions	Yield
With zeotype catalyst Sn-Beta (Si/Sn = 400) In methanol at 100℃; under 15001.5 Torr; for 16h; Autoclave; Inert atmosphere;	A 8 %Chromat. B 13 %Chromat. C 26 %Chromat.

...Expand

: 23147-58-2, 110822-84-9, 110822-85-0
glycolaldehyde dimer

: 67-56-1
methanol

A: 30934-97-5
2,2-dimethoxyethanol

B: 1361017-70-0
methyl 2-hydroxy-4-methoxybutanoate

Conditions

Conditions	Yield
With tin (IV) chloride pentahydrate at 89.84℃; for 1h; Kinetics; Reagent/catalyst; Time;	A 54 %Chromat. B 10 %Chromat.

...Expand

: 67-56-1
methanol

: 532-20-7, 613-83-2, 7261-25-8, 7687-39-0, 13221-22-2, 14795-83-6, 15761-67-8, 20074-49-1, 25545-03-3, 25545-04-4, 32445-75-3, 34436-17-4, 36441-93-7, 36468-53-8, 37110-85-3, 37388-49-1, 38029-69-5, 40461-77-6, 40461-89-0, 41546-19-4, 41546-20-7, 41546-21-8, 41546-26-3, 41546-29-6, 41546-30-9, 41546-31-0, 126872-16-0, 131064-98-7
D-xylofuranose

A: 30934-97-5
2,2-dimethoxyethanol

B: 96-35-5
glycolic acid methyl ester

C: 547-64-8
methyl lactate

Conditions

Conditions	Yield
at 240℃; under 20686.5 Torr; for 1h; Inert atmosphere;

...Expand

: 67-56-1
methanol

: 497-09-6
(S)-glyceraldehyde

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
at 240℃; under 20686.5 Torr; for 1h; Inert atmosphere;

: 67-56-1
methanol

: 141-46-8
Glycolaldehyde

A: 30934-97-5
2,2-dimethoxyethanol

B: 547-64-8
methyl lactate

Conditions

Conditions	Yield
With mesoporous Zr-SBA-15 at 240℃; under 20686.5 Torr; for 1h; Inert atmosphere;

...Expand

: 89-91-8
Methyl dimethoxyacetate

: 30934-97-5
2,2-dimethoxyethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3h;	5.45 g

: 30934-97-5
2,2-dimethoxyethanol

: 58479-61-1
tert-butylchlorodiphenylsilane

: C20H28O3Si

Conditions

Conditions	Yield
With 1H-imidazole In tetrahydrofuran at 0 - 20℃; for 4h;	100%

: 30934-97-5
2,2-dimethoxyethanol

: 79-30-1
isobutyryl chloride

: 791121-01-2
isobutyric acid 2,2-dimethoxy-ethyl ester

Conditions

Conditions	Yield
With dmap; triethylamine at 20℃; for 16h;	99%
With dmap; triethylamine In ethyl acetate at 0 - 20℃; for 16h;	99%
With dmap; triethylamine In tert-butyl methyl ether at 0 - 20℃; for 16h;	99%

: 30934-97-5
2,2-dimethoxyethanol

: C11H9Cl2NO2

: C15H18ClNO5

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 20℃; for 12h;	98%

: 30934-97-5
2,2-dimethoxyethanol

: 100-39-0
benzyl bromide

: 127657-97-0
2-benzyloxy-1,1-dimethoxyethane

Conditions

Conditions	Yield
With sodium hydroxide In DMF (N,N-dimethyl-formamide) at 0 - 20℃;	93%
With sodium hydroxide In N,N-dimethyl-formamide at 0 - 20℃; for 16h;	60%

