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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Phosphinylidynetris-(methanol)

Cas:1067-12-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details Item Specification Test Results Appearance White crystalline powder Conform

China Biggest factory Supply High Quality Tri(hydroxymethyl)phosphine oxide CAS 1067-12-5

Cas:1067-12-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1067-12-5 with competitive price

Cas:1067-12-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methanol,1,1',1''-phosphinylidynetris- 1067-12-5

Cas:1067-12-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

phosphinylidynetrimethanol CAS:1067-12-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

phosphinylidynetrimethanol CAS:1067-12-5

Cas:1067-12-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High Quality phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Product Name: phosphinylidynetrimethanol Synonyms: phosphinylidynetrimethanol;Tris(hydroxymethyl)phosphine oxide;Phosphinylidynetrismethanol CAS: 1067-12-5 MF: C3H9O3P MW: 124.075521 Appearance:powder Sto

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Metric Ton

FOB Price: $20.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Sealed in a cool ,dry and microtherm place , avoid light . Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:It is an impo

bis(hydroxymethyl)phosphorylmethanol supplier in China

Cas:1067-12-5

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Methanol,1,1',1''-phosphinylidynetris-

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol Application:TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Other

inquiry

DB BIOTECH CO., LTD

best seller Application:API

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Methanol,1,1',1''-phosphinylidynetris- cas 1067-12-5Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Methanol,1,1',1''-phosphinylidynetris- cas 1067-12-5

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanolAppearance:powder Storage:room tempurature Package:As required Application:medical Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by s

TIANFUCHEM--1067-12-5---phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

phosphinylidynetrimethanol

Cas:1067-12-5

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

tetrakis(hydroxymethyl)phosphonium chloride
124-64-1

tetrakis(hydroxymethyl)phosphonium chloride

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With sodium hydroxide In methanol; water at 50℃; for 2h; Elimination;100%
With barium carbonate In water
With sodium hydroxide
With sodium hydroxide; dihydrogen peroxide at 70 - 80℃; for 1h;
With sodium hydroxide at 20℃; Rate constant;
tris(hydroxymethyl)phosphine
2767-80-8

tris(hydroxymethyl)phosphine

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With air at 80℃; for 5h; Reagent/catalyst; Temperature;95%
With dihydrogen peroxide
With oxygen at 50 - 60℃; for 5h; Green chemistry;220 g
With dihydrogen peroxide In water at 20℃;
With air In water; toluene at 90℃; for 16h;
formaldehyd
50-00-0

formaldehyd

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
Stage #1: formaldehyd With phosphan In 5,5-dimethyl-1,3-cyclohexadiene at 68℃; under 30003 Torr; for 3h; Inert atmosphere; Autoclave; Large scale;
Stage #2: With dihydrogen peroxide In 5,5-dimethyl-1,3-cyclohexadiene at 55℃; for 5h; Solvent; Pressure; Temperature; Inert atmosphere; Large scale;
95%
tetrakis(hydroxymethyl)phosphonium sulfate
77350-08-4

tetrakis(hydroxymethyl)phosphonium sulfate

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
Stage #1: tetrakis(hydroxymethyl)phosphonium sulfate With barium(II) hydroxide In water at 60℃;
Stage #2: With dihydrogen peroxide In water at 20℃;
94%
diiodotris<(trimethylsiloxy)methyl>phosphorane
74858-13-2

diiodotris<(trimethylsiloxy)methyl>phosphorane

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With methanol93%
1-iodo-butane
542-69-8

1-iodo-butane

tris(hydroxymethyl)phosphine
2767-80-8

tris(hydroxymethyl)phosphine

A

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

B

butyl bis(hydroxymethyl)phosphineoxide
17919-46-9

butyl bis(hydroxymethyl)phosphineoxide

Conditions
ConditionsYield
Stage #1: 1-iodo-butane; tris(hydroxymethyl)phosphine In methanol at 0 - 70℃; for 4.5h; Inert atmosphere; Schlenk technique;
Stage #2: With triethylamine at 60℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #3: With dihydrogen peroxide In methanol for 2h;
A 12%
B 45%
tetrakis(hydroxymethyl)phosphonium chloride
124-64-1

tetrakis(hydroxymethyl)phosphonium chloride

A

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

B

tris(hydroxymethyl)phosphine
2767-80-8

tris(hydroxymethyl)phosphine

Conditions
ConditionsYield
Stage #1: tetrakis(hydroxymethyl)phosphonium chloride With sodium hydroxide In ethanol at 20℃; for 1.25h;
Stage #2: With 4 A molecular sieve; potassium carbonate for 6h;
A 20%
B n/a
tetrakis(hydroxymethyl)phosphonium sulphate

tetrakis(hydroxymethyl)phosphonium sulphate

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
Stage #1: tetrakis(hydroxymethyl)phosphonium sulphate With sodium hydroxide
Stage #2:
0.1%
chlorure de tetrakis(hydroxymethyl)phosphonium
16980-25-9

