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Suzhou Lipin chemical Co., Ltd.

high quality ,iso , cgmp . accept the supplier audit . in stock now ,capacity is flexible support the documents Appearance:Colorless to Light yellow liquid Storage: protect from light seal room temperature Package:DRUM Application:Key interm

3355-28-0 1-BROMO-2-BUTYNE

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1-Bromo-2-Butyne supplier in China

Cas:3355-28-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hangzhou Think Chemical Co. Ltd

Linagliptin[CAS:668270-12-0] 1-Bromo-2-Butyne[CAS:3355-28-0] HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the ma

High purity 1-Bromo-2-butyne for Linagliptin

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White

1-BROMO-2-BUTYNE

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-Bromo-2-Butyne

Cas:3355-28-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 3355-28-0 1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99

A1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

CHemwill -- 1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1054.html Product Name 1-Bromo-2-butyne CAS No. 3355-28-0

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Gram

FOB Price: $45.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1-BROMO-2-BUTYNE Basic information Product Name: 1-BROMO-2-BUTYNE Synonyms: 1-BROMO-2-BUTYNE;2-BUTYNYL BROMIDE;1-BROMO-2-BUTYNE 98%;1-Bromo-2-butyne,98%;1-Bromobut-

TIANFU-CHEM 1-BROMO-2-BUTYNE 3355-28-0

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

1-Bromo-2-Butyne CAS 3355-28-0

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

HPLC 98% CAS 3355-28-0 with high-quality service

Cas:3355-28-0

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 1-BROMO-2-BUTYNE Synonyms: 1-BROMO-2-BUTYNE;2-BUTYNYL BROMIDE;1-BROMO-2-BUTYNE 98%;1-Bromo-2-butyne,98%;1-Bromobut-2-yne;But-2-yn-1-yl bromide;1-broMo -2-Ding Que;1-BroMo-2-butyne, 96.0%(GC)

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

1-BROMO-2-BUTYNE CAS NO 3355-28-0

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Bromo-2-butyne 3355-28-0

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

1-Bromo-2-butyne/ LIDE PHARMA- Factory supply / Best price

Cas:3355-28-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Wuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides

Linagliptin Intermediate CAS 3355-28-0

Cas:3355-28-0

Min.Order:100 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1-BROMO-2-BUTYNE Synonyms: 1-BROMO-2-BUTYNE;2-BUTYNYL BROMIDE;1-Bromobut-2-yne 95%;1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%;1-BROMO-2-BUTYNE 98%;1-Bromo-2-butyne,98%;But-2-yn-1-yl bromid

1-BROMO-2-BUTYNE

Cas:3355-28-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

1-BROMO-2-BUTYNE

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $200.0 / 240.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

1-BROMO-2-BUTYNE CAS:3355-28-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

1-BROMO-2-BUTYNE CAS:3355-28-0

Cas:3355-28-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3355-28-0

Cas:3355-28-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

1-Bromo-2-butyne cas:3355-28-0

Cas:3355-28-0

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

1-Bromo-2-butyne

Cas:3355-28-0

Min.Order:1 Kilogram

FOB Price: $70.0 / 90.0

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance & Physical State: Clear pale yellow-greenish liquid Density: 1.519 Boiling Point: 40-41ºC (20 mmHg) Flash Point: 36ºC Refra

1-bromo-2-butyne

Cas:3355-28-0

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

1-Bromo-2-Butyne

Cas:3355-28-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methyl propargyl alcohol
764-01-2

methyl propargyl alcohol

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
With bromine; triphenylphosphine In dichloromethane at 0℃; for 1h;100%
With phosphorus tribromide89%
With bromine; triphenylphosphine In dichloromethane at 0℃; for 1h;89%
2-But-2-ynyl-1,3-diisopropyl-isourea
113984-38-6

2-But-2-ynyl-1,3-diisopropyl-isourea

A

1,3-diisopropylurea
4128-37-4

1,3-diisopropylurea

B

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; tetrabutylammomium bromide In dichloromethane at 40℃; for 15h;A n/a
B 58%
4-methoxy-but-2-yne
2768-41-4

4-methoxy-but-2-yne

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
With Acetyl bromide; zinc dibromide at 60 - 65℃;
tetra-N-methyl-phosphorodiamidic acid but-2-ynyl ester
53799-88-5

tetra-N-methyl-phosphorodiamidic acid but-2-ynyl ester

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
With phosphorus tribromide In diethyl ether for 4h; Heating;
tetra-N-methyl-phosphorodiamidic acid prop-2-ynyl ester
53799-85-2

tetra-N-methyl-phosphorodiamidic acid prop-2-ynyl ester

methyl iodide
74-88-4

methyl iodide

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
(i) NaH, (ii) PBr3; Multistep reaction;
methyl propargyl alcohol
764-01-2

methyl propargyl alcohol

phosphorus tribromide
7789-60-8

phosphorus tribromide

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Conditions
ConditionsYield
With pyridine In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; pentane11.0 g (58%)
With pyridine In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; pentane11.0 g (58%)
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

