Products

Refine

Country

Business Type

Certificate

Display

Hangzhou Think Chemical Co. Ltd

3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic acid CAS No.:119736-16-2 Name: 3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic acid Synonyms:

High purity 3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic acid CAS No.:119736-16-2

Cas:119736-16-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 119736-16-2 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid Manufacturer

Cas:119736-16-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

High purity CAS 119736-16-2 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid in stock Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

High purity CAS 119736-16-2 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid in stock

Cas:119736-16-2

Min.Order:1 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New arrival CAS 119736-16-2 with best price

Cas:119736-16-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Product Detail Minimum Order Qty.

Factory Golden product 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid, CAS119736-16-2, C13H10O5

Cas:119736-16-2

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:119736-16-2

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

CAS119736-16-2 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Metric Ton

FOB Price: $11000.0 / 12000.0

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Aripiprazole Intermediate Transportation:Common products:Sea/Air/Courier Dangerous Chem:Se

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3-(BENZYLOXY)-4-OXO-4H-PYRAN-2-CARBOXYLIC ACID

Cas:119736-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our products mainly developing direction is "the best quality, the best service". In recent years, with the frequently international trading, which are sold well in Europe, America, Japan, Southeast Asia, more than 40 countries and regions,

High Purity 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Gram

FOB Price: $10.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid,119736-16-2

Cas:119736-16-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid Synonyms: 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid;4-oxo-3-((phenylmethyl)oxy)-4h-pyran-2-carboxylic acid;4-Oxo-3-(phenylmethoxy)-4H-pyran-2-carboxylic acid;4-oxo-3-phenylmethox

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid,119736-16-2

Cas:119736-16-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid,119736-16-2

Cas:119736-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Factory Golden product 3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid, CAS119736-16-2, C13H10O5 CAS NO.119736-16-2

Cas:119736-16-2

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid,119736-16-2

Cas:119736-16-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid cas no. 119736-16-2 98%

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid

Cas:119736-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-Appearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acid,119736-16-2

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4H-Pyran-2-carboxylic acid, 4-oxo-3-(phenylmethoxy)-

Cas:119736-16-2

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

3-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde
500371-01-7

3-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With sodium hypochlorite; aminosulfonic acid In water; acetone at 20℃; for 2h;97%
With sodium chlorite; aminosulfonic acid In water; acetone at 20℃; Cooling with ice;88%
With sodium chlorite; aminosulfonic acid In water; acetone at 20℃; Cooling;86%
2-(hydroxymethyl)-3-(phenylmethoxy)-4H-pyran-4-one
119736-15-1

2-(hydroxymethyl)-3-(phenylmethoxy)-4H-pyran-4-one

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With palladium on activated charcoal; oxygen; sodium hydroxide In water at 60℃; under 7600.51 Torr; Autoclave; Green chemistry;92%
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide In dichloromethane; water at 5℃; for 1h; Solvent; Reagent/catalyst; Temperature; Large scale;83%
With jones reagent19%
C16H17NO3

C16H17NO3

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With sodium periodate In water83.5%
Stage #1: C16H17NO3 With sodium periodate; water In N,N-dimethyl-formamide at 25℃; for 0.5h;
Stage #2: With sodium chlorite; aminosulfonic acid; water In N,N-dimethyl-formamide; acetone at 25℃; for 1h;
82%
Multi-step reaction with 2 steps
1: sodium periodate / water; acetone / 5.27 h / 20 °C / Inert atmosphere; Cooling with ice
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium hypochlorite / water; acetonitrile / 2.63 h / 20 °C / Inert atmosphere; Cooling with ice
View Scheme
3-O-benzylmaltol
61049-69-2

3-O-benzylmaltol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With chromium(VI) oxide; periodic acid In acetonitrile at 20℃; for 1.5h;71%
Multi-step reaction with 2 steps
1: SeO2 / various solvent(s) / 155 °C
2: NaClO2; NH2SO3H / acetone; H2O
View Scheme
Multi-step reaction with 2 steps
1: SeO2 / various solvent(s) / 12 h / 160 °C
2: NaClO2; aq. H2O2; NaH2PO4 / acetonitrile / 1 h / 20 °C
View Scheme
C20H16O3
1229006-11-4

