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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Coumaranone Manufacturer/High quality/Best price/In stock

Cas:553-86-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product description: Product name 2-Coumaranone CAS number 553-86-6 Assay ≥99% Appearance White or off-white crystal Capacity 1000mt/year Application Pesticide intermediate

2-Coumaranone

Cas:553-86-6

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (3H)-benzofuran-2-one

Cas:553-86-6

Min.Order:1

Negotiable

Type:Other

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EAST CHEMSOURCES LIMITED

Agrochemical Intermediate Appearance:White or yellowish - like crystals Storage:Store in a cool, dry, well ventilated warehouse. Package:25kg per bag Application:Agrochemical Intermediate Port:Any port of China

2-coumaranone

Cas:553-86-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% 2-COUMARANONE 553-86-6 GMP Manufacturer

Cas:553-86-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2(3H)-Benzofuranone

Cas:553-86-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2-COUMARANONE 553-86-6

Cas:553-86-6

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 553-86-6 with best quality

Cas:553-86-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

benzofuranone CAS553-86-6

Cas:553-86-6

Min.Order:1 Kilogram

FOB Price: $6.0 / 8.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

CAS Number 553-86-6 Product Name 2-Coumaranone Synonyms 1-benzofuran-2(3h)-one; 2(3h)-benzofuranone; 2,3-dihydrobenzo[b]furan-2-

2-Coumaranone CAS:553-86-6

Cas:553-86-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:off-white powder Storage:Store in sealed containers at cool

99% 2-Coumaranone 553-86-6 off-white powder

Cas:553-86-6

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Coumaranone 553-86-6

Cas:553-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply 2-COUMARANONE CAS 553-86-6

Cas:553-86-6

Min.Order:100 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-COUMARANONE CAS:553-86-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

2-COUMARANONE CAS:553-86-6

Cas:553-86-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Coumaranone

Cas:553-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Coumaranone

Cas:553-86-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 553-86-6 , 2-COUMARANONE

Cas:553-86-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Coumaranpne

Cas:553-86-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-COUMARANONE

Cas:553-86-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Coumaranone

Cas:553-86-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(3H)-benzofuran-2-on

Cas:553-86-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity Benzofuran-2(3H)-one

Cas:553-86-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Benzofuran-2(3H)-oneAppearance:white powder Storage:Keep away of light, cool place Package:according to customers' requirements Application:pharmaceutical intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or

Benzofuran-2(3H)-one

Cas:553-86-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-COUMARANONE

Cas:553-86-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:White or slightly yellowish, Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pest

2-Coumaranone

Cas:553-86-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-Coumaranone

Cas:553-86-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

2-COUMARANONE Basic information Description Reference Product Name: 2-COUMARANONE Synony

553-86-6 C8H6O2 2-COUMARANONE

Cas:553-86-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2-Coumaranone CAS No.:553-86-6 Molecule Formula:C8H6O2 Molecule Weight:134.13 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS SPECIFI

High Quality 2-Coumaranone in stock

Cas:553-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Coumaranone

Cas:553-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer2-Coumaranone

Cas:553-86-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-Hydroxyphenylacetic acid
614-75-5

2-Hydroxyphenylacetic acid

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With pyrophosphoryl chloride at 35℃; for 0.333333h;100%
With toluene-4-sulfonic acid In toluene for 4h; Heating;100%
With sulfuric acid In water; toluene at 100℃; for 6h; Reagent/catalyst; Temperature;98%
butyl o-acetoxyphenylacetate

butyl o-acetoxyphenylacetate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With tin(IV) oxide at 140℃; for 5h; Inert atmosphere;98%
2-[2-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-N,N-diethyl-acetamide

2-[2-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-N,N-diethyl-acetamide

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With trifluoroacetic acid In toluene for 1h; Heating;97%
potassium benzo[d][1,3]dioxol-5-yltrifluoroborate

potassium benzo[d][1,3]dioxol-5-yltrifluoroborate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With Oxone In water; acetone at 20℃; for 0.0333333h; Cooling with ice;97%
With Oxone; water In acetone at 20℃; for 0.0833333h;9%
With oxone In water; acetone for 2h;14 mg
ethyl o-acetoxyphenylacetate

ethyl o-acetoxyphenylacetate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With magnesium oxide at 120℃; for 2h; Temperature; Reagent/catalyst;97%
methyl o-acetoxyphenylacetate

methyl o-acetoxyphenylacetate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With alumina molecular sieve at 90℃; for 4h; Reagent/catalyst; Temperature; Inert atmosphere;96%
N,N-diethyl-2-(2-hydroxy)phenyl acetamide
182962-47-6