8,9-anhydroerythromycin A 6,9-hemiacetal
33396-29-1

8,9-anhydroerythromycin A 6,9-hemiacetal

N-2-butynyl-8,9-anhydroerythromycin A 6,9-hemiacetal bromide
127955-28-6

N-2-butynyl-8,9-anhydroerythromycin A 6,9-hemiacetal bromide

Conditions
ConditionsYield
In chloroform for 2h; Ambient temperature;100%
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

diethyl 2-(but-2-yn-1-yl)-2-methylmalonate
182809-41-2

diethyl 2-(but-2-yn-1-yl)-2-methylmalonate

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;100%
Stage #1: Diethyl methylmalonate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran at -78℃; for 1h;
97.6%
Stage #1: Diethyl methylmalonate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran at -78 - 20℃;
97.6%
sodium p-hydroxybenzenesulfonate
825-90-1

sodium p-hydroxybenzenesulfonate

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

4-but-2-ynyloxy-benzenesulfonic acid sodium salt

4-but-2-ynyloxy-benzenesulfonic acid sodium salt

Conditions
ConditionsYield
With sodium hydroxide In water; isopropyl alcohol at 70℃; for 15h;100%
With sodium hydroxide In water; isopropyl alcohol at 70℃; for 15h;100%
With sodium hydroxide In water; isopropyl alcohol at 70℃; for 15h;100%
2-tert-butylisoindole-1,3-dione
2141-99-3

2-tert-butylisoindole-1,3-dione

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

N-tert-butyl-2-(2-methyl-buta-2,3-dienoyl)benzamide

N-tert-butyl-2-(2-methyl-buta-2,3-dienoyl)benzamide

Conditions
ConditionsYield
With magnesium; mercury dichloride In tetrahydrofuran at 0℃; for 2h;100%
2-mercaptophenylethane
4410-99-5

2-mercaptophenylethane

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

(2-but-2-ynylsulfanylethyl)benzene

(2-but-2-ynylsulfanylethyl)benzene

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; for 1.5h;100%
Stage #1: 2-mercaptophenylethane With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran at 20℃;
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-(but-2-yn-1-yl)malonate
117500-14-8

diethyl 2-(but-2-yn-1-yl)malonate

Conditions
ConditionsYield
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran; mineral oil for 0.833333h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran; mineral oil for 2h;
100%
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran; mineral oil for 0.833333h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran; mineral oil for 2h;
100%
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran for 0.833333h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran for 2h;
97.6%
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

ethyl cyclohexyl [4-(hydroxyphenyl)sulfanyl]acetate
287393-00-4

ethyl cyclohexyl [4-(hydroxyphenyl)sulfanyl]acetate

ethyl-{[4-(2-butynyloxy)phenyl]sulfanyl}(cyclohexyl)acetate
287393-01-5

ethyl-{[4-(2-butynyloxy)phenyl]sulfanyl}(cyclohexyl)acetate

Conditions
ConditionsYield
100%
With potassium carbonate In acetone Heating;
dimethyl 2-(3,3-dimethoxypropyl)-1,3-propanedioate
53744-52-8

dimethyl 2-(3,3-dimethoxypropyl)-1,3-propanedioate

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

4,4-bis(methoxycarbonyl)-6-octynal dimethyl acetal
828913-58-2

4,4-bis(methoxycarbonyl)-6-octynal dimethyl acetal

Conditions
ConditionsYield
Stage #1: dimethyl 2-(3,3-dimethoxypropyl)-1,3-propanedioate With sodium hydride In tetrahydrofuran at 20℃; for 0.333333h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran at 20℃; for 5h;
100%
dimethyl 2-(2,2-dimethoxyethyl)-1,3-propanedioate
51534-81-7

dimethyl 2-(2,2-dimethoxyethyl)-1,3-propanedioate

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

3,3-bis(methoxycarbonyl)-5-heptynal dimethyl acetal
828913-50-4

3,3-bis(methoxycarbonyl)-5-heptynal dimethyl acetal

Conditions
ConditionsYield
Stage #1: dimethyl 2-(2,2-dimethoxyethyl)-1,3-propanedioate With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran at 20℃; for 4h;
100%
Stage #1: dimethyl 2-(2,2-dimethoxyethyl)-1,3-propanedioate With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: 1-Bromo-2-butyne With sodium iodide In N,N-dimethyl-formamide at 20℃; for 1h;
96%
2-pyrrolidinon
616-45-5