: 30934-97-5
2,2-dimethoxyethanol

: 201230-82-2
carbon monoxide

: methyl (2-(1-phenylvinyl)phenyl)carbamic chloride

: C21H23NO5

Conditions

Conditions	Yield
With dipotassium hydrogenphosphate; palladium diacetate; (S)-(-)-(6,6’-dimethoxybiphenyl-2,2’-diyl)bis(diphenylphosphine) In chlorobenzene; acetone at 20 - 80℃; for 30h; Schlenk technique; enantioselective reaction;	93%

...Expand

: 30934-97-5
2,2-dimethoxyethanol

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 2,2-dimethoxyethyl-2-nitrobenzenesulfonate

Conditions

Conditions	Yield
With TEA In dichloromethane at 20℃; for 3h;	92%

: 30934-97-5
2,2-dimethoxyethanol

: 333-20-0
potassium thioacyanate

: 32091-51-3
oxazole-2(3H)-thione

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 24h; Heating;	91%
With hydrogenchloride In ethanol; water at -5℃; for 24h; Reflux;	91%

: 10486-61-0
3-thienyl iodide

: 30934-97-5
2,2-dimethoxyethanol

: 1080649-34-8
3-(2,2-dimethoxyethoxy)thiophene

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In toluene at 110℃; for 36h;	91%

: 120-72-9
indole

: 30934-97-5
2,2-dimethoxyethanol

: 95331-90-1
2,2-di(1H-indol-3-yl)ethan-1-ol

Conditions

Conditions	Yield
With Montmorillonite K10 at 20℃; for 1.5h;	88%

: 30934-97-5
2,2-dimethoxyethanol

: 153034-80-1
2-Fluoro-4-iodo-3-methylpyridine

: 2-(2,2-dimethoxy-ethoxy)-4-iodo-3-methyl-pyridine

Conditions

Conditions	Yield
Stage #1: 2,2-dimethoxyethanol With sodium hydride In tetrahydrofuran Stage #2: 2-Fluoro-4-iodo-3-methylpyridine In tetrahydrofuran at 20℃; Further stages.;	86%

: 30934-97-5
2,2-dimethoxyethanol

: 75-05-8
acetonitrile

: 4-methoxy-2-methyl-4,5-dihydrooxazole

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 120h;	85%

: 30934-97-5
2,2-dimethoxyethanol

: 79-10-7
acrylic acid

: 116462-84-1
2,2-dimethoxyethyl acrylate

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran -78 deg C -> r.t.;	82%
With 2-chloro-1-methyl-pyridinium iodide; triethylamine In dichloromethane for 24h; Ambient temperature;	81%

: 30934-97-5
2,2-dimethoxyethanol

: 2614-88-2
sorbinyl chloride

: 134856-14-7
2,2-dimethoxyethyl (2E,4E)-2,4-hexadienoate

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran for 9h; Ambient temperature;	82%

: 612-62-4
2-Chloroquinoline

: 30934-97-5
2,2-dimethoxyethanol

: 2-(2,2-dimethoxyethoxy)quinoline

Conditions

Conditions	Yield
Stage #1: 2,2-dimethoxyethanol With sodium hydride In N,N-dimethyl-formamide for 0.5h; Stage #2: 2-Chloroquinoline In N,N-dimethyl-formamide at 20℃; for 24h;	81%

: 1810-72-6
2,6-dichloroquinoline

: 30934-97-5
2,2-dimethoxyethanol

: 6-chloro-2-(2,2-dimethoxyethoxy)quinoline

Conditions

Conditions	Yield
Stage #1: 2,2-dimethoxyethanol With sodium hydride In N,N-dimethyl-formamide for 0.5h; Stage #2: 2,6-dichloroquinoline In N,N-dimethyl-formamide at 20℃; for 24h;	81%

: 30934-97-5
2,2-dimethoxyethanol

: 400835-49-6
ethyl-2-O-benzyl-6-O-isobutyl-3,4-di-O-methyl-1-thio-α-D-mannopyranoside

