Products

Refine

Country

Business Type

Certificate

Display

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------

High purity 122111-01-7 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product Name 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate CAS No. 122111-01-7 Appearance White powder Assay ≥99% Capacity 200

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Gram

FOB Price: $45.0

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate Cas 122111-01-7 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:97%min Storage:cool dry plac

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99.0% Appearan

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate 122111-01-7 /manufacturer/low price/high quality/in stock

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $15.0 / 16.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-D-erythro-1,4-pentonolactone

Cas:122111-01-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate CAS NO: 122111-01-7 Grade:Medical scientific research and export Molecular formula:C19H14F2O6 Molecular weight:376.3077 Product Quality 12 years of chemical raw materia

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--122111-01-7-- 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China

TIANFUCHEM--122111-01-7-- 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate in stock

Cas:122111-01-7

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Item Specification Test Results Appearance White crystalline powder Conform

China Biggest factory Supply High Quality 2-DEOXY-2,2-DIFLUORO-D-ERYTHRO-PENTOFURANOS-1-ULOSE-3,5-DIBENZOATECAS 122111-01-7

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 122111-01-7 with best quality

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Henan Sinotech Import&Export Corporation

Product Name 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate CAS NO 122111-01-7 Appearance White crystalline powder Assay 99.0-101.0%

2-Deoxy-2,2-difluoropentofuranos-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate 122111-01-7

Cas:122111-01-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates FDA Approved Appearance:white Storage:Sealed in dr

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Qingdao Beluga Import and Export Co., LTD

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate CAS:122111-01-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermed

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate CAS:122111-01-7

Cas:122111-01-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulos-3,5-dibenzoate T6

Cas:122111-01-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Deoxy-2,2-Difluoro-D-Erythro-Pentafuranous-1-Ulose-3,5-Dibenzoate

Cas:122111-01-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Gemcitabine intemediate 122111-01-7

Cas:122111-01-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 122111-01-7 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Deoxy-2,2-Difluoro-D-Erythro-Pentafuranous-1-Ulose-3,5-Dibenzoate

Cas:122111-01-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate

Cas:122111-01-7

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

benzoyl chloride
98-88-4

benzoyl chloride

2-deoxy-2,2-difluoro-1-carbonylribose
95058-77-8

2-deoxy-2,2-difluoro-1-carbonylribose

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1.5h; Reflux;67%
With pyridine; dmap In ethyl acetate at 20℃; for 12h; Reflux;58.3 g
With pyridine In dichloromethane at 0 - 20℃; for 0.666667h;
With pyridine; dmap at 30 - 50℃; for 8h; Inert atmosphere; Large scale;
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C19H16F2O7
866473-33-8

C19H16F2O7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
toluene-4-sulfonic acid In toluene Product distribution / selectivity; Heating / reflux; Dean and Stark apparatus;34%
C5H6F2O4

C5H6F2O4

benzoyl chloride
98-88-4

benzoyl chloride

2-deoxy-2,2-difluoro-1-carbonylribose
95058-77-8

2-deoxy-2,2-difluoro-1-carbonylribose

A

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

B

C19H16F2O7
866473-33-8

C19H16F2O7

C

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
With pyridine; dmap In ethyl acetate at 60 - 65℃; for 6h; Product distribution / selectivity;
C19H16F2O7

C19H16F2O7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
toluene-4-sulfonic acid In toluene Product distribution / selectivity; Heating / reflux; Dean and Stark apparatus;
pyridine
110-86-1

pyridine

benzoyl chloride
98-88-4

benzoyl chloride

2-deoxy-2,2-difluoro-1-carbonylribose
95058-77-8

2-deoxy-2,2-difluoro-1-carbonylribose

A

pyridine hydrochloride
628-13-7

pyridine hydrochloride

B

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
With dmap In ethyl acetate at 60 - 65℃; for 6.25h;
ethyl 2-deoxy-2,2-difluoro-D-erythro,D-threo-pentonate
114420-06-3

ethyl 2-deoxy-2,2-difluoro-D-erythro,D-threo-pentonate

benzoyl chloride
98-88-4

benzoyl chloride

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
Stage #1: ethyl 2-deoxy-2,2-difluoro-D-erythro,D-threo-pentonate; toluene-4-sulfonic acid In water at 75 - 80℃; for 3h;
Stage #2: benzoyl chloride With pyridine; dmap In ethyl acetate at 60 - 65℃; for 3h; Product distribution / selectivity; Dean and Stark apparatus;
2-deoxy-2,2-difluoropentofuranos-1-ulose

