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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-Benzofuranol Manufacturer/High quality/Best price/In stock

Cas:13196-10-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Item Quality Standard Test Result Appearance colorless clear liquid colorless clear liquid Assay %

high purity 13196-10-6 5-benzofuranol

Cas:13196-10-6

Min.Order:1 Kilogram

FOB Price: $1.9 / 2.5

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

5-?Benzofuranol

Cas:13196-10-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Benzofuran-5-ol

Cas:13196-10-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 13196-10-6 with competitive price

Cas:13196-10-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

1-benzofuran-5-ol 13196-10-6

Cas:13196-10-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-BENZOFURANOL

Cas:13196-10-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Benzofuranol 13196-10-6

Cas:13196-10-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-BENZOFURANOL CAS:13196-10-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

5-BENZOFURANOL CAS:13196-10-6

Cas:13196-10-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Benzofuranol

Cas:13196-10-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-benzofuran-5-ol

Cas:13196-10-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

cas:13196-10-6

Cas:13196-10-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

1-benzofuran-5-ol

Cas:13196-10-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-benzofuran-5-ol

Cas:13196-10-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Benzofuranol

Cas:13196-10-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

13196-10-6 CAS NO.13196-10-6

Cas:13196-10-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l A

2-CHLORO-4-SULFAMOYLANILINE

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

1-benzofuran-5-ol

Cas:13196-10-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1-benzofuran-5-ol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Other

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5-Hydroxybenzofuran

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

5-Benzofuranol Application:Organic Chemicals

13196-10-6

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

5-Benzofuranol

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

13196-10-6

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

5-Benzofuranol cas 13196-10-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Benzofuranol cas 13196-10-6

Cas:13196-10-6

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

5-methoxybenzofuran
13391-28-1

5-methoxybenzofuran

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
With boron tribromide In dichloromethane at -78 - 20℃; for 2h; Inert atmosphere;89%
With boron tribromide In dichloromethane at -78 - 20℃; for 3h; Inert atmosphere; regioselective reaction;85%
With boron tribromide-dimethyl sulfide complex In chlorobenzene at 130℃; for 12h;80%
5-bromobenzofuran
23145-07-5

5-bromobenzofuran

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; boric acid; palladium diacetate; caesium carbonate In 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Schlenk technique; Inert atmosphere;66%
2,3-dihydro-1-benzofuran-5-ylboronic acid
331834-13-0

2,3-dihydro-1-benzofuran-5-ylboronic acid

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
With water; triethylamine In acetonitrile at 20℃; for 36h; Irradiation;56%
With Oxone; potassium phosphate; 2-(biphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In water at 70℃; for 1h; chemoselective reaction;
2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol
3673-68-5

2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol

A

p-cresol
106-44-5

p-cresol

B

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

C

4-Ethylphenol
123-07-9

4-Ethylphenol

D

p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

E

1-[4-(2-hydroxyethyl)phenoxy]-2-(4'-hydroxyphenyl)ethane
1240059-73-7

1-[4-(2-hydroxyethyl)phenoxy]-2-(4'-hydroxyphenyl)ethane

F

di[2-(4-hydroxyphenyl)]ethyl ether
501123-58-6

di[2-(4-hydroxyphenyl)]ethyl ether

G

C24H34O3

C24H34O3

H

6-tert-butyl-5-hydroxybenzofuran
117516-54-8

6-tert-butyl-5-hydroxybenzofuran

I

phenol
108-95-2

phenol

Conditions
ConditionsYield
at 295 - 298℃; for 22h; Inert atmosphere;A n/a
B n/a
C n/a
D 55%
E n/a
F 40 g
G n/a
H n/a
I n/a
2-nitrofuran
609-39-2

2-nitrofuran

danishefsky's diene
54125-02-9

danishefsky's diene

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
In benzene at 120℃; for 72h; Diels-Alder reaction;50%
(+)-(3S)-3-hydroxy-2,3-dihydrobenzofuran
152560-12-8

