Products

Refine

Country

Business Type

Certificate

Display

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE

Cas:130931-83-8

Min.Order:1

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, inter

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

(1S,4R)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(+)-2-Azabicyclo-[2.2.1]-hept-5-en-3-one

Cas:130931-83-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 130931-83-8 with fast shipping

Cas:130931-83-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

130931-83-8 CAS NO.130931-83-8

Cas:130931-83-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co. Ltd. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. We are manufacture for the materials, and other sarms, steriods. We also produce. We expo

high quality (1S,4R)-(+)-2-azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Kilogram

FOB Price: $280.0

Type:Manufacturers

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

(1S)-(+)-2-Azabicyclo[2.2.1]Hept-5-En-3-One

Cas:130931-83-8

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(1R,4S)-3-Azabicyclo[2.2.1]hept-5-en-2-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(1R,4S)-3-Azabicyclo[2.2.1]hept-5-en-2-one cas no. 130931-83-8 98%

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(1S,4R)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(1S,4R)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(1R,4S)-3-Azabicyclo[2.2.1]hept-5-en-2-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

(1R,4S)-3-Azabicyclo[2.2.1]hept-5-en-2-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one CAS No.130931-83-8

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

130931-83-8

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(1S,4R)-2-Azabicyclo[2.2.1]hept-5-en-3-one cas 130931-83-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(1S,4R)-2-Azabicyclo[2.2.1]hept-5-en-3-one cas 130931-83-8

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:250mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

(1S,4R)-2-Aza-bicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

Cas:130931-83-8

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

(1S,4R)-N-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one
157810-20-3

(1S,4R)-N-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With ammonium hydroxide In methanol at 20℃; for 4h;95%
With ammonium hydroxide In methanol for 12h; Ambient temperature;45%
With methanol; ammonium hydroxide for 13h; Ambient temperature;38%
racemic 2-azabicyclo[2.2.1]hept-5-en-3-one
49805-30-3

racemic 2-azabicyclo[2.2.1]hept-5-en-3-one

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With resin-supported recombinant Candida antarctica lipase B; water In tert-butyl methyl ether at 60℃; for 102h; enantioselective reaction;48%
With citrophilla (ATCC No.21285) In phosphate buffer for 24h; pH=7.5;31.8%
With lipase B Candida antarctica recombined fromAspergillus oryzae In aq. phosphate buffer for 168h; Reagent/catalyst; Enzymatic reaction;n/a
Multi-step reaction with 3 steps
1: Sonication
2: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 0.5 h / 60 °C / Enzymatic reaction
3: ammonium hydroxide / methanol / 4 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: Sonication
2: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 2 h / 60 °C / Enzymatic reaction
3: ammonium hydroxide / methanol / 4 h / 20 °C
View Scheme
racemic 2-azabicyclo[2.2.1]hept-5-en-3-one
49805-30-3

racemic 2-azabicyclo[2.2.1]hept-5-en-3-one

A

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

B

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid

Conditions
ConditionsYield
With lipase B from Candida antarctica In water; isopropyl alcohol at 60℃; for 4h; Enzymatic reaction; stereospecific reaction;A 46%
B 48%
With water In tert-butyl methyl ether Enzymatic reaction; optical yield given as %ee;
(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one
169104-33-0

(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In water; acetonitrile at 0℃; for 2.5h;26%
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,6S)-6-Chlorocarbonyl-cyclohex-3-enecarboxylic acid isopropyl ester

(1R,6S)-6-Chlorocarbonyl-cyclohex-3-enecarboxylic acid isopropyl ester

A

(3aS,7aR)-3a,4,7,7a-tetrahydroisobenzofuran-1(3H)-one
88586-06-5

(3aS,7aR)-3a,4,7,7a-tetrahydroisobenzofuran-1(3H)-one

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With sodium tetrahydroborate; camphor-10-sulfonic acid 1.) THF, EtOH, -40 degC, 3 h; 2.) toluene, reflux, 5 h; Yield given. Multistep reaction;
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

A

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
79200-56-9

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With brucine In methanol at 20℃; for 6h;
With Methylobacterium sp. Y1-6 at 30℃; for 24h; Overall yield = 19 %Chromat.;A n/a
B n/a
With malonamidase E2 (MAE2) In aq. phosphate buffer at 30℃; for 24h; pH=7.5; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
With Cu-(R)-2,2'-dihydroxy-1,1'-binaphthalene-6,6'-dicarboxylic acid organic framework silica composite In ethanol; hexane Resolution of racemate;
2-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one
157732-10-0

