Glycine ethyl ester hydrochloride supplier

Name
Glycine ethyl ester hydrochloride
EINECS 210-787-4
CAS No. 623-33-6
Article Data55
CAS DataBase
Density 1 g/cm3
Solubility >1000 g/L (20 °C) in water
Melting Point 145-146 °C(lit.)
Formula C₄H₁₀ClNO₂
Boiling Point 109.5 °C at 760 mmHg
Molecular Weight 139.582
Flash Point
Transport Information
Appearance Crystalline
Safety 26-39-24/25
Risk Codes 41
Molecular Structure
Hazard Symbols Xi
Synonyms ethoxycarbonylmethylazanium;Glycine ethyl ester;Ethyl glycinate hydrochloride;Glycine hydrochloride ethyl ester;Ethyl aminoacetate hydrochloride;Ethyl glycinate;Glycine Ethylester Hydrochoride;H-Gly-OEt·HCl;Glycine Ethyl Ester HCl;
PSA 52.32000
LogP 1.01050

Synthetic route

: 77385-90-1
N,N-dibenzylglycine ethyl ester

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With 1,1,2-trichloroethane; 10% palladium on activated carbon; hydrogen In methanol under 760.051 Torr; for 1h; chemoselective reaction;	99%

: 64-17-5
ethanol

: 56-40-6
glycine

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at 25 - 30℃; for 0.583333h; microwave irradiation;	98%
With thionyl chloride Reflux;	97%
With thionyl chloride at -10 - 20℃; for 2h; Heating / reflux;	90.4%

: 85231-98-7
C13H26NO7P

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In benzene Ambient temperature;	91%

: 56-40-6
glycine

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride In ethanol at -10℃; for 2h; Heating / reflux;	90.4%
With thionyl chloride In ethanol for 2h;	90.4%

: 64-17-5
ethanol

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at -20℃; for 2h; Reflux; Inert atmosphere;	90%

: 6378-11-6
ethyl chlorosulfite

: 56-40-6
glycine

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
at -5 - 60℃; for 4h;	85%

: 637-81-0
ethyl-2-azidoacetate

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With triphenylphosphine In tetrahydrofuran; water for 12h; Ambient temperature;	83%

: 14011-27-9
ethyl chloronitroacetate

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol at 35 - 40℃;	65.3%

: 626-35-7
nitroacetic acid ethyl ester

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With ammonium formate; palladium on activated charcoal In methanol for 0.333333h; Ambient temperature;	64%

: 64-17-5
ethanol

: 80478-56-4
ethyl N-(2-diethoxyacetyl)glycinate

A: 623-33-6
glycine ethyl ester hydrochloride

B: 6065-82-3
Ethyl diethoxyacetate

Conditions

Conditions	Yield
With hydrogenchloride for 3h; Heating;	A 35% B 38%
With hydrogenchloride for 3h; Product distribution; Heating;	A 35% B 38%

...Expand

: 64-17-5
ethanol

: 144232-41-7
ethoxycarbonylmethyl-hexamethylenetetraminium; chloride

: 623-33-6
glycine ethyl ester hydrochloride

: 64-17-5
ethanol

: 2184-96-5
glycinyl chloride hydrochloride

: 623-33-6
glycine ethyl ester hydrochloride

: 7647-01-0
hydrogenchloride

: 2185-00-4
1,3-oxazolidine-2,5-dione

: 623-33-6
glycine ethyl ester hydrochloride

: 7647-01-0
hydrogenchloride

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
bei Siedetemperatur;

: 7647-01-0
hydrogenchloride

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

A: 1145-81-9
ethyl 2-(benzyloxycarbonylamino)ethanoate

B: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
at 0℃;

...Expand

: 861366-27-0
N,N-dichloro-glycine ethyl ester

A: 7647-01-0
hydrogenchloride

B: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
Zersetzung;

: 7647-01-0
hydrogenchloride

: 64-17-5
ethanol

: 1906-82-7
ethyl acetamidoacetate

A: 623-33-6
glycine ethyl ester hydrochloride

B: 141-78-6
ethyl acetate

...Expand

: 7647-01-0
hydrogenchloride

: 861554-12-3
N-(3-azidocarbonyl-propionyl)-glycyl azide

A: 623-33-6
glycine ethyl ester hydrochloride

B: 123-25-1
succinic acid diethyl ester

...Expand

ethanolic N-benzyloxycarbonyl-glycine: ethanolic N-benzyloxycarbonyl-glycine

A: 1145-81-9
ethyl 2-(benzyloxycarbonylamino)ethanoate

B: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride at 0℃;

