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Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:w

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methanephosphonic acid dimethyl ester

Cas:756-79-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

Dimethyl methylphosphonate CAS 756-79-6

Cas:756-79-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phosphonic acid,P-methyl-, dimethyl ester 756-79-6

Cas:756-79-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Dimethyl methylphosphonate CAS:756-79-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Dimethyl methylphosphonate CAS:756-79-6

Cas:756-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phosphonic acid,P-methyl-, dimethyl ester

Cas:756-79-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:756-79-6

Cas:756-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colourless liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Widely used fo

Phosphonic acid,P-methyl-, dimethyl ester

Cas:756-79-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Kilogram

FOB Price: $400.0 / 450.0

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Chemical Name: Dimethyl Methyl Phosphonate Synonyms: Flame Retardant DMMP CAS NO.: 756-79-6 Molecular formula: C3H9O3P Technical Index: Appearance: colorless transparent liquid Water content(%) 0.1max Density(25oC):1.16 ± 0.00

Dimethyl Methyl Phosphonate-DMMP CAS 756-79-6

Cas:756-79-6

Min.Order:3 Metric Ton

FOB Price: $1.0

Type:Other

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Flame retardant DMMP

Cas:756-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top QualityDimethyl methylphosphonate

Cas:756-79-6

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Dimethyl methylphosphonate Basic information Product Name: Dimethyl methylphosphonate Synonyms: Dimethoxymethylphosphine oxide;dimethoxymethylphosphineoxide;Dimethyl ester of methylphosphonic acid;dimethylmethanephosphate;Furan tf 2000;Fyrol d

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--High purity Dimethyl methylphosphonate factory price

Cas:756-79-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Luyunjia Chemistry Xiamen Limited

HK Luyunjia Chemical Industry Co.,Ltd is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic drug. and

Dimethyl methanephosphonate

Cas:756-79-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

My Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:0

Negotiable

Type:Manufacturers

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Dimethyl methylphosphonate

Cas:756-79-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--High purity Dimethyl methylphosphonate factory price

Cas:756-79-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Phosphonic acid,P-methyl-, dimethyl ester

Cas:756-79-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Dimethyl phosphonate cas no. 756-79-6 98%

Cas:756-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Phosphonic acid,P-methyl-, dimethyl ester

Cas:756-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

DiMethyl Methylphosphonate

Cas:756-79-6

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Dimethyl methanephosphonate

Cas:756-79-6

Min.Order:0

Negotiable

Type:Manufacturers

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Synthetic route

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

methyl iodide
74-88-4

methyl iodide

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
In neat (no solvent) at 100℃; for 0.138833h; Solvent; Arbuzov Reaction; Flow reactor;99%
for 1h; Irradiation;95%
for 0.0833333h; Michaelis-Arbuzov reaction; microwave irradiation;95%
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With iodine for 24h; Heating;99%
With trimethylsilyl trifluoromethanesulfonate In chloroform at 60℃; for 18h; Michaelis-Arbuzov rearrangement;98%
With trimethylsilyl iodide at 50℃; for 6h; Michaelis-Arbuzov rearrangement;95%
1,1,1-tri(hydroxymethyl)propane
77-99-6

1,1,1-tri(hydroxymethyl)propane

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
Stage #1: 1,1,1-tri(hydroxymethyl)propane; phosphorous acid trimethyl ester at 80 - 120℃; for 4h;
Stage #2: With methyl p-toluene sulfonate at 170 - 180℃; for 2h; Reagent/catalyst; Temperature;
96%
methylphosphonic acid dichloroanhydride
676-97-1

methylphosphonic acid dichloroanhydride

methanol
67-56-1

methanol

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With aluminum oxide at 20℃;95%
With triethylamine80%
benzyl bromide
100-39-0

benzyl bromide

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

dimethyl benzylphosphonate
773-47-7

dimethyl benzylphosphonate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 120℃; for 9h;A 95%
B 144 g
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

1-Bromo-2-bromomethyl-benzene
3433-80-5

1-Bromo-2-bromomethyl-benzene

A

dimethyl (2-bromobenzyl)phosphonate
103474-07-3

dimethyl (2-bromobenzyl)phosphonate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
A 93%
B n/a
ethyl 4-(acetoxymethyl)-2-(bromomethyl)-5-tert-butylfuran-3-carboxylate

ethyl 4-(acetoxymethyl)-2-(bromomethyl)-5-tert-butylfuran-3-carboxylate

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

B

ethyl 4-(acetoxymethyl)-5-tert-butyl-2-(dimethoxyphosphorylmethyl)furan-3-carboxylate

ethyl 4-(acetoxymethyl)-5-tert-butyl-2-(dimethoxyphosphorylmethyl)furan-3-carboxylate

