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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate supplier in China

Cas:120801-75-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate

Cas:120801-75-4

Min.Order:1

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. As a leading manufacturer and supplier of chemicals in China, Day

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,2-Difluoro-2-(fluorosulfonyl)-acetic acid trimethylsilyl ester

Cas:120801-75-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 120801-75-4 with best quality

Cas:120801-75-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate 120801-75-4

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate CAS:120801-75-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate CAS:120801-75-4

Cas:120801-75-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Kanbei Chemical Co.,LTD

1. Well-equipped, stable and high-quality raw material supply chain, to provide customers with the best quality products. 2.Strict quality inspection process and professional certificate testing to ensure the quality level of the final product. 3.E

hot sale TriMethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate

Cas:120801-75-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate CAS: 120801-75-4 MF: C5H9F3O4SSi MW: 250.27 EINECS: Mol File: 120801-75-4.mol Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate Structure Trimethylsilyl 2-(fluorosulfo

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Trimethylsilyl2-(fluorosulphonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colorless transparent liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceuti

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate cas no. 120801-75-4 98%

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Trimethylsilyl 2(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Other

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate 25g

Cas:120801-75-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

TriMethylsilyl Difluoro(fluorosulfonyl)acetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate

Cas:120801-75-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

Hexamethyldisiloxane
107-46-0

Hexamethyldisiloxane

fluorosulfonyldifluoroacetyl fluoride
677-67-8

fluorosulfonyldifluoroacetyl fluoride

A

trimethylsilyl fluoride
420-56-4

trimethylsilyl fluoride

B

2,2-difluoro-2-(fluorosulfonyl)acetic acid
1717-59-5

2,2-difluoro-2-(fluorosulfonyl)acetic acid

C

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

Conditions
ConditionsYield
Stage #1: Hexamethyldisiloxane; fluorosulfonyldifluoroacetyl fluoride at 0 - 100.6℃; under 4350.44 - 5925.59 Torr; for 18h;
Stage #2: With chloro-trimethyl-silane at 20 - 107.8℃; Product distribution / selectivity; Heating / reflux;
A n/a
B n/a
C 85%
Hexamethyldisiloxane
107-46-0

Hexamethyldisiloxane

fluorosulfonyldifluoroacetyl fluoride
677-67-8

fluorosulfonyldifluoroacetyl fluoride

A

trimethylsilyl fluoride
420-56-4

trimethylsilyl fluoride

B

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

Conditions
ConditionsYield
With chloro-trimethyl-silane at 105℃; under 4200.42 Torr; for 6h;A n/a
B 84%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

2,2-difluoro-2-(fluorosulfonyl)acetic acid
1717-59-5

2,2-difluoro-2-(fluorosulfonyl)acetic acid

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

Conditions
ConditionsYield
at 0 - 20℃; for 26h; Inert atmosphere;83%
at 20℃;78%
at 0℃; Esterification;78%
for 12h; Heating;
at 0 - 65℃; for 19h; Inert atmosphere;
trimethylsilyl iodide
16029-98-4

trimethylsilyl iodide

(fluorosulfonyl)difluoroacetic acid silver salt

(fluorosulfonyl)difluoroacetic acid silver salt

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

Conditions
ConditionsYield
for 24h; -196 deg C upto room temp.;29%
N-(cyclohexylthiocarbonyl)aniline
53300-46-2

N-(cyclohexylthiocarbonyl)aniline

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

S-difluoromethyl N-phenylcyclohexanecarbothioimidate

S-difluoromethyl N-phenylcyclohexanecarbothioimidate

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene at 80℃; for 0.166667h; Temperature; Solvent; Optical yield = 58 %de;100%
4-Methoxyphenylthiocarbamidsaeure-O-isopropylester
22007-40-5

4-Methoxyphenylthiocarbamidsaeure-O-isopropylester

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

S-(difluoromethyl) O-isopropyl N-(p-methoxyphenyl)carbonimidothioate

S-(difluoromethyl) O-isopropyl N-(p-methoxyphenyl)carbonimidothioate

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene at 50℃; for 0.166667h;97%
2-chloro-3-quinoline carboxaldehyde
73568-25-9