chlorure de tetrakis(hydroxymethyl)phosphonium

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With sodium hydroxide
tris(acetoxymethyl)phosphine oxide
4851-97-2

tris(acetoxymethyl)phosphine oxide

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With hydrogenchloride In methanol
chlorure de tetrakis(hydroxymethyl)phosphonium
16980-25-9

chlorure de tetrakis(hydroxymethyl)phosphonium

A

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

B

tris(hydroxymethyl)phosphine
2767-80-8

tris(hydroxymethyl)phosphine

Conditions
ConditionsYield
With sodium hydroxide
tris<(trimethylsiloxy)methyl>phosphine
63245-87-4

tris<(trimethylsiloxy)methyl>phosphine

A

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

B

tris(chloromethyl)phosphine oxide
4851-89-2

tris(chloromethyl)phosphine oxide

C

bis(chloromethyl)(hydroxymethyl)phosphine oxide
35449-79-7

bis(chloromethyl)(hydroxymethyl)phosphine oxide

D

(chloromethyl)bis(hydroxymethyl)phosphine oxide

(chloromethyl)bis(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With methanol; chlorine 1) CH2Cl2, 20 deg C, 1 h, 2) 20 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
tris<(trimethylsiloxy)methyl>phosphine oxide
63245-88-5

tris<(trimethylsiloxy)methyl>phosphine oxide

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With hydrogenchloride; methanol 1) C6H6; Yield given. Multistep reaction;
dichlorotris<(trimethylsiloxy)methyl>phosphorane
74858-10-9

dichlorotris<(trimethylsiloxy)methyl>phosphorane

A

methylene chloride
74-87-3

methylene chloride

B

Methoxytrimethylsilane
1825-61-2

Methoxytrimethylsilane

C

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With methanol In dichloromethane at -70℃; Yield given;
dibromotris<(trimethylsiloxy)methyl>phosphorane
74872-34-7

dibromotris<(trimethylsiloxy)methyl>phosphorane

A

Methoxytrimethylsilane
1825-61-2

Methoxytrimethylsilane

B

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With methanol In dichloromethane at -70℃; Yield given;
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

1,4-dioxo-2,6,7-trioxa-1,4-diphosphabicyclo[2.2.2]octane
4726-80-1

1,4-dioxo-2,6,7-trioxa-1,4-diphosphabicyclo[2.2.2]octane

Conditions
ConditionsYield
With sodium methylate; phosphorous acid trimethyl ester at 150℃; for 5h; Temperature; Reagent/catalyst; Inert atmosphere;96.2%
With trimethyl phosphite; sodium methylate at 150℃; for 6h; Reagent/catalyst; Temperature; Inert atmosphere;95.5%
With trichlorophosphate In 1,4-dioxane; water at 10 - 100℃; for 6h; Solvent; Temperature;95.3%
With phosphoric acid triphenyl ester; sodium methylate at 150℃; for 8h; Reagent/catalyst; Temperature; Inert atmosphere;93.2%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris-O, O-2-hydroxymethylphosphonophosphoryl phosphonitrile

tris-O, O-2-hydroxymethylphosphonophosphoryl phosphonitrile

Conditions
ConditionsYield
With pyridine; 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine at 130℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;96.1%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

C4H10O5P2

C4H10O5P2

Conditions
ConditionsYield
With sodium methylate; methoxybenzene at 150℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;95.9%
P,P-dichlorophenylphosphine oxide
824-72-6

P,P-dichlorophenylphosphine oxide

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

C9H12O5P2

C9H12O5P2

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 20 - 140℃; for 6h; Solvent; Temperature;95.3%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

1,1-dimethyl-1-sila-2,6-dioxa-4-oxy-4-phospha-4-hydroxymethylcyclohexane

1,1-dimethyl-1-sila-2,6-dioxa-4-oxy-4-phospha-4-hydroxymethylcyclohexane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 40 - 130℃; for 13h; Solvent; Temperature;95.3%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

4-oxo-2,6,7-trioxa-1,4-diphosphabicyclo[2.2.2]octane

4-oxo-2,6,7-trioxa-1,4-diphosphabicyclo[2.2.2]octane

Conditions
ConditionsYield
With phosphorus trichloride In acetonitrile at 0 - 80℃; for 4h; Reagent/catalyst; Temperature;94.4%
With triphenyl phosphite; sodium methylate at 150℃; for 7h; Temperature; Reagent/catalyst; Inert atmosphere;94.7%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

phenylthiophosphonic acid dichloride
3497-00-5

phenylthiophosphonic acid dichloride

C9H12O4P2S

C9H12O4P2S

Conditions
ConditionsYield
at 20 - 160℃; for 7h; Temperature; Inert atmosphere;94.2%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris(chloromethyl)phosphine oxide
4851-89-2

