Trimethoxysilane supplier | CasNO.2487-90-3

Name
Trimethoxysilane
EINECS 219-637-2
CAS No. 2487-90-3
Article Data43
CAS DataBase
Density 0.96 g/cm³
Solubility
Melting Point -115 °C(lit.)
Formula C₃H₁₀O₃Si
Boiling Point 81 °C at 760 mmHg
Molecular Weight 122.196
Flash Point 24 °F
Transport Information UN 3384 6.1/PG 1
Appearance colorless transparent liquid
Safety 16-36/37/39-45
Risk Codes 11-26-36
Molecular Structure
Hazard Symbols F,T+
Synonyms LS330;Trimethoxysilan;
PSA 27.69000
LogP -0.35720

Synthetic route

: 67-56-1
methanol

: 2487-90-3
trimethoxysilane

Conditions

Conditions	Yield
With copper(II) nitrate trihydrate; cetyltrimethylammonim bromide; hydrazine hydrate; silicon at 220 - 260℃; under 760.051 Torr; for 1h; Microwave irradiation;	96.9%
With trichlorosilane at 100℃; for 6h; Temperature;	82.6%
With amorphous silicon In paraffin oil at 230℃; for 5h; Inert atmosphere; Schlenk technique;	33%

: 10025-78-2
trichlorosilane

: 2487-90-3
trimethoxysilane

Conditions

Conditions	Yield
With methanol	66%
With CH3OH	66%

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

Conditions

Conditions	Yield
With amorphous silicon In paraffin oil at 300℃; for 6h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique;	A 24% B 21%
With copper; silicon at 259.9℃; under 742.6 Torr; for 5h; Product distribution; preheating at 623 K for 3 h; other reaction times, temperatures, and partial pressures;
With copper(l) chloride; silicon at 219.9℃; under 442.5 Torr; Kinetics; temperature- and pressure dependence;

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 5314-52-3
dimethoxysilane

D: 16881-77-9
(dimethoxy)methylsilane

Conditions

Conditions	Yield
With thiophene; silicon grains; copper(l) chloride at 379.85℃; under 315.025 Torr;	A n/a B n/a C n/a D 10%
With thiophene; silicon grains; copper(l) chloride at 379.85 - 449.85℃; under 315.025 Torr; for 3h;

...Expand

: 67-56-1
methanol

: 1471-03-0
allyl propyl ether

A: 2487-90-3
trimethoxysilane

B: 18147-35-8
allyltrimethoxysilane

C: C5H14O3Si

Conditions

Conditions	Yield
With copper(l) chloride; silicon at 239.9℃; Mechanism; also with allyl ethyl ether and allyl methyl sulfide;

...Expand

: 67-56-1
methanol

: 74-85-1
ethene

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 5314-55-6
ethyltrimethoxysilane

D: 19753-84-5
ethyl dimethoxy silane

Conditions

Conditions	Yield
With copper(l) chloride; silicon In toluene at 159.9℃; under 3040 Torr; for 3h; Product distribution; Mechanism; also ethanol; other solvents; effect of the amount of methanol on the silicon conversion and selectivity for organomethoxysilanes; var. pressures, times and temperatures;

...Expand

: 67-56-1
methanol

silane: silane

copper: copper

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 5314-52-3
dimethoxysilane

...Expand

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B dimethoxysilane and tetramethyl silicate: dimethoxysilane and tetramethyl silicate

Conditions

Conditions	Yield
With copper; monosilane

H3 BO3: H3 BO3

NaOCH3 powder: NaOCH3 powder

: 124-41-4
sodium methylate

: 11113-50-1
boric acid

: 7440-21-3
silicon

: 2487-90-3
trimethoxysilane

...Expand

: 67-56-1
methanol

: 7440-21-3
silicon

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1112-39-6
dimethyldimethoxysilan

Conditions

Conditions	Yield
With sodium chloride at 150℃; Product distribution / selectivity;
With sodium chloride; copper(I) oxide at 150℃; Product distribution / selectivity;

...Expand

: 67-56-1
methanol

: 7440-21-3
silicon

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1112-39-6
dimethyldimethoxysilan