2-chloro-3-quinoline carboxaldehyde

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-chloro-3-(2,2-difluorovinyl)quinoline

2-chloro-3-(2,2-difluorovinyl)quinoline

Conditions
ConditionsYield
Stage #1: 2-chloro-3-quinoline carboxaldehyde With sodium fluoride; triphenylphosphine In ethyl acetate at 90℃; for 0.0166667h; Wittig Olefination; Schlenk technique; Inert atmosphere;
Stage #2: trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate In ethyl acetate at 90℃; for 1h; Schlenk technique; Inert atmosphere;
96%
2-bromo-3-[tert-butyl(dimethyl)silyloxy]-1-phenylbuta-1,3-diene

2-bromo-3-[tert-butyl(dimethyl)silyloxy]-1-phenylbuta-1,3-diene

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-(1-bromo-2-phenylethenyl)-1-[tert-butyl(dimethyl)silyloxy]-2,2-difluorocyclopropan

1-(1-bromo-2-phenylethenyl)-1-[tert-butyl(dimethyl)silyloxy]-2,2-difluorocyclopropan

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene at 60℃; for 0.25h;96%
With 1,1,1,3,3,3-hexafluoro-2,2-di(p-tolyl)propane; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In para-xylene at 60℃; for 0.25h; regioselective reaction;
trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

3-(4-methoxyphenyl)-1-phenylprop-2-yn-1-one
20442-66-4

3-(4-methoxyphenyl)-1-phenylprop-2-yn-1-one

[3,3-difluoro-2-(4-methoxy-phenyl)-cycloprop-1-enyl]-phenyl-methanone
882182-82-3

[3,3-difluoro-2-(4-methoxy-phenyl)-cycloprop-1-enyl]-phenyl-methanone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 3h;95%
cinnamyl benzoate
50555-04-9

cinnamyl benzoate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

trans-2,2-difluoro-3-phenylcyclopropylmethyl benzoate

trans-2,2-difluoro-3-phenylcyclopropylmethyl benzoate

Conditions
ConditionsYield
With sodium fluoride In various solvent(s) at 120℃;94%
phenyl o-phenylbenzenedithiocarboxylate

phenyl o-phenylbenzenedithiocarboxylate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-(biphenyl-2-yl)-2,2-difluoro-1-(phenylsulfanyl)ethene

1-(biphenyl-2-yl)-2,2-difluoro-1-(phenylsulfanyl)ethene

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene for 0.5h; Barton-Kellog Olefination; Schlenk technique; Reflux;94%
phenylpropynoic acid methyl ester
4891-38-7

phenylpropynoic acid methyl ester

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

methyl 3,3-difluoro-2-phenylcycloprop-1-ene-1-carboxylate

methyl 3,3-difluoro-2-phenylcycloprop-1-ene-1-carboxylate

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃;94%
2-formylbenzo[b]furan
4265-16-1

2-formylbenzo[b]furan

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-(2,2-difluorovinyl)benzo[b]furan
1449521-09-8

2-(2,2-difluorovinyl)benzo[b]furan

Conditions
ConditionsYield
Stage #1: 2-formylbenzo[b]furan With sodium fluoride; triphenylphosphine In ethyl acetate at 90℃; for 0.0166667h; Wittig Olefination; Schlenk technique; Inert atmosphere;
Stage #2: trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate In ethyl acetate at 90℃; for 1h; Schlenk technique; Inert atmosphere;
93%
methyl N-phenylthiocarbamate
13509-41-6

methyl N-phenylthiocarbamate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

S-(difluoromethyl) O-methyl N-phenylcarbonimidothioate

S-(difluoromethyl) O-methyl N-phenylcarbonimidothioate

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene at 50℃; for 0.166667h;93%
1-pentyl-1-hexenyl acetate
139225-17-5

1-pentyl-1-hexenyl acetate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

5,6-difluoromethylene-6-acetoxyundecane
74667-07-5

5,6-difluoromethylene-6-acetoxyundecane

Conditions
ConditionsYield
With sodium fluoride In various solvent(s) at 120℃;92%
3,6-dimethyl-5-nitropyridin-2-ol
57179-69-8

