TRIFLUOROMETHYL HYPOFLUORITE supplier

Name
TRIFLUOROMETHYLHYPOFLUORITE
EINECS
CAS No. 373-91-1
Article Data48
CAS DataBase
Density 1.419g/cm³
Solubility
Melting Point -213°C
Formula CF4 O
Boiling Point -95°C
Molecular Weight 104.004
Flash Point °C
Transport Information
Appearance
Safety A powerful oxidant. Explodes on contact with acetylene, cyclopropane, ethylene, hydrogen-containing solvents, polymers, and rubber. Solutions in benzene are spark- and UV light-sensitive explosives. Reacts with pyridine to form an explosive product. When heated to decomposition it emits toxic fumes of F⁻. See also FLUORIDES and HYPOCHLORITES.
Risk Codes 8-23-34
Molecular Structure
Hazard Symbols
Synonyms Methanol,trifluoro-, hypofluorite (6CI,7CI,8CI); Carbon fluoride oxide (CF4O);Fluorooxyperfluoromethane; Fluorooxytrifluoromethane; Fluoroxytrifluoromethane;Trifluoro(fluorooxy)methane; Trifluorofluoroxymethane; Trifluoromethylhypofluorite; Trifluoromethyl hypofluorite (CF3OF)
PSA 9.23000
LogP 1.40730

Synthetic route

: 353-50-4
Carbonyl fluoride

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
copper; cesium fluoride at 100℃;	98%
With fluorine; copper; cesium fluoride at 100℃; Gas phase;	98%
With fluorine; cesium fluoride at -196 - 22℃; for 5h; stainless steel cylinder;

: 353-50-4
Carbonyl fluoride

: 7782-41-4
fluorine

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
rubidium fluoride equimolar amt. of educts, steel vessel, -78°C, yield: 97 mol-%;	97%
potassium fluoride equimolar amt. of educts, steel vessel, -78°C, yield: 97 mol-%;	97%
cesium fluoride equimolar amt. of educts, steel vessel, -78°C, yield: 97 mol-%;	97%

: 353-50-4
Carbonyl fluoride

: 7782-41-4
fluorine

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 927-84-4
bis(trifluoromethyl)peroxide

Conditions

Conditions	Yield
yttrium(III) fluoride Kinetics; 150°C, 10 h;	A n/a B 95%
bismuth(III) fluoride Kinetics; 150°C, 12 h;	A n/a B 95%
terbium(III) fluoride Kinetics; 100°C, 30 h;	A n/a B 95%

...Expand

: 75-44-5
phosgene

: 7664-39-3
hydrogen fluoride

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 353-50-4
Carbonyl fluoride

D: 75-72-9
chlorotrifluoromethane

E: 7782-50-5
chlorine

Conditions

Conditions	Yield
Electrochem. Process; water free HF, COCl2 dild. with He, 12-13°C, 7-8 V, current density: 1.7 A/dm2, electrolysis;	A 10% B 8% C 82% D <1 E <1

...Expand

: 201230-82-2
carbon monoxide

: 7782-41-4
fluorine

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
silver(II) fluoride 160 to 180°C, in flow;	70%

: 124-38-9
carbon dioxide

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 353-50-4
Carbonyl fluoride

Conditions

Conditions	Yield
With fluorine at 224.84℃; under 1140.11 Torr; for 50h;	A 51.5% B 1.5% C 6%
With fluorine at 224.84℃; under 1140.11 Torr; for 72h;	A 32.1% B 4.6% C 11.1%

...Expand

: 67-56-1
methanol

: 353-50-4
Carbonyl fluoride

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
With silver(II) fluoride; copper; fluorine at 160 - 180℃;

: 75-63-8
Bromotrifluoromethane

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 353-50-4
Carbonyl fluoride

C: 753-56-0
carbonyl bromide fluoride

D: 75-46-7
trifluoromethan

E: 1493-11-4
trifluoromethanol

Conditions

Conditions	Yield
With hydrogen; oxygen at 469℃; under 500 Torr; Thermodynamic data; Product distribution; E(act); further reaction times,;

...Expand

: 21811-29-0
trifluoroketone

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
With F at 26.9℃; Rate constant; Irradiation;

: 201230-82-2
carbon monoxide

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
With fluorine; cesium fluoride	66.0 g
With fluorine Heating;
With aluminum oxide; nickel(II) fluoride; fluorine Heating;