N,N-diethyl-2-(2-hydroxy)phenyl acetamide

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With hydrogenchloride In toluene for 40h; Heating;94%
With hydrogenchloride In water; benzene for 40h; Reagent/catalyst; Reflux;
2-benzofuranylboronic acid mida ester
1104637-65-1

2-benzofuranylboronic acid mida ester

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
Stage #1: 2-benzofuranylboronic acid mida ester With potassium hydrogen bifluoride In methanol; water at 70℃; for 2h;
Stage #2: With Oxone In methanol; water at 18℃; for 0.166667h;
89%
Multi-step reaction with 2 steps
1: methanol; water / 4 h / 70 °C
2: oxone / water; acetone / 2 h
View Scheme
allyl phenyl ether
1746-13-0

allyl phenyl ether

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
Stage #1: allyl phenyl ether With water; ozone at 15℃;
Stage #2: In water at 60℃;
85%
formic acid
64-18-6

formic acid

salicylic alcohol
90-01-7

salicylic alcohol

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); acetic anhydride; tris-(o-tolyl)phosphine In toluene at 30 - 100℃; for 3.5h; Catalytic behavior; Reagent/catalyst; Temperature; Inert atmosphere;84%
phenyl chloroacetate
620-73-5

phenyl chloroacetate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With aluminum (III) chloride In tetrachloromethane at 20℃; for 6h; Solvent; Reagent/catalyst; Temperature;83%
5-(tert-butyl)benzofuran-2(3H)-one
24431-30-9

5-(tert-butyl)benzofuran-2(3H)-one

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With aluminum (III) chloride In toluene Reflux;82.1%
phenoxyacetylene
4279-76-9

phenoxyacetylene

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With 2,6-lutidine N-oxide; tetrafluoroboric acid diethyl ether In 1,4-dioxane at 80℃; for 5h;81%
With 2,6-lutidine N-oxide; tetrafluoroboric acid diethyl ether In 1,4-dioxane at 80℃; for 3h;81%
phthalyl alcohol
612-14-6

phthalyl alcohol

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With [RuH(η2-BH4)(2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine)] In toluene at 115℃; for 48h; Inert atmosphere;76%
With phosphoric acid tributyl ester at 119.84℃; under 9375.94 Torr; for 8h; Catalytic behavior; Autoclave;48%
benzofuran-2-boronic acid
98437-24-2

benzofuran-2-boronic acid

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With N,N-dimethyl-p-toluidine N-oxide In dichloromethane at 20℃; for 2h;74%
methyl (2-hydroxyphenyl)acetate
22446-37-3

methyl (2-hydroxyphenyl)acetate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With aluminum (III) chloride; 2,6-di-tert-butyl-4-methyl-phenol; trifluoroacetic acid In 1,2-dichloro-benzene at 150℃; for 4h; Inert atmosphere; Sealed tube;70%
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
2.1: potassium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C / Inert atmosphere
2.2: 1 h / Inert atmosphere
3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: palladium on activated charcoal; hydrogen / ethanol / 20 °C / Inert atmosphere
5.1: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
2.1: potassium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C / Inert atmosphere
2.2: 1 h / Inert atmosphere
3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: palladium on activated charcoal; hydrogen / ethanol / 20 °C / Inert atmosphere
5.1: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
2.1: potassium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C / Inert atmosphere
2.2: 1 h / Inert atmosphere
3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: palladium on activated charcoal; hydrogen / ethanol / 20 °C / Inert atmosphere
5.1: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / 80 °C / Inert atmosphere
View Scheme
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With FeH6Mo6O24(3-)*3H3N*3H(1+)*7H2O; tetrabutylammomium bromide; dihydrogen peroxide In 1,4-dioxane at 70℃; for 24h;69%
3-hydroxy-2-pyrone
496-64-0

3-hydroxy-2-pyrone

methyl 3-nitrobut-3-enoate
34805-49-7

methyl 3-nitrobut-3-enoate

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With aluminum (III) chloride; 2,6-di-tert-butyl-4-methyl-phenol; trifluoroacetic acid In 1,2-dichloro-benzene at 120℃; for 20h; Reagent/catalyst; Temperature; Inert atmosphere; Sealed tube; regioselective reaction;64%
benzocyclobutenone
3469-06-5

benzocyclobutenone

A

2-benzofuran-1(3H)-one
87-41-2

2-benzofuran-1(3H)-one

B

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With Calcium tetrakis(pentafluorophenyl)borate; dihydrogen peroxide; oxalic acid In water; 1,2-dichloro-ethane at 50℃; for 6h; Reagent/catalyst;A 63%
B 24%
C20H26O8