3,6-dimethyl-5-nitropyridin-2-ol

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-(difluoromethoxy)-3,6-dimethyl-5-nitropyridine
1188407-31-9

2-(difluoromethoxy)-3,6-dimethyl-5-nitropyridine

Conditions
ConditionsYield
Stage #1: 3,6-dimethyl-5-nitropyridin-2-ol With sodium hydride In acetonitrile at 20℃; for 0.5h;
Stage #2: trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate With cesium fluoride In acetonitrile at 23 - 30℃;
92%
With sodium hydride; cesium fluoride In acetonitrile at 23 - 30℃; for 1.66667h; Inert atmosphere;92%
3,6-dimethyl-5-nitropyridin-2-one
57179-69-8

3,6-dimethyl-5-nitropyridin-2-one

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-(difluoromethoxy)-3,6-dimethyl-5-nitropyridine
1188407-31-9

2-(difluoromethoxy)-3,6-dimethyl-5-nitropyridine

Conditions
ConditionsYield
With sodium hydride; cesium fluoride In acetonitrile; mineral oil at 20℃; for 1.16667h;92%
3-[tert-butyl(dimethyl)silyloxy]-2-methyl-1-phenylbuta-1,3-diene

3-[tert-butyl(dimethyl)silyloxy]-2-methyl-1-phenylbuta-1,3-diene

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-[tert-butyl(dimethyl)silyloxy]-2,2-difluoro-1-(1-methyl-2-phenylethenyl)cyclopropane

1-[tert-butyl(dimethyl)silyloxy]-2,2-difluoro-1-(1-methyl-2-phenylethenyl)cyclopropane

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene at 60℃; for 0.25h;92%
With 1,1,1,3,3,3-hexafluoro-2,2-di(p-tolyl)propane; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In para-xylene at 60℃; for 0.25h; regioselective reaction;
phenyl m-chlorobenzenedithiocarboxylate
90982-74-4

phenyl m-chlorobenzenedithiocarboxylate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-m-chlorophenyl-2,2-difluoro-1-(phenylsulfanyl)ethene

1-m-chlorophenyl-2,2-difluoro-1-(phenylsulfanyl)ethene

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In toluene for 0.5h; Barton-Kellog Olefination; Schlenk technique; Reflux;92%
6-methyl-5-nitropyridin-2-ol
28489-45-4

6-methyl-5-nitropyridin-2-ol

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

6-(difluoromethoxy)-2-methyl-3-nitropyridine
1224432-76-1

6-(difluoromethoxy)-2-methyl-3-nitropyridine

Conditions
ConditionsYield
With sodium hydride; cesium fluoride In acetonitrile91%
C17H14O
1429215-66-6

C17H14O

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

phenyl 2,2-difluoro-3-(3,5-dimethylphenyl)cyclopropenyl ketone
1429215-44-0

phenyl 2,2-difluoro-3-(3,5-dimethylphenyl)cyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;91%
m-bromobenzoic aldehyde
3132-99-8

m-bromobenzoic aldehyde

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-bromo-3-(2,2-difluorovinyl)benzene
84750-92-5

1-bromo-3-(2,2-difluorovinyl)benzene

Conditions
ConditionsYield
Stage #1: m-bromobenzoic aldehyde With sodium fluoride; triphenylphosphine In ethyl acetate at 90℃; for 0.0166667h; Wittig Olefination; Schlenk technique; Inert atmosphere;
Stage #2: trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate In ethyl acetate at 90℃; for 1h; Schlenk technique; Inert atmosphere;
91%
1-propenylbenzene
873-66-5

1-propenylbenzene

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

trans-1,1-difluoro-2-methyl-3-phenylcyclopropane

trans-1,1-difluoro-2-methyl-3-phenylcyclopropane

Conditions
ConditionsYield
With sodium fluoride In various solvent(s) at 105℃;90%
trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-(4-(tert-butyl)phenyl)-3-phenylprop-2-yn-1-one
671796-41-1

1-(4-(tert-butyl)phenyl)-3-phenylprop-2-yn-1-one

4-t-butylphenyl 2,2-difluoro-3-phenylcyclopropenyl ketone
882182-78-7

4-t-butylphenyl 2,2-difluoro-3-phenylcyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;90%
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 3h;85%
trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1-phenyl-3-(4-methylphenyl)prop-2-yn-1-one
14939-05-0

