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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-p-xylene

Cas:553-94-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2,5-Dimethylbromobenzene 553-94-6

Cas:553-94-6

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2,5-Dimethylbromobenzene_

Cas:553-94-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 553-94-6 with best quality

Cas:553-94-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzene,2-bromo-1,4-dimethyl-

Cas:553-94-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzene,2-bromo-1,4-dimethyl-

Cas:553-94-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzene,2-bromo-1,4-dimethyl-

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:clear colorless to light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Intermed

2-Bromo-p-xylene

Cas:553-94-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Bromo-p-xylene

Cas:553-94-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Minstar Chemical Co., Ltd

2,5-Dimethylbromobenzene Chemical Properties Melting point 9-10 °C(lit.) Boiling point 199-201 °C(lit.) density 1.34 g/mL at 25 °C(lit.) refractive index n20/D 1.550(lit.) Fp 175 °F form Liquid color Clear

2-Bromo-1,4-dimethylbenzene

Cas:553-94-6

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

2-Bromo-1,4-dimethylbenzene

Cas:553-94-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-BROMO-P-XYLENE

Cas:553-94-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2,5-Dimethylbromobenzene

Cas:553-94-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

2,5-Dimethylbromobenzene Manufacturer/High quality/Best price/In stock CAS NO.553-94-6

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Benzene,2-bromo-1,4-dimethyl-

Cas:553-94-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

1,4-Dimethyl-2-bromobenzene cas no. 553-94-6 98%

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Bromo-1,4-dimethylbenzen

Cas:553-94-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Bromo-p-xylene

Cas:553-94-6

Min.Order:0

Negotiable

Type:Other

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

2,5-Dimethylbromobenzene CAS 553-94-6

Cas:553-94-6

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

para-xylene
106-42-3

para-xylene

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With potassium bromide; sodium nitrite In water; trifluoroacetic acid at 20℃; for 0.16h; Product distribution; under argon;100%
With oxygen; potassium bromide; sodium nitrite In water; trifluoroacetic acid at 20℃; for 5h; Product distribution;96%
With sulfuric acid; dihydrogen peroxide; sodium bromide In water at 49.84℃;94%
para-xylene
106-42-3

para-xylene

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

2,5-dibromo-p-xylene
1074-24-4

2,5-dibromo-p-xylene

Conditions
ConditionsYield
With carbon dioxide; bromine at 40℃; under 187519 Torr; for 2h; Supercritical conditions; Green chemistry;A 92%
B 8%
With aluminum oxide; bromine for 0.0166667h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With N-Bromosuccinimide at 20℃; for 16h; Overall yield = 85 %Spectr.; regioselective reaction;
para-xylene
106-42-3

para-xylene

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

2,5-dibromo-p-xylene
1074-24-4

2,5-dibromo-p-xylene

C

4-Methylbenzyl bromide
104-81-4

4-Methylbenzyl bromide

Conditions
ConditionsYield
With bromine; acetic acidA 77%
B 10%
C 13%
With bromineA 48%
B n/a
C n/a
para-xylene
106-42-3

para-xylene

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

4-Methylbenzyl bromide
104-81-4

4-Methylbenzyl bromide

Conditions
ConditionsYield
With sodium bromate; sodium hydrogensulfite In water; acetonitrile at 20℃; for 4h; Bromination;A 62%
B n/a
With bromine; bentonite In carbon disulfide for 4h; Heating;A 50%
B 30%
With N-Bromosuccinimide In methanol at 150℃; under 2625.26 Torr; for 0.0666667h; microwave irradiation;A 27 % Chromat.
B 32 % Chromat.
With hydrogen bromide; dihydrogen peroxide In water at 20℃; for 24h; Darkness;A 66 %Spectr.
B 14 %Spectr.
With N-Bromosuccinimide; silver hexafluoroantimonate; adamantan-1-yl(methyl)sulfane In 1,2-dichloro-ethane at 20℃; for 1h; Inert atmosphere; Schlenk technique;A 50 %Chromat.
B 20 %Chromat.
1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dimethylbenzene
356570-53-1

1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dimethylbenzene

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With copper(ll) bromide In methanol Heating;46%
2,5-Dimethylaniline
95-78-3

2,5-Dimethylaniline

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With hydrogen bromide diazotization;40%
(i) (diazotization), aq. HBr, (ii) Cu; Multistep reaction;
Methyl fluoride
593-53-3