: 64269-79-0
Carbonyldiimidazole

A: 623-33-6
glycine ethyl ester hydrochloride

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
In dichloromethane

: 170622-26-1
5-(((-4-n-decylphenyl)amino)carbonyl)-3-methoxypyridine-2-carboxylic acid

A: 170621-73-5
5-(((4-n-Decylphenyl)amino)carbonyl)-3-methoxypyridine-2-carboxylic acid N-(ethoxycarbonylmethyl)amide

B: 623-33-6
glycine ethyl ester hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In tetrahydrofuran

: 762-04-9, 123-22-8
Diethyl phosphonate

A: 623-33-6
glycine ethyl ester hydrochloride

B paraformaldehyde: paraformaldehyde

Conditions

Conditions	Yield
With sodium methylate In methanol

: 1738-87-0
Z-Leu-ONp

: 623-33-6
glycine ethyl ester hydrochloride

: 2867-06-3
Benzyloxycarbonylleucyl-glycine ethyl ester

Conditions

Conditions	Yield
With triethylamine In chloroform at 14℃; for 11h; Condensation;	100%
With chloroform; triethylamine

: 623-33-6
glycine ethyl ester hydrochloride

: 98-88-4
benzoyl chloride

: 1499-53-2
ethyl hippurate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0℃; for 1h;	100%
With triethylamine In dichloromethane at 0℃; for 1h;	99.4%
Stage #1: glycine ethyl ester hydrochloride With triethylamine In dichloromethane for 0.166667h; Stage #2: benzoyl chloride In dichloromethane at 20℃; Further stages.;	74%

: 50-00-0
formaldehyd

: 67883-62-9
2-methylallyltributyltin

: 623-33-6
glycine ethyl ester hydrochloride

: [Bis-(3-methyl-but-3-enyl)-amino]-acetic acid methyl ester

Conditions

Conditions	Yield
In ethanol; chloroform; water for 4h; Ambient temperature;	100%

...Expand

: 24424-99-5
di-tert-butyl dicarbonate

: 623-33-6
glycine ethyl ester hydrochloride

: 14719-37-0
ethyl 2-(tert-butoxycarbonylamino)acetate

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 0 - 50℃;	100%
With sodium hydrogencarbonate In acetonitrile at 20℃; for 16h;	99%
With triethylamine In tetrahydrofuran at 0℃; for 36h;	98%

: 1142-20-7
N-Cbz-Ala

: 623-33-6
glycine ethyl ester hydrochloride

: 2503-32-4
ethyl N-(benzyloxycarbonyl)-L-alanylglycinate

Conditions

Conditions	Yield
With chloroformic acid ethyl ester In dichloromethane for 0.166667h; Condensation; Heating;	100%
With TEA; diphenyl (2,3-dihydro-2-thioxo-3-benzoxazolyl)phosphonate In dichloromethane for 2h; Ambient temperature;	99%
Stage #1: N-Cbz-Ala With 1,1'-carbonyldioxydi[2(1H)-pyridone] In dichloromethane at 20℃; Stage #2: glycine ethyl ester hydrochloride With triethylamine In dichloromethane at -18℃;	99%

: 623-33-6
glycine ethyl ester hydrochloride

: 115975-33-2
N,N-Dimethyl-2,4-bis(trifluoroacetyl)-1-naphthylamine

: 126045-83-8
[2,4-Bis-(2,2,2-trifluoro-acetyl)-naphthalen-1-ylamino]-acetic acid ethyl ester

Conditions

Conditions	Yield
With sodium acetate In water; acetonitrile for 4h; Product distribution; Ambient temperature; other amino acids investigated;	100%
With sodium acetate In water; acetonitrile for 4h; Ambient temperature;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 115975-33-2
N,N-Dimethyl-2,4-bis(trifluoroacetyl)-1-naphthylamine

: 126045-87-2, 126045-88-3
3-Hydroxy-5-(2,2,2-trifluoro-acetyl)-3-trifluoromethyl-2,3-dihydro-1H-benzo[g]indole-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With triethylamine In acetonitrile for 18h; Product distribution; Ambient temperature; other amino acids investigated;	100%
With triethylamine In acetonitrile for 18h; Ambient temperature;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 100-52-7
benzaldehyde

: 40682-54-0
ethyl N-benzylideneglycinate

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With ammonia In dichloromethane; water Stage #2: benzaldehyde With magnesium sulfate In dichloromethane at 20℃; Inert atmosphere;	100%
With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 10h;	98%
With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 8h; Time;	94%

