In stock Contract customization Low Temperature Reactions Fluorine Chemistry Hydrogenation Nitration Chlorination Appearance:Colourless or light yellow liquid Storage:cool and dry warehouse Package:200KG/Drum Application:Used in pharmaceu
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/1597.html Product Name 5-Chlorovaleryl chloride CAS No. 1575-61-7
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inquiryName: 5-Chlorovaleryl chloride Synonyms: 5-Choropentanoyl chloride CAS: 1575-61-7 MF: C5H8Cl2O Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Organic synthesis Transportation:By
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inquiryHangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting 5-Chlorovaleryl chloride (5-CVC) CAS:1575-61-7, Please contact us by email freely. We are leading exporter in China. If you really n
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inquiryHigh quality 5-Chlorovaleryl chloride CAS 1575-61-7 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a st
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiry5-Chlorovaleryl chloride CAS 1575-61-7 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assem
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inquiry1575-61-7 99%Appearance:white powder Storage:keep cold Package:according to customers' requirements Application:Pharmaceutical intermediates 1575-61-7 Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or acco
Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in
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Cas:1575-61-7
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inquiryProduct Name: 5-Chlorovaleryl chloride CAS: 1575-61-7 MF: C5H8Cl2O MW: 155.02 EINECS: 216-403-1 Mol File: 1575-61-7.mol 5-Chlorovaleryl chloride Structure 5-Chlorovaleryl chloride Chemical Properties Boiling point 38-39 °C
Cas:1575-61-7
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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inquiryConditions | Yield |
---|---|
With thionyl chloride for 3h; Heating / reflux; | 97% |
With thionyl chloride for 3h; Heating / reflux; | 97% |
With thionyl chloride for 3h; Heating / reflux; | 97% |
3,4,5,6-tetrahydro-2H-pyran-2-one
phosgene
3-Methylpyridine
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With hydrogenchloride | 81% |
n-valeryl chloride
A
2-chloropentanoyl chloride
B
4-chloropentanoyl chloride
C
5-Chlorovaleroyl chloride
D
3-chloro-valeryl chloride
Conditions | Yield |
---|---|
With phenylchloroiodonium chloride In tetrachloromethane at 30℃; Product distribution; Mechanism; Irradiation; relative rate const., the correlation analysis, subst. phenylchloroiodonium chloride as reagents; | |
With chlorine In neat (no solvent) Product distribution; Ambient temperature; liquid phase chlorination of the aliphatic C5-carboxylic acids and their chlorides, methyl esters and chloromethyl esters, relative reactivity of each hydrogen atoms; | |
With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile) In tetrachloromethane Heating; Title compound not separated from byproducts; |
n-valeryl chloride
A
4-chloropentanoyl chloride
B
5-Chlorovaleroyl chloride
C
3-chloro-valeryl chloride
Conditions | Yield |
---|---|
With chlorine In benzene at 20℃; Product distribution; other solvents; |
chlorine
n-valeryl chloride
A
2-chloropentanoyl chloride
B
4-chloropentanoyl chloride
C
5-Chlorovaleroyl chloride
D
3-chloro-valeryl chloride
Conditions | Yield |
---|---|
at 20℃; im UV-Licht; | |
at 125℃; im UV-Licht; |
chlorine
n-valeryl chloride
benzene
A
2-chloropentanoyl chloride
B
4-chloropentanoyl chloride
C
5-Chlorovaleroyl chloride
D
3-chloro-valeryl chloride
Conditions | Yield |
---|---|
at 20℃; im UV-Licht; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: concentrated aqueous hydrochloric acid 2: thionyl chloride View Scheme |
3,4,5,6-tetrahydro-2H-pyran-2-one
phosgene
1,3,4-trimethylimidazolidin-2-one
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
---|---|
With hydrogenchloride |
3,4,5,6-tetrahydro-2H-pyran-2-one
phosgene
mepiquat chloride
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
---|---|
With Dichloromethyl methyl ether; zinc(II) chloride at 60℃; for 2h; |
sodium cyanide
1,4-dichlorobutane
A
5-Chlorovaleroyl chloride
B
Adipic acid dichloride
Conditions | Yield |
---|---|
Stage #1: sodium cyanide; 1,4-dichlorobutane With tetrabutylammomium bromide In water at 80 - 85℃; for 6h; Large scale; Stage #2: With hydrogenchloride In water at 55 - 70℃; for 5h; Large scale; Stage #3: With thionyl chloride at 20 - 30℃; for 18h; Large scale; | A 422 kg B 163 kg |
5-Chlorovaleroyl chloride
6,12-bis(benzyloxy)-7-oxo-6,12-diazadodecanenitrile
17-chloro-6,12-bis(benzyloxy)-7,13-dioxo-6,12-diazaheptadecanenitrile
Conditions | Yield |
---|---|
With sodium hydroxide In dichloromethane Ambient temperature; | 100% |
5-Chlorovaleroyl chloride
5-fluoro-2-phenoxyaniline
5-chloro-N-(5-fluoro-2-phenoxy-phenyl)-pentanamide
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 20 - 25℃; for 1.5h; | 100% |
5-chloro-thiophene-2-carboxylic acid-N-({1-[4-amino-3-methyl-phenyl]-1H-imidazol-4-yl}-methyl)-amide
5-Chlorovaleroyl chloride
