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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Colorless or yellowish liquid Conform Assay(GC) 99.00%min

High purity Various Specifications 2,3-Dihydrobenzofuran CAS:496-16-2

Cas:496-16-2

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,3-Dihydrobenzofuran supplier in China

Cas:496-16-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

2,3-Dihydrobenzofuran CAS NO.496-16-2

Cas:496-16-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,3-dihydrobenzofuran

Cas:496-16-2

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

2,3-Dihydrobenzofuran CAS 496-16-2 Coumaran CAS no 496-16-2 2,3-Dihydro-1-benzofuran 2,3-Dihydrobenzofuran CAS 496-16-2 2,3-Dihydro-1-benzofuran IN Stock CAS 496-16-2 2,3-Dihydro-1-benzofuran 2,3-Dihydrobenzofuran COA TDS price MSDS Benzamid

2,3-Dihydrobenzofuran CAS 496-16-2 Coumaran CAS no 496-16-2 2,3-Dihydro-1-benzofuran

Cas:496-16-2

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--496-16-2--2,3-Dihydrobenzofuran factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business r

TIANFUCHEM--496-16-2--2,3-Dihydrobenzofuran factory price

Cas:496-16-2

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 496-16-2 with best quality

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,3-Dihydrobenzofuran CAS NO.496-16-2

Cas:496-16-2

Min.Order:10 Kilogram

FOB Price: $40.0 / 50.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2,3-Dihydrobenzofuran/ LIDE PHARMA- Factory supply / Best price

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Light yellowish liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port of China

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

2,3-Dihydrobenzofuran CAS:496-16-2 API Manufacturer

Cas:496-16-2

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3-Dihydrobenzofuran 496-16-2

Cas:496-16-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:Clear colorless liquid Storage:Refer to COA / M

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediates, 2,3-Dihydrobenzofuran CAS:496-16-2

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $210.0 / 240.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2,3-Dihydrobenzofuran CAS:496-16-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

2,3-Dihydrobenzofuran CAS:496-16-2

Cas:496-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

2,3-Dihydrobenzofuran Product Name: 2,3-Dihydrobenzofuran Synonyms: 2,3-Dihydro-1-benzofuran;2,3-dihydro-benzofura;Coumaran (2,3-dihydrobenzofuran);Dihydrobenzofuran;Dihydrocoumarone;Kumaran;2,3-DIHYDROBENZO[B]FURAN;2,3-DIHYDROBENZOFURAN CAS:

2,3-Dihydrobenzofuran Manufactuered in China best quality

Cas:496-16-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcin

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2,3-(Dihydrobenzofuran)-3-Dihydrobenzofuran cas no.496-16-2 0.98

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS496-16-2 2,3-Dihydrobenzofuran

Cas:496-16-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,3-Dihydrobenzofurane

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

2,3-Dihydrobenzo[b]furan

Cas:496-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,3-Dihydrobenzofuran/High quality/Best price

Cas:496-16-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

1-benzofurane
271-89-6

1-benzofurane

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With methanol; palladium diacetate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In dichloromethane at 25℃; for 12h; Sealed tube; Inert atmosphere; chemoselective reaction;99%
With hydrogen In methanol at 80 - 90℃; under 750.075 - 22502.3 Torr; Reagent/catalyst; Autoclave;97.8%
With ethanol; (BQ‑NCOP)IrHCl; sodium t-butanolate at 60℃; for 5h; Inert atmosphere; Schlenk technique; Sealed tube; chemoselective reaction;96%
2-(2-iodophenyl)ethan-1-ol
26059-40-5

2-(2-iodophenyl)ethan-1-ol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With copper(l) iodide; sodium t-butanolate In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Schlenk technique; Inert atmosphere; Molecular sieve;99%
Multi-step reaction with 3 steps
1.1: triphenylphosphine; iodine; 1H-imidazole / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere; Darkness
2.1: silver(l) oxide / N,N-dimethyl-formamide / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 - 20 °C / Inert atmosphere
View Scheme
2-(2-chlorophenyl)-1-ethanol
19819-95-5