: 2923-18-4
sodium 2,2,2-trifluoroacetate

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 16282-67-0
bis(fluoroxy)difluoromethane

C: 3848-94-0
pentafluoroethyl oxyfluoride

D: 16329-92-3
1,1-Difluoroxy-1,2,2,2-tetrafluorethan

Conditions

Conditions	Yield
With fluorine at 0℃; Title compound not separated from byproducts;	A 60 % Spectr. B 5 % Spectr. C 28 % Spectr. D 7 % Spectr.
With fluorine at 0℃; Title compound not separated from byproducts;	A 29.5 % Spectr. B 5.4 % Spectr. C 40.5 % Spectr. D 24.6 % Spectr.
With fluorine at 0℃; Title compound not separated from byproducts;	A 29.5 % Spectr. B 5.4 % Spectr. C 40 % Spectr. D 24.6 % Spectr.
With fluorine at 0℃; Product distribution; Mechanism; var. temperature;

...Expand

: 359-63-7
N,N-bis(trifluoromethyl)hydroxylamine

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 334-99-6
trifluoronitrosomethane

C: 335-01-3
difluoramino trifluoromethane

D: 359-62-6
fluoro-bis-trifluoromethyl-amine

Conditions

Conditions	Yield
With fluorine; cesium fluoride In trichlorofluoromethane at -78℃; for 24h; Fluorination; Further byproducts given;

...Expand

: 67-56-1
methanol

fluorine: fluorine

nitrogen: nitrogen

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
at 160 - 180℃; Leiten ueber AgF2 auf Kupfer;

...Expand

: 67-56-1
methanol

CO: CO

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
With silver(II) fluoride; copper; fluorine at 160 - 180℃;

: 75-63-8
Bromotrifluoromethane

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 353-50-4
Carbonyl fluoride

D CO2: CO2

Conditions

Conditions	Yield
With carbon dioxide; oxygen at 500 - 800℃; Kinetics; Mechanism;

...Expand

: fluorooxydifluoromethyl hydroperoxide

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 16282-67-0
bis(fluoroxy)difluoromethane

C: 17700-20-8
Bis-(difluor-fluoroxy-methyl)-peroxid

D: CF4O3

Conditions

Conditions	Yield
With potassium hydrogen bifluoride; fluorine at -196 - -78℃; for 6h;

...Expand

: 353-50-4
Carbonyl fluoride

: sodium fluoride

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 927-84-4
bis(trifluoromethyl)peroxide

Conditions

Conditions	Yield
In hydrogen fluoride Electrochem. Process; solvent: anhydrous HF, 7-8°C, dild. with He, total yield: 74 %,;

...Expand

: 7664-39-3
hydrogen fluoride

: sodium fluoride

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 353-50-4
Carbonyl fluoride

D: 1479-49-8
bis(trifluoromethyl) ether

E: 927-84-4
bis(trifluoromethyl)peroxide

Conditions

Conditions	Yield
byproducts: CO, CO2; Electrolysis; anhyd. HF, 7-8°C, 5.5-6 V, anodic current density: 2.2 A/dm2, gas mixture contains 40 vol.-% He,;	A n/a B n/a C n/a D <1 E n/a

...Expand

: 353-50-4
Carbonyl fluoride

: 13400-13-0
cesium fluoride

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
In further solvent(s) solvent: CH3CN soln., -78°C;	>99

: 353-50-4
Carbonyl fluoride

: 7782-41-4
fluorine

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 75-73-0
carbon tetrafluoride

C: 927-84-4
bis(trifluoromethyl)peroxide

Conditions

Conditions	Yield
Kinetics; Irradiation (UV/VIS); photochemical react., molar ratio of COF2:F2=1:2-3, total pressure < 1 atm, quartz vessel, 35°C, Hg-vapour lamp;	A n/a B <1 C n/a

...Expand

: 590-28-3
potassium cyanate

: 7782-41-4
fluorine

A: 7783-54-2
nitrogen trifluoride

B: 373-91-1
hypofluorous acid trifluoromethyl ester

C: 353-50-4
Carbonyl fluoride

Conditions

Conditions	Yield
fluoronation;