tris(chloromethyl)phosphine oxide

Conditions
ConditionsYield
With phosphorus pentachloride In chloroform at 60℃; Chlorination;86%
With pyridine; thionyl chloride
With hydrogenchloride at 180 - 200℃; for 8h; Yield given;
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

tris(allyloxymethyl)phosphine oxide

tris(allyloxymethyl)phosphine oxide

Conditions
ConditionsYield
Stage #1: tri(hydroxymethyl)phosphine oxide With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In water at 35℃; Green chemistry;
Stage #2: 3-chloroprop-1-ene In water at 0 - 50℃; for 12h; Green chemistry;
80%
With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In water at 0 - 45℃; for 12h;75%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

propargyl bromide
106-96-7

propargyl bromide

tris(prop-2-yn-1-yloxymethyl)phosphane oxide

tris(prop-2-yn-1-yloxymethyl)phosphane oxide

Conditions
ConditionsYield
Stage #1: tri(hydroxymethyl)phosphine oxide With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In water at 35℃; Williamson Ether Synthesis;
Stage #2: propargyl bromide In water; toluene at 0 - 50℃; for 12h; Williamson Ether Synthesis;
62.9%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

C24H27O6P

C24H27O6P

Conditions
ConditionsYield
With pyridine at 20℃; for 20h;51%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

(bis-(DMT-oxymethyl))(hydroxymethyl)phosphine oxide

(bis-(DMT-oxymethyl))(hydroxymethyl)phosphine oxide

Conditions
ConditionsYield
With pyridine at 20℃; for 20h;50%
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

sirolimus
53123-88-9

sirolimus

(21E,23E,25E,26E,31R,32S,33R,34R,36S,38S,41S,42R,43R,52R)-40-[bis(hydroxymethyl)phosphorylmethoxy]-42,52-dihydroxy-41-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl]-1-methyl-ethyl]-43-methoxy-31,32,33,34,44,45-hexamethyl-65,66-dioxa-53-azatricyclohexatriaconta-21,23,25(44),26(45)-tetraene-46,47,48,49,50-pentone

(21E,23E,25E,26E,31R,32S,33R,34R,36S,38S,41S,42R,43R,52R)-40-[bis(hydroxymethyl)phosphorylmethoxy]-42,52-dihydroxy-41-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl]-1-methyl-ethyl]-43-methoxy-31,32,33,34,44,45-hexamethyl-65,66-dioxa-53-azatricyclohexatriaconta-21,23,25(44),26(45)-tetraene-46,47,48,49,50-pentone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In tetrahydrofuran; water at 25℃; for 4h;9%
n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris-lauroyloxymethyl-phosphine oxide
4851-93-8

tris-lauroyloxymethyl-phosphine oxide

Conditions
ConditionsYield
With water
tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

bis(hydroxymethyl)phosphinic acid
2074-67-1

bis(hydroxymethyl)phosphinic acid

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

bis(hydroxymethyl)phosphinic acid
2074-67-1

bis(hydroxymethyl)phosphinic acid

Conditions
ConditionsYield
With sodium hydroxide
1-bromo-butane
109-65-9

1-bromo-butane

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris-butoxymethyl-phosphane oxide
53695-03-7

tris-butoxymethyl-phosphane oxide

Conditions
ConditionsYield
(i) NaOMe, benzene, (ii) /BRN= 1098260/; Multistep reaction;
methyl bromide
74-83-9

methyl bromide

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris-methoxymethyl-phosphane oxide
41528-71-6

tris-methoxymethyl-phosphane oxide

Conditions
ConditionsYield
(i) NaOMe, benzene, (ii) /BRN= 1209223/, toluene; Multistep reaction;
ethyl bromide
74-96-4

ethyl bromide

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris(ethoxymethyl)phosphine oxide
13830-01-8

tris(ethoxymethyl)phosphine oxide

Conditions
ConditionsYield
(i) NaOMe, benzene, (ii) /BRN= 1209224/, toluene; Multistep reaction;
formaldehyd
50-00-0

formaldehyd

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

(5-oxo-5λ5-[1,3,5]dioxaphosphinan-5-yl)-methanol
69805-21-6

(5-oxo-5λ5-[1,3,5]dioxaphosphinan-5-yl)-methanol

Conditions
ConditionsYield
at 180 - 200℃;
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris<(trimethylsiloxy)methyl>phosphine oxide
63245-88-5

tris<(trimethylsiloxy)methyl>phosphine oxide

1-Bromopentane
110-53-2

1-Bromopentane

tri(hydroxymethyl)phosphine oxide
1067-12-5

tri(hydroxymethyl)phosphine oxide

tris-pentyloxymethyl-phosphane oxide
18982-80-4

tris-pentyloxymethyl-phosphane oxide

Conditions
ConditionsYield
(i) NaOMe, benzene, (ii) /BRN= 1730981/; Multistep reaction;

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