C20H16O3

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: C20H16O3 With sodium periodate; sulfuric acid; rhodium(III) chloride hydrate In water; acetonitrile at 20℃; for 3.5h;
Stage #2: With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate In ethyl acetate at 25℃; for 1.5h; Product distribution / selectivity;
70%
Stage #1: C20H16O3 With sodium periodate; rhodium(III) chloride hydrate; sulfuric acid In water; acetonitrile at 20℃; for 3.5h;
Stage #2: With sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate In water; acetonitrile at 25℃; for 1.5h; Reagent/catalyst;
70%
Stage #1: C20H16O3 With ruthenium trichloride; sodium periodate
Stage #2: With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical
70%
2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one
1206102-05-7

2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one With sodium periodate; rhodium(III) chloride hydrate; water In ethyl acetate; acetonitrile at 25℃; for 1h;
Stage #2: With sodium chlorite In ethyl acetate; acetonitrile at 25℃; for 1h;
56%
Stage #1: 2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one With sodium periodate; rhodium(III) chloride hydrate In water; ethyl acetate; acetonitrile at 25℃; for 1h;
Stage #2: With sodium chlorite In water; ethyl acetate; acetonitrile at 25℃; for 1h;
56%
Stage #1: 2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one With ruthenium trichloride; sodium periodate In water; ethyl acetate; acetonitrile at 15℃; for 2h; Inert atmosphere;
Stage #2: With sodium chlorite In water; ethyl acetate; acetonitrile at 20℃; for 2h;
52%
Multi-step reaction with 2 steps
1: ruthenium trichloride; sodium periodate; sulfuric acid / acetonitrile; water / 20 °C / Large scale
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium hypochlorite / acetonitrile; water; ethyl acetate / 20 °C / Large scale
View Scheme
Maltol
118-71-8

Maltol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 83 percent / aq. NaOH / methanol / 75 °C
2: SeO2 / various solvent(s) / 155 °C
3: NaClO2; NH2SO3H / acetone; H2O
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / methanol / 8 h / Reflux
2: selenium(IV) oxide / 14 h / 159 °C
3: sodium hypochlorite; aminosulfonic acid / water; acetone / 2 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / Inert atmosphere; Reflux; Large scale
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -60 °C / Inert atmosphere
2.2: 2 h / -60 °C / Inert atmosphere
3.1: triethylamine; methanesulfonyl chloride / dichloromethane / 2 h / -30 °C / Inert atmosphere
3.2: 0.33 h / 0 °C
4.1: ruthenium trichloride; sodium periodate / acetonitrile; ethyl acetate; water / 2 h / 15 °C / Inert atmosphere
4.2: 2 h / 20 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

ZnCr-benzoate*3H2O

ZnCr-benzoate*3H2O

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 83 percent / aq. NaOH / methanol / 75 °C
2: SeO2 / various solvent(s) / 155 °C
3: NaClO2; NH2SO3H / acetone; H2O
View Scheme
benzyl chloride
100-44-7

benzyl chloride

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / methanol / 8 h / Reflux
2: selenium(IV) oxide / 14 h / 159 °C
3: sodium hypochlorite; aminosulfonic acid / water; acetone / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
2: aminosulfonic acid; sodium hypochlorite
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / methanol / 1 h / Reflux
2: periodic acid; chromium(VI) oxide / acetonitrile / 1.5 h / 20 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / Inert atmosphere; Reflux; Large scale
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -60 °C / Inert atmosphere
2.2: 2 h / -60 °C / Inert atmosphere
3.1: triethylamine; methanesulfonyl chloride / dichloromethane / 2 h / -30 °C / Inert atmosphere
3.2: 0.33 h / 0 °C
4.1: ruthenium trichloride; sodium periodate / acetonitrile; ethyl acetate; water / 2 h / 15 °C / Inert atmosphere
4.2: 2 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / 5 h / 80 °C
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -60 °C
2.2: 1 h / -60 °C
3.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 30 °C
3.2: 0.5 h / 30 °C
4.1: sodium periodate; rhodium(III) chloride hydrate; water / acetonitrile; ethyl acetate / 1 h / 25 °C
4.2: 1 h / 25 °C
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 5 h / 13 - 80 °C / Large scale
2: bromobenzene; selenium(IV) oxide / 13 h / 140 °C / Dean-Stark
3: sodium chlorite; aminosulfonic acid / water; acetone / 0.67 h / 20 °C / Cooling with ice
View Scheme
2-(2-hydroxy-2-phenylethyl)-3-[(phenylmethyl)oxy]-4H-pyran-4-one
1206102-04-6