...Expand

: 201230-82-2
carbon monoxide

: 7782-41-4
fluorine

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 353-50-4
Carbonyl fluoride

C: 927-84-4
bis(trifluoromethyl)peroxide

Conditions

Conditions	Yield
copper 25-200°C, yield given at 25°C, Cu covered with Ag-fluoride, when it covered with CsF, no catalytic effect;	A n/a B >95 C n/a

...Expand

: 354-38-1
2,2,2-trifluoroacetamide

: 80937-33-3
oxygen

: 7782-41-4
fluorine

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 353-50-4
Carbonyl fluoride

Conditions

Conditions	Yield
byproducts: NF3,HF; At -6°C.;
byproducts: NF3,HF; At -6°C.;

...Expand

: 16847-33-9
K(1+)*OCF2NF2(1-)=KOCF2NF2

: 7782-41-4
fluorine

: 373-91-1
hypofluorous acid trifluoromethyl ester

Conditions

Conditions	Yield
In acetonitrile byproducts: NF3; at -40°C;
byproducts: NF3; at -184°C;
In acetonitrile byproducts: NF3; at -40°C;
byproducts: NF3; at -184°C;

: 3855-41-2
fluoroformyliminosulfur difluoride

A: 7783-54-2
nitrogen trifluoride

B: 373-91-1
hypofluorous acid trifluoromethyl ester

C: 353-50-4
Carbonyl fluoride

D: 7783-60-0
sulfur tetrafluoride

Conditions

Conditions	Yield
Electrochem. Process; electrochemical fluorination;
Electrochem. Process; electrochemical fluorination;

...Expand

: 201230-82-2
carbon monoxide

A: 373-91-1
hypofluorous acid trifluoromethyl ester

B: 353-50-4
Carbonyl fluoride

Conditions

Conditions	Yield
With fluorine at -18℃; Gas phase; Flow reactor;

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 2,2,3,3-tetramethyl-1-(benzenesulfonyl)aziridine

: C13H17F4NO3S

Conditions

Conditions	Yield
In trichlorofluoromethane at 0℃; Mechanism; homologs also investigated;	100%
In trichlorofluoromethane at 0℃;	100%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 374-10-7
trifluoro(trifluoromethyl)sulfur(IV)

Conditions

Conditions	Yield
at -78°C, 0.5 h;	100%
at -78°C, 0.5 h;	100%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 201230-82-2
carbon monoxide

: 3299-24-9
Fluorameisensaeure-perfluormethylester

Conditions

Conditions	Yield
at 170℃; for 4h; Reactor;	99.8%
With fluorine at 20℃; for 48h;	18.4%

: 127-18-4
1,1,2,2-tetrachloroethylene

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 136649-69-9
1,1,2,2-tetrachloro-1-fluoro-2-trifluoromethoxyethane

Conditions

Conditions	Yield
at 40.6℃;	99.5%
at 160 - 195℃; under 750.075 Torr; for 31h;	84.3%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 598-88-9
1,2-dichloro-1,2-difluoroethene

: 2356-53-8
1-trifluoromethoxy-1,2-dichlorotrifluoroethane

Conditions

Conditions	Yield
In trichlorofluoromethane at -70℃; for 0.166667 - 4h; Product distribution / selectivity;	98.4%
In CFCl3 at -70℃; for 0.166667 - 4h; Product distribution / selectivity;	98.4%
at -70℃; Inert atmosphere; Flow reactor;	97%
at 140 - 170℃; under 5250.53 Torr; for 190h;	87.23%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 371-71-1
Perfluoro-2-azapropen

: 432-00-8
bis(trifluoromethyl)carbamoyl fluoride

Conditions

Conditions	Yield
With cesium fluoride at -75 - 25℃; for 24h; Addition;	95%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 75-63-8
Bromotrifluoromethane

A: 353-50-4
Carbonyl fluoride

B: 753-56-0
carbonyl bromide fluoride

C: 38126-07-7
difluorobromoacetyl fluoride

Conditions

Conditions	Yield
With oxygen at -0.15℃; for 0.166667h; gas-phase;	A n/a B n/a C 95%

...Expand

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 201230-82-2
carbon monoxide