2-deoxy-2,2-difluoropentofuranos-1-ulose

benzoyl chloride
98-88-4

benzoyl chloride

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
With pyridine In ethyl acetate at 25 - 60℃; Inert atmosphere;
benzoyl chloride
98-88-4

benzoyl chloride

ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate
928797-50-6

ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
Stage #1: ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate With water; pyridinium trifluroacetate In water; acetonitrile for 3h; Heating / reflux;
Stage #2: benzoyl chloride With pyridine; dmap In ethyl acetate at 0 - 65℃; for 10h; Product distribution / selectivity;
Stage #1: ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate With water; pyridinium p-toluenesulfonate In water; acetonitrile for 12h; Heating / reflux;
Stage #2: benzoyl chloride With pyridine; dmap In ethyl acetate at 0 - 65℃; for 10h; Product distribution / selectivity;
C8H8F2O5

C8H8F2O5

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: acetic acid / chloroform / 2 h / 50 °C
2.1: sodium tetrahydroborate / tetrahydrofuran / 0.5 h
2.2: 2 h / 25 °C
3.1: pyridine; dmap / dichloromethane / 1.5 h / Reflux
View Scheme
ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate
928797-50-6

ethyl (3R,S)-2,2-difluoro-3-hydroxy-(2,2-dimethyldioxolpent-4-yl)propionate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 70 - 80 °C / Large scale
2: pyridine; dmap / 8 h / 30 - 50 °C / Inert atmosphere; Large scale
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

(2R,3R)-2-((benzoyloxy)methyl)-4,4-difluoro-5-hydroxyoxolan-3-yl benzoate
1173824-58-2

(2R,3R)-2-((benzoyloxy)methyl)-4,4-difluoro-5-hydroxyoxolan-3-yl benzoate

Conditions
ConditionsYield
With lithium tri-t-butoxyaluminum hydride In tetrahydrofuran; diethyl ether at 10 - 30℃; for 1h;100%
Stage #1: 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate With sodium bis(2-methoxyethoxy)aluminium dihydride In tetrahydrofuran; toluene at -30℃; for 1h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water; toluene
99.5%
With lithium tri-t-butoxyaluminum hydride In tetrahydrofuran; diethyl ether at -78℃; for 1h; Inert atmosphere;84%
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

Benzoic acid (2R,3R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4,4-difluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Benzoic acid (2R,3R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4,4-difluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
3: 1) Me3SiOTf / 1) 1,1,2-trichloroethane, r.t., 30 min, 2) 113 deg C, 18 h
4: ammonia / methanol
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

1-(2'-deoxy-2',2'-difluoro-3',5'-di-O-benzoyl-D-ribofuranosyl)-4-acetamidopyrimidin-2-one
143157-23-7, 143157-26-0

1-(2'-deoxy-2',2'-difluoro-3',5'-di-O-benzoyl-D-ribofuranosyl)-4-acetamidopyrimidin-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
3: 1) Me3SiOTf / 1) 1,2-dichloroethane, 30 deg C, 1 h, 2) 1,2-dichloroethane, 83 deg C, overnight
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2’-deoxy-2’,2’-difluoro-cytidine
103882-84-4

2’-deoxy-2’,2’-difluoro-cytidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
3: 1) Me3SiOTf / 1) 1,2-dichloroethane, 30 deg C, 1 h, 2) 1,2-dichloroethane, 83 deg C, overnight
4: 1.73 kg / ammonia (gas) / methanol / Ambient temperature
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-D-erythro-pentofuranose
134877-42-2, 134877-43-3, 122111-11-9