2-(2-hydroxy-2-phenylethyl)-3-[(phenylmethyl)oxy]-4H-pyran-4-one

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine; methanesulfonyl chloride / dichloromethane / 2 h / -30 °C / Inert atmosphere
1.2: 0.33 h / 0 °C
2.1: ruthenium trichloride; sodium periodate / acetonitrile; ethyl acetate; water / 2 h / 15 °C / Inert atmosphere
2.2: 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 30 °C
1.2: 0.5 h / 30 °C
2.1: sodium periodate; rhodium(III) chloride hydrate; water / acetonitrile; ethyl acetate / 1 h / 25 °C
2.2: 1 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 0.5 h / 30 °C
2.1: rhodium(III) chloride hydrate; sodium periodate; sulfuric acid / water; acetonitrile / 3.5 h / 20 °C
2.2: 1.5 h / 25 °C
View Scheme
C21H20O6S

C21H20O6S

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 0.5 h / 30 °C
2.1: sodium periodate / rhodium(III) chloride hydrate / water; ethyl acetate; acetonitrile / 1 h / 25 °C
2.2: 1 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 1,8-diazabicyclo[5.4.0]undec-7-ene
2: ruthenium trichloride; sodium periodate
View Scheme
3-hydroxy-pyran-4-one
496-63-9

3-hydroxy-pyran-4-one

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium hydroxide / water; methanol / 1 h / 5 °C / Large scale
1.2: 24 h / 5 - 20 °C / Large scale
2.1: sodium hydroxide / water; methanol / 3 h / 70 °C / Large scale
3.1: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / water; dichloromethane / 1 h / 5 °C / Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide / water; methanol / 1 h / 5 °C / Large scale
1.2: 24 h / 5 - 20 °C / Large scale
2.1: potassium carbonate / methanol / 2 h / 70 °C / Large scale
3.1: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / water; dichloromethane / 1 h / 5 °C / Large scale
View Scheme
(2-furyl)methyl alcohol
98-00-0

(2-furyl)methyl alcohol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium acetate; chlorine / ethanol; water / 5 °C / Large scale
2.1: sodium hydroxide / water; methanol / 1 h / 5 °C / Large scale
2.2: 24 h / 5 - 20 °C / Large scale
3.1: sodium hydroxide / water; methanol / 3 h / 70 °C / Large scale
4.1: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / water; dichloromethane / 1 h / 5 °C / Large scale
View Scheme
Multi-step reaction with 4 steps
1.1: sodium acetate; chlorine / ethanol; water / 5 °C / Large scale
2.1: sodium hydroxide / water; methanol / 1 h / 5 °C / Large scale
2.2: 24 h / 5 - 20 °C / Large scale
3.1: potassium carbonate / methanol / 2 h / 70 °C / Large scale
4.1: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / water; dichloromethane / 1 h / 5 °C / Large scale
View Scheme
2-Hydroxymethyl-3-hydroxy-pyran-4(1H)-one
1968-51-0

2-Hydroxymethyl-3-hydroxy-pyran-4(1H)-one

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / water; methanol / 3 h / 70 °C / Large scale
2: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / water; dichloromethane / 1 h / 5 °C / Large scale
View Scheme
Multi-step reaction with 3 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; sodium hypochlorite / dichloromethane; water / 0.5 h / 0 - 10 °C / Large scale
2: sodium hydroxide / water; methanol / 4 h / 25 - 55 °C / Large scale
3: sodium hydroxide / water; methanol / 4 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; sodium hypochlorite / dichloromethane; water / 0.5 h / 0 - 10 °C / Large scale
2: potassium hydroxide / water; methanol / 4 h / 25 - 55 °C
3: sodium hydroxide / water; methanol / 4 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; sodium hypochlorite / dichloromethane; water / 0.5 h / 0 - 10 °C / Large scale
2: potassium carbonate / water; ethanol / 4 h / 25 - 55 °C
3: sodium hydroxide / water; methanol / 4 h / 30 °C
View Scheme
2-methyl-4-oxo-4H-pyran-3-yl acetate
28787-36-2