C20H26O8

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
350255-13-9

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene at 80℃; Inert atmosphere;A n/a
B 63%
carbon monoxide
201230-82-2

carbon monoxide

salicylic alcohol
90-01-7

salicylic alcohol

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); benzoic acid In benzene at 125℃; under 3800 Torr; for 20h;59%
carbon monoxide
201230-82-2

carbon monoxide

salicylic alcohol
90-01-7

salicylic alcohol

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

ortho-cresol
95-48-7

ortho-cresol

C

2-Hydroxyphenylacetic acid
614-75-5

2-Hydroxyphenylacetic acid

Conditions
ConditionsYield
With hydrogen iodide; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane at 120℃; under 68400 Torr; for 42h; Carbonylation; reduction;A 9%
B 7%
C 56%
With tetrakis(triphenylphosphine) palladium(0); hydrogen iodide In 1,4-dioxane at 120℃; under 68400 Torr; for 42h;A 9 % Spectr.
B 7 % Spectr.
C 36%
C12H19N2O4P
133642-10-1

C12H19N2O4P

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With formic acid for 1h; Heating;54%
N,N-diethyl-2-methylcarbamoyloxybenzene
85630-35-9

N,N-diethyl-2-methylcarbamoyloxybenzene

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

N,N-diethyl-2-(2-hydroxy)phenyl acetamide
182962-47-6

N,N-diethyl-2-(2-hydroxy)phenyl acetamide

Conditions
ConditionsYield
With ammonium chloride; lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃;A 15%
B 54%
3-hydroxy-2-pyrone
496-64-0

3-hydroxy-2-pyrone

methyl 3-nitrobut-3-enoate
34805-49-7

methyl 3-nitrobut-3-enoate

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

methyl (2-hydroxyphenyl)acetate
22446-37-3

methyl (2-hydroxyphenyl)acetate

Conditions
ConditionsYield
With aluminum (III) chloride; 2,6-di-tert-butyl-4-methyl-phenol In 1,2-dichloro-benzene at 120℃; for 2h; Inert atmosphere;A 15%
B 53%
With 2,6-di-tert-butyl-4-methyl-phenol; dimethylaluminum chloride; trifluoroacetic acid In 1,2-dichloro-benzene at 100℃; for 2.5h; Inert atmosphere;A 30%
B 29%
2-diazo-1-phenylethan-1-one
21119-50-6

2-diazo-1-phenylethan-1-one

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane for 24h;43%
1H-benzo[4,5]furo[3,2-d]thiazol-2-ylideneamine
662109-78-6

1H-benzo[4,5]furo[3,2-d]thiazol-2-ylideneamine

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃;40%
4-Chlorophenoxyacetic acid
122-88-3

4-Chlorophenoxyacetic acid

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

5-chloro-2,3-dihydro-2-benzofuranone
28033-47-8

5-chloro-2,3-dihydro-2-benzofuranone

C

4-chloro-phenol
106-48-9

4-chloro-phenol

D

2-phenoxyacetic acid
122-59-8

2-phenoxyacetic acid

E

phenol
108-95-2

phenol

Conditions
ConditionsYield
With air In water for 7h; Product distribution; Ambient temperature; Irradiation; also under argon atmosphere; photodegradation pathways;A 7%
B 12%
C 28%
D 3%
E 38%
2-allylphenol
695-84-1

2-allylphenol

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

Conditions
ConditionsYield
With tert.-butylhydroperoxide; 2.9-dimethyl-1,10-phenanthroline; water; copper dichloride; palladium dichloride In nitromethane at 80℃; for 24h; chemoselective reaction;35%
1-benzofurane
271-89-6

1-benzofurane

A

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

B

2-hydroxy-3(2H)-benzofuranone
17392-15-3

2-hydroxy-3(2H)-benzofuranone

C

salicylaldehyde
90-02-8

salicylaldehyde

Conditions
ConditionsYield
With molybdenum peroxide hexamethylphosphorylamide In dichloromethane for 168h; Ambient temperature;A 7%
B 18%
C 12%
methanol
67-56-1

methanol

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

methyl (2-hydroxyphenyl)acetate
22446-37-3

methyl (2-hydroxyphenyl)acetate

Conditions
ConditionsYield
hydrogenchloride at 50℃; for 0.5h;99%
With amberlyst-15 for 26h;88%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