2-(2-chlorophenyl)-1-ethanol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With Ru/Al2O3; potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1.5h; Temperature; Microwave irradiation;96.2%
With copper(l) iodide; 8-quinolinol; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 20 - 120℃; Inert atmosphere;82%
With racemic-2-(di-tert-butylphosphino)-1,1′-binaphthyl; palladium diacetate; caesium carbonate In toluene at 50℃; for 23h;72%
With racemic-2-(di-tert-butylphosphino)-1,1′-binaphthyl; palladium diacetate; caesium carbonate In toluene at 50℃; for 23h;72%
With potassium phosphate; C22H28NP; palladium diacetate In toluene at 60℃; for 20h;51 % Chromat.
2-bromophenylethyl alcohol
1074-16-4

2-bromophenylethyl alcohol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With copper(l) iodide; lithium tert-butoxide In 1,4-dioxane at 100℃;96%
With racemic-2-(di-tert-butylphosphino)-1,1′-binaphthyl; palladium diacetate; caesium carbonate In toluene at 50℃; for 26h;87%
With racemic-2-(di-tert-butylphosphino)-1,1′-binaphthyl; palladium diacetate; caesium carbonate In toluene at 50℃; for 26h;87%
2-(2-hydroxyphenyl)ethanol
7768-28-7

2-(2-hydroxyphenyl)ethanol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With sodium methylate In carbonic acid dimethyl ester; acetonitrile for 2h; Inert atmosphere;95%
With 1,8-diazabicyclo[5.4.0]undec-7-ene; carbonic acid dimethyl ester at 90℃; for 8h; Reagent/catalyst; Time;93%
Stage #1: 2-(2-hydroxyphenyl)ethanol With sodium hydride In mineral oil at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: With trimethyl phosphite In mineral oil at 20℃; for 24h; Inert atmosphere;
90%
1-benzofurane
271-89-6

1-benzofurane

1,4,4a,9a-tetrahydro-fluorene
52652-40-1

1,4,4a,9a-tetrahydro-fluorene

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

9H-fluorene
86-73-7

9H-fluorene

Conditions
ConditionsYield
palladium on activated carbon at 250℃; for 2h;A 92%
B 95%
1-benzofurane
271-89-6

1-benzofurane

1,2,3,4-tetrahydro-9H-fluorene
17057-95-3

1,2,3,4-tetrahydro-9H-fluorene

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

9H-fluorene
86-73-7

9H-fluorene

Conditions
ConditionsYield
A 92%
B n/a
1-iodo-2-(2-iodo-ethoxy)-benzene

1-iodo-2-(2-iodo-ethoxy)-benzene

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
Stage #1: 1-iodo-2-(2-iodo-ethoxy)-benzene With isopropylmagnesium chloride In tetrahydrofuran at -30℃; for 1h;
Stage #2: In tetrahydrofuran at 25℃; for 2h;
Stage #3: In tetrahydrofuran
87%
2-(2-Bromoethyl)phenol
57027-75-5

2-(2-Bromoethyl)phenol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 3h; Heating;86%
With sodium hydroxide; benzene
With water
2-(2-bromophenoxy)ethyl 4-methylbenzenesulfonate
94897-00-4

2-(2-bromophenoxy)ethyl 4-methylbenzenesulfonate

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With copper(l) iodide; lithium methanolate; magnesium In tetrahydrofuran at 0℃; for 24h; Inert atmosphere; Schlenk technique;85%
2-(2-hydroxyphenyl)ethanol
7768-28-7

2-(2-hydroxyphenyl)ethanol

Vilsmeier reagent
3724-43-4, 149409-22-3

Vilsmeier reagent

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With triethylamine In dichloromethane Ambient temperature;80%
1-(2-bromoethoxy)-2-iodobenzene
57056-94-7

1-(2-bromoethoxy)-2-iodobenzene

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
Stage #1: 1-(2-bromoethoxy)-2-iodobenzene With isopropylmagnesium chloride In tetrahydrofuran at -30℃; for 1h;
Stage #2: In tetrahydrofuran at 25℃; for 2h;
Stage #3: In tetrahydrofuran
79%
2-bromophenyl 2-chloroethyl ether
64010-12-4

2-bromophenyl 2-chloroethyl ether

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

2-hydroxybromobenzene
95-56-7

2-hydroxybromobenzene

C

phenol
108-95-2

phenol

Conditions
ConditionsYield
With magnesium; ethylene dibromide In tetrahydrofuranA 76%
B n/a
C n/a
5-methyl-1,10-phenanthroline
3002-78-6