: 623-33-6
glycine ethyl ester hydrochloride

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 95218-34-1
ethyl 2-{[(2,4-dimethoxyphenyl)methyl]amino}acetate

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; triethylamine In 1,2-dichloro-ethane for 17h;	100%
With sodium tetrahydroborate; triethylamine In methanol; ethanol for 1h; Ambient temperature;	59%
Stage #1: glycine ethyl ester hydrochloride; 2,4-Dimethoxybenzaldehyde With triethylamine In acetonitrile at 20℃; for 1h; Inert atmosphere; Stage #2: With sodium tris(acetoxy)borohydride at 20℃; for 18h; Inert atmosphere;	49%
Stage #1: glycine ethyl ester hydrochloride; 2,4-Dimethoxybenzaldehyde With triethylamine In 1,1-dichloroethane for 1h; Stage #2: With water; sodium tris(acetoxy)borohydride In 1,1-dichloroethane for 72h; Stage #3: With sodium hydrogencarbonate In 1,1-dichloroethane; water

: 623-33-6
glycine ethyl ester hydrochloride

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 2766-31-6
ethyl (N-benzoxycarbonyl-L-prolyl)glycinate

Conditions

Conditions	Yield
Stage #1: N-Benzyloxycarbonyl-L-proline With 1,1'-carbonyldioxydi[2(1H)-pyridone] In dichloromethane at 20℃; Stage #2: glycine ethyl ester hydrochloride With triethylamine In dichloromethane at -18℃;	100%
Stage #1: N-Benzyloxycarbonyl-L-proline With iodine; N-ethyl-N,N-diisopropylamine; phosphorous acid trimethyl ester In ethyl acetate for 0.166667h; Cooling with ice; Inert atmosphere; Stage #2: glycine ethyl ester hydrochloride In ethyl acetate at 20℃; for 6h; Inert atmosphere; Cooling with ice;	87%
With 2,6-dimethylpyridine; 1-[(1-(cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino)]-uronium hexafluorophosphate In tetrahydrofuran; water at 20 - 25℃; Solvent;	85%
With N,N'-dicyclopentylcarbodiimide; triethylamine In dichloromethane for 24h;	62%
With Lawessons reagent; triethylamine 1.) CH2Cl2, 20 min, room temperature 2.) 0 deg C for 1 h, room temperature for 15 h.; Yield given. Multistep reaction;

: 623-33-6
glycine ethyl ester hydrochloride

: 221636-53-9
N,N-dimethyl-5,7-bis(trifluoroacetyl)-8-quinolylamine

: N-[5,7-bis(trifluoroacetyl)-8-quinolyl]glycine ethyl ester

Conditions

Conditions	Yield
With water; sodium acetate In acetonitrile for 6h; Ambient temperature;	100%
With sodium acetate In water; acetonitrile at 25℃; for 6h; Substitution;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 284490-18-2
(2R,3aS,9aR)-2-((Z)-1-Cyano-2-hydroxy-vinyl)-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester

: 222854-85-5
(2R,3aS,9aR)-2-[(Z)-1-Cyano-2-(ethoxycarbonylmethyl-amino)-vinyl]-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester

Conditions

Conditions	Yield
With sodium acetate In methanol at 20℃; for 16h; Condensation;	100%

: 21792-87-0
5-chloro-2-nitrobenzenesulfonyl chloride

: 623-33-6
glycine ethyl ester hydrochloride

: 441799-46-8
ethyl 2-(5-chloro-2-nitrobenzenesulfonamido)acetate

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 2.5h;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 742106-26-9
N-{3-[(3,5-dimethylphenyl)sulfonyl]-5-chloro-1H-indole-2-carbonyl}-D,L-alanine

: 742106-28-1
N-{3-[(3,5-dimethylphenyl)sulfonyl]-5-chloro-1H-indole-2-carbonyl}-D,L-alanylglycine ethyl ester

Conditions

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 72h;	100%

: 102153-63-9
6-chloronaphth-2-ylsulfonyl chloride

: 623-33-6
glycine ethyl ester hydrochloride

: 318986-24-2
ethyl 2-[(6-chloronaphthalen-2-ylsulfonyl)amino]acetate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 1h;	100%
With hydrogenchloride; triethylamine In hexane; dichloromethane

: 623-33-6
glycine ethyl ester hydrochloride

: 587-04-2
3-Chlorobenzaldehyde

: [(4-chloro-benzylidene)-amino]-acetic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: m-Chlorobenzaldehyde In dichloromethane at 20℃; for 16h; Inert atmosphere;	100%
With magnesium sulfate; triethylamine In tetrahydrofuran
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 1h; Stage #2: m-Chlorobenzaldehyde In dichloromethane at 20℃;
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 1h; Stage #2: m-Chlorobenzaldehyde In dichloromethane at 20℃;