N-hydroxy-2-(2-hydroxyphenyl)acetamide
18639-02-6

N-hydroxy-2-(2-hydroxyphenyl)acetamide

Conditions
ConditionsYield
With hydroxylamine hydrochloride; potassium hydroxide In methanol at 0 - 20℃; Inert atmosphere;99%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

(2S,5S)-2,5-bis(methoxymethyl)pyrrolidine
90290-05-4, 93621-94-4, 105016-60-2, 144993-81-7

(2S,5S)-2,5-bis(methoxymethyl)pyrrolidine

1-[(2S,5S)-2,5-bis(methoxymethyl)pyrrolidin-1-yl]-2-(2-hydroxyphenyl)ethanone
1599446-48-6

1-[(2S,5S)-2,5-bis(methoxymethyl)pyrrolidin-1-yl]-2-(2-hydroxyphenyl)ethanone

Conditions
ConditionsYield
In toluene Reflux;99%
piperidine
110-89-4

piperidine

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2-(2-hydroxyphenyl)-1-(piperidin-1-yl)ethan-1-one
24789-88-6

2-(2-hydroxyphenyl)-1-(piperidin-1-yl)ethan-1-one

Conditions
ConditionsYield
In toluene at 110℃;98%
With toluene-4-sulfonic acid In toluene at 110℃;98%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

salicylaldehyde
90-02-8

salicylaldehyde

3-(2-hydroxyphenyl)-2H-chromen-2-one
13130-21-7

3-(2-hydroxyphenyl)-2H-chromen-2-one

Conditions
ConditionsYield
With triethylamine for 1h; Reflux;98%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Reagent/catalyst; Sealed tube;97%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

C16H14ClNO
1486473-80-6

C16H14ClNO

(3S*,11b'S*)-3'-chloro-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a]quinolin]-2-one

(3S*,11b'S*)-3'-chloro-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a]quinolin]-2-one

Conditions
ConditionsYield
With piperidine In N,N-dimethyl acetamide at 150℃; for 4h; Inert atmosphere; diastereoselective reaction;98%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)benzaldehyde
124525-62-8

2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)benzaldehyde

(3S*,11b'S*)-9',10'-dimethoxy-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a]quinolin]-2-one

(3S*,11b'S*)-9',10'-dimethoxy-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a]quinolin]-2-one

Conditions
ConditionsYield
With piperidine In N,N-dimethyl acetamide at 150℃; for 5h; Inert atmosphere; diastereoselective reaction;98%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

C15H13BrN2O

C15H13BrN2O

(3S*,11b'S*)-2'-bromo-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a][1,8]naphthyridin]-2-one

(3S*,11b'S*)-2'-bromo-6',7',11b',13'-tetrahydro-2H-spiro[benzofuran-3,12'-isoquinolino[2,1-a][1,8]naphthyridin]-2-one

Conditions
ConditionsYield
With piperidine In N,N-dimethyl acetamide at 150℃; for 7h; Inert atmosphere; diastereoselective reaction;98%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

buta-2,3-dienoic acid benzyl ester
187661-86-5

buta-2,3-dienoic acid benzyl ester

benzyl (E)-4-(3-(4-(benzyloxy)-4-oxobut-1-en-2-yl)-2-oxo-2,3-dihydrobenzofuran-3-yl)but-2-enoate

benzyl (E)-4-(3-(4-(benzyloxy)-4-oxobut-1-en-2-yl)-2-oxo-2,3-dihydrobenzofuran-3-yl)but-2-enoate

Conditions
ConditionsYield
With triphenylphosphine In toluene at 20℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;97%
2-hydroxy-5-methoxybenzaldehyde
672-13-9

2-hydroxy-5-methoxybenzaldehyde

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

3-(2-hydroxyphenyl)-6-methoxy-2H-chromen-2-one

3-(2-hydroxyphenyl)-6-methoxy-2H-chromen-2-one

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
With triethylamine for 1h; Reflux;96%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2-hydroxy-5-methylbenzaldehyde
613-84-3

2-hydroxy-5-methylbenzaldehyde

3-(2-hydroxyphenyl)-6-methyl-2H-chromen-2-one
1338596-79-4

3-(2-hydroxyphenyl)-6-methyl-2H-chromen-2-one

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
With triethylamine for 1h; Reflux;90%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2-fluoro-6-hydroxybenzaldehyde
38226-10-7

