Name:GLYX 13 Type: Pharmaceutical Peptide CAS:117928-94-6 Purity:98% Appearance:White powder Packing Specification:1g, 10g, 100g Storage:2 ℃ to 8 ℃ Molecular Formula:C18H31N5O6 Molecular Weight: 413.47
Cas:117928-94-6
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryGood day! I am May Zhang from Hebei Muhuang Technology Co., Ltd. We can provide you with chemical raw materials, chemical products, pharmaceutical intermediates, veterinary intermediates, dye intermediates, pigments, cosmetic raw materials and chem
Cas:117928-94-6
Min.Order:1 Gram
FOB Price: $1.0
Type:Trading Company
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:117928-94-6
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryDayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. Near 20 years DayangChem has provided dif
Cas:117928-94-6
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:117928-94-6
Min.Order:1 Metric Ton
FOB Price: $1.0 / 3.0
Type:Trading Company
inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
Cas:117928-94-6
Min.Order:1 Kilogram
FOB Price: $48.0 / 58.0
Type:Trading Company
inquiryOur company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company
Cas:117928-94-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:117928-94-6
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryAppearance:white or tan powder Storage:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C Package:25kg/Barrel Application:intermediates Transportation:Express/Sea/Air Port:Any port in China
Cas:117928-94-6
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryGLYX 13 CAS:117928-94-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryXi'an Yinherb Bio-Tech Co., Ltd was founded in 2009, We have more than 10 experienced doctors and scientists and professional managers, specializing in Nootropics, Sarms and Peptides researching and developing, and become the lead
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competitive pric
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:117928-94-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:117928-94-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryPacking: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryNote:Due to policy changes, some products have not been disclosed on here. However, you can still ask us for quotations please leave me a message。 If you couldn't find the product you want in our store, maybe we haven't uploaded the co
Cas:117928-94-6
Min.Order:1 box
FOB Price: $20.0 / 50.0
Type:Trading Company
inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
Cas:117928-94-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:117928-94-6
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:117928-94-6
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct name: Rapastinel CAS No.: 117928-94-6 Molecule Formula:C18H31N5O6 Molecule Weight:413.47 Purity: 98.0% Package: 1g/bag Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:117928-94-6
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
GLYX13 英文同义词L-ThreoninaMide,L-threonyl-L-prolyl-L-prolyl-;GLYX-13trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamidetrifluorChemicalbookoacetate;GLYX13;Thr-Pro-Pro-Thr-NH2trifluoroacetate;TPPT-amidetrifluoroacetate;Rapastinel;GIYX-13 CAS号
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With Octanethiol; tert-butylamine In N,N-dimethyl-formamide at 20℃; for 0.5h; | 97% |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; under 2250.23 - 3000.3 Torr; Large scale; | 95% |
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 2327.23 - 3102.97 Torr; Industrial scale; | 43.5% |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 2.2: -5 - 35 °C / Industrial scale 3.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 4 steps 1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 2: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 3: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 4: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 1.2: -5 - 35 °C / Industrial scale 2.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 3 steps 1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 2: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 3: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
L-proline
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: thionyl chloride / 0 - 25 °C / Industrial scale 2.1: dicyclohexyl-carbodiimide; triethylamine / dichloromethane / 0 - 30 °C / Industrial scale 3.1: lithium hydroxide; water / tetrahydrofuran / 18 h / 20 - 30 °C / Industrial scale 4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 0.5 h / -5 - 5 °C / Industrial scale 4.2: 22 h / -5 - 30 °C / Industrial scale 5.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 6.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 6.2: -5 - 35 °C / Industrial scale 7.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 8 steps 1.1: thionyl chloride / 0 - 25 °C / Industrial scale 2.1: sodium hydroxide / water / 0 - 5 °C / Industrial scale 3.1: dicyclohexyl-carbodiimide; triethylamine / dichloromethane / 0 - 30 °C / Industrial scale 4.1: lithium hydroxide; water / tetrahydrofuran / 18 h / 20 - 30 °C / Industrial scale 5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 0.5 h / -5 - 5 °C / Industrial scale 5.2: 22 h / -5 - 30 °C / Industrial scale 6.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 7.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 7.2: -5 - 35 °C / Industrial scale 8.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme |
N-Benzyloxycarbonyl-L-proline
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: dicyclohexyl-carbodiimide; triethylamine / dichloromethane / 0 - 30 °C / Industrial scale 2.1: lithium hydroxide; water / tetrahydrofuran / 18 h / 20 - 30 °C / Industrial scale 3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 0.5 h / -5 - 5 °C / Industrial scale 3.2: 22 h / -5 - 30 °C / Industrial scale 4.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 5.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 5.2: -5 - 35 °C / Industrial scale 6.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 6 steps 1: 4-methyl-morpholine; isobutyl chloroformate / acetonitrile / -15 °C 2: ammonium hydroxide / methanol 3: hydrogen; palladium on activated charcoal 4: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 5: zinc dibromide / dichloromethane / 12 h / 20 °C 6: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme | |
Multi-step reaction with 7 steps 1.1: 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine / dichloromethane / 0 - 20 °C / Large scale 1.2: -10 - 20 °C / Large scale 2.1: lithium hydroxide; water / tetrahydrofuran / 20 °C 3.1: 4-methyl-morpholine; isobutyl chloroformate / dichloromethane 3.2: 20 °C 4.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 5.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 6.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 7.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme | |