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-D-erythro-pentofuranose

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
View Scheme
Multi-step reaction with 2 steps
1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 2 h / -78 - 20 °C / Inert atmosphere
2: triethylamine / dichloromethane / 2 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: lithium tri-(tert-butoxy)aluminum hydride / tetrahydrofuran / 2 h / -78 - 20 °C / Inert atmosphere
2: triethylamine / tetrahydrofuran; dichloromethane / 2 h / 0 - 20 °C
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C23H19F2N3O6
134790-40-2

C23H19F2N3O6

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
3: 1) Me3SiOTf / 1) 1,1,2-trichloroethane, r.t., 30 min, 2) 113 deg C, 18 h
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

(2'-deoxy-2',2'-difluorocytidine)-3',5'-dibenzoate
134790-39-9

(2'-deoxy-2',2'-difluorocytidine)-3',5'-dibenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / LiAl(OBu-t)3H / diethyl ether; tetrahydrofuran / 1 h / 10 - 30 °C
2: 100 percent / triethylamine / CH2Cl2 / 2 h / 23 °C
3: 1) Me3SiOTf / 1) 1,1,2-trichloroethane, r.t., 30 min, 2) 113 deg C, 18 h
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C19H16F2O7

C19H16F2O7

Conditions
ConditionsYield
With hydrogenchloride In water at 45 - 50℃; for 3h;
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

A

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-β-ribofuranose

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-β-ribofuranose

B

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-α-ribofuranose

3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-D-α-ribofuranose

Conditions
ConditionsYield
Stage #1: 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate With sodium bis(2-methoxyethoxy)aluminium dihydride In tetrahydrofuran; toluene at -70 - -50℃; for 1h;
Stage #2: With hydrogenchloride; methanol; water In tetrahydrofuran; toluene for 0.5h;
With lithium tri-t-butoxyaluminum hydride In tetrahydrofuran; diethyl ether at 20℃; for 1.5h; Inert atmosphere; Overall yield = 99.8 %; Overall yield = 10 g;A n/a
B n/a
With sodium tetrahydroborate; zinc(II) chloride; tert-butyl alcohol In tetrahydrofuran; ethyl acetate at 15℃; Overall yield = 100 %;
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C19H15(3)HF2O6

C19H15(3)HF2O6

Conditions
ConditionsYield
Stage #1: 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate With C10H22(3)HB In tetrahydrofuran at 0 - 20℃; for 17.5h; Inert atmosphere; Cooling with ice;
Stage #2: With water In tetrahydrofuran for 0.5h; Inert atmosphere; Reflux;
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C19H15(2)HF2O6

C19H15(2)HF2O6

Conditions
ConditionsYield
Stage #1: 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate With C10H22(2)HB In tetrahydrofuran at 0 - 20℃; for 17.5h; Inert atmosphere; Cooling with ice;
Stage #2: With water In tetrahydrofuran for 0.5h; Inert atmosphere; Reflux;
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-chlorouracil
132786-36-8

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-chlorouracil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)thymine
95058-80-3

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)thymine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C25H25F2IN3O9P
1321580-98-6

C25H25F2IN3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C19H21F2IN3O9P
1321581-00-3

C19H21F2IN3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C29H27F2IN3O9P
1321581-01-4

C29H27F2IN3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C23H23F2IN3O9P
1321581-02-5

C23H23F2IN3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C25H25BrF2N3O9P
1321581-03-6

C25H25BrF2N3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

C25H25ClF2N3O9P
1321581-04-7

C25H25ClF2N3O9P

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
5.1: 1-methyl-1H-imidazole / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-iodouracil
132832-46-3

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-iodouracil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-bromouracil
132786-35-7

1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-bromouracil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
4.1: sodium methylate / methanol / 20 °C / Inert atmosphere
4.2: Amberlite
View Scheme
2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
122111-01-7

2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

A

1-(3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-iodouracil
1321580-93-1

1-(3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-β-D-erythro-pentofuranos-1-yl)-5-iodouracil

B

1-(3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-α-D-erythro-pentofuranos-1-yl)-5-iodouracil

1-(3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-α-D-erythro-pentofuranos-1-yl)-5-iodouracil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran; diethyl ether / 1 h / -78 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate / 1,1-dichloroethane / 10 h / 90 - 100 °C / Inert atmosphere
3.2: 20 °C
View Scheme

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View