Conditions
ConditionsYield
at 100 - 140℃; for 0.2h; Arbuzov reaction;A n/a
B 90%
methanol
67-56-1

methanol

methylphosphonic acid
993-13-5

methylphosphonic acid

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With tetrachlorosilane at 0℃;89%
With p-TsOH-Celite at 20℃;87%
Stage #1: methylphosphonic acid With 1H-imidazole; iodine In dichloromethane at 45 - 50℃; for 0.5h; Gareg-Samuelsson reaction;
Stage #2: methanol In dichloromethane at 45 - 50℃; for 0.666667h; Gareg-Samuelsson reaction;
85%
1,2,2,2-tetrachloro-1-isocyanato-ethane
15145-29-6

1,2,2,2-tetrachloro-1-isocyanato-ethane

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

2,2-dichloro-1-(dimethoxyphosphinyl)vinyl isocyanate
85978-66-1

2,2-dichloro-1-(dimethoxyphosphinyl)vinyl isocyanate

B

2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl isocyanate
85978-65-0

2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl isocyanate

C

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 100℃; for 1h;A 7%
B n/a
C 81%
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

Benzyl bromoacetate
5437-45-6

Benzyl bromoacetate

A

benzyl 2-(dimethoxyphosphoryl)acetate
57443-18-2

benzyl 2-(dimethoxyphosphoryl)acetate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 85℃; for 60h;A 81%
B n/a
iodobenzene
591-50-4

iodobenzene

Dimethyl phosphite
868-85-9

Dimethyl phosphite

A

dimethyl phenylphosphonate
2240-41-7

dimethyl phenylphosphonate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; palladium diacetate; triphenylphosphine In acetonitrile at 70℃; for 4h; Title compound not separated from byproducts;A 80%
B n/a
Dimethyl phosphite
868-85-9

Dimethyl phosphite

methyl iodide
74-88-4

methyl iodide

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
Stage #1: Dimethyl phosphite With sodium hydroxide for 0.25h; Michaelis-Becker reaction; Ionic liquid;
Stage #2: methyl iodide for 12h; Michaelis-Becker reaction; Ionic liquid;
80%
Stage #1: Dimethyl phosphite With sodium In dichloromethane for 40h; Heating;
Stage #2: methyl iodide In dichloromethane for 10h; Michaelis-Becker reaction; Heating;
trimethyl phosphonoformate
31142-23-1

trimethyl phosphonoformate

A

trimethyl phosphite
512-56-1

trimethyl phosphite

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 295℃; for 6h;A 18%
B 75%
dichloromethane
75-09-2

dichloromethane

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With tetraethylammonium bromide; cyclohexene at 20℃; electrolysis, Pt electrodes;75%
methanol
67-56-1

methanol

methyl hydrogen methylphosphonate
1066-53-1

methyl hydrogen methylphosphonate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With polymer supported sulfonated magnetic resin In toluene at 20 - 70℃; for 0.75h;74%
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

trimethyl phosphite
512-56-1

trimethyl phosphite

B

O,O,O-trimethylthiophosphate
152-18-1

O,O,O-trimethylthiophosphate

C

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With sulfur trioxide In dichloromethane at -95℃;A 25%
B 4%
C 71%
carbonic acid bromomethyl ester 1-ethoxy-ethyl ester

carbonic acid bromomethyl ester 1-ethoxy-ethyl ester

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

1-ethoxyethyl O,O-dimethylphosphorylethanoate
749887-15-8

1-ethoxyethyl O,O-dimethylphosphorylethanoate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 50 - 60℃; for 2.5h; Arbuzov reaction;A 71%
B 25.9%
methanol
67-56-1

methanol

A

trimethyl phosphite
512-56-1

trimethyl phosphite

B

Dimethyl phosphite
868-85-9

Dimethyl phosphite

C

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With phosphorous; tetraethylammonium iodide In acetonitrile at 18℃; electrolysis;A 70%
B 11%
C 3%
With phosphorous; tetraethylammonium iodide In acetonitrile at 18℃; Mechanism; Product distribution; electrolysis; var. nucleophiles; var. temperatures;A 70%
B 11%
C 3%
With phosphorous In acetonitrile at 18℃; Electrolysis;A 70%
B 11%
C 3%
methyl phosphite
96-36-6, 868-85-9

