Product Name

  • Name

    L-Cysteine hydrochloride monohydrate

  • EINECS 200-157-7
  • CAS No. 7048-04-6
  • Article Data2
  • CAS DataBase
  • Density 1.54 g/cm3
  • Solubility 1 M at 20 °C in water, clear, colorless
  • Melting Point 175 °C
  • Formula C3H8ClNO2S.H2O
  • Boiling Point 293.9 °C at 760 mmHg
  • Molecular Weight 175.636
  • Flash Point 131.5 °C
  • Transport Information
  • Appearance white crystalline powder
  • Safety 26-36
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 7048-04-6 (L-Cysteine hydrochloride monohydrate)
  • Hazard Symbols IrritantXi
  • Synonyms Cysteine,hydrochloride, monohydrate, L- (8CI);L-Cysteine, hydrochloride, monohydrate(9CI);
  • PSA 111.35000
  • LogP 0.76610

Synthetic route

dimethyltin oxide
2273-45-2

dimethyltin oxide

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

chlorodimethyltin(IV) L-cysteine monohydrate

chlorodimethyltin(IV) L-cysteine monohydrate

Conditions
ConditionsYield
In hydrogenchloride99%
hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

barium hydroxide octahydrate

barium hydroxide octahydrate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

1.5Ba(2+)*Co(C3H5NO2S)3(3-)*5H2O = Ba1.5[Co(C3H5NO2S)3]*5H2O

1.5Ba(2+)*Co(C3H5NO2S)3(3-)*5H2O = Ba1.5[Co(C3H5NO2S)3]*5H2O

Conditions
ConditionsYield
In water (argon); 70°C, 2 h; elem. anal.;96%
L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

2,4-Dihydroxybenzaldehyde
95-01-2

2,4-Dihydroxybenzaldehyde

(4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid
1367664-23-0

(4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In ethanol; water at 20℃; for 14h;95.8%
Divinyl sulfone
77-77-0

Divinyl sulfone

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

C7H13NO4S2*ClH

C7H13NO4S2*ClH

Conditions
ConditionsYield
In methanol at 50℃; for 100h;95%
L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

potassium dicyanoaurate

potassium dicyanoaurate

[(L-cysteinato)gold(I)]

[(L-cysteinato)gold(I)]

Conditions
ConditionsYield
In water mixing of the components in double-distd. water and standing at 4°C overnight; sepn. of the ppt., washing with EtOH and dry Et2O and drying (P2O5, vac.); elem. anal.;88.4%
acetic anhydride
108-24-7

acetic anhydride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

N-acetylcystein
616-91-1

N-acetylcystein

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran; water at 10 - 60℃; for 37h; pH=4 - 5; Inert atmosphere;85%
hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

lithium hydroxide monohydrate
1310-66-3

lithium hydroxide monohydrate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

trilithium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) heptahydrate

trilithium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) heptahydrate

Conditions
ConditionsYield
In water 70°C, 2 h, addn. of EtOH, stirring (20°C, 12 h); elem. anal.;82%
hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

sodium hydroxide
1310-73-2

sodium hydroxide

trisodium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) * 11 H2O

trisodium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) * 11 H2O

Conditions
ConditionsYield
In water 70°C, 2 h, addn. of EtOH, stirring (20°C, 12 h); elem. anal.;80%
hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

potassium hydroxide

potassium hydroxide

tripotassium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) * 6.5 H2O

tripotassium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) * 6.5 H2O

Conditions
ConditionsYield
In water 70°C, 2 h, addn. of EtOH, stirring (20°C, 12 h); elem. anal.;80%
hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

rubidium hydroxide

rubidium hydroxide

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

trirubidium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) nonahydrate

trirubidium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) nonahydrate

Conditions
ConditionsYield
In water 70°C, 2 h, addn. of EtOH, stirring (20°C, 12 h); elem. anal.;80%
cesium hydroxide

cesium hydroxide

hexammine cobalt(III) chloride

hexammine cobalt(III) chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

tricesium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) octahydrate

tricesium fac-Δ-tris(R-cysteinato-N,S)cobaltate(III) octahydrate

Conditions
ConditionsYield
In water 70°C, 2 h, addn. of EtOH, stirring (20°C, 12 h); elem. anal.;80%
2-fluorobenzyl chloride
345-35-7

2-fluorobenzyl chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

A

(2R)-2-amino-3-(2-fluorobenzylthio)propanol

(2R)-2-amino-3-(2-fluorobenzylthio)propanol

B

(2R)-2-amino-3-(2-fluorobenzylthio)propionic acid

(2R)-2-amino-3-(2-fluorobenzylthio)propionic acid

Conditions
ConditionsYield
With hydrogenchloride In methanol; waterA n/a
B 74.8%
2,4-dihydroxybenzonitrile
64419-24-5

