Glycine hydrochloride supplier

Name
Glycine hydrochloride
EINECS 227-841-8
CAS No. 6000-43-7
Article Data26
CAS DataBase
Density 1.27g/cm3
Solubility Slightly soluble in water
Melting Point 176-180 °C(lit.)
Formula C₂H₆ClNO₂
Boiling Point 240.9 °C at 760 mmHg
Molecular Weight 111.528
Flash Point 99.5 °C
Transport Information UN 1789 8/PG 3
Appearance White crystalline powder
Safety 24/25
Risk Codes 22
Molecular Structure
Hazard Symbols
Synonyms Glycine,hydrochloride (8CI,9CI);Aminoacetic acid hydrochloride;Glycocollhydrochloride;
PSA 63.32000
LogP 0.53200

Synthetic route

: 70288-73-2
methoxycarbonylamino acetic acid methyl ester

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; formic acid In water at 125℃; for 24h;	98%

: 74743-61-6
(3R)-3-<(1S,5R)-3-benzyl-7-oxo-4-oxa-2,6-diazabicyclo<3.2.0>hept-2-en-6-yl>-3,4,4-trimethylthietan-2-one

A: 103-82-2
phenylacetic acid

B: 6000-43-7
2-aminoethanoic acid hydrochloride

C: 88168-76-7
(2-RS)-2-amino-3-mercapto-2,3-dimethylbutanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride for 15h; Heating;	A 96% B n/a C n/a

...Expand

: 116963-47-4
Ethyl N-(trichloroacetyl)-2-aminoacetate

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With potassium hydroxide In methanol Ambient temperature;	95%

: 56-40-6
glycine

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water at 60℃; for 8h;	91%
With hydrogenchloride at 50℃; under 11400.9 Torr; Equilibrium constant; Thermodynamic data; Kinetics; various temperatures, protonation;
With hydrogenchloride In water

: 3545-80-0
hydroxyiminoacetic acid

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride In water at 20 - 25℃; for 16h;	61%

: 495-69-2
Hippuric Acid

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride

: 15166-50-4
N-(Trichloroacetyl)glycine

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride Heating;

: 367-62-4
ethyl 2-(2,2,2-trifluoroacetamido)acetate

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; potassium hydroxide 1.) methanol, 2 h, r. t.; Yield given. Multistep reaction;

: 1068-90-2
2-acetylaminomalonic acid diethyl ester

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; water

: 1172-18-5, 36105-20-1
flurazepam dihydrochloride

A: 6000-43-7
2-aminoethanoic acid hydrochloride

B: 5-chloro-2-<<2-(diethylamino)ethyl>amino>-2'-fluorobenzophenone hydrochloride

Conditions

Conditions	Yield
Product distribution;

: 7647-01-0
hydrogenchloride

: 540-61-4
2-aminoacetonitrile

A: ammonium chloride

B: 6000-43-7
2-aminoethanoic acid hydrochloride

...Expand

ethyl ester of/the/ glycine: ethyl ester of/the/ glycine

: 6000-43-7
2-aminoethanoic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride

: 7647-01-0
hydrogenchloride

: N-benzoyl-pentaglycyl-glycine

A: 6000-43-7
2-aminoethanoic acid hydrochloride

B: 65-85-0
benzoic acid

Conditions

Conditions	Yield
at 100℃; im geschlossenen Rohr;

...Expand

: 1186048-83-8
desmocyclopeptide

A: 6000-43-7
2-aminoethanoic acid hydrochloride

B: 17585-69-2, 27172-85-6, 28069-46-7, 74496-49-4, 79541-99-4
L-phenylalanine hydrochloride

C: 6003-05-0, 16428-74-3, 25616-13-1, 26570-06-9
L-alanine hydrochloride

D: 17694-98-3
L-isoleucine hydrochloride

E: 7776-34-3
L-proline hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water at 110℃; for 24h;

...Expand

: 1334715-68-2
versicoloritide B

A: 6000-43-7
2-aminoethanoic acid hydrochloride

B: 17585-69-2, 27172-85-6, 28069-46-7, 74496-49-4, 79541-99-4
L-phenylalanine hydrochloride