5-methyl-1,10-phenanthroline

2-bromophenylethyl alcohol
1074-16-4

2-bromophenylethyl alcohol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With CuI; caesium carbonate In dodecane; toluene72%
1-(2-bromoethoxy)-2-bromobenzene
18800-28-7

1-(2-bromoethoxy)-2-bromobenzene

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -100 - -95℃; for 0.5h;69%
With diethyl ether; sodium
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With aluminium(III) triflate; tris(2,4-pentanedionato)ruthenium(III); hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In tetrahydrofuran at 160℃; under 45603.1 Torr; for 12h; Autoclave;65%
Multi-step reaction with 2 steps
1: Lawesson's reagent / toluene / Heating
2: Raney nickel / diethyl ether / 1.) -15 deg C, 2.) -10 deg C, 2 min
View Scheme
2-(2-iodophenyl)ethyl tert-butyl peroxide
1592933-65-7

2-(2-iodophenyl)ethyl tert-butyl peroxide

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 1h; Inert atmosphere;58%
2-(2-hydroxyphenyl)ethanol
7768-28-7

2-(2-hydroxyphenyl)ethanol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

2-(2'-hydrophenyl)ethyl methyl carbonate

2-(2'-hydrophenyl)ethyl methyl carbonate

Conditions
ConditionsYield
With sodium methylate for 7h; Reflux; Inert atmosphere;A 55%
B 31%
With sodium methylate at 90℃; for 24h;A 6%
B 21%
2-aminophenethyl alcohol
5339-85-5

2-aminophenethyl alcohol

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

2-(2-hydroxyphenyl)ethanol
7768-28-7

2-(2-hydroxyphenyl)ethanol

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite at 0 - 50℃; for 1h;A 35%
B 50%
2-methoxyphenethyl alcohol
7417-18-7

2-methoxyphenethyl alcohol

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

2-(2-Bromoethyl)phenol
57027-75-5

2-(2-Bromoethyl)phenol

Conditions
ConditionsYield
With hydrogen bromide; acetic acidA 36%
B 46%
1-benzofurane
271-89-6

1-benzofurane

A

o-Hydroxyethylbenzene
90-00-6

o-Hydroxyethylbenzene

B

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With 15-crown-5; sodium; isopropyl alcohol In tetrahydrofuran at 0℃; for 0.0833333h; Birch Reduction; chemoselective reaction;A 42%
B 39%
With ethanol; sodium
With ethanol; sodium
With 15-crown-5; sodium In tetrahydrofuran; isopropyl alcohol; mineral oil at 0℃; for 0.0833333h; Inert atmosphere; Overall yield = 75 %; Overall yield = 45 mg;
1-bromo-2-methoxy-3-methylbenzene
52200-69-8

1-bromo-2-methoxy-3-methylbenzene

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With palladium(0)bis(tricyclohexylphosphine); cesium pivalate In toluene at 140℃; for 16h; Inert atmosphere; Sealed tube; Glovebox;40%
1-benzofurane
271-89-6

1-benzofurane

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

4,7-dihydrobenzofuran
99636-24-5

4,7-dihydrobenzofuran

Conditions
ConditionsYield
With sodium In methanol; diethyl ether; ammonia for 0.166667h;A 34%
B 36%
With tetrabutylammonium tetrafluoroborate In tetrahydrofuran; water at 0℃; electrolysis (mercury cathode, platinum flag anode, silver wire reference electrode, constant current 4-32 mA cm-2); Yield given. Yields of byproduct given;
3,4-epoxy-chroman
6538-94-9

3,4-epoxy-chroman

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
In cyclohexane for 6h; Ambient temperature; Irradiation;36%
(Trimethylsilyl)(o-methoxyphenyl)methanol
75311-63-6

(Trimethylsilyl)(o-methoxyphenyl)methanol

A

1-benzofurane
271-89-6

1-benzofurane

B

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
In benzene at 600℃;A 16%
B 28%
[(2-Methoxy-phenyl)-phenylmethanesulfonyl-methylene]-triphenyl-λ5-phosphane
134749-74-9