methyl phosphite

methyl iodide
74-88-4

methyl iodide

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With potassium carbonate at 25℃; for 4h;70%
With potassium carbonate at 25℃; for 4h; other phosphonates;70%
carbonic acid 1-ethoxy-ethyl ester iodomethyl ester

carbonic acid 1-ethoxy-ethyl ester iodomethyl ester

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

1-ethoxyethyl O,O-dimethylphosphorylethanoate
749887-15-8

1-ethoxyethyl O,O-dimethylphosphorylethanoate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
at 40 - 50℃; for 2h; Arbuzov reaction;A 67.2%
B 27.4%
dimethyl (1-methylethyl) phosphite
52956-34-0

dimethyl (1-methylethyl) phosphite

methyl iodide
74-88-4

methyl iodide

A

isopropyl methyl methylphosphonate
690-64-2

isopropyl methyl methylphosphonate

B

diisopropyl methyl phosphonate

diisopropyl methyl phosphonate

C

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
for 2h; Arbusov rearrangement; Heating;A 66%
B 7 % Chromat.
C 3 % Chromat.
Dimethyl phosphite
868-85-9

Dimethyl phosphite

MeX (X = Br or I)

MeX (X = Br or I)

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With tetraethylammonium bromide In acetonitrile at 20℃; on a platinum electrode;65%
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

trimethyl phosphite
512-56-1

trimethyl phosphite

B

O,O,O-trimethylthiophosphate
152-18-1

O,O,O-trimethylthiophosphate

C

dimethyl sulfate
77-78-1

dimethyl sulfate

D

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With sulfur trioxide In dichloromethane at -78℃; Product distribution; other trialkyl phosphite,trialkyl phosphine, trialkyl arsines, trialkoxyarsines, var. molar ratio and temperatures;A 22%
B 4%
C 55%
D 19%
With sulfur trioxide In dichloromethane at -78℃;A 48%
B 16%
C 3%
D 9%
methanol
67-56-1

methanol

A

trimethyl phosphite
512-56-1

trimethyl phosphite

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With phosphorous; tetraethylammonium iodide In acetonitrile at 50℃; electrolysis;A 51%
B 28%
With phosphorous In acetonitrile at 50℃; Electrolysis;A 51%
B 28%
benzophenone
119-61-9

benzophenone

dimethyl α-trimethylsilylmethylphosphonate
13433-42-6

dimethyl α-trimethylsilylmethylphosphonate

A

1,1-Diphenylethylene
530-48-3

1,1-Diphenylethylene

B

dimethyl (2,2-diphenylvinyl)phosphonate
71265-07-1

dimethyl (2,2-diphenylvinyl)phosphonate

C

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With cesium fluorideA 20%
B 30%
C 50%
With cesium fluoride In tetrahydrofuran for 24h; Heating;A 20%
B 30%
C 50%
propargyl bromide
106-96-7

propargyl bromide

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

Dimethyl propargylphosphonate
4885-44-3

Dimethyl propargylphosphonate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
for 5h; Heating;A 45%
B n/a
phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

Dimethyl propargylphosphonate
4885-44-3

Dimethyl propargylphosphonate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
With propargyl bromide for 5h; Heating;A 45%
B n/a
methyl trifluoromethanesulfonate
333-27-7

methyl trifluoromethanesulfonate

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

methyltrimethoxyphosphonium triflate
64294-66-2

methyltrimethoxyphosphonium triflate

B

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

Conditions
ConditionsYield
In chloroform-d1 at 0 - 20℃; for 1h; Time; Inert atmosphere; Schlenk technique;A 45%
B 27 %Spectr.
benzaldehyde
100-52-7

benzaldehyde

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl (2-hydroxy-2-phenyl)ethylphosphonate

dimethyl (2-hydroxy-2-phenyl)ethylphosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.0833333h; Metallation;
Stage #2: benzaldehyde In tetrahydrofuran; hexane at -78℃; for 0.0833333h; Addition;
100%
With n-butyllithium 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 -> -20 deg C; Yield given. Multistep reaction;
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran at -70℃; Inert atmosphere;
Stage #2: benzaldehyde In tetrahydrofuran Inert atmosphere;
(S)-3-(4-Methoxy-benzyl)-2,2-dimethyl-oxazolidine-4-carboxylic acid methyl ester
231291-83-1