5-chloro-thiophene-2-carboxylic acid-N-({1-[4-({4-chloro-butyl-carbonyl}-amino)-3-methyl-phenyl]-1H-imidazol-4-yl}-methyl)-amide
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; for 16h; | 100% |
5-Chlorovaleroyl chloride
3-amino-5-nitro-benzoic acid methyl ester
3-(4-chloropentanoylamino)-5-nitrobenzoic acid methyl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; | 100% |
dichloromethane
5-Chlorovaleroyl chloride
1,4-dihydro-4-(3-aminophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylic acid,dimethyl ester
Conditions | Yield |
---|---|
In tetrahydrofuran; water; ethyl acetate | 100% |
In tetrahydrofuran; water; ethyl acetate | 100% |
In tetrahydrofuran; water; ethyl acetate | 100% |
5-Chlorovaleroyl chloride
[cis-4-amino-1-(3-chlorophenyl)-cyclohexylmethyl]-carbamic acid tert butyl ester
C23H34Cl2N2O3
Conditions | Yield |
---|---|
With sodium carbonate In chloroform; water at 20℃; for 0.75h; | 100% |
Conditions | Yield |
---|---|
In dichloromethane at 20℃; | 100% |
Conditions | Yield |
---|---|
With aluminum (III) chloride In dichloromethane at 0 - 20℃; for 1h; | 100% |
5-Chlorovaleroyl chloride
(6R,7R)-tert-butyl 6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; | 100% |
5-Chlorovaleroyl chloride
methyl pyrrolidine-2-carboxylate hydrochloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere; | 99% |
Stage #1: m-Anisidine With sodium hydride In tetrahydrofuran; mineral oil for 6h; Inert atmosphere; Stage #2: 5-Chlorovaleroyl chloride In tetrahydrofuran; mineral oil at 20℃; for 6h; Inert atmosphere; | 72% |
SCP-1
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With trifluorormethanesulfonic acid In acetonitrile at 20℃; for 1h; Friedel-Crafts Acylation; | 99% |
5-Chlorovaleroyl chloride
(1S,3S)-3-Benzyloxy-cyclohexylamine
5-Chloro-pentanoic acid ((1S,3S)-3-benzyloxy-cyclohexyl)-amide
Conditions | Yield |
---|---|
With potassium carbonate In tetrahydrofuran; water for 0.5h; Ambient temperature; | 98% |
5-Chlorovaleroyl chloride
methoxybenzene
5-chloro-1-(4-methyloxyphenyl)pentan-1-one
Conditions | Yield |
---|---|
Stage #1: 5-Chlorovaleroyl chloride With aluminum (III) chloride In dichloromethane at 0℃; for 0.166667h; Stage #2: methoxybenzene In dichloromethane at 0 - 20℃; for 1h; | 98% |
With aluminium trichloride Acylation; | 69% |
1H-imidazole
5-Chlorovaleroyl chloride
1-(5-chloro-pentanoyl)-1H-imidazole
Conditions | Yield |
---|---|
In tetrahydrofuran at 18 - 25℃; | 98% |
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 4 - 20℃; for 2h; | 98% |
5-Chlorovaleroyl chloride
2-amino-6-chlorobenzamide
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere; | 98% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 97% |
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 25 - 30℃; for 1h; Reagent/catalyst; | 97.84% |
Inert atmosphere; | |
Schotten-Baumann reaction; chemoselective reaction; | |
With triethylamine In tetrahydrofuran |
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane for 2h; Cooling with ice; | 97.8% |
Conditions | Yield |
---|---|
With hydrogenchloride; tin(IV) chloride In water; benzene | 97.7% |
Conditions | Yield |
---|---|
Stage #1: 5-Chlorovaleroyl chloride; aniline With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 0 - 5℃; for 1h; Stage #2: With potassium hydroxide In dichloromethane; water at 20℃; Reagent/catalyst; Temperature; Solvent; | 97.36% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 10 - 25℃; Inert atmosphere; | 97.3% |
5-Chlorovaleroyl chloride
Conditions | Yield |
---|---|
With potassium carbonate In water; acetone at -5 - 0℃; for 0.5h; Large scale; | 97.1% |
5-Chlorovaleroyl chloride
5-amino-N,N'-bis[2,3-bis(acetyloxy)propyl]2,4,6-triiodo-1,3-benzenedicarboxamide
N,N'-Bis[2,3-bis(Acetyloxy)propyl]-5-[(5-chloro-1-oxo-pentyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
Conditions | Yield |
---|---|
In N,N-dimethyl acetamide for 30h; Ambient temperature; | 97% |
5-Chlorovaleroyl chloride
5-amino-N,N'-bis[2,3-bis(acetyloxy)propyl]2,4,6-triiodo-1,3-benzenedicarboxamide
B
N,N'-Bis[2,3-bis(Acetyloxy)propyl]-5-[(5-chloro-1-oxo-pentyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
Conditions | Yield |
---|---|
In N,N-dimethyl acetamide; ethyl acetate | A 97% B n/a |
5-Chlorovaleroyl chloride
tert-butyl 1-(4-methoxyphenyl)hydrazine-1-carboxylate
Conditions | Yield |
---|---|
With sodium carbonate In dichloromethane; water at 0 - 20℃; | 97% |
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; | 97% |
5-Chlorovaleroyl chloride
1-(4-aminophenyl)-3-(morpholin-4-yl)-5,6-dihydropyridin-2(1H)-one
Conditions | Yield |
---|---|
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 0 - 5℃; for 1h; Reagent/catalyst; | 96.08% |
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 10 - 25℃; Inert atmosphere; | 89.5% |
With triethylamine In tetrahydrofuran at 5 - 50℃; for 2h; Inert atmosphere; |
5-Chlorovaleroyl chloride
1-methoxy-2-phenyl-1-(trimethylsiloxy)but-1-ene
Conditions | Yield |
---|---|
With 1-methyl-1H-imidazole; titanium tetrachloride In dichloromethane at 20 - 25℃; for 1.5h; Claisen condensation; | 96% |
With pentafluorophenylammonium triflate In dichloromethane at 60℃; for 1.5h; | 229 mg |
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