: 2070-70-4
perfluoro-4-methyl-2-pentene

A: 5659-86-9
bis(trifluoro)methyl carbonate

B: 3299-24-9
Fluorameisensaeure-perfluormethylester

C: perfluoro-3-methoxy-2-methylpentane

D: 1,1,1,2,3,3,4,5,5,5-Decafluoro-2-trifluoromethoxy-4-trifluoromethyl-pentane

Conditions

Conditions	Yield
at -196 - 51℃; Reactor;	A n/a B 91.4% C n/a D n/a

...Expand

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 79-01-6
Trichloroethylene

: 94720-90-8
1-fluoro-2-trifluoromethyl-1,1,2-trichloroethane

Conditions

Conditions	Yield
at 120 - 150℃; under 1725.17 Torr; for 24h;	88.54%

: 21384-47-4
(2-methylaziridin-1-yl)(4-nitrophenyl)methanone

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 74953-35-8
p-nitrobenzoate de trifluoromethyle

Conditions

Conditions	Yield
In trichlorofluoromethane at -40℃;	87%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 1605-06-7, 855419-50-0
cis-2,3-diphenylaziridine

A: 69393-90-4
bis(cisdiphenyl-2,3 aziridine)-1,1' carbonyle

B: (2R,3S)-1-Fluoro-2,3-diphenyl-aziridine

C: fluorure de (diphenyl-2,3 aziridine)-1 carbonyle

Conditions

Conditions	Yield
In trichlorofluoromethane at -40℃;	A n/a B 5 % Spectr. C 87%

...Expand

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 201230-82-2
carbon monoxide

: 2070-70-4
perfluoro-4-methyl-2-pentene

A: 3299-24-9
Fluorameisensaeure-perfluormethylester

B: perfluoro-3-methoxy-2-methylpentane

C: 1,1,1,2,3,3,4,5,5,5-Decafluoro-2-trifluoromethoxy-4-trifluoromethyl-pentane

Conditions

Conditions	Yield
at -196 - 40℃; Reactor;	A 85.7% B n/a C n/a

...Expand

: 127-18-4
1,1,2,2-tetrachloroethylene

: 373-91-1
hypofluorous acid trifluoromethyl ester

A: 76-12-0
CFC-112a

B: 354-17-6
dichloro-fluoro-acetyl chloride

C: 136649-69-9
1,1,2,2-tetrachloro-1-fluoro-2-trifluoromethoxyethane

D: 76-02-8
Trichloroacetyl chloride

E: Dichloro-trifluoromethoxy-acetyl chloride

F COCl2: COCl2

Conditions

Conditions	Yield
With oxygen at 40.9℃; under 420.8 Torr; for 1.97833h; Product distribution; Mechanism; Rate constant; var. of partial pressure, temp.;	A n/a B n/a C n/a D 85% E n/a F n/a

...Expand

: 75580-94-8
β-ethoxy-4-isobutyl-α-methyl-β-(trimethylsiloxy)-styrene

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 74590-67-3
ethyl 2-fluoro-2-(4-isobutylphenyl)propanoate

Conditions

Conditions	Yield
In CFCl3	85%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 74-85-1
ethene

: 819-49-8
Trifluoromethyl 2-fluoroethyl ether

Conditions

Conditions	Yield
for 20h; -111 deg C to 20 deg C;	83%
under 280 Torr; UV-Licht.Irradiation;
With nitrogen Irradiation.mit UV-Licht;

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 75-38-7
Vinylidene fluoride

: 20193-67-3
2,2,2-trifluoroethyl trifluoromethyl ether

Conditions

Conditions	Yield
for 20h; -111 deg C to 20 deg C;	83%
Product distribution / selectivity;

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 1605-06-7, 855419-50-0
cis-2,3-diphenylaziridine

: 69393-90-4
bis(cisdiphenyl-2,3 aziridine)-1,1' carbonyle

Conditions

Conditions	Yield
In trichlorofluoromethane	83%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 31491-20-0
(1-ethoxy-2-phenylvinyloxy)trimethylsilane

: 643-77-6
fluoro-phenyl-acetic acid ethyl ester

Conditions

Conditions	Yield
In CFCl3	77%

: 2658-24-4
2,2-dimethylaziridine

: 373-91-1
hypofluorous acid trifluoromethyl ester

: fluorure de (dimethyl-2,2 aziridine)-1 carbonyle

Conditions

Conditions	Yield
In trichlorofluoromethane at -40℃;	76%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 75-38-7
Vinylidene fluoride

A: 20193-67-3
2,2,2-trifluoroethyl trifluoromethyl ether

B: 84011-00-7
1,1,2-trifluoro-1-(trifluoromethoxy)ethane

Conditions

Conditions	Yield
In trichlorofluoromethane at -160 - 22℃; for 20h; Yields of byproduct given. Title compound not separated from byproducts;	A 76% B n/a
In trichlorofluoromethane at -160 - 22℃; for 20h; Product distribution; various temperatures, olefins, solvents and times;	A 97.5 % Spectr. B 2 % Spectr.