: (3S,4S,5R,6R)-3-Benzyloxy-2-(2,2-dimethoxy-ethoxy)-6-isobutoxymethyl-4,5-dimethoxy-tetrahydro-pyran

Conditions

Conditions	Yield
With N-iodo-succinimide; 4 A molecular sieve; silver trifluoromethanesulfonate In dichloromethane; toluene at 0℃;	80%

: 30934-97-5
2,2-dimethoxyethanol

: 647029-76-3
ethyl-2-O-benzyl-6-O-isopropyl-3,4-di-O-methyl-1-thio-α-D-mannopyranoside

: (3S,4S,5R,6R)-3-Benzyloxy-2-(2,2-dimethoxy-ethoxy)-6-isopropoxymethyl-4,5-dimethoxy-tetrahydro-pyran

Conditions

Conditions	Yield
With N-iodo-succinimide; 4 A molecular sieve; silver trifluoromethanesulfonate In dichloromethane; toluene at 0℃;	80%

: 30934-97-5
2,2-dimethoxyethanol

: 817160-11-5
N-(2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)-4-nitrobenzenesulfonamide

: 817160-13-7
N-[2-(tert-butyldimethylsilanyloxymethyl)phenyl]-N-(2,2-dimethoxyethyl)-4-nitrobenzenesulfonamide

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at -20 - 30℃; for 21h; Mitsunobu reaction;	80%

: 3350-78-5
3,3-Dimethylacryloyl chloride

: 30934-97-5
2,2-dimethoxyethanol

: 134856-13-6
2,2-dimethoxyethyl 3-methyl-2-butenoate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0℃;	78%

: 30934-97-5
2,2-dimethoxyethanol

: 4224-69-5
methyl 2-(bromomethyl)propenoate

: 940279-21-0
2-(2,2-dimethoxy-ethoxymethyl)-acrylic acid methyl ester

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 0 - 20℃;	78%

: 120-72-9
indole

: 30934-97-5
2,2-dimethoxyethanol

: 108-24-7
acetic anhydride

: 88321-08-8
2,2-di-(1H-indol-3-yl)ethyl acetate

Conditions

Conditions	Yield
Stage #1: indole; 2,2-dimethoxyethanol at 20℃; for 1.5h; Stage #2: acetic anhydride With sodium acetate at 20℃; for 17h;	76%

...Expand

: 30934-97-5
2,2-dimethoxyethanol

: (3S,4S,5R,6R)-3-Benzyloxy-2-bromo-6-isopropoxymethyl-4,5-dimethoxy-tetrahydro-pyran

: (3S,4S,5R,6R)-3-Benzyloxy-2-(2,2-dimethoxy-ethoxy)-6-isopropoxymethyl-4,5-dimethoxy-tetrahydro-pyran

Conditions

Conditions	Yield
With silver carbonate In dichloromethane at 0℃;	75%

: 30934-97-5
2,2-dimethoxyethanol

: (3S,4S,5R,6R)-3-Benzyloxy-2-bromo-6-isobutoxymethyl-4,5-dimethoxy-tetrahydro-pyran

: (3S,4S,5R,6R)-3-Benzyloxy-2-(2,2-dimethoxy-ethoxy)-6-isobutoxymethyl-4,5-dimethoxy-tetrahydro-pyran

Conditions

Conditions	Yield
With 4 A molecular sieve; silver carbonate In dichloromethane at 0℃;	75%

: 30934-97-5
2,2-dimethoxyethanol

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 71989-33-8
Fmoc-Ser(tBu)-OH

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 1426238-82-5
(3S,6S,8aS)-6-methyl-7-((4-nitrophenyl)sulfonyl)-5-oxohexahydro-2H-oxazolo[3,2-a]pyrazine-3-carboxamide

Conditions

Conditions	Yield
Stage #1: Fmoc-Ser(tBu)-OH With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 16h; Rink amide resin; Stage #2: With piperidine In N,N-dimethyl-formamide at 20℃; for 0.333333h; Rink amide resin; Stage #3: 2,2-dimethoxyethanol; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; 4-Nitrobenzenesulfonyl chloride stereoselective reaction; Further stages;	75%