2-hydroxymethyl-2-azabicyclo<2.2.1>hept-5-en-3-one

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 45 percent / aq. NH3 / methanol / 12 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
2: 38 percent / Nh4OH, MeOH / 13 h / Ambient temperature
View Scheme
(1S,6R)-6-(isopropoxycarbonyl)cyclohex-3-enecarboxylic acid
181136-52-7

(1S,6R)-6-(isopropoxycarbonyl)cyclohex-3-enecarboxylic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CH2Cl2 / 3 h / Ambient temperature
2: 1.) NaBH4; 2.) camphorsulfonic acid / 1.) THF, EtOH, -40 degC, 3 h; 2.) toluene, reflux, 5 h
View Scheme
cis-1,2,3,6-tetrahydrophthalic anhydride
935-79-5

cis-1,2,3,6-tetrahydrophthalic anhydride

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) TADDOL / 1.) Et2O, r.t., 3 h; 2.) THF, -20 degC, 10 d
2: CH2Cl2 / 3 h / Ambient temperature
3: 1.) NaBH4; 2.) camphorsulfonic acid / 1.) THF, EtOH, -40 degC, 3 h; 2.) toluene, reflux, 5 h
View Scheme
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

A

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

B

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid

Conditions
ConditionsYield
With water In tert-butyl methyl ether Enzymatic reaction; optical yield given as %ee; enantioselective reaction;
With Bradyrhizobium japonicum USDA 6 (−)-γ-lactamase In aq. buffer at 50℃; pH=6; Kinetics; Temperature; pH-value; Concentration; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
With cyclic imide hydrolase(CIH) In aq. phosphate buffer at 30℃; for 24h; pH=7.5; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

A

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
79200-56-9

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

C

(1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid
134003-04-6

(1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid

Conditions
ConditionsYield
With Nocardia farcinica-polyamidase (NfpolyA) In aq. phosphate buffer at 30℃; for 24h; pH=7.5; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

A

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

B

(1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid
134003-04-6

(1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid

C

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid

Conditions
ConditionsYield
With non-heme chloroperoxidase (CPO-T) In aq. phosphate buffer at 30℃; for 24h; pH=7.5; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a
racemic N-hydroxymethyl vince lactam

racemic N-hydroxymethyl vince lactam

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 0.5 h / 60 °C / Enzymatic reaction
2: ammonium hydroxide / methanol / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: water; lipase B from Candida antarctica; benzylamine / isopropyl alcohol / 2 h / 60 °C / Enzymatic reaction
2: ammonium hydroxide / methanol / 4 h / 20 °C
View Scheme
racemic 2-azabicyclo[2.2.1]hept-5-en-3-one
49805-30-3

racemic 2-azabicyclo[2.2.1]hept-5-en-3-one

A

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
79200-56-9

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

C

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid

Conditions
ConditionsYield
With water; lipase B from Candida antarctica In isopropyl alcohol at 60℃; for 0.5h; Enzymatic reaction;A n/a
B n/a
C n/a
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

C6H9NO2

C6H9NO2

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With chloroperoxidase In aq. phosphate buffer at 30℃; for 0.5h; pH=7; Kinetics; Reagent/catalyst; Temperature; Solvent; pH-value; Resolution of racemate; Green chemistry; Enzymatic reaction; enantioselective reaction;A n/a
B 2.1 g
2-azabicyclo[2.2.1.]hept-5-en-3-one
49805-30-3

2-azabicyclo[2.2.1.]hept-5-en-3-one

C6H9NO2

C6H9NO2

B

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
79200-56-9

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one

C

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With CfGL2 In aq. phosphate buffer at 30℃; for 9h; pH=7; Resolution of racemate; Green chemistry; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
C n/a
(1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate

(1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine; methanol; lithium hydroxide; water / -20 °C / pH 6 - 7
2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 18 h / 45 °C
View Scheme
(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

(-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 45℃; for 18h;n/a
racemic 2-azabicyclo[2.2.1]hept-5-en-3-one
49805-30-3

racemic 2-azabicyclo[2.2.1]hept-5-en-3-one

A

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one
79200-56-9

(-)-2-azabicyclo[2.2.1]hept-5-en-3-one

B

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

cis-4-amino-cyclopent-2-ene-1-carboxylic acid
102579-71-5, 102579-72-6, 102679-78-7, 134003-04-6, 134234-04-1

cis-4-amino-cyclopent-2-ene-1-carboxylic acid

Conditions
ConditionsYield
With (+) γ-lactamase immobilized on epoxy graphene oxide carrier In aq. phosphate buffer at 80℃; pH=8; Kinetics; Reagent/catalyst; Enzymatic reaction;
3-((2S,5R)-2-Isopropyl-5-methyl-cyclohexanesulfonyl)-2-aza-bicyclo[2.2.1]hepta-2,5-diene

