As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:129722-12-9
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inquiryOur company Sinoway's advantages: (1) ISO 9001:2008 certificated company & SGS audited supplier (2) 28 years specialized in pharmaceutical /cosmetic raw materials & intermediates (3) China office of Fischer Chemicals AG (Switz
Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------
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inquiryAripiprazole CAS No.:129722-12-9 Name: Aripiprazole Synonyms: 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril Molecular Structure Molecular Formula: C23H27Cl2N3O2 Molecu
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We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
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Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
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inquiryAripiprazole Basic information Outline EU approves aripiprazole for treatment of schizophrenia Metabolize Toxicity Drug Interactions Adverse reactions Application Product Name: Aripiprazole
Cas:129722-12-9
Min.Order:1 Gram
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Cas:129722-12-9
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inquiryAppearance:White powder Storage:Store in cool and dry place, away from sun light. Package:drum Application:Central Nervous System Drug; Antimanic/ Antipsychotic Transportation:By sea or by air Port:Qingdao Port
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Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
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Cas:129722-12-9
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inquiryAripiprazole CAS:129722-12-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat
Cas:129722-12-9
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Cas:129722-12-9
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Overview Quick Details CAS No.: 129722-12-9 Other Names: Aripiprazole MF: C23H27Cl2N3O2, C23H27Cl2N3O2 EINECS No.: 129722-12-9 Place of Origin: Shandong, China (Mainland) Type: Anesthetic Agents, Endocrine System Agents Grade Standard:
Cas:129722-12-9
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inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:129722-12-9
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inquiryAppearance:white powder without visible impurities Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Com
Cas:129722-12-9
Min.Order:100 Metric Ton
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryAripiprazole hydrochloride
aripiprazole
Conditions | Yield |
---|---|
at 100 - 120℃; for 21h; Industrial scale; | 99.3% |
With sodium hydroxide; water In isopropyl alcohol at 15 - 80℃; for 4.5h; pH=>= 12; | |
With sodium hydroxide In methanol; water at 20 - 45℃; |
3,4-dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone
aripiprazole
Conditions | Yield |
---|---|
With potassium carbonate In water for 3h; Reflux; | 98% |
With potassium carbonate In water for 3h; Reflux; | 98% |
With potassium carbonate In water at 90 - 95℃; for 4h; | 92.8% |
7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone methanol solvate
aripiprazole
Conditions | Yield |
---|---|
In isopropyl alcohol Product distribution / selectivity; | 96.8% |
In acetonitrile for 2h; Product distribution / selectivity; Heating / reflux; | 91.4% |
In Isopropyl acetate for 2h; Product distribution / selectivity; Heating / reflux; | 85.7% |
aripiprazole
Conditions | Yield |
---|---|
In isopropyl alcohol Product distribution / selectivity; | 94.6% |
In ethyl acetate Product distribution / selectivity; Heating / reflux; | |
at 90℃; for 6h; Product distribution / selectivity; | |
at 80℃; for 15h; Product distribution / selectivity; |
3,4-dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone
1-(2,3-dichlorophenyl)piperazine
aripiprazole
Conditions | Yield |
---|---|
Stage #1: 7-(4-chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one With sodium iodide In N,N-dimethyl-formamide at 70 - 80℃; for 1h; Stage #2: 1-(2,3-dichlorophenyl)piperazine With potassium carbonate In N,N-dimethyl-formamide at 70 - 80℃; for 4h; | 94% |
With potassium carbonate In N,N-dimethyl-formamide at 100℃; | 57 mg |
carbon monoxide
aripiprazole
Conditions | Yield |
---|---|
With palladium (II) nitrate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In tetrahydrofuran; water at 50℃; under 30003 Torr; for 20h; Pressure; Temperature; Reagent/catalyst; | 94% |
With palladium(II) trifluoroacetate; toluene-4-sulfonic acid In tetrahydrofuran at 80℃; under 26601.8 Torr; for 20h; regioselective reaction; | 1.074 g |
aripiprazole monohydrate
aripiprazole
Conditions | Yield |
---|---|
In isopropyl alcohol Product distribution / selectivity; | 93.6% |