[(2-Methoxy-phenyl)-phenylmethanesulfonyl-methylene]-triphenyl-λ5-phosphane

A

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

B

(E)-2-methoxystilbene
52805-92-2

(E)-2-methoxystilbene

C

(Z)-1-(2-methoxyphenyl)-2-phenylethene
1898-14-2

(Z)-1-(2-methoxyphenyl)-2-phenylethene

D

1,1'-(1,2-ethanediyl)bisbenzene
103-29-7

1,1'-(1,2-ethanediyl)bisbenzene

Conditions
ConditionsYield
at 600℃; under 0.001 - 0.1 Torr; for 1h; Yields of byproduct given. Title compound not separated from byproducts;A 7%
B n/a
C n/a
D 11 % Spectr.
2-Phenoxyethanol
122-99-6

2-Phenoxyethanol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With zinc(II) chloride
With manganese(ll) chloride; zinc(II) chloride at 200℃; for 3h; Temperature;
1-(2-bromoethoxy)-2-chlorobenzene
18800-26-5

1-(2-bromoethoxy)-2-chlorobenzene

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With diethyl ether; sodium
2-aminophenethyl alcohol
5339-85-5

2-aminophenethyl alcohol

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite Erwaermen der Diazoniumsalz-Loesung mit Natiumhydrogencabonat;
Multi-step reaction with 2 steps
1: 50 percent / aq. sodium nitrite, conc. sulfuric acid / 1 h / 0 - 50 °C
2: 75 percent / alumina-silica / 1,2-dimethoxy-ethane / 1 h / 250 °C
View Scheme
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

5-bromo-2,3-dihydrobenzo[b]furan
66826-78-6

5-bromo-2,3-dihydrobenzo[b]furan

Conditions
ConditionsYield
With bromine100%
With iron(III) chloride; N-Bromosuccinimide; 1-butyl-3-methylimidazolium trifluoromethanesulfonimide In toluene at 40℃; regioselective reaction;98%
With bromine In dichloromethane for 0.5h; Ambient temperature;96%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2,3-dihydro-benzofuran-5-carbaldehyde
55745-70-5

2,3-dihydro-benzofuran-5-carbaldehyde

Conditions
ConditionsYield
With trichlorophosphate at 70 - 90℃; for 9.5h;100%
With trichlorophosphate at 70 - 90℃; for 9.5h;100%
Stage #1: 2.3-dihydrobenzofuran; N,N-dimethyl-formamide With trichlorophosphate at 30 - 70℃;
Stage #2: With water In N,N-dimethyl-formamide at 20℃; for 1h;
98%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2,3-dihydro-benzofuran-5-carbaldehyde
55745-70-5

2,3-dihydro-benzofuran-5-carbaldehyde

Conditions
ConditionsYield
With trichlorophosphate In water; N,N-dimethyl-formamide100%
With trichlorophosphate In water; N,N-dimethyl-formamide100%
With sodium hydrogencarbonate; trichlorophosphate In N,N-dimethyl-formamide94%
Multi-step reaction with 2 steps
1: 100 percent / Br2
2: 98 percent / n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C
View Scheme
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2,3-dihydrobenzofuran-5-sulfonyl chloride
115010-11-2

2,3-dihydrobenzofuran-5-sulfonyl chloride

Conditions
ConditionsYield
Stage #1: 2.3-dihydrobenzofuran With sulfur trioxide-N,N-dimethylformamide complex In 1,2-dichloro-ethane at 85℃; for 1h;
Stage #2: With thionyl chloride In 1,2-dichloro-ethane at 20 - 75℃; for 1h;
100%
Stage #1: 2.3-dihydrobenzofuran With sulfur trioxide-N,N-dimethylformamide complex In 1,2-dichloro-ethane at 85℃; for 1h;
Stage #2: With thionyl chloride In 1,2-dichloro-ethane at 20 - 75℃; for 1h;
100%
In 1,2-dichloro-ethane94%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

acetyl chloride
75-36-5

acetyl chloride

1-(2,3-dihydrobenzofuran-5-yl)ethanone
90843-31-5

1-(2,3-dihydrobenzofuran-5-yl)ethanone

Conditions
ConditionsYield
aluminum (III) chloride In dichloromethane at -10℃; for 0.5h;99%
With aluminum (III) chloride In dichloromethane at -10℃; for 0.5h;99%
With aluminum (III) chloride In dichloromethane at -10℃; for 3h;97%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