2-methyl-4-oxo-4H-pyran-3-yl acetate

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / 1,2-dichloro-ethane / 7 h / 60 °C / Green chemistry
2.1: sodium hydroxide / water / 2 h / Reflux; Green chemistry
2.2: 3 h / Reflux; Green chemistry
3.1: sodium hydroxide; palladium on activated charcoal; oxygen / water / 60 °C / 7600.51 Torr / Autoclave; Green chemistry
View Scheme
3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid

3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / water; methanol / 4 h / 25 - 55 °C / Large scale
2: sodium hydroxide / water; methanol / 4 h / 30 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium hydroxide / water; methanol / 4 h / 25 - 55 °C
2: sodium hydroxide / water; methanol / 4 h / 30 °C
View Scheme
C20H16O5

C20H16O5

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol; water at 30℃; for 4h; Temperature; Reagent/catalyst;6.9 g
dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate
1246616-66-9

dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; water at 100℃; for 5h; Reagent/catalyst; Temperature;10.9 g
benzyl alcohol
100-51-6

benzyl alcohol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium t-butanolate / tetrahydrofuran / 1 h / 10 - 20 °C / Cooling with ice
1.2: 20 °C
2.1: 1 h / 50 - 60 °C
3.1: sodium t-butanolate / tetrahydrofuran / 2.17 h / 0 - 30 °C / Inert atmosphere; Cooling with ice
4.1: hydrogenchloride; water / 5 h / 100 °C
View Scheme
4-benzyloxy-3-oxobutyric acid methyl ester
82961-76-0

4-benzyloxy-3-oxobutyric acid methyl ester

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1 h / 50 - 60 °C
2: sodium t-butanolate / tetrahydrofuran / 2.17 h / 0 - 30 °C / Inert atmosphere; Cooling with ice
3: hydrogenchloride; water / 5 h / 100 °C
View Scheme
(R)-1-pyrrolidin-2-ylmethylcarbamic acid tert-butyl ester
719999-54-9

(R)-1-pyrrolidin-2-ylmethylcarbamic acid tert-butyl ester

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C23H28N2O6
1309561-94-1

C23H28N2O6

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran for 16h;100%
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid hydrochloride
1246617-42-4

3-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid hydrochloride

Conditions
ConditionsYield
With ammonium hydroxide at 20℃; for 12h;100%
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With ammonia In water at 20℃; for 12h;
Stage #2: With hydrogenchloride In water
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With ammonium hydroxide at 20℃;
Stage #2: With hydrogenchloride In water
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid

3-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Conditions
ConditionsYield
With ammonia In water at 20℃; for 12h;100%
With ammonium hydroxide In water at 20℃; for 16h;
With ammonium hydroxide In water at 20℃; for 16h;
With ammonium hydroxide In water at 20℃; for 16h;
With ammonium hydroxide In water at 25℃;
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

ethyl iodide
75-03-6

ethyl iodide

ethyl 3-(benzyloxy)-4-oxo-4H- pyran-2-formate
1332855-94-3

ethyl 3-(benzyloxy)-4-oxo-4H- pyran-2-formate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-d6-formamide at 20℃;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃;100%
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C15H11F3O5

C15H11F3O5

Conditions
ConditionsYield
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 5h; Cooling with ice;
Stage #2: 2,2,2-trifluoroethanol With dmap; triethylamine In dichloromethane at 20℃; for 1h; Cooling with ice;
100%
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 5h;
Stage #2: 2,2,2-trifluoroethanol With dmap; triethylamine In dichloromethane at 20℃; for 1h; Cooling with ice;
100%
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With potassium carbonate In acetone at 20℃;
Stage #2: dimethyl sulfate In acetone at 20 - 55℃; Temperature;
98%
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 20℃; for 14.5h;94%
With sodium hydrogencarbonate In N,N-dimethyl acetamide at 25℃; for 7h;
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C17H19NO6