(S)-3-(4-Methoxy-benzyl)-2,2-dimethyl-oxazolidine-4-carboxylic acid methyl ester

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

{2-[(S)-3-(4-Methoxy-benzyl)-2,2-dimethyl-oxazolidin-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester
231291-85-3

{2-[(S)-3-(4-Methoxy-benzyl)-2,2-dimethyl-oxazolidin-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78℃;100%
N-carbobenzoxy-L-phenylalanine methyl ester
35909-92-3

N-carbobenzoxy-L-phenylalanine methyl ester

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl [(3S)-4-phenyl-3-[(benzyloxycarbonyl)amino]-2-oxobutyl]phosphonate
347851-53-0

dimethyl [(3S)-4-phenyl-3-[(benzyloxycarbonyl)amino]-2-oxobutyl]phosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: N-carbobenzoxy-L-phenylalanine methyl ester In tetrahydrofuran; hexane Further stages.;
100%
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexanes at -78℃; under 760.051 Torr; for 0.333333h;
Stage #2: N-carbobenzoxy-L-phenylalanine methyl ester In tetrahydrofuran; hexanes at -78 - 20℃; under 760.051 Torr; for 1.25h;
Stage #3: With water; acetic acid In tetrahydrofuran; hexanes at 0℃; under 760.051 Torr;
100%
2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate
150765-78-9

2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

1-(dimethylphosphonato)-2-oxo-6-octyne
475467-02-8

1-(dimethylphosphonato)-2-oxo-6-octyne

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h;
Stage #2: 2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate In tetrahydrofuran; hexane at -78 - 60℃; for 1.33333h; Inert atmosphere;
100%
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: 2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate In tetrahydrofuran; hexane at -78 - 60℃; Inert atmosphere;
Stage #3: With water; ammonium chloride In tetrahydrofuran; diethyl ether; hexane Inert atmosphere;
97%
Stage #1: dimethyl methane phosphonate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: 2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate In tetrahydrofuran at -78 - 60℃; for 1.33333h; Claisen condensation;
21%
Stage #1: dimethyl methane phosphonate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: 2-methyl-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate In tetrahydrofuran at -78 - 60℃; Claisen condensation;
21%
Benzyloxymethyl-oxiran
2930-05-4

Benzyloxymethyl-oxiran

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl 4-(benzyloxy)-3-hydroxybutanephosphonate
476310-16-4

dimethyl 4-(benzyloxy)-3-hydroxybutanephosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #2: Benzyloxymethyl-oxiran With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -70℃; for 2h;
100%
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran at -78℃; for 0.25h;
Stage #2: Benzyloxymethyl-oxiran With boron trifluoride diethyl etherate In tetrahydrofuran at -70℃; for 2h;
100%
methyl 3-(adamantan-1-yl)propanoate
29542-59-4

methyl 3-(adamantan-1-yl)propanoate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl 2-oxo-4-(1-adamantyl)butylphosphonate
53273-30-6

dimethyl 2-oxo-4-(1-adamantyl)butylphosphonate

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane; water100%
methyl 2-((tert-butyl(diphenyl)silyl)oxy)acetate
154698-92-7

methyl 2-((tert-butyl(diphenyl)silyl)oxy)acetate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl 3-(tert-butyldiphenylsilyl)oxy-2-oxopropylphosphonate
1075244-38-0

dimethyl 3-(tert-butyldiphenylsilyl)oxy-2-oxopropylphosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: methyl 2-((tert-butyl(diphenyl)silyl)oxy)acetate In tetrahydrofuran; hexane for 0.5h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water
100%
1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate
73323-65-6

1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

(R)-1-tert-butyl 2-(2-(dimethoxyphosphoryl)acetyl)pyrrolidine-1-carboxylate
1140496-59-8