at 60 - 125℃; for 1 - 50h; Conversion of starting material; |
aripiprazole
Conditions | Yield |
---|---|
With ammonia; water In chloroform at 30 - 35℃; for 0.333333h; Product distribution / selectivity; | 93.43% |
Conditions | Yield |
---|---|
With potassium carbonate In water at 99℃; for 5h; Reagent/catalyst; Temperature; | 91.4% |
7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)-butoxy)-3,4-dihydro-2(1H)-carbostyril maleate
aripiprazole
Conditions | Yield |
---|---|
With sodium hydroxide In water; toluene at 65℃; for 0.25h; pH=~ 11; Product distribution / selectivity; | 91% |
With sodium hydroxide In water; toluene at 65 - 80℃; for 0.5h; pH=~ 11; | 91% |
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone
aripiprazole
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile for 2 - 3h; Product distribution / selectivity; Heating / reflux; | 90% |
With sodium carbonate; sodium dodecyl sulfate In acetonitrile for 4h; Product distribution / selectivity; Heating / reflux; | 90% |
With potassium carbonate In acetonitrile at 25 - 85℃; for 8h; | 89% |
3,4-dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone
B
aripiprazole
Conditions | Yield |
---|---|
With potassium carbonate; sodium iodide; tetrabutylammomium bromide In acetonitrile at 20℃; Product distribution / selectivity; Heating / reflux; | A 0.05% B 90% |
1-(2,3-dichlorophenyl)piperazine
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone
aripiprazole
Conditions | Yield |
---|---|
With sodium hydroxide In water; dimethyl sulfoxide; N,N-dimethyl-formamide at 60℃; for 4h; Temperature; | 89.3% |
With triethylamine In acetonitrile at 30 - 81℃; for 4 - 5h; Product distribution / selectivity; | 83.15% |
With triethylamine In acetonitrile for 4h; Reflux; | 53% |
3,4-dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone
aripiprazole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; sodium iodide In pentan-1-ol at 100℃; for 5h; Product distribution / selectivity; Heating / reflux; | 88% |
Stage #1: 7-(4-chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one; 7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone With sodium iodide In acetonitrile for 17h; Heating / reflux; Stage #2: 1-(2,3-dichlorophenyl)-piperazine hydrochloride With triethylamine In acetonitrile for 23h; Product distribution / selectivity; Heating / reflux; | 83% |
3,4-dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone
aripiprazole
Conditions | Yield |
---|---|
With potassium carbonate In water at 85 - 90℃; for 3.16h; Temperature; Solvent; Large scale; | 88% |
With potassium carbonate; sodium iodide In acetonitrile Reflux; Large scale; | 3.6 kg |
aripiprazole
Conditions | Yield |
---|---|
With sodium hydroxide In water Product distribution / selectivity; | 85% |
With sodium carbonate In dichloromethane; water pH=9.0; |
aripiprazole
Conditions | Yield |
---|---|
With sodium hydroxide In water; toluene at 65℃; for 0.25h; pH=~ 11; Product distribution / selectivity; | 84% |
aripiprazole
Conditions | Yield |
---|---|
With triethylamine; sodium iodide In acetonitrile at 0 - 82℃; for 4h; Heating / reflux; | 83.3% |
aripiprazole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; (cyanomethyl) tri-n-butylphosphonium iodide In toluene at 30 - 40℃; for 4h; Reagent/catalyst; Solvent; Inert atmosphere; | 83% |
aripiprazole
Conditions | Yield |
---|---|
With triethylamine In cyclohexane; N,N-dimethyl-formamide at 25 - 35℃; for 0.833333h; Product distribution / selectivity; | 81.3% |
aripiprazole
Conditions | Yield |
---|---|
With triethylamine In dichloromethane; water at 25 - 35℃; for 0.833333h; Product distribution / selectivity; | 78.3% |
With triethylamine In N,N-dimethyl-formamide; acetone at 25 - 35℃; for 0.833333h; Product distribution / selectivity; | 78.3% |
With triethylamine In water; ethyl acetate at 70 - 75℃; for 0.833333h; Product distribution / selectivity; | 68.8% |
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone
B
aripiprazole
Conditions | Yield |
---|---|
Product distribution / selectivity; | A 0.5% B 78% |
aripiprazole
Conditions | Yield |
---|---|
With triethylamine In cyclohexane; N,N-dimethyl-formamide at 25 - 35℃; for 0.833333h; Product distribution / selectivity; | 77.2% |
aripiprazole
Conditions | Yield |
---|---|
With sodium hydroxide In water; toluene at 65℃; for 0.25h; pH=~ 11; Product distribution / selectivity; | 76% |
7-(4-chlorobutoxy)-3,4-dihydrocarbostyril
aripiprazole
Conditions | Yield |
---|---|
With potassium carbonate In water for 3h; | 74.2% |
aripiprazole-benzenesulfonic acid
aripiprazole
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide; acetone at 25 - 35℃; for 0.833333h; Product distribution / selectivity; | 68.4% |
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