1-phenyl-3-(4-methylphenyl)prop-2-yn-1-one

phenyl 2,2-difluoro-3-(4-methylphenyl)cyclopropenyl ketone
882182-83-4

phenyl 2,2-difluoro-3-(4-methylphenyl)cyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 3h;90%
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;87%
1,2,3,4-tetrahydronaphthalen-2-one
530-93-8

1,2,3,4-tetrahydronaphthalen-2-one

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-(difluoromethoxy)naphthalene
712-79-8

2-(difluoromethoxy)naphthalene

Conditions
ConditionsYield
Stage #1: 1,2,3,4-tetrahydronaphthalen-2-one; trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate With sodium carbonate; 1,3-bis(mesityl)imidazolium chloride In toluene at 100℃; for 1h;
Stage #2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone In toluene at 100℃;
90%
vinyl benzoate
583-04-0

vinyl benzoate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

[2,2-difluorocyclopropyl]methylbenzoate

[2,2-difluorocyclopropyl]methylbenzoate

Conditions
ConditionsYield
With sodium fluoride at 105℃;89%
3-butenyl benzoate
18203-32-2

3-butenyl benzoate

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

2-(2,2-difluorocyclopropyl)ethyl benzoate
117388-09-7

2-(2,2-difluorocyclopropyl)ethyl benzoate

Conditions
ConditionsYield
With sodium fluoride at 105℃;89%
With sodium fluoride at 110℃; for 2h; Inert atmosphere;51%
With sodium fluoride In neat (no solvent) at 110℃; for 2h;51%
With sodium fluoride at 110℃; for 12h;50%
With sodium fluoride at 125℃; for 12h; Cycloaddition;
1,3-diphenyl-2-propynone
7338-94-5

1,3-diphenyl-2-propynone

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

phenyl 2,2-difluoro-3-phenylcyclopropenyl ketone
882182-77-6

phenyl 2,2-difluoro-3-phenylcyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 3h;89%
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;85%
1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one
14674-99-8

1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

phenyl 2,2-difluoro-3-(3-methylphenyl)cyclopropenyl ketone
1429215-43-9

phenyl 2,2-difluoro-3-(3-methylphenyl)cyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;89%
6-(2-chloropyrimidin-4-yl)-1-isopropylimidazo[4,5-c]pyridin-4-ol

6-(2-chloropyrimidin-4-yl)-1-isopropylimidazo[4,5-c]pyridin-4-ol

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

C14H12ClF2N5O

C14H12ClF2N5O

Conditions
ConditionsYield
With sodium hydride; cesium fluoride In acetonitrile; mineral oil at 0℃; for 1h;89%
trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

3-(4-bromophenyl)-1-phenylprop-2-yn-1-one
39833-48-2

3-(4-bromophenyl)-1-phenylprop-2-yn-1-one

phenyl 2,2-difluoro-3-(4-bromophenyl)cyclopropenyl ketone
882182-84-5

phenyl 2,2-difluoro-3-(4-bromophenyl)cyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 3h;88%
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;85%
1-<<2-cyclohexylideneethenyl>sulfonyl>-4-methylbenzene
91873-75-5

1-<<2-cyclohexylideneethenyl>sulfonyl>-4-methylbenzene

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

1,1-difluoro-2-[(tolyl-4-sulfonyl)methylidene]spiro[2.5]octane
926033-49-0

1,1-difluoro-2-[(tolyl-4-sulfonyl)methylidene]spiro[2.5]octane

Conditions
ConditionsYield
With sodium fluoride In xylene for 3.16667h; Heating;88%
C23H26O
1429215-67-7

C23H26O

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate
120801-75-4

trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate

phenyl 2,2-difluoro-3-(3,5-di-t-butylphenyl)cyclopropenyl ketone
1429215-45-1

phenyl 2,2-difluoro-3-(3,5-di-t-butylphenyl)cyclopropenyl ketone

Conditions
ConditionsYield
With sodium fluoride In diethylene glycol dimethyl ether at 120℃; for 1h; Inert atmosphere;88%

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