(+)-(3S)-3-hydroxy-2,3-dihydrobenzofuran

A

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

B

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran
141977-89-1

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran

C

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

Conditions
ConditionsYield
for 22h; Pseudomonas putida UV4;A 13%
B 4%
C 22%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

A

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

B

(+)-(3S)-3-hydroxy-2,3-dihydrobenzofuran
152560-12-8

(+)-(3S)-3-hydroxy-2,3-dihydrobenzofuran

C

(-)-(3R)-3-hydroxy-2,3-dihydrobenzofuran
152560-17-3

(-)-(3R)-3-hydroxy-2,3-dihydrobenzofuran

Conditions
ConditionsYield
Pseudomonas putida UV4; Yields of byproduct given;A 9%
B n/a
C n/a
Pseudomonas putida UV4; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(-/+)-3-hydroxy-2,3-dihydrobenzofuran
5380-80-3

(-/+)-3-hydroxy-2,3-dihydrobenzofuran

A

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

B

(-)-(4S,5R)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran
141852-40-6, 141977-89-1

(-)-(4S,5R)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran

C

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran
141977-89-1

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran

D

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

Conditions
ConditionsYield
for 20h; Pseudomonas putida UV4; Yield given. Further byproducts given. Title compound not separated from byproducts;A 4%
B n/a
C n/a
D n/a
(-/+)-3-hydroxy-2,3-dihydrobenzofuran
5380-80-3

(-/+)-3-hydroxy-2,3-dihydrobenzofuran

A

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

B

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran
141977-89-1

(+)-(4R,5S)-cis-4,5-dihydroxy-4,5-dihydrobenzofuran

C

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

(+)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

D

(-)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

(-)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

Conditions
ConditionsYield
for 20h; Pseudomonas putida UV4; Further byproducts given. Yields of byproduct given;A 4%
B n/a
C n/a
D n/a
for 20h; Pseudomonas putida UV4; Yield given. Further byproducts given. Title compound not separated from byproducts;A 4%
B n/a
C n/a
D n/a
(-)-(3R)-3-hydroxy-2,3-dihydrobenzofuran
152560-17-3

(-)-(3R)-3-hydroxy-2,3-dihydrobenzofuran

A

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

B

(-)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

(-)-(3S)-3,5-dihydroxy-2,3-dihydrobenzofuran

Conditions
ConditionsYield
for 22h; Pseudomonas putida UV4;A 2%
B 3%
p-methoxyphenoxyacetaldehyde diethyl acetal
69034-13-5

p-methoxyphenoxyacetaldehyde diethyl acetal

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 35 percent / poliphosphoric acid / benzene / 2 h / 100 °C
2: 80 percent / BBr3*SMe2 / chlorobenzene / 12 h / 130 °C
View Scheme
Multi-step reaction with 2 steps
1.1: Amberlyst 15 / toluene / 6 h / Reflux
2.1: boron tribromide / dichloromethane / 2 h / -20 - 20 °C / Inert atmosphere
2.2: 0.25 h / -20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: Amberlyst 15 / toluene / 6 h / Reflux
2.1: boron tribromide / dichloromethane / 2 h / -20 - 20 °C / Inert atmosphere
2.2: 0.25 h / -20 °C / Inert atmosphere
View Scheme
4-methoxy-phenol
150-76-5