D: 1185-55-3
Methyltrimethoxysilan

Conditions

Conditions	Yield
With sodium chloride at 150 - 200℃; Product distribution / selectivity;
With sodium chloride; copper(l) chloride at 150℃; Product distribution / selectivity;

...Expand

: 67-56-1
methanol

silicon, oxidized: silicon, oxidized

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1112-39-6
dimethyldimethoxysilan

D: 1185-55-3
Methyltrimethoxysilan

Conditions

Conditions	Yield
With sodium chloride; copper(l) chloride at 150 - 320℃; Product distribution / selectivity;

...Expand

: 681-84-5
tetramethylorthosilicate

: 2487-90-3
trimethoxysilane

: 67-56-1
methanol

: 7440-21-3
silicon

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

Conditions

Conditions	Yield
copper(II) hydroxide In THERMINOL 59 at 250℃; Product distribution / selectivity;
basic copper phosphate In THERMINOL 59 at 250℃; Product distribution / selectivity;
copper(II) dimetaphosphate In THERMINOL 59 at 250℃; Product distribution / selectivity;
In THERMINOL 59 at 250℃; Product distribution / selectivity;
With FS1265; copper(II) hydroxide In THERMINOL 59 at 250℃; for 14.78h; Product distribution / selectivity;

...Expand

: 67-56-1
methanol

: 7440-21-3
silicon

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1185-55-3
Methyltrimethoxysilan

D: 16881-77-9
(dimethoxy)methylsilane

Conditions

Conditions	Yield
copper(II) orthophosphate In THERMINOL 59 at 250℃; Product distribution / selectivity;
copper(II) hydroxide; sodium phosphate In THERMINOL 59 at 250℃; Product distribution / selectivity;
copper(II) orthophosphate; copper(II) hydroxide In THERMINOL 59 at 250℃; Product distribution / selectivity;

...Expand

: 67-56-1
methanol

: 7440-21-3
silicon

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 16881-77-9
(dimethoxy)methylsilane

Conditions

Conditions	Yield
copper(II) hydroxide In THERMINOL 59 at 250℃; Product distribution / selectivity;

...Expand

: 127973-36-8
hydro-N,N',N''-tris(dimethylboryl)azasilatrane

A: 2487-90-3
trimethoxysilane

B: tris{2-((dimethylboryl)amino)ethyl}amine

Conditions

Conditions	Yield
With methanol In chloroform-d1 Ar-atmosphere; not isolated, reaction followed by NMR spectroscopy;

: 67-56-1
methanol

: 7440-21-3
silicon

: 2487-90-3
trimethoxysilane

Conditions

Conditions	Yield
copper(l) chloride In Marlotherm SH at 180 - 190℃; for 3.48333h; Product distribution / selectivity; Microwave irradiation;

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 4861-14-7
chlorodimethoxysilane

Conditions

Conditions	Yield
With trichlorosilane In hexane at 0℃; Inert atmosphere;

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1185-55-3
Methyltrimethoxysilan

Conditions

Conditions	Yield
With amorphous silicon at 200℃; Temperature; Inert atmosphere; Schlenk technique;

...Expand

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1112-39-6
dimethyldimethoxysilan

D: 1185-55-3
Methyltrimethoxysilan

Conditions

Conditions	Yield
With amorphous silicon In paraffin oil at -196 - 150℃; Reagent/catalyst; Sealed tube; Inert atmosphere; Schlenk technique;

...Expand

: 67-56-1
methanol

A: 2487-90-3
trimethoxysilane

B: 681-84-5
tetramethylorthosilicate

C: 1112-39-6
dimethyldimethoxysilan

Conditions

Conditions	Yield
With amorphous silicon at 150℃; Sealed tube; Inert atmosphere; Schlenk technique;

...Expand

: 592-41-6
1-hexene

: 2487-90-3
trimethoxysilane

: 3069-19-0
n-hexyltrimethoxysilane

Conditions

Conditions	Yield
at 90℃; for 5h; Inert atmosphere;	100%
at 90℃; for 5h; Inert atmosphere;	100%
With dichlorobis-(ethylene)-μ,μ'-dichloroplatinum(II)

: 2487-90-3
trimethoxysilane

: 324047-51-0
1,2,3,4-tetra-O-acetyl-6-O-[4-(10-undecenyloxy)benzoyl]-β-D-glucose