(R)-1-tert-butyl 2-(2-(dimethoxyphosphoryl)acetyl)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexanes at -78℃; for 0.5h;
Stage #2: 1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate In tetrahydrofuran; hexanes at -78℃; for 3h;
Stage #3: With water; ammonium chloride In tetrahydrofuran; hexanes
100%
dimethyl (2S)-N-(triphenylmethyl)aspartate
116393-72-7

dimethyl (2S)-N-(triphenylmethyl)aspartate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

methyl (2S)-2-(tritylamino)-4-oxo-5-(dimethoxyphosphoryl)pentanoate
1197335-24-2

methyl (2S)-2-(tritylamino)-4-oxo-5-(dimethoxyphosphoryl)pentanoate

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78℃; Inert atmosphere; regioselective reaction;100%
With n-butyllithium In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;92%
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: dimethyl (2S)-N-(triphenylmethyl)aspartate In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;
92%
ethyl 4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate
1309567-74-5

ethyl 4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl (2-(4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-oxoethyl)phosphonate
1309567-75-6

dimethyl (2-(4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-oxoethyl)phosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78 - -20℃; for 0.25h; Inert atmosphere;
Stage #2: ethyl 4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate In tetrahydrofuran; hexane at -78 - 0℃; for 0.166667h; Inert atmosphere;
100%
C17H28O4

C17H28O4

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

C19H33O6P

C19H33O6P

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: C17H28O4 In tetrahydrofuran; hexane at -78℃; for 2h;
Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water at -78℃;
100%
methyl 5-methylpyridine-2-carboxylate
29681-38-7

methyl 5-methylpyridine-2-carboxylate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

C10H14NO4P
1369491-73-5

C10H14NO4P

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: methyl 5-methylpyridine-2-carboxylate In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water
100%
methyl 2,3-O-isopropylidene-α-D-mannopyranoside-4,6-cyclic sulfate
139978-82-8

methyl 2,3-O-isopropylidene-α-D-mannopyranoside-4,6-cyclic sulfate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

[2-((2R,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-methoxy-tetrahydro-pyran-2-yl)-ethyl]-phosphonic acid dimethyl ester
454183-61-0

[2-((2R,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-methoxy-tetrahydro-pyran-2-yl)-ethyl]-phosphonic acid dimethyl ester

Conditions
ConditionsYield
Stage #1: methyl-2,3-O-isopropylidene-4,6-cyclic sulfate-α-D-mannopyranoside; dimethyl methane phosphonate With 1,1-Diphenylethylene; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In tetrahydrofuran at -78℃;
Stage #2: In tetrahydrofuran; methanol regioselective reaction;
100%
dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

ethyl 4-iodopent-4-enoate

ethyl 4-iodopent-4-enoate

dimethyl (5-iodo-2-oxohex-5-en-1-yl)phosphonate
1569075-94-0

dimethyl (5-iodo-2-oxohex-5-en-1-yl)phosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: ethyl 4-iodopent-4-enoate In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
100%
methyl 2-(((tert-butoxycarbonyl)oxy)methyl)benzofuran-5-carboxylate

methyl 2-(((tert-butoxycarbonyl)oxy)methyl)benzofuran-5-carboxylate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

tert-butyl ((5-(2-(dimethoxyphosphoryl)acetyl)-1-benzofuran-2-yl)methyl) carbonate

tert-butyl ((5-(2-(dimethoxyphosphoryl)acetyl)-1-benzofuran-2-yl)methyl) carbonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: methyl 2-(((tert-butoxycarbonyl)oxy)methyl)benzofuran-5-carboxylate In tetrahydrofuran; hexane at -78℃; for 2h;
100%
dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

A

methylphosphonic acid dichloroanhydride
676-97-1

methylphosphonic acid dichloroanhydride

B

methylene chloride
74-87-3

methylene chloride

Conditions
ConditionsYield
With thionyl chloride; N-Formylpiperidine for 19h; Heating; various conditions and cactalasts investigated;A 99.2%
B n/a
3-[2-(tert-Butyl-dimethyl-silanyloxy)-4-(trityl-amino)-phenyl]-propionic acid methyl ester
117625-50-0

3-[2-(tert-Butyl-dimethyl-silanyloxy)-4-(trityl-amino)-phenyl]-propionic acid methyl ester

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

{4-[2-(tert-Butyl-dimethyl-silanyloxy)-4-(trityl-amino)-phenyl]-2-oxo-butyl}-phosphonic acid dimethyl ester
110828-45-0

{4-[2-(tert-Butyl-dimethyl-silanyloxy)-4-(trityl-amino)-phenyl]-2-oxo-butyl}-phosphonic acid dimethyl ester

Conditions
ConditionsYield
With n-butyllithium99%
With n-butyllithium Yield given;
methyl (4Z)-6,6,9-trimethyl-10-(tetrahydropyranyloxy)dec-6-en-2-ynoate
260970-23-8

methyl (4Z)-6,6,9-trimethyl-10-(tetrahydropyranyloxy)dec-6-en-2-ynoate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