4-methoxy-phenol

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / potassium carbonate / dimethylformamide / 3 h / Heating
2: 35 percent / poliphosphoric acid / benzene / 2 h / 100 °C
3: 80 percent / BBr3*SMe2 / chlorobenzene / 12 h / 130 °C
View Scheme
Multi-step reaction with 3 steps
1.1: potassium hydroxide / dimethyl sulfoxide / 0.33 h / 20 °C
1.2: 4 h / 120 °C
2.1: Amberlyst 15 / toluene / 6 h / Reflux
3.1: boron tribromide / dichloromethane / 2 h / -20 - 20 °C / Inert atmosphere
3.2: 0.25 h / -20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1.1: potassium hydroxide / dimethyl sulfoxide / 0.33 h / 20 °C
1.2: 4 h / 120 °C
2.1: Amberlyst 15 / toluene / 6 h / Reflux
3.1: boron tribromide / dichloromethane / 2 h / -20 - 20 °C / Inert atmosphere
3.2: 0.25 h / -20 °C / Inert atmosphere
View Scheme
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Pseudomonas putida UV4
2: 13 percent / 22 h / Pseudomonas putida UV4
View Scheme
Multi-step reaction with 2 steps
1: Pseudomonas putida UV4
2: 2 percent / 22 h / Pseudomonas putida UV4
View Scheme
(-/+)-3-hydroxy-2,3-dihydrobenzofuran
5380-80-3

(-/+)-3-hydroxy-2,3-dihydrobenzofuran

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 13 percent / 22 h / Pseudomonas putida UV4
View Scheme
Multi-step reaction with 2 steps
2: 2 percent / 22 h / Pseudomonas putida UV4
View Scheme
4-methoxy-phenol
150-76-5

4-methoxy-phenol

Bromoacetaldehyde diethyl acetal
2032-35-1

Bromoacetaldehyde diethyl acetal

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Stage #1: 4-methoxy-phenol; Bromoacetaldehyde diethyl acetal With potassium hydroxide
Stage #2:
2-chloro-1-(2-hydroxy-5-methoxyphenyl)ethan-1-one
75717-53-2

2-chloro-1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium acetate / methanol / 1.5 h / Reflux
2: sodium tetrahydroborate; methanol / 0 - 20 °C
3: trifluoroacetic acid / acetonitrile
4: boron tribromide / dichloromethane / 2 h / -60 - 0 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1: sodium acetate / methanol / 1.5 h / Reflux
2: methanol; sodium tetrahydroborate / 0 - 20 °C
3: trifluoroacetic acid / acetonitrile
4: boron tribromide / dichloromethane / 2 h / -60 - 0 °C / Inert atmosphere
View Scheme
5-methoxy-benzofuran-3-one
39581-55-0

5-methoxy-benzofuran-3-one

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; methanol / 0 - 20 °C
2: trifluoroacetic acid / acetonitrile
3: boron tribromide / dichloromethane / 2 h / -60 - 0 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: methanol; sodium tetrahydroborate / 0 - 20 °C
2: trifluoroacetic acid / acetonitrile
3: boron tribromide / dichloromethane / 2 h / -60 - 0 °C / Inert atmosphere
View Scheme
5-methoxy-2,3-dihydro-benzofuran-3-ol
33320-42-2

5-methoxy-2,3-dihydro-benzofuran-3-ol

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trifluoroacetic acid / acetonitrile
2: boron tribromide / dichloromethane / 2 h / -60 - 0 °C / Inert atmosphere
View Scheme
2-[4-(benzyloxy)phenoxy]acetaldehyde diethyl acetal
51343-96-5

2-[4-(benzyloxy)phenoxy]acetaldehyde diethyl acetal

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: polyphosphoric acid / benzene / 2 h / 23 °C / Inert atmosphere; Reflux
2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 23 °C
View Scheme
5-(benzyloxy)benzofuran
92496-27-0

5-(benzyloxy)benzofuran

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 23℃; for 4h;
C13H12BNO5

C13H12BNO5

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
Stage #1: C13H12BNO5 With potassium phosphate; 2-(biphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In water at 80℃; for 0.25h;
Stage #2: With Oxone In water at 70℃; for 1h; chemoselective reaction;
C12H15NO3

C12H15NO3

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water for 2h; Reflux;
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

3-(bromomethyl)pyridine hydrobromide

3-(bromomethyl)pyridine hydrobromide

3-[(1-benzofuran-5-yloxy)methyl]pyridine

3-[(1-benzofuran-5-yloxy)methyl]pyridine

Conditions
ConditionsYield
Stage #1: benzofuran-5-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.333333h;
Stage #2: 3-(bromomethyl)pyridine hydrobromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 18h;
99%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