: C35H54O15Si

Conditions

Conditions	Yield
With dihydrogen hexachloroplatinate In toluene at 42℃; for 15h;	100%

: 146763-69-1
propanedioic acid, [[4-(2-propynyloxy)phenyl]methylene]diethyl ester

: 2487-90-3
trimethoxysilane

: 2-[4-[2-(trimethoxysilyl)prop-2-enyloxy]benzylidene]-malonic acid diethyl ester

Conditions

Conditions	Yield
platinum 1,3-divinyl-1,1,3,3-tetramethyldisiloxane In toluene at 70℃; for 2h;	100%

: {Ru2(CO)(MeCN)(μ-CH2)(μ-CO)(η-C5H5)2}

: 2487-90-3
trimethoxysilane

: (C5H5)2Ru2(μ-CH2)(H)(Si(OMe)3)(CO)2

Conditions

Conditions	Yield
In benzene inert atmosphere; evapn. (reduced pressure); detd. by NMR spectroscopy;	100%

: 2487-90-3
trimethoxysilane

: 23354-88-3
1,4-bis-(5-bromothiophen-2-yl)benzene

: 1379804-24-6
1,4-di(5-trimethoxysilylthien-2-yl)benzene

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 65℃; for 2h; Inert atmosphere;	100%

: 75070-85-8
rhodium hydrido (PEt3)3 complex

: 2487-90-3
trimethoxysilane

: 949116-20-5
[Rh{Si(OEt)3}(PEt3)3]

Conditions

Conditions	Yield
In benzene-d6 Schlenk technique; Inert atmosphere;	100%

: 2487-90-3
trimethoxysilane

: 1055315-90-6
[Rh(CH3)(triethylphosphine)3]

: 1446417-56-6
[Rh{Si(OEt)3}(PEt3)3]

Conditions

Conditions	Yield
In pentane at -90.16℃; Schlenk technique; Inert atmosphere;	100%

: 2487-90-3
trimethoxysilane

: 1609376-04-6
2-bromo-5-(t-butyl)-1,3-bis[bis(trimethylsilyl)methyl]benzene

: C26H56O2Si5

Conditions

Conditions	Yield
Stage #1: 2-bromo-5-(t-butyl)-1,3-bis[bis(trimethylsilyl)methyl]benzene With tert.-butyl lithium In pentane at -75℃; for 1h; Inert atmosphere; Stage #2: trimethoxysilane In pentane at -75 - 20℃; Inert atmosphere;	100%

: 2487-90-3
trimethoxysilane

: C25H48N2O3

: C28H58N2O6Si

Conditions

Conditions	Yield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 65℃; for 20h;	100%

: triethyleneglycol-monomethyl-monoallyl ether

: 2487-90-3
trimethoxysilane

A 3-methyltri.lgycol-oxypropylsilane-trimethyl ester: 3-methyltri.lgycol-oxypropylsilane-trimethyl ester

B: triethyleneglycol-monomethylmonopropenyl ether

Conditions

Conditions	Yield
	A 99.4% B n/a

...Expand

: 2487-90-3
trimethoxysilane

: 101268-55-7
4,4-bis(ethoxycarbonyl)-1-hepten-6-yne

: 4,4-bis(carbethoxy)-1-(Z)-trimethoxysilylmethylidene-2-methylcyclopentane

Conditions

Conditions	Yield
With carbon monoxide; dodecacarbonyltetrarhodium(0) In hexane at 20℃; under 760.051 Torr; for 0.0833333h;	99%

: 2487-90-3
trimethoxysilane

: [Ru((H2CCH(CH2)3C5H3N)2)3](2+)*2Cl(1-)=[Ru((H2CCH(CH2)3C5H3N)2)3]Cl2

: [Ru(((CH3O)3Si(CH2)5C5H3N)2)3](2+)*2Cl(1-)=[Ru(((CH3O)3Si(CH2)5C5H3N)2)3]Cl2

Conditions

Conditions	Yield
With palladium on activated charcoal In not given	99%

: 2487-90-3
trimethoxysilane

: 1379804-12-2
4,4'-di(5-iodothien-2-yl)biphenyl

: 1379804-28-0
4,4'-di(5-trimethoxysilylthien-2-yl)biphenyl

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); johnphos In N,N-dimethyl-formamide at 80℃; for 0.5h; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: 1,4-bis(5-iodothiophen-2-yl)benzene