C: 7776-34-3
L-proline hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; water at 110℃; for 20h;

...Expand

: 1185-53-1
tris hydrochloride

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 71-23-8
propan-1-ol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 13049-01-9
glycine 1-propyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at 20 - 70℃; for 15h; Inert atmosphere;	98%

: 50-00-0
formaldehyd

: 6000-43-7
2-aminoethanoic acid hydrochloride

: C4H7ClNO4P

Conditions

Conditions	Yield
Stage #1: formaldehyd; 2-aminoethanoic acid hydrochloride With trimethyl phosphite at 30 - 40℃; for 1h; Stage #2: With phosphorus trichloride at 10℃; for 24h;	96%

: 112-53-8
1-dodecyl alcohol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 16194-11-9
dodecyloxycarbonylmethylammonium chloride

Conditions

Conditions	Yield
With hydrogenchloride at 110 - 120℃; for 8h;	95%
With hydrogenchloride at 110 - 120℃; for 8h;	91%

: 14283-99-9, 36186-03-5
bis(N-salicylaldimino)nickel(II)

: 6000-43-7
2-aminoethanoic acid hydrochloride

A: 75214-75-4
bis(N-salicylideneglycinato)Ni(II)

B: ammonium chloride

Conditions

Conditions	Yield
In methanol stirring the soln. for 30 min between room temp. and 60°C, pptn.; filtration, washing with water, recrystn. from acetone;	A 90% B n/a

...Expand

: 64-17-5
ethanol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 542-53-0
N-ethyl glycine hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at -20℃; for 2h; Inert atmosphere; Reflux;	90%

: 64-17-5
ethanol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at -20℃; for 2h; Reflux; Inert atmosphere;	90%

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 6000-43-7
2-aminoethanoic acid hydrochloride

: N-Hmb-Gly-OH

Conditions

Conditions	Yield
Stage #1: 2-Hydroxy-4-methoxybenzaldehyde; 2-aminoethanoic acid hydrochloride With sodium hydroxide In water at 20℃; for 3h; pH=9; Stage #2: With sodium tetrahydroborate; sodium hydroxide In water for 1h; Cooling with ice;	90%

: 86386-61-0
24-Norchenodeoxycholic acid

: 6000-43-7
2-aminoethanoic acid hydrochloride

: C27H45NO5

Conditions

Conditions	Yield
With triethylamine In acetone for 10h; Reagent/catalyst; Solvent; Reflux;	90%

: 112-30-1
1-Decanol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 39540-28-8
decyloxycarbonylmethylammonium chloride

Conditions

Conditions	Yield
With hydrogenchloride at 120 - 130℃;	89%
With hydrogenchloride at 110 - 120℃; for 8h;	89%

: 112-42-5
undecyl alcohol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: undecyloxycarbonylmethylammonium chloride

Conditions

Conditions	Yield
With hydrogenchloride at 110 - 120℃; for 8h;	86%

: 120-72-9
indole

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 1968-05-4
3,3'-diindolylmethane

Conditions

Conditions	Yield
With phosphotungstic acid 44-hydrate; alloxan monohydrate In N,N-dimethyl-formamide at 110℃;	86%

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 143-08-8
nonyl alcohol

: nonyloxycarbonylmethylammonium chloride

Conditions

Conditions	Yield
With hydrogenchloride at 110 - 120℃; for 8h;	85%

: C3H7O4PolS

: 6000-43-7
2-aminoethanoic acid hydrochloride

: mPEG-glycine

Conditions

Conditions	Yield
With sodium hydroxide In water at 37℃; for 72h; pH=10.5; Polyethylene glycol;	85%

: 474-25-9
chenodeoxycholic acid

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 70779-05-4
ethyl glycochenodeoxycholate

Conditions

Conditions	Yield
With triethylamine In acetone for 10h; Reflux;	85%

: 50-00-0
formaldehyd

: 3011-82-3
oxyde de dioctyl phosphine

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 1401662-39-2
N,N-bis(methylenedioctylphosphoryl)aminoethanoic acid