3-((2S,5R)-2-Isopropyl-5-methyl-cyclohexanesulfonyl)-2-aza-bicyclo[2.2.1]hepta-2,5-diene

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

Conditions
ConditionsYield
With sodium hydroxide In water; acetic acid
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(-)-2-Azabicyclo<2.2.1>heptan-3-one
134003-02-4

(-)-2-Azabicyclo<2.2.1>heptan-3-one

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;100%
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;100%
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 2h;98%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate]
200002-41-1

(-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate]

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran100%
With pyridine; dmap at 20℃; for 3h;100%
With dmap; triethylamine In tetrahydrofuran at 0 - 20℃;93%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,3R)-3-aminocyclopentanecarboxylic acid
71830-07-4

(1S,3R)-3-aminocyclopentanecarboxylic acid

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;100%
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;100%
Multi-step reaction with 3 steps
1: 79 percent / bromine / CH2Cl2 / 0.25 h / Ambient temperature
2: 87 percent / tributyltin hydride, azobisisobutyronitrile / toluene / 5 h / Heating
3: 97 percent / aq. HCl / Heating
View Scheme
methanol
67-56-1

methanol

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,4S)-methyl 4-aminocyclopent-2-enecarboxylate hydrochloride salt

(1R,4S)-methyl 4-aminocyclopent-2-enecarboxylate hydrochloride salt

Conditions
ConditionsYield
With thionyl chloride at 0 - 20℃; for 12h;100%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(+)-methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride

(+)-methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride

Conditions
ConditionsYield
With thionyl chloride; 2-azabicyclo[2.2.1.]hept-5-en-3-one In methanol at 20℃; for 2h;100%
With thionyl chloride In methanol at 20℃; for 2h;5.36 g
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

2-Azabicyclo[2.2.1]heptan-3-one
24647-29-8

2-Azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;100%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(+/-)-cis-4-amino-2-cyclopentene-1-carboxylic acid methanesulfonate

(+/-)-cis-4-amino-2-cyclopentene-1-carboxylic acid methanesulfonate

Conditions
ConditionsYield
98.2%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,4R,6S,7R)-6,7-dibromo-2-azabicyclo[2.2.1]heptan-3-one
262280-21-7

(1R,4R,6S,7R)-6,7-dibromo-2-azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With bromine In dichloromethane at 0℃; for 2h; Bromination;98%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

C7H13NO2
625108-11-4

C7H13NO2

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;96%
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 24h;
Stage #2: With hydrogenchloride In methanol; water at 20℃; for 72h;
96%
Multi-step reaction with 2 steps
1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 24 h / 20 °C
2: hydrogenchloride; water / 72 h / 20 °C
View Scheme
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,3R)-3-amino-cyclopentanecarboxylic acid methyl ester hydrochloride

(1S,3R)-3-amino-cyclopentanecarboxylic acid methyl ester hydrochloride

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With hydrogen; palladium 10% on activated carbon In ethyl acetate for 24h;
Stage #2: With hydrogenchloride In methanol; water at 20℃; for 72h;
96%
Multi-step reaction with 2 steps
1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 24 h / 20 °C
2: hydrogenchloride / water / 72 h / 20 °C
View Scheme
methanol
67-56-1

methanol

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(+)-methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride

(+)-methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 2 - 8℃; for 1.5h; Inert atmosphere; Industrial scale;95%
With thionyl chloride at 0℃; for 2h;
With thionyl chloride at 0 - 13℃; for 4.25h;
With hydrogenchloride In water for 16h; Sealed tube; Heating;
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

(1S,4R)-2-But-2-ynyl-2-aza-bicyclo[2.2.1]hept-5-en-3-one
666256-77-5

(1S,4R)-2-But-2-ynyl-2-aza-bicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate92%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

allyl bromide
106-95-6

allyl bromide

(1S)-2-(allyl)-2-azabicyclo[2.2.1]hept-5-en-3-one
406218-20-0

(1S)-2-(allyl)-2-azabicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 3h; Heating;90%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride
130931-85-0

(+)-(1R,4S)-4-aminocyclopent-2-ene-1-carboxylic acid hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 2h; Reflux;90%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

methyl iodide
74-88-4

methyl iodide

(1S,4R)-2-methyl-2-azabicyclo[2.2.1]hept-5-en-3-one

(1S,4R)-2-methyl-2-azabicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
With caesium carbonate In butanone at 35℃; Inert atmosphere;90%
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 20℃; for 16h;
75%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one
169104-33-0

(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: p-methoxybenzyl chloride With tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;
90%
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.0833333h;
Stage #2: p-methoxybenzyl chloride With tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 4.5h;
21.4 g
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one