Methyl fluoride

2-methylphenyl bromide
95-46-5

2-methylphenyl bromide

A

2-Bromo-m-xylene
576-22-7

2-Bromo-m-xylene

B

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

C

1-bromo-2,4-dimethylbenzene
583-70-0

1-bromo-2,4-dimethylbenzene

D

2,3-dimethylbromobenzene
576-23-8

2,3-dimethylbromobenzene

Conditions
ConditionsYield
With oxygen at 40℃; under 720 Torr; Mechanism; Irradiation;A n/a
B n/a
C 13.7%
D 32.8%
2,5-dimethylbenzenesulfonic acid
609-54-1

2,5-dimethylbenzenesulfonic acid

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With copper(ll) bromide
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

(E)-1,4-Dimethyl-1,3-hexadien-5-in-1-yl-triflat
93362-61-9

(E)-1,4-Dimethyl-1,3-hexadien-5-in-1-yl-triflat

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

(4-Methylbenzyl)-(2,2,2-trifluorethyl)-ether
79644-39-6

(4-Methylbenzyl)-(2,2,2-trifluorethyl)-ether

C

(Z)-3-Methyl-hept-3-ene-1,5-diyne
79644-36-3

(Z)-3-Methyl-hept-3-ene-1,5-diyne

D

(2,5-Dimethylphenyl)-(2,2,2-trifluorethyl)-ether
79644-38-5

(2,5-Dimethylphenyl)-(2,2,2-trifluorethyl)-ether

Conditions
ConditionsYield
With 1,3,5-triisopropyl benzene; sodium carbonate; lithium bromide In 1,4-dioxane; water at 120℃; for 120h; Mechanism; Product distribution;A 17 % Chromat.
B 14 % Chromat.
C n/a
D 14 % Chromat.
para-xylene
106-42-3

para-xylene

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

2,6-dibromo-1,4-dimethylbenzene
66788-13-4

2,6-dibromo-1,4-dimethylbenzene

Conditions
ConditionsYield
With aluminum oxide; copper(ll) bromide In tetrachloromethane at 80℃; for 1.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
para-xylene
106-42-3

para-xylene

A

4-Methylbenzyl alcohol
589-18-4

4-Methylbenzyl alcohol

B

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

C

1,4-dimethyl-2-(4-methylbenzyl)benzene
721-45-9

1,4-dimethyl-2-(4-methylbenzyl)benzene

D

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

Conditions
ConditionsYield
With sulfuric acid; hydrogen bromide In water; acetic acid at 90℃; for 1h; Product distribution; Mechanism; other solvent, effect of the absence of HBr;A 65 % Chromat.
B 30 % Chromat.
C 71 % Chromat.
D 22 % Chromat.
3-methylbicyclo<4.1.0>hepta-1,3,5-triene
75366-05-1

3-methylbicyclo<4.1.0>hepta-1,3,5-triene

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

1-bromo-2,4-dimethylbenzene
583-70-0

1-bromo-2,4-dimethylbenzene

Conditions
ConditionsYield
With bromine; tri-n-butyl-tin hydride Product distribution; Mechanism; multistep reaction; reaction regioselectivity; a series of reagents;
(E)-1,4-Dimethyl-1,3-hexadien-5-in-1-yl-triflat
93362-61-9

(E)-1,4-Dimethyl-1,3-hexadien-5-in-1-yl-triflat

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

(4-Methylbenzyl)-(2,2,2-trifluorethyl)-ether
79644-39-6

(4-Methylbenzyl)-(2,2,2-trifluorethyl)-ether

C

(2,5-Dimethylphenyl)-(2,2,2-trifluorethyl)-ether
79644-38-5

(2,5-Dimethylphenyl)-(2,2,2-trifluorethyl)-ether

D

2,5-dimethylphenyl trifluoromethanesulfonate
79644-40-9

2,5-dimethylphenyl trifluoromethanesulfonate

Conditions
ConditionsYield
With 2,2,2-trifluoroethanol; sodium carbonate; lithium bromide In 1,4-dioxane; water at 100℃; for 120h; Further byproducts given;A 16.6 % Chromat.
B 41.2 % Chromat.
C 14.4 % Chromat.
D 1 % Chromat.
para-xylene
106-42-3

para-xylene

iodine
7553-56-2

iodine

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
beim Bromieren;
para-xylene
106-42-3

para-xylene

iodine
7553-56-2

iodine

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

2,5-dibromo-p-xylene
1074-24-4

2,5-dibromo-p-xylene

Conditions
ConditionsYield
beim Bromieren;
para-xylene
106-42-3

para-xylene

iodine
7553-56-2

iodine

A

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

B

2,5-dibromo-p-xylene
1074-24-4

2,5-dibromo-p-xylene

C

2,3,5,6-tetrabromo-p-xylene
23488-38-2

2,3,5,6-tetrabromo-p-xylene

Conditions
ConditionsYield
beim Bromieren;
diazotized 2-amino-p-xylene

diazotized 2-amino-p-xylene

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With hydrogen bromide; copper(I) bromide
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

platinum

platinum

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 93 percent / pyridine / CH2Cl2 / 0.25 h / 0 °C
2: 99 percent / Et3N / PdCl2(dppf) / dioxane / Heating
3: 46 percent / aq. CuBr2 / methanol / Heating
View Scheme
2,5-dimethylphenyl trifluoromethanesulfonate
79644-40-9