: 1379804-24-6
1,4-di(5-trimethoxysilylthien-2-yl)benzene

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); johnphos In N,N-dimethyl-formamide at 80℃; for 0.5h; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: 115160-05-9
1-bromo-2,4,6-tris[bis(trimethylsilyl)methyl]benzene

: 1450630-73-5
C29H66O2Si7

Conditions

Conditions	Yield
Stage #1: 1-bromo-2,4,6-tris[bis(trimethylsilyl)methyl]benzene With tert.-butyl lithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: trimethoxysilane In tetrahydrofuran at 20℃; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: C22H24F3N3O2

: C25H34F3N3O5Si

Conditions

Conditions	Yield
With dichloro(dicyclopentadienyl)platinum(II) In tetrahydrofuran at 60℃; for 24h;	99%

: 2487-90-3
trimethoxysilane

: C25H31N3O3

: C28H41N3O6Si

Conditions

Conditions	Yield
With (dcp)PtCl2 In toluene at 80℃; for 24h; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: C35H40N6O4

C38H50N6O7Si: C38H50N6O7Si

Conditions

Conditions	Yield
With (dcp)PtCl2 In toluene at 80℃; for 24h; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: 2754-32-7
1,4-bis(hydroxydimethylsilyl)benzene

: C14H30O6Si4

Conditions

Conditions	Yield
In toluene at 100℃; for 16h; Temperature; Solvent; Inert atmosphere;	99%

: 2487-90-3
trimethoxysilane

: 229162-26-9
1,3,4,6-tetraallyl glycoluril

: C28H62N4O14Si4

Conditions

Conditions	Yield
With platinum 1,3-divinyl-1,1,3,3-tetramethyldisiloxane; formamide In toluene at 60℃; for 2h;	98.84%

: 2487-90-3
trimethoxysilane

: 25291-17-2
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene

: (1H,1H,2H,2H-tridecafluorooctyl)trimethoxysilane

Conditions

Conditions	Yield
With chloroplatinic acid In isopropyl alcohol at 25℃; for 0.133333h;	98.2%

: 2487-90-3
trimethoxysilane

: 74-86-2
acetylene

: 2768-02-7
(vinyl)trimethoxylsilane

Conditions

Conditions	Yield
With acetylacetonatodicarbonylrhodium(l) at 20℃; for 1h;	98%
at 88℃; under 225.023 - 375.038 Torr; Temperature;	94.2%
dichlorotetraammine platinum; silica gel In various solvent(s) at 150℃; under 412.533 Torr;	67%
at 150℃;	51%
dihydrogen hexachloroplatinate at 120℃; under 1670.26 Torr; Product distribution / selectivity; Inert atmosphere;

: 2487-90-3
trimethoxysilane

: 16356-02-8
1,4-dimethoxy-2-butyne

: (E)-1,4-dimethoxy-2-trimethoxysilyl-2-buten

Conditions

Conditions	Yield
Rh(I)-catalyst In tetrahydrofuran for 2h; Ambient temperature;	98%

: 2487-90-3
trimethoxysilane

: 1379804-23-5
tris (4-(5-iodothiophen-2-yl)phenyl)amine

: 1379804-35-9
tri(4-(5-trimethoxysilylthien-2-yl)phenyl)amine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); johnphos In N,N-dimethyl-formamide at 80℃; for 0.5h; Inert atmosphere;	98%

: 2487-90-3
trimethoxysilane

: 1379804-09-7
5,5'-(2,5-dimethyl-1,4-phenylene)bis(2-iodothiophene)

: 1379804-25-7
2,5-di(5-trimethoxysilylthien-2-yl)-1,4-dimethylbenzene

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); johnphos In N,N-dimethyl-formamide at 80℃; for 0.5h; Inert atmosphere;	98%