: 19810-31-2
Benzyloxyacetyl chloride

: 623-33-6
glycine ethyl ester hydrochloride

: N-benzyloxyacetylglycine ethyl ester

Conditions

Conditions	Yield
With hydrogenchloride; dmap In dichloromethane	100%

: C19H35F2NO3Si

: 623-33-6
glycine ethyl ester hydrochloride

: 1147117-58-5
Boc-D-Val-Ψ[(Z)CF=CH]-Gly-Gly-OEt

Conditions

Conditions	Yield
Stage #1: C19H35F2NO3Si With potassium cyanide; 18-crown-6 ether In N,N-dimethyl-formamide at 0℃; Brook rearrangement; Stage #2: glycine ethyl ester hydrochloride With triethylamine In N,N-dimethyl-formamide at 0℃; for 2h; optical yield given as %de; diastereoselective reaction;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 74-89-5
methylamine

: 49755-94-4
glycine-N-methylamide hydrochloride

Conditions

Conditions	Yield
In ethanol at 20℃; for 16h;	100%
In ethanol at 20℃; for 16h;	100%
In water at 20℃; for 3h;

: 26260-02-6
2-iodobenzaldehyde

: 623-33-6
glycine ethyl ester hydrochloride

: ethyl 2-[N-(2-iodobenzyl)amino]acetate

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid; triethylamine In dichloromethane at 20℃; for 19h; Inert atmosphere;	100%

: 37076-47-4
2-(trityloxy)acetic acid

: 623-33-6
glycine ethyl ester hydrochloride

: 1275616-91-5
ethyl (2-trityloxyacetylamino)acetate

Conditions

Conditions	Yield
With 4-methyl-morpholine; dicyclohexyl-carbodiimide In acetonitrile at 0 - 4℃; for 3.5h; Inert atmosphere;	100%

: 14371-10-9
(E)-3-phenylpropenal

: 623-33-6
glycine ethyl ester hydrochloride

: C13H15NO2

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With triethylamine In dichloromethane at 20℃; for 0.5h; Inert atmosphere; Stage #2: (E)-3-phenylpropenal In dichloromethane at 20℃; for 3h; Inert atmosphere;	100%
With magnesium sulfate; triethylamine In chloroform for 1.83333h; Inert atmosphere;
With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 8h;

: 737740-52-2
8-Methoxy-2-(trifluoromethyl)quinoline-5-carbonyl chloride

: 623-33-6
glycine ethyl ester hydrochloride

: C15H13F3N2O4

Conditions

Conditions	Yield
With triethylamine	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 107-14-2
chloroacetonitrile

: 1417647-13-2
ethyl 2-((cyanomethyl)amino)acetate hydrochloride

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride; chloroacetonitrile With potassium carbonate; sodium iodide In acetonitrile at 80℃; for 18h; Stage #2: With hydrogenchloride In diethyl ether	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 874-42-0
2,4-dichlorobenzaldeyhde

: (2,4-dichlorobenzylideneamino)acetic acid ethyl ester

Conditions

Conditions	Yield
With sodium sulfate; triethylamine In dichloromethane at 0 - 20℃; for 15h;	100%
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: 2,4-dichlorobenzaldeyhde In dichloromethane at 20℃; for 12h; Inert atmosphere;

: 623-33-6
glycine ethyl ester hydrochloride

: 1498-51-7
ethyl phosphodichloridite

: 2-((chloro(ethoxy)phosphoryl)amino)acetic acid ethyl ester

Conditions

Conditions	Yield
With triethylamine In dichloromethane at -78 - 20℃; for 2h; Inert atmosphere;	100%

: 623-33-6
glycine ethyl ester hydrochloride

: 529-20-4
2-methylphenyl aldehyde

: 1225330-57-3
(E)-ethyl 2-((2-methylbenzylidene)amino)acetate

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Stage #2: 2-methylphenyl aldehyde In dichloromethane at 20℃; for 16h;	100%
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: 2-methylphenyl aldehyde In dichloromethane at 20℃; for 16h; Inert atmosphere;	100%
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane for 0.0833333h; Stage #2: 2-methylphenyl aldehyde In dichloromethane at 20℃; for 16h;
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Stage #2: 2-methylphenyl aldehyde In dichloromethane at 20℃; for 16h;