(1S,4R)-2-[(4-methoxyphenyl)methyl]-2-azabicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: p-methoxybenzyl chloride With tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide; mineral oil at 0℃;
90%
ethanol
64-17-5

ethanol

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,4S)-ethyl 4-aminocyclopent-2-enecarboxylate hydrochloride
229613-87-0

(1R,4S)-ethyl 4-aminocyclopent-2-enecarboxylate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 0℃; for 1h;89%
With hydrogenchloride In water at 0℃; for 1h;73%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

4-methoxycarbonylphenylboronic acid
99768-12-4

4-methoxycarbonylphenylboronic acid

methyl 4-((1S,4S,6R)-3-oxo-2-azabicyclo[2.2.1]heptan-6-yl)benzoate

methyl 4-((1S,4S,6R)-3-oxo-2-azabicyclo[2.2.1]heptan-6-yl)benzoate

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene In tetrahydrofuran; water at 23℃; for 64h; Inert atmosphere; regioselective reaction;89%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(+)-cis-4-amino-2-cyclopentene-1-methanol

(+)-cis-4-amino-2-cyclopentene-1-methanol

Conditions
ConditionsYield
88.8%
tert-butyldicarbonate
34619-03-9

tert-butyldicarbonate

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene
168960-18-7

(1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With methanesulfonic acid In tetrahydrofuran; water at 34 - 44℃; for 2.75h; Heating / reflux;
Stage #2: With lithium aluminium tetrahydride In tetrahydrofuran for 18.5h; Heating / reflux;
Stage #3: tert-butyldicarbonate With sodium fluoride more than 3 stages;
88%
2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,4S,6R)-6-(o-tolyl)-2-azabicyclo[2.2.1]heptan-3-one

(1S,4S,6R)-6-(o-tolyl)-2-azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene In tetrahydrofuran; water at 23℃; for 64h; Inert atmosphere; regioselective reaction;87%
benzyl bromide
100-39-0

benzyl bromide

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,4R)-2-benzyl-2-azabicyclo[2.2.1 ]hept-5-en-3-one

(1S,4R)-2-benzyl-2-azabicyclo[2.2.1 ]hept-5-en-3-one

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: benzyl bromide In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil at 20℃; Inert atmosphere;
87%
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: benzyl bromide at 20℃; for 72h;
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate
204913-00-8

(1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With hydrogen; palladium 10% on activated carbon In methanol under 2585.81 Torr; for 1h;
Stage #2: di-tert-butyl dicarbonate With dmap In dichloromethane at 20℃;
86%
Stage #1: (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one With palladium 10% on activated carbon; hydrogen In methanol at 40℃; under 7500.75 Torr;
Stage #2: di-tert-butyl dicarbonate With dmap In acetonitrile at 20℃; for 2h;
1.94 g
3-methoxyphenylboronic acid
10365-98-7

3-methoxyphenylboronic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,4S,6R)-6-(3-methoxyphenyl)-2-azabicyclo[2.2.1]heptan-3-one

(1S,4S,6R)-6-(3-methoxyphenyl)-2-azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene In tetrahydrofuran; water at 23℃; for 64h; Inert atmosphere; regioselective reaction;86%
1-bromo-4-butene
5162-44-7

1-bromo-4-butene

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S)-2-(but-3-enyl)-2-azabicyclo[2.2.1]hept-5-en-3-one
406218-21-1

(1S)-2-(but-3-enyl)-2-azabicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 3h; Heating;85%
(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

propargyl bromide
106-96-7

propargyl bromide

(1S,4R)-2-Prop-2-ynyl-2-aza-bicyclo[2.2.1]hept-5-en-3-one
666256-76-4

(1S,4R)-2-Prop-2-ynyl-2-aza-bicyclo[2.2.1]hept-5-en-3-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate85%
4-trifluoromethylphenylboronic acid
128796-39-4

4-trifluoromethylphenylboronic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,4S,6R)-6-(4-(trifluoromethyl)phenyl)-2-azabicyclo[2.2.1]heptan-3-one

(1S,4S,6R)-6-(4-(trifluoromethyl)phenyl)-2-azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene In tetrahydrofuran; water at 23℃; for 17h; Inert atmosphere; regioselective reaction;83%
4-Bromophenylboronic acid
5467-74-3

4-Bromophenylboronic acid

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one
130931-83-8

(1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one

(1S,4S,6R)-6-(4-bromophenyl)-2-azabicyclo[2.2.1]heptan-3-one

(1S,4S,6R)-6-(4-bromophenyl)-2-azabicyclo[2.2.1]heptan-3-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene In tetrahydrofuran; water at 23℃; for 64h; Inert atmosphere; regioselective reaction;83%

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View