CAS No.130931-85-0,(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochloride Suppliers

Qingdao Beluga Import and Export Co., LTD

(1R,4S)-4-AMINO-CYCLOPENT-2-ENECARBOXYLIC ACID HYDROCHLORIDE CAS:130931-85-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates,

(1R,4S)-4-AMINO-CYCLOPENT-2-ENECARBOXYLIC ACID HYDROCHLORIDE CAS:130931-85-0

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Shandong Hanjiang Chemical Co., Ltd.

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(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochloride

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochloride

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Henan Tianfu Chemical Co., Ltd.

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

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Hangzhou Fandachem Co.,Ltd

(1R,4S)-4-aminocyclopent-2-enecarboxylic acid hydrochlorideAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

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Henan Kanbei Chemical Co.,LTD

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Shanghai Chinqesen Biotechnology Co., Ltd.

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ZHEJIANG JIUZHOU CHEM CO.,LTD

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Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

4-amino-1-cyclopent-2-enecarboxylic acid hydrochloride

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ENAO Chemical Co, Limited

For quick quotation, please send us the inquiry include CAS#, Structure, Chemical Name, quantity, purity, as well as any additional specifications you require, we will try to get back to you within 24 hours. Our Services Besides manufacturing,

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the (1R,4S)-4-AMINO-CYCLOPENT-2-ENECARBOXYLIC ACID HYDROCHLORIDE, CAS:130931-85-0 with th

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Nanjing Raymon Biotech Co., Ltd.

(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochlorideAppearance:Off white to slight yellow solid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportat

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Hebei Ruishun Trade Co.,Ltd

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Beyond Pharmaceutical Co., Ltd

Used in medicine Application:Used in medicine

(1R,4S)-4-aminocyclopent-2-enecarboxylic acid hydrochloride

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Chemical Co.Ltd

(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochlorideAppearance:Off white to slight yellow solid Storage:Stored in shaded, cool and dry places Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:Handle with cares to avo

(1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid hydrochloride

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Synthetic route

: 130931-83-8
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water for 2h; Reflux;	90%

: 200002-41-1
(-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate]

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water for 2h; Reflux;	82%

: 151907-80-1
(1R,4S)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylic acid

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In 1,4-dioxane at 20℃; for 2h;

: racemic N-hydroxymethyl vince lactam

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 0.5 h / 60 °C / Enzymatic reaction 2: hydrogenchloride; water / 5 h / Reflux View Scheme
Multi-step reaction with 2 steps 1: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 2 h / 60 °C / Enzymatic reaction 2: hydrogenchloride; water / 5 h / Reflux View Scheme

: 157810-20-3
(1S,4R)-N-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; water for 5h; Reflux;

: 49805-30-3
racemic 2-azabicyclo[2.2.1]hept-5-en-3-one

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: Sonication 2: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 0.5 h / 60 °C / Enzymatic reaction 3: hydrogenchloride; water / 5 h / Reflux View Scheme
Multi-step reaction with 3 steps 1: Sonication 2: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 2 h / 60 °C / Enzymatic reaction 3: hydrogenchloride; water / 5 h / Reflux View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: 569685-43-4
4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzaldehyde

: 1008769-14-9
(1R,4S)-4-(4-((4-phenyl-5-(trifluoromethyl)thiophene-2-yl)methoxy)benzylamino)cyclopentan-2-encarboxylic acid

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride In dichloromethane at 20℃; for 6h;

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-methyl (1R,2S,4R,5S)-2-(tert-butoxycarbonylamino)bicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: 251326-99-5
(1R,4S)-N-tert-butoxycarbonyl-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: acetyl chloride / 16 h / 80 °C 2: triethylamine / dichloromethane / 3 h / 20 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (1S,4S)-N-tert-butoxycarbonyl-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: acetyl chloride / 16 h / 80 °C 2: triethylamine / dichloromethane / 3 h / 20 °C 3: sodium methylate / methanol / 1 h / -10 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: methyl (1R,2S,4S,5S)-2-(tert-butoxycarbonylamino)bicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-(1R,2S,4R,5S)-2-[[5-fluoro-2-(5-fluoro-1H-pyrazolo[3,4-b]pyridin-3yl)pyrimidin-4-yl]amino]bicyclo[3.1.0]hexane-4-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 6.2: 1 h / 130 °C / Microwave irradiation 7.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C 8.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C View Scheme

Yield

Multi-step reaction with 8 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
3.2: 16 h / 0 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
6.2: 1 h / 130 °C / Microwave irradiation
7.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C
8.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C
View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (1R,2S,4S,5S)-2-[[5-fluoro-2-(5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[3.1.0]hexane-4-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 9 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C 5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 7.2: 1 h / 130 °C / Microwave irradiation 8.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C 9.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C View Scheme

Yield

Multi-step reaction with 9 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: sodium methylate / methanol / 1 h / -10 °C
4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
4.2: 2 h / 0 - 20 °C
5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
7.2: 1 h / 130 °C / Microwave irradiation
8.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C
9.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C
View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-methyl (1R,2S,4R,5S)-2-aminobicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-methyl (1R,2S,4R,5S)-2-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-methyl (1R,2S,4R,5S)-2-[[5-fluoro-2-(5-fluoro-1-tetrahydropyran-2-yl-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 6.2: 1 h / 130 °C / Microwave irradiation View Scheme

Yield

Multi-step reaction with 6 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
3.2: 16 h / 0 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
6.2: 1 h / 130 °C / Microwave irradiation
View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-(1R,2S,4R,5S)-2-({5-fluoro-2-[5-fluoro-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-yl}amino)bicyclo[3.1.0]hexane-4-carboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 3.2: 16 h / 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 6.2: 1 h / 130 °C / Microwave irradiation 7.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C View Scheme

Yield

Multi-step reaction with 7 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
3.2: 16 h / 0 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
5.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
6.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
6.2: 1 h / 130 °C / Microwave irradiation
7.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C
View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: methyl (1R,2S,4S,5S)-2-aminobicyclo[3.1.0]hexane-4-carboxylate

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C 5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C View Scheme

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C 5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C View Scheme

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C 5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 7.2: 1 h / 130 °C / Microwave irradiation View Scheme

Yield

Multi-step reaction with 7 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: sodium methylate / methanol / 1 h / -10 °C
4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
4.2: 2 h / 0 - 20 °C
5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
7.2: 1 h / 130 °C / Microwave irradiation
View Scheme

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1.1: acetyl chloride / 16 h / 80 °C 2.1: triethylamine / dichloromethane / 3 h / 20 °C 3.1: sodium methylate / methanol / 1 h / -10 °C 4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C 4.2: 2 h / 0 - 20 °C 5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C 7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation 7.2: 1 h / 130 °C / Microwave irradiation 8.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C View Scheme

Yield

Multi-step reaction with 8 steps
1.1: acetyl chloride / 16 h / 80 °C
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: sodium methylate / methanol / 1 h / -10 °C
4.1: diethylzinc / dichloromethane; hexane / 0.25 h / 0 °C
4.2: 2 h / 0 - 20 °C
5.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
6.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 16 h / 60 °C
7.1: bis(pinacol)diborane; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.5 h / 100 °C / Microwave irradiation
7.2: 1 h / 130 °C / Microwave irradiation
8.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 2 h / 20 °C
View Scheme

methanol: methanol

: 130931-85-0
(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

: (+)-methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride

Conditions

Conditions	Yield
With acetyl chloride at 80℃; for 16h;

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