: 2-isopropoxynicotinaldehyde

: 623-33-6
glycine ethyl ester hydrochloride

: (E)-ethyl 2-(((2-isopropoxypyridin-3-yl)methylene)amino)acetate

Conditions

Conditions	Yield
With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 16h;	100%
With magnesium sulfate; triethylamine	100%

: 3132-99-8
m-bromobenzoic aldehyde

: 623-33-6
glycine ethyl ester hydrochloride

: (E)-ethyl 2-((3-bromobenzylidene)amino)acetate

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane for 0.0833333h; Stage #2: m-bromobenzoic aldehyde In dichloromethane at 20℃; for 16h;	100%
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Stage #2: m-bromobenzoic aldehyde In dichloromethane at 20℃; for 16h;	100%

: 1-isopropyl-1H-pyrazole-5-carbaldehyde

: 623-33-6
glycine ethyl ester hydrochloride

: (E)-ethyl 2-(((1-isopropyl-1H-pyrazol-5-yl)methylene)amino)acetate

Conditions

Conditions	Yield
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane for 0.0833333h; Stage #2: 1-isopropyl-1H-pyrazole-5-carbaldehyde In dichloromethane at 20℃; for 16h;	100%
Stage #1: glycine ethyl ester hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.0833333h; Stage #2: 1-isopropyl-1H-pyrazole-5-carbaldehyde In dichloromethane at 20℃; for 16h;	100%

Glycine ethyl ester hydrochloride Chemical Properties

Molecular Structure of Glycine ethyl ester hydrochloride (CAS NO.623-33-6):

IUPAC Name: ethyl 2-aminoacetate hydrochloride
Name : Glycine ethyl ester hydrochloride
Molecular Formula : C₄H₉NO₂.HCl; C₄H₁₀ClNO₂
Molecular Weight : 139.58
CAS Registry Number : 623-33-6
EINECS : 210-787-4
BRN: 3594034
H bond acceptors: 3
H bond donors: 2
Freely Rotating Bonds: 4
Polar Surface Area: 26.3 Å²
Storage temp: Store at RT
Melting point: 145-148 ^oC
Water solubility: >1000 g/L (20^oC)
Solubility: >1000 g/L (20 °C)
Sensitive: Hygroscopic
Enthalpy of Vaporization: 34.82 kJ/mol
Boiling Point: 109.5 °C at 760 mmHg
Vapour Pressure: 24.7 mmHg at 25°C
InChI
InChI=1/C4H9NO2.ClH/c1-2-7-4(6)3-5;/h2-3,5H2,1H3;1H
Smiles
C(OCC)(C[NH3+])=O.[ClH-]
Product Categories: Food and Feed Additive; Amino Acid Derivatives; Amino Acids; Glycine [Gly, G]; Amino Acids and Derivatives; Amino Acid Ethyl Esters; Amino Acids (C-Protected); Biochemistry; Amino hydrochloride

Glycine ethyl ester hydrochloride Toxicity Data With Reference

ipr-mus LD50:750 mg/kg

NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .

Glycine ethyl ester hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Glycine ethyl ester hydrochloride Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NO_x, HCl, and Cl⁻.
Hazard Codes: Irritant Xi
Risk Statements: 41
R41:Risk of serious damage to the eyes.
Safety Statements: 26-39-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39:Wear eye / face protection.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: MC0525000
HS Code: 29224995

Glycine ethyl ester hydrochloride Specification

Glycine ethyl ester hydrochloride , with CAS number of 623-33-6, can be called Glycineethylesterhydrochlor ; Glycocollethylesterhydrochloride ; usafdo-10 ; H-gly-oet HCl ; Glycine ethyl ester ; Glycine ethyl ester HCl ; Glycine ethyl ester hydrochloride ; Glycine-oet HCl .

Glycine ethyl ester hydrochloride (CAS NO.623-33-6) is pesticide and pharmaceutical intermediates, also used in biochemical research. It has been prepared by the action of absolute alcohol and hydrogen chloride on glycine;from glycyl chloride and alcohol;by the action of ammonia or hexamethylenetetramine on chloroacetic acid, and subsequent hydrolysis with alcoholic hydrochloric acid; by the action of hydrogen chloride and alcohol onmethyleneaminoacetonitrile;and by the reduction of ethyl cyanoformate or the corresponding imido ester hydrochloride.

Product Name

Glycine ethyl ester hydrochloride

Synthetic route

Glycine ethyl ester hydrochloride Chemical Properties

Glycine ethyl ester hydrochloride Toxicity Data With Reference

Glycine ethyl ester hydrochloride Consensus Reports

Glycine ethyl ester hydrochloride Safety Profile

Glycine ethyl ester hydrochloride Specification

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