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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-(2-Bromoethyl)-2-Oxoindole supplier in China

Cas:120427-96-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

4-(2-Bromoethyl)-2-oxoindole CAS No.:120427-96-5 Name: 4-(2-Bromoethyl)-2-oxoindole Synonyms: 4-(2-Bromoethyl)indolin-2-one; 4-(2-Bromoethyl)-1,3-dihydro-2H-indol-2-one Molecular St

High purity 4-(2-Bromoethyl)-2-oxoindole CAS No.:120427-96-5

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-(2-Bromoethyl)-2-Oxoindole

Cas:120427-96-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-(2-BroMoethyl)-1,3-dihydro-2H-indolin-2-one CAS 120427-96-5

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 120427-96-5 with competitive price

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Chemical Name 4-(2-Bromoethyl)-2-oxoindole Synonyms 4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE; CAS No. 120427-96-5 Molecular Formula C10H10BrNO

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE

Cas:120427-96-5

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

CAS 120427-96-5 4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-(2-Bromoethyl)-2-oxoindole 120427-96-5

Cas:120427-96-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-(2-Bromoethyl)-1,3-Dihydro-2H-Indol-2-One

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Other

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Light Yellow crystal Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Inte

4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE

Cas:120427-96-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 4-(2'-BROMOETHYL)-1,3-DIHYDRO-2H-INDOLE-2-ONE

Cas:120427-96-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-(2'-Bromoethyl)-1,3-dihydro-2-indoline-2-one

Cas:120427-96-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-(2-Bromoethyl)-2-oxoindole cas no. 120427-96-5 95%

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-(2'-Bromoethyl)-1,3-Dihydro-2H-Indole-2-One

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Other

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

Best price 4-(2-Bromoethyl)-2-Oxoindole 120427-96-5

Cas:120427-96-5

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-(2-Bromoethyl)-2-oxoindole

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

4-(2-Bromoethyl)-1,3-Dihydro-2H-Indol-2-One

Cas:120427-96-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4-(2-Bromoethyl)-2-Oxoindole

Cas:120427-96-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
120427-95-4

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With sodium hypophosphite; palladium on activated charcoal In ethyl acetate for 0.583333h; Heating;95%
With sodium hypophosphite monohydrate; palladium on activated charcoal In water; ethyl acetate Large scale;95%
With sodium hypophosphite hydrate; palladium 10% on activated carbon In water; ethyl acetate for 1h; Heating / reflux;88.97%
With phosphonic Acid; sodium iodide In ethanol at 70℃; for 5h; Reagent/catalyst;86.7%
2-(2-bromoethyl)benzaldehyde
22901-09-3

2-(2-bromoethyl)benzaldehyde

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / MeONa / methanol / 1 h / 0 °C
2: 53 percent / AcCl, FeCl3 / CH2Cl2 / 3 h / 0 - 5 °C
3: 95 percent / aq. NaH2PO2 / 10percent Pd-C / ethyl acetate / 0.58 h / Heating
View Scheme
2-(2-bromoethyl)-β-nitrostyrene

2-(2-bromoethyl)-β-nitrostyrene

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 53 percent / AcCl, FeCl3 / CH2Cl2 / 3 h / 0 - 5 °C
2: 95 percent / aq. NaH2PO2 / 10percent Pd-C / ethyl acetate / 0.58 h / Heating
View Scheme
sodium phosphinate hydrate

sodium phosphinate hydrate

pyrographite
7440-44-0

pyrographite

palladium
7440-05-3

palladium

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
120427-95-4

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
In water
sodium phosphinate hydrate

sodium phosphinate hydrate

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
120427-95-4

4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
carbon palladium In water17.0 g (82%)
isochromane
493-05-0

isochromane

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: bromine / water / Irradiation
2: water; methanol / Acidic conditions; Large scale
3: iron(III) chloride / Acidic conditions; Large scale
4: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale
View Scheme
Multi-step reaction with 7 steps
1: zinc(II) chloride / dichloromethane / Reflux
2: hexamethylenetetramine; acetic acid / ethanol; water
3: N-butylamine; acetic acid; nitromethane / methanol / 20 °C
4: iron(III) chloride / dichloromethane / 0 - 5 °C
5: hydrazine hydrate; palladium 10% on activated carbon / methanol
6: sodium hydroxide; water / methanol / Reflux
7: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
1-Bromoisochromane
50683-32-4