2,5-dimethylphenyl trifluoromethanesulfonate

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / Et3N / PdCl2(dppf) / dioxane / Heating
2: 46 percent / aq. CuBr2 / methanol / Heating
View Scheme
2,3-dibromo-1,4-dimethylbenzene
15540-84-8

2,3-dibromo-1,4-dimethylbenzene

A

para-xylene
106-42-3

para-xylene

B

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

Conditions
ConditionsYield
With tris(2,2'-bipyridine)ruthenium(II) perchlorate; triethanolamine; Ni((C6H5)CH2O)(C5H2N)(CH2)2(NHCH2CH2CH2)2NH(2+) In acetonitrile at 25℃; for 3h; Photolysis;
With nickel(II) 1,4,8,11-tetraazacyclotetradecane; tris(2,2'-bipyridine)ruthenium(II) perchlorate; triethanolamine In acetonitrile at 25℃; for 3h; Photolysis;
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

triethyl phosphite
122-52-1

triethyl phosphite

(2,5-dimethylphenyl)diethyl phosphonate
58983-18-9

(2,5-dimethylphenyl)diethyl phosphonate

Conditions
ConditionsYield
With nickel dibromide at 160℃; for 2h; Inert atmosphere;100%
Irradiation;
2-tert-Butylphenol
88-18-6

2-tert-Butylphenol

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

3-tert-butyl-2',5'-dimethylbiphenyl-2-ol

3-tert-butyl-2',5'-dimethylbiphenyl-2-ol

Conditions
ConditionsYield
With tris(triphenylphosphine)rhodium(I) chloride; caesium carbonate; diisopropyl(2-tert-butyl)phenoxyphosphine In toluene for 18h; Heating;100%
With caesium carbonate; diisopropyl(2-tert-butyl)phenoxyphosphine; RhCl(PPh3)3 In toluene for 18h; Heating;100%
With caesium carbonate; chloro(1,5-cyclooctadiene)rhodium(I) dimer In toluene for 18h; Heating;94 % Spectr.
triisopropyl phosphite
116-17-6

triisopropyl phosphite

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

(2,5-dimethylphenyl)diisopropyl phosphonate

(2,5-dimethylphenyl)diisopropyl phosphonate

Conditions
ConditionsYield
With nickel dibromide at 150℃; for 3h; Inert atmosphere;100%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

4-bromo-1-(3'-chloro-1'-oxopropyl)-2,5-dimethylbenzene
246022-83-3

4-bromo-1-(3'-chloro-1'-oxopropyl)-2,5-dimethylbenzene

Conditions
ConditionsYield
Stage #1: 2-chloropropionyl chloride With aluminum (III) chloride In dichloromethane for 0.25h; Schlenk technique; Inert atmosphere;
Stage #2: 4-bromo-m-xylene In dichloromethane at 20℃; for 20h; Inert atmosphere;
99%
With aluminium trichloride In dichloromethane at 50℃; for 3h; Addition;87%
With aluminum (III) chloride In carbon disulfide at 0℃; for 1h; Reflux;61%
With aluminium trichloride In carbon disulfide at 20℃; for 16h;
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

2,5,2'-trimethyl-1,1'-biphenyl
76708-72-0

2,5,2'-trimethyl-1,1'-biphenyl

Conditions
ConditionsYield
With Merrifield resin-bound dicyclohexylphosphinobiphenyl ligand; caesium carbonate; tris(dibenzylideneacetone)dipalladium (0) In tetrahydrofuran at 65℃; Suzuki reaction;99%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

1-amino-3-methylbenzene
108-44-1

1-amino-3-methylbenzene

N-(2,5-dimethylphenyl)-m-toluidine

N-(2,5-dimethylphenyl)-m-toluidine

Conditions
ConditionsYield
With Merrifield resin-bound dicyclohexylphosphinobiphenyl ligand; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃;99%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-phenylaniline
90-41-5