5-(ethoxymethoxy)benzofuran
1211333-08-2

5-(ethoxymethoxy)benzofuran

Conditions
ConditionsYield
Stage #1: benzofuran-5-ol With sodium ethanolate In ethanol; ethyl acetate at -7.1℃; for 0.0833333h;
Stage #2: ethyl chloromethyl ether In ethanol; ethyl acetate at -14.5 - 20℃;
97%
Stage #1: benzofuran-5-ol With sodium hydride In N,N-dimethyl-formamide; oil at 0 - 20℃;
Stage #2: ethyl chloromethyl ether In N,N-dimethyl-formamide; oil at 0 - 20℃;
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

2-fluoroethyl bromide
762-49-2

2-fluoroethyl bromide

5-(2-fluoroethoxy)-1-benzofuran

5-(2-fluoroethoxy)-1-benzofuran

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 80℃; for 99h;93%
With potassium carbonate In N,N-dimethyl-formamide at 20 - 80℃; for 99h;93%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

5-(methoxymethoxy)-1-benzofuran

5-(methoxymethoxy)-1-benzofuran

Conditions
ConditionsYield
Stage #1: benzofuran-5-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1.5h; Inert atmosphere;
Stage #2: chloromethyl methyl ether In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 3.5h; Inert atmosphere;
89%
Stage #1: benzofuran-5-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1.5h; Inert atmosphere;
Stage #2: chloromethyl methyl ether In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 3.5h;
89%
Stage #1: benzofuran-5-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1.58333h; Inert atmosphere;
Stage #2: chloromethyl methyl ether In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 2h;
89%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

ethyl 4-chloronicotinate
37831-62-2

ethyl 4-chloronicotinate

ethyl 4-(benzofuran-5-yloxy)nicotinate
1618131-46-6

ethyl 4-(benzofuran-5-yloxy)nicotinate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90 - 110℃;86%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

pivaloyl chloride
3282-30-2

pivaloyl chloride

benzofuran-5-yl pivalate

benzofuran-5-yl pivalate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere; Sealed tube;86%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

benzofuran-5-ol
13196-10-6

benzofuran-5-ol

(benzofuran-5-yloxy)trimethyl silane

(benzofuran-5-yloxy)trimethyl silane

Conditions
ConditionsYield
With triethylamine In dichloromethane at -5 - 40℃; Large scale;81.4%
Stage #1: benzofuran-5-ol With triethylamine In dichloromethane at 40℃; Large scale;
Stage #2: chloro-trimethyl-silane In dichloromethane at -5℃; for 1h; Large scale;
81.4%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;290 mg
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(benzofuran-5-yloxy)(tert-butyl)dimethylsilane

(benzofuran-5-yloxy)(tert-butyl)dimethylsilane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h; Inert atmosphere;81%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h;81%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h;81%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

(R)-glycidyl nosylate
115314-14-2, 115314-17-5

(R)-glycidyl nosylate

(R)-5-(oxiran-2-ylmethoxy)benzofuran

(R)-5-(oxiran-2-ylmethoxy)benzofuran

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 14h;78%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

4-bromo-5-hydroxybenzofuran
40432-23-3

4-bromo-5-hydroxybenzofuran

Conditions
ConditionsYield
With N-Bromosuccinimide; diisopropylamine In dichloromethane for 16h; Inert atmosphere; Reflux;70%
With bromine In methanol at -30℃; for 1.5h;
With bromine In methanol at -78℃;2.3 g
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide
145100-51-2

N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide

benzofuran-5-yl triflate

benzofuran-5-yl triflate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;68%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

1-amino-cyclopentanemethanol
3637-61-4

1-amino-cyclopentanemethanol

5-(cyclopentylmethoxy)benzofuran
939050-91-6

5-(cyclopentylmethoxy)benzofuran

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 16h;65%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