2-pyrrolidinon

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

1-but-2-ynyl-pyrrolidin-2-one

1-but-2-ynyl-pyrrolidin-2-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In tetrahydrofuran for 4h; Heating;100%
piperidin-2-one
675-20-7

piperidin-2-one

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

1-but-2-ynyl-piperidin-2-one

1-but-2-ynyl-piperidin-2-one

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In tetrahydrofuran for 4h; Heating;100%
2-(4-fluoro-benzenesulfonyl)-3-pyridin-3-ylpropionic acid tert-butyl ester

2-(4-fluoro-benzenesulfonyl)-3-pyridin-3-ylpropionic acid tert-butyl ester

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

2-(4-fluoro-benzenesulfonyl)-2-pyridin-3-ylmethyl-hex-4-ynoic acid tert-butyl ester

2-(4-fluoro-benzenesulfonyl)-2-pyridin-3-ylmethyl-hex-4-ynoic acid tert-butyl ester

Conditions
ConditionsYield
100%
100%
C18H16N2O2S

C18H16N2O2S

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

C22H20N2O2S
1147480-13-4

C22H20N2O2S

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 5h;100%
dansylamide
1431-39-6

dansylamide

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

N,N-bis(2-butynyl)-5-(dimethylamino)naphthalene-1-sulfonamide
1264264-16-5

N,N-bis(2-butynyl)-5-(dimethylamino)naphthalene-1-sulfonamide

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 2h; Reflux;100%
methyl 4-hydroxylbenzoate
99-76-3

methyl 4-hydroxylbenzoate

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

methyl 4-(but-2-yn-1-yloxy)benzoate
362705-52-0

methyl 4-(but-2-yn-1-yloxy)benzoate

Conditions
ConditionsYield
With potassium carbonate In butanone at 20℃; for 23h; Reflux;100%
With potassium carbonate In butanone at 20℃; for 23h; Reflux;100%
Stage #1: methyl 4-hydroxylbenzoate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide; mineral oil at 19℃; for 20h; Inert atmosphere;
79%
5-hydroxy-1-(pyrrolidin-1-yl)pentan-1-one
73200-35-8

5-hydroxy-1-(pyrrolidin-1-yl)pentan-1-one

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

5-(but-2-ynyloxy)-1-(pyrrolidin-1-yl)pentan-1-one
1221896-11-2

5-(but-2-ynyloxy)-1-(pyrrolidin-1-yl)pentan-1-one

Conditions
ConditionsYield
Stage #1: 5-hydroxy-1-(pyrrolidin-1-yl)pentan-1-one With sodium hydride In tetrahydrofuran; mineral oil at 0℃; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran; mineral oil at 0 - 20℃; Inert atmosphere;
100%
N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide
1271726-25-0

N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

4-((N-but-2-ynyl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-one
1271726-28-3

4-((N-but-2-ynyl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-one

Conditions
ConditionsYield
Stage #1: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h; Inert atmosphere;
100%
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester
4326-36-7

(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

methyl (S)-2-tert-butoxycarbonylamino-3-(4-but-2-ynyloxy-phenyl)-propionate

methyl (S)-2-tert-butoxycarbonylamino-3-(4-but-2-ynyloxy-phenyl)-propionate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 19h; Inert atmosphere;100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;30%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 19h;
2-Iodophenol
533-58-4

2-Iodophenol

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

1-(but-2-yn-1-yloxy)-2-iodobenzene
1188474-17-0

1-(but-2-yn-1-yloxy)-2-iodobenzene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; Inert atmosphere;100%
With potassium carbonate In acetonitrile at 60℃; for 2h;85%
N-allyl-2-bromo-4,5-dimethoxybenzenesulfonamide
1378317-35-1

N-allyl-2-bromo-4,5-dimethoxybenzenesulfonamide

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

N-allyl-2-bromo-N-(but-2-yn-1-yl)-4,5-dimethoxybenzenesulfonamide

N-allyl-2-bromo-N-(but-2-yn-1-yl)-4,5-dimethoxybenzenesulfonamide

Conditions
ConditionsYield
Stage #1: N-allyl-2-bromo-4,5-dimethoxybenzenesulfonamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1h;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 2h;
100%
Stage #1: N-allyl-2-bromo-4,5-dimethoxybenzenesulfonamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 2h;
94%
N-methyl-4-bromobenzylamine
699-03-6

N-methyl-4-bromobenzylamine

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

N-(4-bromobenzyl)-N-methylbut-2-yn-1-amine hydrochloride

N-(4-bromobenzyl)-N-methylbut-2-yn-1-amine hydrochloride

Conditions
ConditionsYield
Stage #1: N-methyl-4-bromobenzylamine; 1-Bromo-2-butyne With potassium carbonate; potassium iodide In toluene; acetonitrile at 40℃; Sealed tube;
Stage #2: With hydrogenchloride In diethyl ether Sealed tube;
100%
C10H11NO3