...Expand

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 93-76-5
2,4,5-Trichlorophenoxyacetic acid

: 74590-71-9
2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid

Conditions

Conditions	Yield
With n-butyllithium; chloro-trimethyl-silane; diisopropylamine In tetrahydrofuran; hexane; trichlorofluoromethane; water	76%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 75-35-4
1,1-Dichloroethylene

: 84010-99-1
1,1-Dichloro-1-fluoro-2-trifluoromethoxy-ethane

Conditions

Conditions	Yield
In trichlorofluoromethane at -150 - 22℃; for 20h;	75%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 88089-52-5
(Z)-((1,2-diphenylvinyl)oxy)trimethylsilane

: 720-43-4
2-fluoro-1,2-diphenylethanone

Conditions

Conditions	Yield
In chlorotrifluoromethane	72%

: 116-14-3
polytetrafluoroethylene

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 665-16-7
pentafluoroethyl trifluoromethyl ether

Conditions

Conditions	Yield
Stage #1: polytetrafluoroethylene at -90℃; for 0.5h; Inert atmosphere; Stage #2: hypofluorous acid trifluoromethyl ester With potassium hydroxide at -85℃; under 760.051 Torr; for 2h; Temperature; Inert atmosphere;	71.9%
With PFPE Galden(R) LS155 for 1h;

: 373-91-1
hypofluorous acid trifluoromethyl ester

: chloro-1 tetramethyl-2,2,3,3 aziridine

: N-chloro-N-fluoro-dimethyl-2,3 trifluoromethoxy-3 butylamine-2

Conditions

Conditions	Yield
In trichlorofluoromethane at -40℃;	71%

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 57527-54-5
1-<(benzylidene)amino>adamantane

: 52072-75-0
1-difluoroaminoadamantane

Conditions

Conditions	Yield
In hexane; chloroform	71%

TRIFLUOROMETHYL HYPOFLUORITE Chemical Properties

Product Name: Trifluoromethyl hypofluorite (CAS NO.373-91-1)

Molecular Formula: CF₄O
Molecular Weight: 104g/mol
Mol File: 373-91-1.mol
Einecs: 206-772-7
Melting Point: -213°C
Boiling point: -95°C
Density: 1.419 g/cm³
Surface Tension: 8.4 dyne/cm
Enthalpy of Vaporization: 19.76 kJ/mol
Vapour Pressure: 9460 mmHg at 25°C
XLogP3-AA: 1.8
H-Bond Donor: 0
H-Bond Acceptor: 5

TRIFLUOROMETHYL HYPOFLUORITE Safety Profile

A powerful oxidant. Explodes on contact with acetylene, cyclopropane, ethylene, hydrogen-containing solvents, polymers, and rubber. Solutions in benzene are spark- and UV light-sensitive explosives. Reacts with pyridine to form an explosive product. When heated to decomposition it emits toxic fumes of F⁻. See also FLUORIDES and HYPOCHLORITES.
Safety Information of Trifluoromethyl hypofluorite (CAS NO.373-91-1):
Risk Statements: 8-23-34
8: Contact with combustible material may cause fire
23: Toxic by inhalation
34: Causes burns
Safety Statements: 17-26-38-45
17: Keep away from combustible material
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
38: In case of insufficient ventilation, wear suitable respiratory equipment
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

TRIFLUOROMETHYL HYPOFLUORITE Specification

Trifluoromethyl hypofluorite ,its CAS NO. is 373-91-1,the synonyms is Hypofluorous acid, trifluoromethyl ester ; (Trifluoromethoxy) fluoride ; Trifluoro(fluorooxy)methane ; Trifluoromethoxy fluoride .

Product Name

TRIFLUOROMETHYLHYPOFLUORITE

Synthetic route

TRIFLUOROMETHYL HYPOFLUORITE Chemical Properties

TRIFLUOROMETHYL HYPOFLUORITE Safety Profile

TRIFLUOROMETHYL HYPOFLUORITE Specification

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