2-fluoro-6-hydroxybenzaldehyde

5-fluoro-3-(2-hydroxyphenyl)coumarin

5-fluoro-3-(2-hydroxyphenyl)coumarin

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;97%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

trimethyl orthoformate
149-73-5

trimethyl orthoformate

3-(α-methoxy)methylene benzofuran-2-(3H)-ketone
40800-90-6

3-(α-methoxy)methylene benzofuran-2-(3H)-ketone

Conditions
ConditionsYield
With acetic anhydride at 95 - 100℃; Concentration;96.5%
With acetic anhydride at 40 - 90℃; Temperature;96.8%
at 110℃; for 21h; Large scale;
With zinc(II) chloride at 110℃; for 4h;
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

2-(2-hydroxyphenyl)ethanol
7768-28-7

2-(2-hydroxyphenyl)ethanol

Conditions
ConditionsYield
With methanol; Na/SiO2 In tetrahydrofuran at 0 - 25℃; Bouveault-Blanc reduction; Inert atmosphere;96%
With lithium aluminium tetrahydride In diethyl ether Heating;
With sodium tetrahydroborate In tetrahydrofuran at 0 - 30℃; for 5h; Reagent/catalyst; Solvent; Temperature;9.1 g
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

diethylamine
109-89-7

diethylamine

N,N-diethyl-2-(2-hydroxy)phenyl acetamide
182962-47-6

N,N-diethyl-2-(2-hydroxy)phenyl acetamide

Conditions
ConditionsYield
In toluene at 110℃;96%
With toluene-4-sulfonic acid In toluene at 110℃;96%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

ethylenediamine
107-15-3

ethylenediamine

N,N'-(ethane-1,2-diyl)bis(2-(2-hydroxyphenyl)acetamide)

N,N'-(ethane-1,2-diyl)bis(2-(2-hydroxyphenyl)acetamide)

Conditions
ConditionsYield
In ethanol at 20℃; Inert atmosphere;95%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

2-(2-hydroxyphenyl)-N-(1S-α-phenylethyl)acetamide
543681-05-6

2-(2-hydroxyphenyl)-N-(1S-α-phenylethyl)acetamide

Conditions
ConditionsYield
In toluene at 20℃; for 0.0833333h;95%
In toluene Heating;
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

1,5-bis(4-trifluoromethylphenyl)-1,4-pentadiene-3-one
103836-71-1, 103836-73-3, 103836-74-4, 42160-07-6

1,5-bis(4-trifluoromethylphenyl)-1,4-pentadiene-3-one

C27H18F6O3

C27H18F6O3

Conditions
ConditionsYield
With QD-4 In para-xylene at 20℃; for 96h; Catalytic behavior; Michael Addition; stereoselective reaction;95%
2-Hydroxy-4-methoxybenzaldehyde
673-22-3

2-Hydroxy-4-methoxybenzaldehyde

benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

3-(2-hydroxyphenyl)-7-methoxy-2H-chromen-2-one

3-(2-hydroxyphenyl)-7-methoxy-2H-chromen-2-one

Conditions
ConditionsYield
With triethylamine for 1h; Reflux;95%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;95%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;95%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

5-Nitrosalicylaldehyde
97-51-8

5-Nitrosalicylaldehyde

3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one
13130-30-8

3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one

Conditions
ConditionsYield
With triethylamine for 1h; Reflux;95%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

4-fluoro-2-hydroxybenzaldehyde
348-28-7

4-fluoro-2-hydroxybenzaldehyde

7-fluoro-3-(2-hydroxyphenyl)coumarin

7-fluoro-3-(2-hydroxyphenyl)coumarin

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;95%
With N,N,N',N'-tetramethylguanidine In chloroform at 20℃; for 3h; Sealed tube;95%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

carbon monoxide
201230-82-2

carbon monoxide

3-hydroxymethylenebenzofuran-2(3H)-one
70450-82-7

3-hydroxymethylenebenzofuran-2(3H)-one

Conditions
ConditionsYield
With sodium methylate In N,N-dimethyl-formamide at 40℃; under 225023 Torr; for 6h; Reagent/catalyst; Solvent; Temperature; Pressure; Green chemistry;95%
benzofuran-2(3H)-one
553-86-6

benzofuran-2(3H)-one

(Dimethylamino)ethoxyacetaldehyd-dimethylhydrazon
99412-47-2

(Dimethylamino)ethoxyacetaldehyd-dimethylhydrazon

3-<2-(Dimethylhydrazono)ethyliden>-2(3H)-benzofuranon

3-<2-(Dimethylhydrazono)ethyliden>-2(3H)-benzofuranon

Conditions
ConditionsYield
In ethanol Ambient temperature;94%

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