2,4-dihydroxybenzonitrile

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

C10H9NO4S
57980-69-5

C10H9NO4S

Conditions
ConditionsYield
With sodium hydrogencarbonate In methanol69%
ammonium tetrathiotungstate
13862-78-7

ammonium tetrathiotungstate

potassium chloride

potassium chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

potassium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} pentahydrate

potassium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} pentahydrate

Conditions
ConditionsYield
With HCl; KOH In water dropwise addn. of concd. HCl to aq. W compd. soln. with stirring; addn. of L-cysteine; stirring, several min; adjusting to pH 7 (KOH); heating at 50-60°C, 30 min; addn. of KCl; cooling to room temp.; storage in refrigerator overnight; crystn.; filtration; washing (methanol); recrystn. by dissoln. in hot water; filtration; addn. of KCl; allowing to stand overnight in a refrigerato; crystn.; elem. anal.;50%
water
7732-18-5

water

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

2-chloro-3-(1H-imidazol-4-yl)propanoic acid
6630-42-8, 17561-26-1, 17561-27-2, 36392-60-6

2-chloro-3-(1H-imidazol-4-yl)propanoic acid

2-amino-3-(1-carboxy-2-(1H-imidazol-4-yl)ethylthio)propanoic acid

2-amino-3-(1-carboxy-2-(1H-imidazol-4-yl)ethylthio)propanoic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 72h; Inert atmosphere;50%
ammonium tetrathiotungstate
13862-78-7

ammonium tetrathiotungstate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

ammonium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} trihydrate

ammonium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} trihydrate

Conditions
ConditionsYield
With NH4Cl; HCl; NH3 In water dropwise addn. of HCl to aq. W compd. soln. with stirring; addn. of cysteine; stirring, several min; adjusting pH to 7 (NH3); heating, 50-60°C, 30 min; addn. of NH4Cl; cooling to room temp.; storage in refrigerator overnight; crystn.; filtration; washing (methanol); recrystn.; elem. anal.;46%
4-nitrobenzyl chloride
100-14-1

4-nitrobenzyl chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

A

(2R)-2-amino-3-(4-nitrobenzylthio)propanol

(2R)-2-amino-3-(4-nitrobenzylthio)propanol

B

L-2-amino-3-(4-nitrobenzylthio)propionic acid
90899-86-8

L-2-amino-3-(4-nitrobenzylthio)propionic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxideA n/a
B 45.9%
ammonium tetrathiotungstate
13862-78-7

ammonium tetrathiotungstate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

sodium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} trihydrate

sodium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} trihydrate

Conditions
ConditionsYield
With NaCl; HCl In water dropwise addn. of HCl to aq. W compd. soln. with stirring; addn. of cysteine; stirring, several min; adjusting pH to 7 (NaOH); heating, 50-60°C, 30 min; addn. of NaCl; cooling to room temp.; storage in refrigerator overnight; crystn.; filtration; washing (methanol); recrystn.; elem. anal.;40%
sodium molybdate dihydrate
7631-95-0

sodium molybdate dihydrate

water
7732-18-5

water

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

3Na(1+)*Mo154O462H14(H2O)48(H(O2CC(NH3)HCH2S)2)11(3-)*250H2O=Na3[Mo154O462H14(H2O)48(H(O2CC(NH3)HCH2S)2)11]*250H2O

3Na(1+)*Mo154O462H14(H2O)48(H(O2CC(NH3)HCH2S)2)11(3-)*250H2O=Na3[Mo154O462H14(H2O)48(H(O2CC(NH3)HCH2S)2)11]*250H2O

Conditions
ConditionsYield
In water stirred at room temp. for 5 min, heated at 55°C for 2 h (stirring), kept for 2 h at 20°C; filtered, standed for 2 d at 15-20°C, crysts. filtered, washed (cold water), dried (room temp.); elem. anal., TGA;37%
ammonium tetrathiotungstate
13862-78-7

ammonium tetrathiotungstate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

potassium di-μ-sulfido-bis{(cysteinato)oxotungstate(V)}

potassium di-μ-sulfido-bis{(cysteinato)oxotungstate(V)}

Conditions
ConditionsYield
With HCl; KOH; KCl In water concd. HCl is added to aq. soln. of W-compd., cysteine compd. is added, pH is adjusted to 7 (KOH), soln. is heated for 20 min, cooled to room temp. and filtered, KCl is added to the filtrate; soln. is kept in refrigerator overnight, crystals are filtered off, washed with MeOH and Et2O and recrystd. from hot H2O, elem. anal.;35%
sodium tungstate (VI) dihydrate
10213-10-2