5-iodo-2,3-dihydro-1-benzofuran
132464-84-7

5-iodo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With N-iodo-succinimide; silver(I) triflimide In dichloromethane at 36℃; for 1h; Darkness;99%
With indium(III) triflate; N-iodo-succinimide In acetonitrile at 23℃; for 8h; Inert atmosphere; Darkness;92%
With iron(III) chloride; N-iodo-succinimide; 1-butyl-3-methylimidazolium trifluoromethanesulfonimide at 36℃; for 1h; Inert atmosphere;91%
triethylsilane
617-86-7

triethylsilane

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

triethyl-(2-ethyl-phenoxy)-silane

triethyl-(2-ethyl-phenoxy)-silane

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate In dichloromethane at 20℃; for 20h; silylation;99%
With tris(pentafluorophenyl)borate In dichloromethane at 20℃; for 20h; Reduction; dehydrocondensation;99%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

2,3-dihydrobenzofuran-5-sulfonyl chloride
115010-11-2

2,3-dihydrobenzofuran-5-sulfonyl chloride

Conditions
ConditionsYield
With thionyl chloride In water99%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2-trimethylsilyl ethane sulfonic acid azide
871949-46-1

2-trimethylsilyl ethane sulfonic acid azide

C13H21NO3SSi

C13H21NO3SSi

Conditions
ConditionsYield
Stage #1: 2.3-dihydrobenzofuran; 2-trimethylsilyl ethane sulfonic acid azide In neat (no solvent) at -10℃; for 0.5h; Schlenk technique; Inert atmosphere; Molecular sieve;
Stage #2: With C61H40F4N2O3Ru In neat (no solvent) at -10℃; for 2h; Schlenk technique; Inert atmosphere; Molecular sieve; enantioselective reaction;
99%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan
402503-13-3

2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan

Conditions
ConditionsYield
With C25H40O2P2Ru In octane at 150℃; for 12h; Inert atmosphere;99%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

propionyl chloride
79-03-8

propionyl chloride

1-(2,3-dihydrobenzofuran-5-yl)propan-1-one
68660-11-7

1-(2,3-dihydrobenzofuran-5-yl)propan-1-one

Conditions
ConditionsYield
Stage #1: propionyl chloride; aluminum (III) chloride In dichloromethane at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2.3-dihydrobenzofuran In dichloromethane at 0℃; Inert atmosphere;
98%
With aluminum (III) chloride In dichloromethane at 0 - 20℃; for 1h;80%
With tin(IV) chloride In benzene at 30℃; for 24h; Friedel-Crafts acylation;66%
With carbon disulfide; aluminium trichloride
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2,3-dihydrobenzofuran-5-sulfonic acid

2,3-dihydrobenzofuran-5-sulfonic acid

Conditions
ConditionsYield
With sulfur trioxide In nitromethane at 0℃; for 1h;98%
With sulfur trioxide In nitromethane at 0℃;
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2,3-Dihydro-benzofuran-5,7-disulfonic acid

2,3-Dihydro-benzofuran-5,7-disulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 20℃; for 3600h; other reagent; other solvent; other temp;98%
With sulfur trioxide In nitromethane at 0℃; excess of reagent;
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

norbornene
498-66-8

norbornene

7-(bicyclo[2.2.1]hept-2-yl)-2,3-dihydro-1-benzofuran

7-(bicyclo[2.2.1]hept-2-yl)-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With (C5H5)Y(CH2C6H4NMe2-o)2; trityl tetrakis(pentafluorophenyl)borate In toluene at 70℃; for 24h; Inert atmosphere; Glovebox; regioselective reaction;98%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

benzoic acid
65-85-0

benzoic acid

(2,3-dihydrobenzofuran-5-yl)(phenyl)methanone
115063-19-9

(2,3-dihydrobenzofuran-5-yl)(phenyl)methanone

Conditions
ConditionsYield
With trifluoroacetic acid; trifluoroacetic anhydride at 20℃; for 12h; Friedel-Crafts Acylation; Inert atmosphere;98%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

4-Methoxybenzenethiol
696-63-9

4-Methoxybenzenethiol

(2,3-dihydro-1-benzofuran-5-yl)(4′-methoxyphenyl)sulfane

(2,3-dihydro-1-benzofuran-5-yl)(4′-methoxyphenyl)sulfane

Conditions
ConditionsYield
With tetrabutylammonium acetate for 4.5h; Electrolysis; Inert atmosphere; Sealed tube; regioselective reaction;97%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

bis(2,2,2-trichloroethyl) hydrazino-1,2-dicarboxylate
38858-02-5

bis(2,2,2-trichloroethyl) hydrazino-1,2-dicarboxylate

1-(5-dihydrobenzofuranyl)-1,2-hydrazinedicarboxylic acid bis(2,2,2-trichloroethyl) ester
197590-43-5