(7Z)-1-dimethoxyphosphiryl-7,10,10-trimethyl-11-(tetrahydropyranyloxy)undec-7-en-3-yn-2-one
260970-36-3

(7Z)-1-dimethoxyphosphiryl-7,10,10-trimethyl-11-(tetrahydropyranyloxy)undec-7-en-3-yn-2-one

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; Substitution;99%
Dodecanal
112-54-9

Dodecanal

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl 2-hydroxytridecylphosphonate
88708-59-2

dimethyl 2-hydroxytridecylphosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.0833333h; Metallation;
Stage #2: Dodecanal In tetrahydrofuran; hexane at -78℃; for 0.0833333h; Addition;
99%
(S)-methyl 2-palmitamido-3-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)propanoate
935548-14-4

(S)-methyl 2-palmitamido-3-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)propanoate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

(S)-dimethyl 2-oxo-3-palmitamido-4-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)butylphosphonate
935548-32-6

(S)-dimethyl 2-oxo-3-palmitamido-4-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)butylphosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran at -78℃; for 0.25h; Inert atmosphere;
Stage #2: (S)-methyl 2-palmitamido-3-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)propanoate In tetrahydrofuran at -78℃; for 0.333333h; Inert atmosphere;
99%
Stage #1: dimethyl methane phosphonate With n-butyllithium
Stage #2: (S)-methyl 2-palmitamido-3-(4-((4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methoxy)phenyl)propanoate at -78℃; for 3h;
C36H54N2O5Si

C36H54N2O5Si

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

C37H56NO7PSi

C37H56NO7PSi

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78℃;99%
dihydro isoquinoline-1-methyl formate

dihydro isoquinoline-1-methyl formate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl 2-(1-isoquinolinyl)-2-oxoethyl phosphonate

dimethyl 2-(1-isoquinolinyl)-2-oxoethyl phosphonate

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -60 - 20℃; for 2h;99%
butyryl chloride
141-75-3

butyryl chloride

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl (2-oxopentyl)phosphonate
65921-74-6

dimethyl (2-oxopentyl)phosphonate

Conditions
ConditionsYield
99%
ziconium(IV) oxychloride octahydrate
13520-92-8

ziconium(IV) oxychloride octahydrate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

zirconium bis(methylphosphonate)

zirconium bis(methylphosphonate)

Conditions
ConditionsYield
With aq. HCl In water reflux (24 h or 112 h); aq. HBr or H2O alone may also be used; filtration, washing (H2O; acetone), drying (40°C, 18 h, then 200°C, 24 h); elem. anal.;99%
methyl 3-pyridinecarboxylate
93-60-7

methyl 3-pyridinecarboxylate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

lithio dimethyl (2-oxo-2-pyridin-3-ylethyl)phosphonate

lithio dimethyl (2-oxo-2-pyridin-3-ylethyl)phosphonate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran Barbier reaction; Cooling with ice; Inert atmosphere;99%
methyl 4-iodobenzoate
619-44-3

methyl 4-iodobenzoate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

lithio dimethyl [2-(4-iodophenyl)-2-oxoethyl]phosphonate

lithio dimethyl [2-(4-iodophenyl)-2-oxoethyl]phosphonate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran Barbier reaction; Cooling with ice; Inert atmosphere;99%
N-Ethylimidazole
7098-07-9

N-Ethylimidazole

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

[EMIM] methyl methylphosphonate
1059603-87-0

[EMIM] methyl methylphosphonate

Conditions
ConditionsYield
at 100℃; for 24h; Neat (no solvent);99%
methyl-2-[N-(2,4,6-trimethylbenzenesulfonyl)amino]-3-phenyl-propionate
1439462-50-6

methyl-2-[N-(2,4,6-trimethylbenzenesulfonyl)amino]-3-phenyl-propionate

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

dimethyl-{3-[N-(2,4,6-trimethylbenzenesulfonyl)amino]-2-oxo-4-phenyl-butyl}phosphonate
1439462-62-0

dimethyl-{3-[N-(2,4,6-trimethylbenzenesulfonyl)amino]-2-oxo-4-phenyl-butyl}phosphonate

Conditions
ConditionsYield
Stage #1: dimethyl methane phosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: methyl-2-[N-(2,4,6-trimethylbenzenesulfonyl)amino]-3-phenyl-propionate In tetrahydrofuran; hexane at -78 - 0℃; for 5h; Inert atmosphere;
99%
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