Multi-step reaction with 7 steps 1.1: 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine / dichloromethane / 0 - 20 °C / Large scale 1.2: -10 - 20 °C / Large scale 2.1: lithium hydroxide; water / tetrahydrofuran / 20 °C 3.1: triethylamine / dichloromethane / 20 °C 3.2: 20 °C 4.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 5.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 6.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 7.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
(S)-benzyl 2-((S)-2-(methoxycarbonyl)pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: lithium hydroxide; water / tetrahydrofuran / 18 h / 20 - 30 °C / Industrial scale 2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 0.5 h / -5 - 5 °C / Industrial scale 2.2: 22 h / -5 - 30 °C / Industrial scale 3.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 4.2: -5 - 35 °C / Industrial scale 5.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 6 steps 1.1: lithium hydroxide; water / tetrahydrofuran / 20 °C 2.1: 4-methyl-morpholine; isobutyl chloroformate / dichloromethane 2.2: 20 °C 3.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 4.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 5.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 6.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme | |
Multi-step reaction with 6 steps 1.1: lithium hydroxide; water / tetrahydrofuran / 20 °C 2.1: triethylamine / dichloromethane / 20 °C 2.2: 20 °C 3.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 4.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 5.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 6.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
Cbz-Pro-Pro-OH
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 0.5 h / -5 - 5 °C / Industrial scale 1.2: 22 h / -5 - 30 °C / Industrial scale 2.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale 3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / ethanol / -5 - 0 °C / Industrial scale 3.2: -5 - 35 °C / Industrial scale 4.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / 2327.23 - 3102.97 Torr / Industrial scale View Scheme | |
Multi-step reaction with 5 steps 1.1: 4-methyl-morpholine; isobutyl chloroformate / dichloromethane 1.2: 20 °C 2.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 3.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 4.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 5.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme | |
Multi-step reaction with 5 steps 1.1: triethylamine / dichloromethane / 20 °C 1.2: 20 °C 2.1: hydrogenchloride; hydrogen; palladium 10% on activated carbon / water; ethanol / 20 °C / 2327.23 - 3102.97 Torr 3.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / ethanol / -5 - 20 °C 4.1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 5.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 1H-imidazole; pivaloyl chloride / tetrahydrofuran; dichloromethane / -20 - -15 °C / Inert atmosphere 2: palladium on activated charcoal; triethylsilane / ethanol / 0 - 10 °C 3: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 4: zinc dibromide / dichloromethane / 12 h / 20 °C 5: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: palladium on activated charcoal; triethylsilane / ethanol / 0 - 10 °C 2: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 3: zinc dibromide / dichloromethane / 12 h / 20 °C 4: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: ammonium hydroxide / methanol 2: hydrogen; palladium on activated charcoal 3: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 4: zinc dibromide / dichloromethane / 12 h / 20 °C 5: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: hydrogen; palladium on activated charcoal 2: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 3: zinc dibromide / dichloromethane / 12 h / 20 °C 4: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: tert-butylamine; Octanethiol / 0.5 h / 20 °C 2: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 3: zinc dibromide / dichloromethane / 12 h / 20 °C 4: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: sodium hydroxide / water; N,N-dimethyl-formamide 2: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 3: zinc dibromide / dichloromethane / 12 h / 20 °C 4: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 2: zinc dibromide / dichloromethane / 12 h / 20 °C 3: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 4-methyl-morpholine; pivaloyl chloride / N,N-dimethyl-formamide / -15 - 20 °C / Inert atmosphere 2: zinc dibromide / dichloromethane / 12 h / 20 °C 3: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: zinc dibromide / dichloromethane / 12 h / 20 °C 2: tert-butylamine; Octanethiol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogenchloride / dichloromethane; tetrahydrofuran; water / 0 - 5 °C 2: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 2250.23 - 3000.3 Torr / Large scale View Scheme |
di-tert-butyl dicarbonate
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With triethylamine In 1,4-dioxane at 20℃; for 16h; | 90% |
2-Hydroxybenzophenone
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 48h; | 32% |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / 1,4-dioxane / 16 h / 20 °C 2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / tetrahydrofuran / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylamine / 1,4-dioxane / 16 h / 20 °C 2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / tetrahydrofuran / 20 °C 3: Grubbs catalyst first generation / dichloromethane / 72 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: triethylamine / 1,4-dioxane / 16 h / 20 °C 2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / tetrahydrofuran / 20 °C 3: Grubbs catalyst first generation / dichloromethane / 72 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / methanol / 18 h / 20 °C View Scheme |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: triethylamine / 1,4-dioxane / 16 h / 20 °C 2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / tetrahydrofuran / 20 °C 3: Grubbs catalyst first generation / dichloromethane / 72 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / methanol / 18 h / 20 °C 5: hydrogenchloride / methanol; dichloromethane / 2 h / 0 - 20 °C View Scheme |
1-hexadecylcarboxylic acid
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0 - 20℃; for 12h; | 20 mg |
L-Tartaric acid
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
In methanol at 20℃; for 0.75h; |
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 20℃; |
acetic acid
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
at 20℃; for 0.5h; |
succinic acid
benzyl (S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2 carbonyl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
In methanol at 20℃; for 0.75h; |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View