1-Bromoisochromane

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; methanol / Acidic conditions; Large scale
2: iron(III) chloride / Acidic conditions; Large scale
3: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale
View Scheme
2-(2-bromoethyl)-β-nitrostyrene

2-(2-bromoethyl)-β-nitrostyrene

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iron(III) chloride / Acidic conditions; Large scale
2: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale
View Scheme
4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one
139122-17-1

4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrazine hydrate; palladium 10% on activated carbon / methanol
2: sodium hydroxide; water / methanol / Reflux
3: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
4-(2-benzoyloxyethyl)-1,3-dihydro-2H-indolin-2-one
139122-18-2

4-(2-benzoyloxyethyl)-1,3-dihydro-2H-indolin-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; water / methanol / Reflux
2: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
4-(2'-hydroxyethyl)-1,3-dihydro-2H-indol-2-one
139122-19-3

4-(2'-hydroxyethyl)-1,3-dihydro-2H-indol-2-one

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With carbon tetrabromide; triphenylphosphine In dichloromethane at 0 - 20℃;
2-(2-methyl-3-nitrophenyl)acetic acid
23876-15-5

2-(2-methyl-3-nitrophenyl)acetic acid

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: borane-THF / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
2.2: 8 h / 20 °C / Inert atmosphere
3.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h / 0 °C / Inert atmosphere
3.2: 8 h / 20 °C / Inert atmosphere
4.1: sodium hydroxide / tetrahydrofuran / 0.17 h / 0 °C
4.2: 1 h / 20 °C / pH 1.5
5.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 20 °C
6.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
2-[2-(chloromethyl)phenyl]ethylbenzoate
168476-58-2

2-[2-(chloromethyl)phenyl]ethylbenzoate

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: hexamethylenetetramine; acetic acid / ethanol; water
2: N-butylamine; acetic acid; nitromethane / methanol / 20 °C
3: iron(III) chloride / dichloromethane / 0 - 5 °C
4: hydrazine hydrate; palladium 10% on activated carbon / methanol
5: sodium hydroxide; water / methanol / Reflux
6: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
2-(2-methyl-3-nitrophenyl)ethyl alcohol
855382-76-2

2-(2-methyl-3-nitrophenyl)ethyl alcohol

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 8 h / 20 °C / Inert atmosphere
2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h / 0 °C / Inert atmosphere
2.2: 8 h / 20 °C / Inert atmosphere
3.1: sodium hydroxide / tetrahydrofuran / 0.17 h / 0 °C
3.2: 1 h / 20 °C / pH 1.5
4.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 20 °C
5.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
1-[(2-methyl-3-nitrophenethyloxy)methyl]benzene
1426679-26-6

1-[(2-methyl-3-nitrophenethyloxy)methyl]benzene

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h / 0 °C / Inert atmosphere
1.2: 8 h / 20 °C / Inert atmosphere
2.1: sodium hydroxide / tetrahydrofuran / 0.17 h / 0 °C
2.2: 1 h / 20 °C / pH 1.5
3.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 20 °C
4.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
ethyl 3-[2-[2-(benzyloxy)ethyl]-6-nitrophenyl]-2-oxopropanoate
1441070-77-4

ethyl 3-[2-[2-(benzyloxy)ethyl]-6-nitrophenyl]-2-oxopropanoate

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium hydroxide / tetrahydrofuran / 0.17 h / 0 °C
1.2: 1 h / 20 °C / pH 1.5
2.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 20 °C
3.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
2-[2-[2-(benzyloxy)ethyl]-6-nitrophenyl]acetic acid
1426679-27-7