sodium tungstate (VI) dihydrate

sodiumsulfide nonahydrate

sodiumsulfide nonahydrate

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

potassium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} pentahydrate

potassium (di-μ-sulfido)bis{(L-cysteinato)oxotungstate(V)} pentahydrate

Conditions
ConditionsYield
With HCl; KOH In water slow addn. of concd. HCl to aq. soln. of Na2WO4 and Na2S; addn. of L-cysteine; adjusting to pH 7 (KOH); heating at 50-70°C, 20 min; filtration; addn. of KCl; filtration; washing (methanol); recrystn. by dissoln. in hot water; filtration; addn. of KCl; allowing to stand overnight in a refrigerato; crystn.; elem. anal.;35%
sodium hydrogen selenide

sodium hydrogen selenide

ammonium heptamolybdate tetrahydrate

ammonium heptamolybdate tetrahydrate

cesium chloride

cesium chloride

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

2Cs(1+)*{Mo2O2Se2(O2CCH(NH2)CH2S)2}(2-)*4H2O=Cs2{Mo2O2Se2(O2CCH(NH2)CH2S)2}*4H2O

2Cs(1+)*{Mo2O2Se2(O2CCH(NH2)CH2S)2}(2-)*4H2O=Cs2{Mo2O2Se2(O2CCH(NH2)CH2S)2}*4H2O

Conditions
ConditionsYield
In water slow addn. of freshly prepd. NaHSe in H2O to aq. soln. of (NH4)6(Mo7O24)*6H2O; stirring for 24 h; filtering, addn. of HO2CCH(NH2)CH2SH in H2O (pH adjusted to 6 with NaOH); standing for 24 h at room temp., refiltering;; pptn. on addn. of CsCl in H2O; recrystn. from hot H2O; elem. anal.;;33.7%
tetrabutylammonium [(99g)Tc]tetrachlorooxotechnetate(V)

tetrabutylammonium [(99g)Tc]tetrachlorooxotechnetate(V)

L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

barium(II) chloride

barium(II) chloride

Ba(2+)*2(99)TcO(NH2CH(CH2S)CO2)2(1-)=Ba[(99)TcO(NH2CH(CH2S)CO2)2]2

Ba(2+)*2(99)TcO(NH2CH(CH2S)CO2)2(1-)=Ba[(99)TcO(NH2CH(CH2S)CO2)2]2

Conditions
ConditionsYield
With AcONH4 In methanol; water slow addn. of aq. cysteine to Tc-complex (in MeOH), pH-adjustment to 7.4(AcONH4), chromy. (celulose, MeOH; then Sephadex LH-20), concn., BaCl2 addn. (pptn.); recrystn. (50% aq. MeOH); elem. anal.;33%
L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

2-Bromoacetyl bromide
598-21-0

2-Bromoacetyl bromide

(R)-5-oxothiomorpholine-3-carboxylic acid
62305-89-9

(R)-5-oxothiomorpholine-3-carboxylic acid

Conditions
ConditionsYield
With sodium carbonate In water for 12h; Ambient temperature;15%
L-cysteine hydrochloride monohydrate
7048-04-6

L-cysteine hydrochloride monohydrate

formamidine disulfide dihydrochloride (1 mol)

formamidine disulfide dihydrochloride (1 mol)

S-guanylsulfanyl-L-cysteine
89838-59-5

S-guanylsulfanyl-L-cysteine

L-Cysteine hydrochloride monohydrate Chemical Properties

L-Cysteine hydrochloride monohydratewhite is crystals or crystalline powder with strongly acid taste. L-Cysteine hydrochloride monohydratewhite is very soluble in water.
appearance: white solid.
formula: C3H7NO2S.HCl.H2O.
molecular weight: 175.64 g/mol.
melting point: 176°C.
solubility: soluble in cold water.

L-Cysteine hydrochloride monohydrate Uses

L-Cysteine Hydrochloride Monohydrate is widely used in fields of medicine, food processing, biological study, materials of chemical industry and so on.
It's used as raw materials for manufacturing N-Acetyl-L-Cysteine, S-Carboxymethyl
-L-Cysteine and L-Cysteine base etc.
Besides, it is useful to cure liver disease, antioxidant and antidote. 
In addition, it is used in cosmetic.

L-Cysteine hydrochloride monohydrate Toxicity Data With Reference

ORAL (LD50): Acute: 3550 mg/kg [Mouse]. 5580 mg/kg[Rat]. 4200 mg/kg [Mouse].
It is very hazardous in case of skin and eye contact, of ingestion, of inhalation.
Repeated or prolonged inhalation of it may lead to chronic respiratory irritation.

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