...Expand

: 30934-97-5
2,2-dimethoxyethanol

: 1612171-78-4
6-chloro-2-(chloromethyl)-1-isopropyl-imidazo [4,5-c]pyridine

: 6-chloro-2-(2,2-dimethoxyethoxymethyl)-1-isopropylimidazo[4,5-c]pyridine

Conditions

Conditions	Yield
Stage #1: 2,2-dimethoxyethanol With sodium hydride In N,N-dimethyl-formamide at 50℃; for 1h; Stage #2: 6-chloro-2-chloromethyl-1-isopropyl-1H-imidazo[4,5-c]pyridine In N,N-dimethyl-formamide at 50℃; for 2h;	75%

: 30934-97-5
2,2-dimethoxyethanol

: 113240-46-3
monoallyl malonate

: 68641-49-6
bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride

: allyl-2,2-dimethoxyethyl Malonate

Conditions

Conditions	Yield
With triethylamine In ethyl acetate	73%

...Expand

: 30934-97-5
2,2-dimethoxyethanol

: 2046-18-6
4-phenylbutyronitrile

: 4-methoxy-2-(3-phenylpropyl)-4,5-dihydrooxazole

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 120h;	73%

: 2024-83-1
veratronitrile

: 30934-97-5
2,2-dimethoxyethanol

: 2-(3,4-dimethoxyphenyl)-4-methoxy-4,5-dihydrooxazole

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In 1,2-dichloro-ethane at 20℃; for 24h; Concentration; Solvent; Temperature;	68%

Ethanol, 2,2-dimethoxy- Specification

The Ethanol, 2,2-dimethoxy-, with the CAS registry number 30934-97-5 and EINECS registry number 250-398-7, has the systematic name and IUPAC name of 2,2-dimethoxyethanol. And the molecular formula of the chemical is C₄H₁₀O₃. What's more, while dealing with this chemical, you should avoid contacting with skin and eyes, and do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).

The characteristics of Ethanol, 2,2-dimethoxy- are as followings: (1)ACD/LogP: -0.41; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.41; (4)ACD/LogD (pH 7.4): -0.41; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 14.31; (8)ACD/KOC (pH 7.4): 14.31; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 27.69 Å²; (13)Index of Refraction: 1.401; (14)Molar Refractivity: 25.56 cm³; (15)Molar Volume: 105.1 cm³; (16)Polarizability: 10.13×10^-24cm³; (17)Surface Tension: 29.3 dyne/cm; (18)Density: 1.009 g/cm³; (19)Flash Point: 42.2 °C; (20)Enthalpy of Vaporization: 44.63 kJ/mol; (21)Boiling Point: 146.1 °C at 760 mmHg; (22)Vapour Pressure: 1.85 mmHg at 25°C.

Preparation of Ethanol, 2,2-dimethoxy-: This chemical can be prepared by methanol and formic acid methyl ester. The reaction will need reagent titanium(IV) chloride. The reaction time is 3 hours with irridieation, and the yield is about 68%.

Uses of Ethanol, 2,2-dimethoxy-: It can react with 3-methyl-but-2-enoyl chloride to produce 2,2-dimethoxyethyl 3-methyl-2-butenoate. This reaction will need reagent pyridine, and the menstruum CH₂Cl₂. And the yield is about 78%.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: OCC(OC)OC
(2)InChI: InChI=1/C4H10O3/c1-6-4(3-5)7-2/h4-5H,3H2,1-2H3
(3)InChIKey: NYPNCQTUZYWFGG-UHFFFAOYAP

Product Name

GLYCOLALDEHYDE DIMETHYL ACETAL

Synthetic route

Ethanol, 2,2-dimethoxy- Specification

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