1-(5-dihydrobenzofuranyl)-1,2-hydrazinedicarboxylic acid bis(2,2,2-trichloroethyl) ester

Conditions
ConditionsYield
With zinc(II) chloride In dichloromethane at 20℃;96.6%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

5-Chloro-2,3-dihydrobenzo[b]furan
76429-69-1

5-Chloro-2,3-dihydrobenzo[b]furan

Conditions
ConditionsYield
With N-chloro-succinimide; 2,2,6,6-tetramethylpiperidin-1-oxoammonium trifluoromethanesulfonate In chloroform at 25℃; for 12h; Reagent/catalyst; Schlenk technique;96%
With iron(III) chloride; N-chloro-succinimide; 1-butyl-3-methylimidazolium trifluoromethanesulfonimide In tetrahydrofuran at 60℃; for 18h; Inert atmosphere; regioselective reaction;86%
With N-chloro-succinimide; zirconium(IV) chloride In dichloromethane at 20℃; for 12h;
With N-chloro-succinimide; zirconium(IV) chloride In dichloromethane at 20℃; for 12h; Conversion of starting material;
With N-chloro-succinimide; acetic acid In acetonitrile at 10 - 35℃; for 48h;2.28 g
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

acetic anhydride
108-24-7

acetic anhydride

1-(2,3-dihydrobenzofuran-5-yl)ethanone
90843-31-5

1-(2,3-dihydrobenzofuran-5-yl)ethanone

Conditions
ConditionsYield
With Hβ zeolite (Si:Al 12.5) at 120℃; for 1.5h;95%
With trifluoroacetic acid at 20℃; for 1.5h; Friedel-Crafts Acylation;91%
With zinc(II) chloride at 95 - 105℃; for 10h;
With zinc(II) chloride at 95 - 105℃; for 10h;
3,5-bis(trifluoromethyl)phenyl azide

3,5-bis(trifluoromethyl)phenyl azide

2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

C16H11F6NO

C16H11F6NO

Conditions
ConditionsYield
With chloro[5,10,15,20-tetrakis(4-dimethylamino-2,3,5,6-tetrafluorophenyl)porphyrinate]iron(III) In 1,2-dichloro-ethane at 120℃; for 12h; Schlenk technique; Inert atmosphere; Molecular sieve; regioselective reaction;95%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

2,3-dihydrobenzofuran-7-sulfonyl chloride
953408-82-7

2,3-dihydrobenzofuran-7-sulfonyl chloride

Conditions
ConditionsYield
In 1,2-dichloro-ethane94%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

1-(2,3-dihydrobenzofuran-5-yl)ethanone
90843-31-5

1-(2,3-dihydrobenzofuran-5-yl)ethanone

Conditions
ConditionsYield
Stage #1: acetyl chloride With aluminum (III) chloride In dichloromethane at -10℃; for 0.25h;
Stage #2: 2.3-dihydrobenzofuran In dichloromethane at -10℃; for 0.5h;
Stage #3: With hydrogenchloride In dichloromethane; water at 0℃; for 2h;
94%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

5,7-Dibromo-2,3-dihydrobenzofuran
123266-59-1

5,7-Dibromo-2,3-dihydrobenzofuran

Conditions
ConditionsYield
With bromine; sodium thiosulfate In dichloromethane; acetic acid93%
With iodine pentoxide; potassium bromide In water at 20℃; for 23h; regioselective reaction;89%
With bromine; sodium thiosulfate In chloroform87%
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

5-Chlorovaleroyl chloride
1575-61-7

5-Chlorovaleroyl chloride

5-Chloro-1-(2,3-dihydro-1-benzofuran-5-yl)-1-pentanone

5-Chloro-1-(2,3-dihydro-1-benzofuran-5-yl)-1-pentanone

Conditions
ConditionsYield
Stage #1: 2.3-dihydrobenzofuran; aluminum (III) chloride In toluene at 20 - 30℃; for 0.5h;
Stage #2: 5-Chlorovaleroyl chloride In toluene at -5 - 5℃; for 1h;
92.8%

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