2-[2-[2-(benzyloxy)ethyl]-6-nitrophenyl]acetic acid

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 20 °C
2: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
benzoic acid (2-formyl)phenethyl ester
139122-15-9

benzoic acid (2-formyl)phenethyl ester

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: N-butylamine; acetic acid; nitromethane / methanol / 20 °C
2: iron(III) chloride / dichloromethane / 0 - 5 °C
3: hydrazine hydrate; palladium 10% on activated carbon / methanol
4: sodium hydroxide; water / methanol / Reflux
5: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
benzoic acid (2-(2-nitroethenyl))phenethyl ester
139122-16-0

benzoic acid (2-(2-nitroethenyl))phenethyl ester

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: iron(III) chloride / dichloromethane / 0 - 5 °C
2: hydrazine hydrate; palladium 10% on activated carbon / methanol
3: sodium hydroxide; water / methanol / Reflux
4: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C
View Scheme
sodium acetate
127-09-3

sodium acetate

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

4-(2-acetoxyethyl)-1,3-dihydro-2H-indolin-2-one
168476-61-7

4-(2-acetoxyethyl)-1,3-dihydro-2H-indolin-2-one

Conditions
ConditionsYield
In ethanol; water for 24h; Heating;89%
di-n-propylamine
142-84-7

di-n-propylamine

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

A

ropinirole hydrochloride
91374-20-8

ropinirole hydrochloride

B

4-ethylenyl-1,3-dihydro-2H-indol-2-one

4-ethylenyl-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With hydrogenchloride In water Large scale;A 57%
B 38%
di-n-propylamine
142-84-7

di-n-propylamine

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

ropinirole hydrochloride
91374-20-8

ropinirole hydrochloride

Conditions
ConditionsYield
Stage #1: di-n-propylamine; 4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one In water; acetonitrile at 65 - 70℃; for 1.25h;
Stage #2: With hydrogenchloride In water pH=2;
50%
propylamine
107-10-8

propylamine

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

A

4-ethylenyl-1,3-dihydro-2H-indol-2-one

4-ethylenyl-1,3-dihydro-2H-indol-2-one

B

N-Despropylropinirole

N-Despropylropinirole

Conditions
ConditionsYield
Reflux;A 35%
B 45%
di-n-propylamine
142-84-7

di-n-propylamine

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

A

Ropinirole
91374-21-9

Ropinirole

B

4-ethylenyl-1,3-dihydro-2H-indol-2-one

4-ethylenyl-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
In water for 2.5h; Heating;A n/a
B 38%
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

Ropinirole
91374-21-9

Ropinirole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 87 percent / pyridine / CH2Cl2 / 4 h / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

4-ethylenyl-1,3-dihydro-2H-indol-2-one

4-ethylenyl-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 87 percent / pyridine / CH2Cl2 / 4 h / 5 - 10 °C
4: H2O / 2 h / Heating
View Scheme
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

4-(2'-hydroxyethyl)-1,3-dihydro-2H-indol-2-one
139122-19-3

4-(2'-hydroxyethyl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
View Scheme
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

2-(2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl methanesulfonate
139122-21-7

2-(2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl methanesulfonate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
View Scheme
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

2-(2'-oxo-2,3-dihydro-4-indolyl)ethyl benzenesulphonate
139122-22-8

2-(2'-oxo-2,3-dihydro-4-indolyl)ethyl benzenesulphonate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C
View Scheme
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
120427-96-5

4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one

2-(2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl-4-methylbenzene-1-sulfonate
139122-20-6

2-(2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl-4-methylbenzene-1-sulfonate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / ethanol; H2O / 24 h / Heating
2: 70 percent / aq. HCl / 2.5 h / Heating
3: 87 percent / pyridine / CH2Cl2 / 4 h / 5 - 10 °C
View Scheme

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