: 2487-90-3
trimethoxysilane

: trimethoxysilane lithium

Conditions

Conditions	Yield
With methyllithium In tetrahydrofuran at -78℃; for 6h;	98%

: 2487-90-3
trimethoxysilane

: 917-54-4
methyllithium

: trimethoxysilane lithium

Conditions

Conditions	Yield
In tetrahydrofuran at -78℃; for 6h;	98%

: 2487-90-3
trimethoxysilane

: 172949-96-1
7-acetoxy-6,6-bis(acetoxymethyl)-4-oxa-1-heptene

: C17H32O10Si

Conditions

Conditions	Yield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In toluene at 75 - 85℃; for 1.5h;	98%

: 2487-90-3
trimethoxysilane

: 63905-21-5
3-allyloxy-1,2-propanediol diacetoxide

: C13H26O8Si

Conditions

Conditions	Yield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In toluene at 75 - 85℃; for 1.5h;	98%

: 2487-90-3
trimethoxysilane

: 21652-58-4
1H,1H,2H-perfluorodecene

: 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecyltrimethoxysilane

Conditions

Conditions	Yield
With chloroplatinic acid In isopropyl alcohol at 25℃; for 0.125h; Temperature;	98%

Trimethoxysilane Consensus Reports

Reported in EPA TSCA Inventory.

Trimethoxysilane Standards and Recommendations

DOT Classification: 6.1; Label: Poison, Flammable Liquid

Trimethoxysilane Specification

The Trimethoxy silane, with the CAS registry number 2487-90-3, is also known as Silane, trimethoxy-. It belongs to the product categories of Alkoxy Silanes; Organometallic Reagents; Organosilicon; Trialkoxysilanes; OthersSilsesquioxanes: Poss Nanohybrids; Poss Precursors and Intermediates; RSi(OR)3Organometallic Reagents. Its EINECS registry number is 219-637-2. Its IUPAC name is called trimethoxysilane. This chemical's classification code is Skin / Eye Irritant. It is colorless clear liquid. In addition, it should be stored in a closed containers in a cool, dry place. This chemical can be used as intermediates for the synthesis of silicon and a variety of silane coupling agent.

Physical properties of Trimethoxy silane: (1)ACD/LogP: 3.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.11; (4)ACD/LogD (pH 7.4): 3.11; (5)ACD/BCF (pH 5.5): 134.98; (6)ACD/BCF (pH 7.4): 134.98; (7)ACD/KOC (pH 5.5): 1165.34; (8)ACD/KOC (pH 7.4): 1165.34; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Density: 0.96 g/mL at 25 °C(lit.); (13)Flash Point: 24 °F; (14)Melting Point: -115 °C(lit.); (15)Enthalpy of Vaporization: 30.83 kJ/mol; (16)Boiling Point: 81 °C at 760 mmHg; (17)Vapour Pressure: 92.6 mmHg at 25°C.

Preparation: this chemical can be prepared by silica fume and methanol. This reaction will need the catalyst copper.

Uses of Trimethoxy silane: it can be used to produce (E)-1,4-dimethoxy-2-trimethoxysilyl-2-buten at ambient temperature. This reaction will need Rh(I)-catalyst and solvent tetrahydrofuran with reaction time of 2 hours. The yield is about 98%.

When you are using this chemical, please be cautious about it as the following:
This chemical may catch fire in contact with air which only need brief contact with an ignition source and has a very low flash point or evolve highly flammable gases in contact with water. This chemical that at very low levels may cause damage to health. Highly flammable. It is very toxic by inhalation. It is irritating to eyes. Keep away from sources of ignition - No smoking. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CO[Si](OC)OC
(2)InChI: InChI=1S/C3H9O3Si/c1-4-7(5-2)6-3/h1-3H3
(3)InChIKey: PZJJKWKADRNWSW-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
rabbit	LD50	skin	6300uL/kg (6.3mL/kg)	American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat	LC50	inhalation	42ppm/4H (42ppm)	Toxicologist. Vol. 13, Pg. 152, 1993.
rat	LD50	oral	1560uL/kg (1.56mL/kg)	Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 15, Pg. 261, 1996.

Product Name

Trimethoxysilane

Synthetic route

Trimethoxysilane Consensus Reports

Trimethoxysilane Standards and Recommendations

Trimethoxysilane Specification

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