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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-(2-(7-CHLOROQUINOLIN-2-YL)VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(E)-3-[2-[7-Chloro-2-quinolinyl)-vinyl]-benzaldehyde

Cas:120578-03-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzaldehyde,3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]- 120578-03-2

Cas:120578-03-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE CAS: 120578-03-2 MF: C18H12ClNO MW: 293.75 EINECS: 421-800-1 Mol File: 120578-03-2.mol 3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE Structure 3-(2-(7-CHLOR

3-[2-(7-Chloro-2-quinolinyl)-(E)-etheyl]benzaldehyde

Cas:120578-03-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE CAS:120578-03-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, speciali

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE CAS:120578-03-2

Cas:120578-03-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzaldehyde,3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]-

Cas:120578-03-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzaldehyde,3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]-

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE CAS:120578-03-2

Cas:120578-03-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-(2-(7-Chloroquinoline-2-yl)-(E)-vinyl)benzaldehyde

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-(2-(7-chloroquinoline-2-yl)-(e)-vinyl)benzaldehyde

Cas:120578-03-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

TIANFU CHEM 120578-03-2 3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3-(2-(7-chloroquinoline-2-yl)-(e)-vinyl)benzaldehyde

Cas:120578-03-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Senova Technology Company Limited

high purity Application:Pharmaceutical Intermediate

3-[2-(7-chloro-2-quinolinyl) ethenyl]benzaldehyde

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

3-(2-(7-Chloroquinoline-2-yl)-(E)-vinyl)benzaldehyde

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-(2-(7-Chloroquinoline-2-yl)-(E)-vinyl)benzaldehyde

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

3-[2-(7-Chloro-2-Quinolinyl)-(E)-Etheyl]Benzaldehyde

Cas:120578-03-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Enterprise standard Application:Pharma Intermediate

Benzaldehyde,3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]-

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzaldehyde,3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]-

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

TIANFUCHEM--120578-03-2---C18H12ClNO Application:TIANFUCHEM--120578-03-2---C18H12ClNO

TIANFUCHEM--120578-03-2---C18H12ClNO

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

(E)-3-(2-(7-chloroquinolin-2-yl)vinyl)benzaldehyde CAS No.120578-03-2

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE

Cas:120578-03-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-methyl-7-chloroquinoline
4965-33-7

2-methyl-7-chloroquinoline

Isophthalaldehyde
626-19-7

Isophthalaldehyde

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

Conditions
ConditionsYield
With lanthanum pentafluorobenzoate In toluene at 120℃; for 24h;97%
With tert-butylammonium hexafluorophosphate(V); calcium(II) trifluoromethanesulfonate In neat (no solvent) at 130℃; Green chemistry;93%
With acetic anhydride In toluene at 100 - 105℃; for 12 - 15h;75.15%
2-methyl-7-chloroquinoline
4965-33-7

2-methyl-7-chloroquinoline

Isophthalaldehyde
626-19-7

Isophthalaldehyde

A

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

B

C28H18Cl2N2
120578-04-3

C28H18Cl2N2

Conditions
ConditionsYield
With acetic acid at 100℃; Product distribution / selectivity;A 65.45%
B 7.75%
With acetic anhydride In xylene for 7h; Heating; Yield given;
With acetic anhydride In xylene for 7h; Heating; Yields of byproduct given;
2-((S)-3-Acetoxy-1-bromo-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl)-benzoic acid methyl ester
184763-69-7

2-((S)-3-Acetoxy-1-bromo-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl)-benzoic acid methyl ester

A

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

B

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol
139425-04-0

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol

C

3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoic acid
203940-18-5

3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoic acid

D

2-((S)-1-Bromo-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-hydroxy-propyl)-benzoic acid
1026009-57-3

2-((S)-1-Bromo-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-hydroxy-propyl)-benzoic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran; methanol at 23℃; for 24h;
methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate
181139-72-0

methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / Et3N, 4-DMAP / CH2Cl2 / 0.25 h
2: 69 percent / NBS, (BzO)2 / CCl4 / 3 h / Heating
3: 1 N LiOH / tetrahydrofuran; methanol / 24 h / 23 °C
View Scheme
2-((S)-3-Acetoxy-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl)-benzoic acid methyl ester
184763-59-5

2-((S)-3-Acetoxy-3-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl)-benzoic acid methyl ester

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 69 percent / NBS, (BzO)2 / CCl4 / 3 h / Heating
2: 1 N LiOH / tetrahydrofuran; methanol / 24 h / 23 °C
View Scheme
2-methyl-7-chloroquinoline
4965-33-7

2-methyl-7-chloroquinoline

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

Conditions
ConditionsYield
In Isophthalaldehyde
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

ethylene glycol
107-21-1

ethylene glycol

2-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-1,3-dioxolane
143816-71-1

2-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-1,3-dioxolane

Conditions
ConditionsYield
In toluene Heating;98%
vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