C10H11NO3

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

C14H17NO3

C14H17NO3

Conditions
ConditionsYield
With indium; ammonium chloride In tetrahydrofuran at 0 - 20℃;100%
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

3,5-dichlorosalicyclaldehyde
90-60-8

3,5-dichlorosalicyclaldehyde

2-(but-2-yn-1-yloxy)-3,5-dichlorobenzaldehyde

2-(but-2-yn-1-yloxy)-3,5-dichlorobenzaldehyde

Conditions
ConditionsYield
Stage #1: 3,5-dichlorosalicyclaldehyde With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
99.6%
Stage #1: 3,5-dichlorosalicyclaldehyde With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
benzaldehyde
100-52-7

benzaldehyde

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

2-methyl-1-phenylbuta-2,3-dien-1-ol
78808-42-1

2-methyl-1-phenylbuta-2,3-dien-1-ol

Conditions
ConditionsYield
With indium; ammonium chloride In tetrahydrofuran at 0 - 20℃;99%
Stage #1: 1-Bromo-2-butyne With sodium iodide; tin(ll) chloride In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: benzaldehyde In N,N-dimethyl-formamide at 0 - 20℃;
86%
Stage #1: 1-Bromo-2-butyne With sodium iodide; tin(ll) chloride In N,N-dimethyl-formamide at 0℃; for 1.5h;
Stage #2: benzaldehyde In N,N-dimethyl-formamide
80%
nonan-1-al
124-19-6

nonan-1-al

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

3-Methyl-dodeca-1,2-dien-4-ol
78808-47-6

3-Methyl-dodeca-1,2-dien-4-ol

Conditions
ConditionsYield
indium In water Ambient temperature;99%
With gallium; indium In tetrahydrofuran at 25℃; for 1h;75%
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

Ethyl isobutyrate
97-62-1

Ethyl isobutyrate

ethyl 2,2-dimethylhex-4-ynoate
116252-14-3

ethyl 2,2-dimethylhex-4-ynoate

Conditions
ConditionsYield
Stage #1: Ethyl isobutyrate With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran; hexane at -78℃; for 0.75h;
99%
With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium diisopropyl amide In tetrahydrofuran at -10℃;95%
With lithium diisopropyl amide76%
Stage #1: Ethyl isobutyrate With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.75h; Inert atmosphere;
Stage #2: 1-Bromo-2-butyne In tetrahydrofuran; hexane at -78 - 20℃; for 0.4h; Inert atmosphere;
61%
4-methoxy-phenol
150-76-5

4-methoxy-phenol

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

1-(but-2-yn-1-yloxy)-4-methoxybenzene
41580-74-9

1-(but-2-yn-1-yloxy)-4-methoxybenzene

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 6h;99%
With caesium carbonate In N,N-dimethyl-formamide at 20℃;
Stage #1: 4-methoxy-phenol With caesium carbonate In N,N-dimethyl-formamide for 0.333333h;
Stage #2: 1-Bromo-2-butyne In N,N-dimethyl-formamide at 20℃;
1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

ethyl isopropyl [4-(hydroxyphenyl)sulfanyl]acetate
287393-36-6

ethyl isopropyl [4-(hydroxyphenyl)sulfanyl]acetate

ethyl-{[4-(2-butynyloxy)phenyl]sulfanyl}(isopropyl)acetate
287393-37-7

ethyl-{[4-(2-butynyloxy)phenyl]sulfanyl}(isopropyl)acetate

Conditions
ConditionsYield
99%
With potassium carbonate In acetone Heating;
3-(1-{6-[4-(2-ethoxycarbonyl-ethyl)-2,5-dioxo-imidazolidin-1-yl]-hexyl}-2,5-dioxoimidazolidin-4-yl)-propionic acid ethyl ester
892495-95-3

3-(1-{6-[4-(2-ethoxycarbonyl-ethyl)-2,5-dioxo-imidazolidin-1-yl]-hexyl}-2,5-dioxoimidazolidin-4-yl)-propionic acid ethyl ester

1-Bromo-2-butyne
3355-28-0

1-Bromo-2-butyne

3-(3-but-2-ynyl-1-{6-[3-but-2-ynyl-4-(2-ethoxycarbonyl-ethyl)-2,5-dioxo-imidazolidin-1-yl]hexyl}-2,5-dioxo-imidazolidin-4-yl)propionic acid ethyl ester

3-(3-but-2-ynyl-1-{6-[3-but-2-ynyl-4-(2-ethoxycarbonyl-ethyl)-2,5-dioxo-imidazolidin-1-yl]hexyl}-2,5-dioxo-imidazolidin-4-yl)propionic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone Heating;99%
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