Conditions

Conditions	Yield
In acetonitrile for 3h; Reflux;	84%

...Expand

: 6000-43-7
2-aminoethanoic acid hydrochloride

: C72H76Cl4O8

: C80H92N4O16

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 20℃; for 12h;	80%

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 646517-54-6
(+/-)-(5-methyl-5-hexyl-2-oxothiophen-4-yloxy)acetic acid

: 646517-57-9
(+/-)-(5-methyl-5-hexyl-2-oxothiophen-4-yloxy)acetyl methyl glycinate

Conditions

Conditions	Yield
With tris(1,3-dihydro-2-oxobenzoxazolin-3-yl) phosphine oxide; triethylamine In acetonitrile at 20℃; for 0.333333h;	80%

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: [(2Z)-3-(dimethylamino)-2-[(E)-[(dimethylamino)methylidene]amino]prop-2-en-1-ylidene]dimethylazanium hexafluoro-λ5-phosphanuide

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl-formamide With trichlorophosphate at 10 - 15℃; for 1h; Stage #2: 2-aminoethanoic acid hydrochloride at 80℃; for 4h; Stage #3: With hexafluorophosphoric acid In water at 0℃;	78%

Glycine hydrochloride Chemical Properties

Molecular Structure of 2-Aminoacetic acid hydrochloride (CAS NO.6000-43-7):

IUPAC Name: 2-Aminoacetic acid hydrochloride
CAS: 6000-43-7
Formula: C₂H₆ClNO₂
Molecular Weight: 111.53
EINECS: 227-841-8
H bond acceptors: 3
H bond donors: 3
Freely Rotating Bonds: 2
Polar Surface Area: 29.54 Å²
Flash Point: 99.5 °C
Storage temp: 2-8°C
Water Solubility: Slightly soluble
Sensitive: Hygroscopic
Merck: 14,4491
BRN: 3909617
Melting Point: 176-180 °C(lit.)
Enthalpy of Vaporization: 52.63 kJ/mol
Boiling Point: 240.9 °C at 760 mmHg
Vapour Pressure: 0.0123 mmHg at 25°C
InChI
InChI=1/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H
Smiles
C(CN)(O)=O.Cl
Product Categories: alpha-amino acids; amino acids; biochemistry; omega-aminocarboxylic acids; omega-functional alkanols, carboxylic acids, amines & halides; alphabetic; amino acids, peptides and proteins; amino acidsanalytical standards; g;life sciences standards

Glycine hydrochloride Toxicity Data With Reference

orl-rat LD50:3340 mg/kg

JPMSAE Journal of Pharmaceutical Sciences. 62 (1973),49.

Glycine hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Glycine hydrochloride Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.
Safety Statements about 2-Aminoacetic acid hydrochloride (CAS NO.6000-43-7):
S24/25: Avoid contact with skin and eyes.
F10: Keep under argon.
RIDADR: UN 1789 8/PG 3
WGK Germany: 2
RTECS: MC0560000

Glycine hydrochloride Specification

The chemical synonyms of 2-Aminoacetic acid hydrochloride (CAS NO.6000-43-7) are Aminoethanoic acid hydrochloride ; Aminoacetic acid hydrochloride ; Glycocoll hydrochloride ; Glycine hcl ; Glycine-hcl buffer ; Glycine hydrochloride ; Glycine hydrochloride solution ; Aminoaceticacid.hcl=h-gly-oh.hcl . It shoud avoid breathing dust, vapor, mist, or gas and should be stored in a cool, dry place. Ingestion of large amounts may cause gastrointestinal irritation. Low hazard for usual industrial handling. It can be used to improve the bitter taste of beer, but also can be used in behalf of salts, nutritional supplements, flavor enhancer.

Product Name

Glycine hydrochloride

Synthetic route

Glycine hydrochloride Chemical Properties

Glycine hydrochloride Toxicity Data With Reference

Glycine hydrochloride Consensus Reports

Glycine hydrochloride Safety Profile

Glycine hydrochloride Specification

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