A

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol
139425-04-0

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol

B

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol
149968-10-5

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol

Conditions
ConditionsYield
In tetrahydrofuran; toluene at 0 - 5℃; for 1h; Yields of byproduct given;A n/a
B 92%
vinylmagnesium chloride
3536-96-7

vinylmagnesium chloride

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol
149968-10-5

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol

Conditions
ConditionsYield
In tetrahydrofuran; ethylbenzene at -15℃;91%
Stage #1: vinylmagnesium chloride; (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde In tetrahydrofuran; toluene at 0 - 10℃; for 1.5h;
Stage #2: With ammonium acetate; water In tetrahydrofuran; toluene for 1h;
methylmagnesium chloride
676-58-4

methylmagnesium chloride

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

3-(7-Chloroquinol-2-yl-trans-ethenyl)-alpha-methylbenzyl alcohol
139425-24-4

3-(7-Chloroquinol-2-yl-trans-ethenyl)-alpha-methylbenzyl alcohol

Conditions
ConditionsYield
Stage #1: methylmagnesium chloride; (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde In tetrahydrofuran at -10 - 5℃; for 2.75h;
Stage #2: With water at 10 - 15℃; for 0.5h;
89.43%
In tetrahydrofuran; toluene at -10℃; for 2h; Inert atmosphere;78%
In tetrahydrofuran; toluene at -10℃; for 2h; Inert atmosphere;78%
Stage #1: methylmagnesium chloride; (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde In toluene at -5℃; for 2h;
Stage #2: With water; ammonium chloride In toluene at 5℃; for 2h; Product distribution / selectivity;
Methyl 3-mercaptopropionate
2935-90-2

Methyl 3-mercaptopropionate

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

dimethyl 5-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-4,6-dithianonanedioate
120385-96-8

dimethyl 5-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-4,6-dithianonanedioate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at -5 - 0℃; for 2h;87%
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

acetone
67-64-1

acetone

(E)-4-{3-[(E)-2-(7-chloroquinolin-2-yl)vinyl]phenyl}but-3-en-2-one
1429879-31-1

(E)-4-{3-[(E)-2-(7-chloroquinolin-2-yl)vinyl]phenyl}but-3-en-2-one

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; water for 3h;76.47%
With sodium hydroxide In tetrahydrofuran; water for 3h;76.47%
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

7-chloro-2-[(E)-2-(3-oxiranylphenyl)vinyl]quinoline
1429879-00-4

7-chloro-2-[(E)-2-(3-oxiranylphenyl)vinyl]quinoline

Conditions
ConditionsYield
With trimethylsulphonium iodide; sodium hydride In tetrahydrofuran; dimethyl sulfoxide for 2h; Inert atmosphere;66%
With trimethylsulphonium iodide; sodium hydride In tetrahydrofuran for 2h; Inert atmosphere;66%
Methyl 3-mercaptopropionate
2935-90-2

Methyl 3-mercaptopropionate

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

N,N-dimethyl-3-mercaptopropionamide
92065-71-9

N,N-dimethyl-3-mercaptopropionamide

(+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate
120443-15-4

(+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In chloroform at -8 - 2℃; for 2h;49%
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

ethyl bromoacetate
105-36-2

ethyl bromoacetate

ethyl 3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxypropanoate
1095202-12-2

ethyl 3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxypropanoate

Conditions
ConditionsYield
Stage #1: (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde With zinc In diethyl ether; toluene at 60 - 70℃; for 0.5 - 0.75h;
Stage #2: ethyl bromoacetate In diethyl ether; toluene at 60 - 70℃; for 3h;
46%
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

A

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol
139425-04-0

trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol

B

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol
149968-10-5

(E)-3-<2-(7-chloro-2-quinolinyl)ethenyl>-α-ethenylphenylmethanol

Conditions
ConditionsYield
With vinyl magnesium bromide In tetrahydrofuran at 0 - 5℃; for 1h;A 40%
B n/a
Methyl 3-mercaptopropionate
2935-90-2

Methyl 3-mercaptopropionate

(R)-(-)-α-methoxyphenylthiolacetic acid
115104-46-6

(R)-(-)-α-methoxyphenylthiolacetic acid

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

A

3-[(R)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester
130066-18-1

3-[(R)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester

B

3-[(S)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester
130066-19-2

3-[(S)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methyl-phenol; boron trifluoride diethyl etherate In 1,2-dichloro-ethane for 24h; Ambient temperature; Yield given. Yields of byproduct given;
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

N,N-dimethyl-3-mercaptopropionamide
92065-71-9

N,N-dimethyl-3-mercaptopropionamide

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide
120578-06-5

3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 12 - 14℃; for 24h;
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

-1-<2-<3-<3-<2-(7-chloro-2-quinolinyl)ethenyl>phenyl>-3-hydroxypropyl>phenyl>ethanone
150026-73-6

-1-<2-<3-<3-<2-(7-chloro-2-quinolinyl)ethenyl>phenyl>-3-hydroxypropyl>phenyl>ethanone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
View Scheme
Multi-step reaction with 4 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate
149968-11-6