C17H19NO6

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide for 24h;94.71%
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

methyl iodide
74-88-4

methyl iodide

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; Cooling with ice;90%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 10h;89%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 20h;69%
With sodium hydrogencarbonate In 1-methyl-pyrrolidin-2-one for 16h; Heating;
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C13H11NO5

C13H11NO5

Conditions
ConditionsYield
With hydroxylamine hydrochloride In methanol; water for 10h; Reflux;90%
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

methylamine
74-89-5

methylamine

3-(benzyloxy)-N-methyl-4-oxo-4H-pyran-2-carboxamide

3-(benzyloxy)-N-methyl-4-oxo-4H-pyran-2-carboxamide

Conditions
ConditionsYield
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 5.5h;
Stage #2: methylamine In tetrahydrofuran at 20℃;
86%
3-Amino-1,2-propanediol
616-30-8, 13552-31-3

3-Amino-1,2-propanediol

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

1-(2,3-dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic acid
1206102-06-8

1-(2,3-dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic acid

Conditions
ConditionsYield
In ethanol for 1h; Reflux;85%
In ethanol at 65 - 80℃; for 8.5h; Product distribution / selectivity;83%
With pyridine In ethanol at 65 - 80℃; for 8.5h;83%
ethanamine hydrochloride
557-66-4

ethanamine hydrochloride

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C15H15NO4

C15H15NO4

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 1h;80%
C11H22N2O2*ClH

C11H22N2O2*ClH

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C24H30N2O6

C24H30N2O6

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h;78%
C33H63N7O9

C33H63N7O9

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

C72H87N7O21

C72H87N7O21

Conditions
ConditionsYield
With dmap; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;34%
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With methanol at 20℃;
In tetrahydrofuran; methanol; hexane at 20℃; for 1.5h; Cooling with ice;
1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester
1037293-71-2

3-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
Stage #1: 1-hydroxy-pyrrolidine-2,5-dione; 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 3h;
With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 3.5h;
With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 5h;
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

TRENMAN
880763-30-4

TRENMAN

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tetrahydrofuran / 0.5 h / 20 °C
1.2: DCC / tetrahydrofuran / 3 h / 20 °C
2.1: 2.7 g / tetrahydrofuran / 20 °C
3.1: aq. HCl; AcOH / 24 h / 20 °C
View Scheme
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

N,N',N''-(nitrilotris(ethane-2,1-diyl))tris(3-(benzyloxy)-4-oxo-4H-pyran-2-carboxamide)
880763-29-1

N,N',N''-(nitrilotris(ethane-2,1-diyl))tris(3-(benzyloxy)-4-oxo-4H-pyran-2-carboxamide)

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 0.5 h / 20 °C
1.2: DCC / tetrahydrofuran / 3 h / 20 °C
2.1: 2.7 g / tetrahydrofuran / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide / tetrahydrofuran / 3.5 h / 20 °C
2: tetrahydrofuran / 20 °C
View Scheme
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: MeOH / 20 °C
2: aq. HCl / 6 h / Heating
View Scheme
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid

3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: MeOH / 20 °C
2: aq. HCl / 6 h / Heating
3: NaOH / methanol / 20 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-benzyloxy-5-bromo-4-oxo-4H-pyrane-2-carboxylic acid methyl ester
500371-73-3

3-benzyloxy-5-bromo-4-oxo-4H-pyrane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid; diazomethyl-trimethyl-silane In tetrahydrofuran; methanol; hexane at 0 - 20℃; for 1.5h;
Stage #2: With bromine In chloroform at 75℃; for 48h;
Stage #3: benzyl bromide With potassium carbonate In DMF (N,N-dimethyl-formamide) at 80℃;
4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
119736-16-2

4-oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic acid

3-(benzyloxy)-4-oxo-4H-pyran-2-carbonyl chloride
845724-16-5

3-(benzyloxy)-4-oxo-4H-pyran-2-carbonyl chloride

Conditions
ConditionsYield
With oxalyl dichloride; N,N-dimethyl-formamide In chloroform at 20℃; for 0.5h;
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 0.5h;
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 5h; Cooling with ice;

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View