2-bromo-2-methylpropanamide
7462-74-0

2-bromo-2-methylpropanamide

2-(benzofuran-5-yloxy)-2-methyl-propionamide
909398-09-0

2-(benzofuran-5-yloxy)-2-methyl-propionamide

Conditions
ConditionsYield
With sodium hydride In 1,4-dioxane at 100℃; for 6h;60%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

1-(tert-butoxycarbonyl)-L-proline
15761-39-4

1-(tert-butoxycarbonyl)-L-proline

2-(benzofuran-5-yl)-1-(tert-butyl)(S)-pyrrolidine-1,2-dicarboxylate

2-(benzofuran-5-yl)-1-(tert-butyl)(S)-pyrrolidine-1,2-dicarboxylate

Conditions
ConditionsYield
With nickel(II) bromide dimethoxyethane; 4,4'-Dimethoxy-2,2'-bipyridin; tetrabutylammomium bromide; potassium carbonate In N,N-dimethyl acetamide at 20℃; for 10h; Inert atmosphere; Glovebox; Electrolysis;60%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

4-(bromomethyl)benzaldehyde
51359-78-5

4-(bromomethyl)benzaldehyde

4-((benzofuran-5-oxy)methyl)benzaldehyde

4-((benzofuran-5-oxy)methyl)benzaldehyde

Conditions
ConditionsYield
Stage #1: benzofuran-5-ol With caesium carbonate In ethanol at 20℃; for 1h;
Stage #2: 4-(bromomethyl)benzaldehyde With potassium iodide In ethanol at 80℃; for 4h;
55.38%
Stage #1: benzofuran-5-ol With caesium carbonate In ethanol at 20℃; for 1h; Williamson Ether Synthesis;
Stage #2: 4-(bromomethyl)benzaldehyde With potassium iodide In ethanol for 4h; Williamson Ether Synthesis; Reflux;
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

chlorobenzene
108-90-7

chlorobenzene

5-hydroxy-2-phenylbenzofuran
7182-29-8

5-hydroxy-2-phenylbenzofuran

Conditions
ConditionsYield
With 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran; diethyl ether at -50℃; for 14h; Sealed tube; Inert atmosphere;53%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

2,3-dihydrobenzofuran-5-ol
40492-52-2

2,3-dihydrobenzofuran-5-ol

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethanol under 2585.81 Torr; for 19h;51%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

nitro-4 hydroxy-5 benzofuranne
87925-17-5

nitro-4 hydroxy-5 benzofuranne

Conditions
ConditionsYield
With Nitrogen dioxide 1.) benzene, 0 deg C, 2 h; 2.) 20 deg C, ethanol;50%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

3-(bromomethyl)benzaldehyde
82072-23-9

3-(bromomethyl)benzaldehyde

3-((benzofuran-5-oxy)methyl)benzaldehyde

3-((benzofuran-5-oxy)methyl)benzaldehyde

Conditions
ConditionsYield
Stage #1: benzofuran-5-ol With caesium carbonate In ethanol at 20℃; for 1h;
Stage #2: 3-(bromomethyl)benzaldehyde With potassium iodide In ethanol at 80℃; for 4h;
50%
Stage #1: benzofuran-5-ol With caesium carbonate In ethanol at 20℃; for 1h; Williamson Ether Synthesis;
Stage #2: 3-(bromomethyl)benzaldehyde With potassium iodide In ethanol for 4h; Williamson Ether Synthesis; Reflux;
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

[2-(1-benzofuran-5-yloxy)ethyl]dimethylamine

[2-(1-benzofuran-5-yloxy)ethyl]dimethylamine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 60℃; for 21h;44%
benzofuran-5-ol
13196-10-6

benzofuran-5-ol

Ethyl N-phenylformimidate
6780-49-0

Ethyl N-phenylformimidate

5-Hydroxy-4-(N-phenyliminomethyl)benzofuran

5-Hydroxy-4-(N-phenyliminomethyl)benzofuran

Conditions
ConditionsYield
for 2h; Heating;29%

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