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

Methanesulfonic acid (R)-3-(2-acetyl-phenyl)-1-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl ester

Methanesulfonic acid (R)-3-(2-acetyl-phenyl)-1-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-propyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
5: Et3N / toluene / 1 h / -5 °C
View Scheme
Multi-step reaction with 5 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
5: Et3N / toluene / 1 h / -5 °C
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

L 699392

L 699392

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
5: Et3N / toluene / 1 h / -5 °C
6: 1) BuLi / 1) THF, hexane, -75 to 10 deg C, 1 h, 2) toluene, 20 deg C, 2 h
View Scheme
Multi-step reaction with 6 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
4: 1) lithium hexamethyldisilazide / 1) THF, 2) toluene, 0 deg C, 1 h
5: Et3N / toluene / 1 h / -5 °C
6: 1) BuLi / 1) THF, hexane, -75 to 10 deg C, 1 h, 2) toluene, 20 deg C, 2 h
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

-2-<3-<3-<2-(7-chloro-2-quinolinyl)ethenyl>phenyl>-3-hydroxypropyl>benzoic acid methyl ester
150026-72-5

-2-<3-<3-<2-(7-chloro-2-quinolinyl)ethenyl>phenyl>-3-hydroxypropyl>benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
View Scheme
Multi-step reaction with 3 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (-)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate
181139-72-0

methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (+)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
View Scheme
Multi-step reaction with 3 steps
1: vinylmagnesium bromide / tetrahydrofuran / 1 h / 0 - 5 °C
2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating
3: 87.1 percent / (+)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

trans-3-<2-(7-chloro-2-quinolinyl)cyclopropyl>benzaldehyde
115104-43-3, 143816-73-3

trans-3-<2-(7-chloro-2-quinolinyl)cyclopropyl>benzaldehyde

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 98 percent / toluene / Heating
2: 1.) n-BuLi / 1.) THF, from -10 deg C to 21 deg C, 2 h, 2.) THF, 0 deg C, overnight
3: 97 percent / tetrahydrofuran; acetic acid; H2O / 2 h / Heating
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

trans-2-<3-<2-(7-chloro-2-quinolinyl)cyclopropyl>phenyl>-1,3-dioxolane
115104-42-2, 143816-72-2

trans-2-<3-<2-(7-chloro-2-quinolinyl)cyclopropyl>phenyl>-1,3-dioxolane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 98 percent / toluene / Heating
2: 1.) n-BuLi / 1.) THF, from -10 deg C to 21 deg C, 2 h, 2.) THF, 0 deg C, overnight
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

trans-5-<3-<2-(7-chloro-2-quinolinyl)cyclopropyl>phenyl>-4,6-dithianonanedioic acid
115104-03-5, 143816-58-4

trans-5-<3-<2-(7-chloro-2-quinolinyl)cyclopropyl>phenyl>-4,6-dithianonanedioic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 98 percent / toluene / Heating
2: 1.) n-BuLi / 1.) THF, from -10 deg C to 21 deg C, 2 h, 2.) THF, 0 deg C, overnight
3: 97 percent / tetrahydrofuran; acetic acid; H2O / 2 h / Heating
4: 71 percent / p-TsOH / toluene / 4.5 h / Heating
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

(E)-5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid
135028-15-8

(E)-5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 49 percent / BF3*Et2O / CHCl3 / 2 h / -8 - 2 °C
2: 88 percent / 1.00 N aq. LiOH / tetrahydrofuran / 4.5 h / -3 - 2 °C
View Scheme
Multi-step reaction with 3 steps
1: imidazole / CH2Cl2 / 24 h / 12 - 14 °C
2: 61 percent / BF3*Et2O / CH2Cl2 / 16 h / -50 °C
3: 88 percent / 1.00 N aq. LiOH / tetrahydrofuran / 4.5 h / -3 - 2 °C
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

(+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate
120443-15-4

(+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: imidazole / CH2Cl2 / 24 h / 12 - 14 °C
2: 61 percent / BF3*Et2O / CH2Cl2 / 16 h / -50 °C
View Scheme
(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide
120578-05-4

3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: imidazole / CH2Cl2 / 24 h / 12 - 14 °C
2: BF3*Et2O / CH2Cl2 / 16 h / -50 °C
View Scheme
(2S,3S)-3-mercapto-2-methylbutanoic acid
863708-50-3

(2S,3S)-3-mercapto-2-methylbutanoic acid

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
120578-03-2

(E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

(2S,3S,2'S,3'S)-3,3'-[({3-[(E)-2-(7-chloroquinolin-2-yl)vinyl]phenyl}methylene)bis(thio)]bis(2-methylbutanoic acid)
863708-45-6

(2S,3S,2'S,3'S)-3,3'-[({3-[(E)-2-(7-chloroquinolin-2-yl)vinyl]phenyl}methylene)bis(thio)]bis(2-methylbutanoic acid)

Conditions
ConditionsYield
With trifluoroacetic acid at 20℃; for 0.25h;

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