2-phenylaniline

2,5-dimethyl-2'-phenyldiphenylamine

2,5-dimethyl-2'-phenyldiphenylamine

Conditions
ConditionsYield
With palladium diacetate; P(i-BuNCH2CH2)3N; sodium t-butanolate In toluene at 80℃;99%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-(2,5-dimethylphenyl)acetyl chloride
55312-97-5

2-(2,5-dimethylphenyl)acetyl chloride

Conditions
ConditionsYield
Stage #1: 4-bromo-m-xylene; chloroacetyl chloride With hydrogenchloride; ruthenium(IV) oxide; palladium 10% on activated carbon In dimethyl sulfoxide at 100℃; for 5h;
Stage #2: With sodium sulfite In water; dimethyl sulfoxide at 135℃; for 8.25h; Temperature;
98.1%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

1-(2,5-dimethylhenyl)-4-methylpiperazine

1-(2,5-dimethylhenyl)-4-methylpiperazine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 80℃; for 4h;98%
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate at 80℃; for 4h; Arylation;98%
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In neat (no solvent) at 80℃; for 4h; Inert atmosphere;98%
With tris(dibenzylideneacetone)dipalladium (0); sodium isopropylate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 110℃; for 7h; Substitution;68%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

p-toluidine
106-49-0

p-toluidine

N-(4-methylphenyl)-2,5-dimethylaniline
34160-15-1

N-(4-methylphenyl)-2,5-dimethylaniline

Conditions
ConditionsYield
With bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate; palladium dichloride In toluene at 80℃; for 17h;98%
With palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate In toluene at 80℃; for 3h;95%
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 110℃; for 4h; Inert atmosphere;67%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

bis(2,5-dimethylphenyl) sulfide
35019-02-4

bis(2,5-dimethylphenyl) sulfide

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; thiourea; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In 1,4-dioxane at 100℃; for 18h; Inert atmosphere;98%
lithium trimethoxy(1,2,2-trifluorovinyl)borate

lithium trimethoxy(1,2,2-trifluorovinyl)borate

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

1,4-dimethyl-2-(1,2,2-trifluorovinyl)benzene
1361925-73-6

1,4-dimethyl-2-(1,2,2-trifluorovinyl)benzene

Conditions
ConditionsYield
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); XPhos In tetrahydrofuran at 20 - 80℃; for 15.25h; Suzuki coupling; Inert atmosphere;98%
2-bromoacetyl chloride
22118-09-8

2-bromoacetyl chloride

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-(2,5-dimethylphenyl)acetyl chloride
55312-97-5

2-(2,5-dimethylphenyl)acetyl chloride

Conditions
ConditionsYield
Stage #1: 2-bromoacetyl chloride; 4-bromo-m-xylene With hydrogenchloride; ruthenium(IV) oxide; palladium 10% on activated carbon In dimethyl sulfoxide at 100℃; for 5h;
Stage #2: With sodium sulfite In water; dimethyl sulfoxide at 135℃; for 8.25h;
97.1%
dimethylmonochlorosilane
1066-35-9

dimethylmonochlorosilane

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

(2,5-dimethylphenyl)dimethylsilane

(2,5-dimethylphenyl)dimethylsilane

Conditions
ConditionsYield
Stage #1: 4-bromo-m-xylene With n-butyllithium In tetrahydrofuran at -78℃; for 3h; Inert atmosphere;
Stage #2: dimethylmonochlorosilane In tetrahydrofuran at -78 - 20℃;
97%
With tert.-butyl lithium In diethyl ether; pentane 1.) -78 deg C, 2.) -78 deg C to 20 deg C, 2 h; Yield given;
morpholine
110-91-8

morpholine

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

4-(2,5-dimethylphenyl)morpholine

4-(2,5-dimethylphenyl)morpholine

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); (-)-2-(dicyclohexylphosphino)-2'-(dimethylamino)-1,1'-binaphthyl; sodium t-butanolate In 1,2-dimethoxyethane Ambient temperature;97%
With potassium hexamethylsilazane In 1,4-dioxane at 100℃; for 0.25h; metal-free Buchwald-Hartwig amination; Inert atmosphere;88 %Chromat.
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-methoxy-phenylamine
90-04-0

2-methoxy-phenylamine

N-(2-methoxyphenyl)-2,5-dimethylaniline

N-(2-methoxyphenyl)-2,5-dimethylaniline

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); sodium isopropylate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 110℃; for 19h; Substitution;97%
With bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate; palladium dichloride In toluene at 80℃; for 4h;93%
With palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate In toluene at 80℃; for 21h;90%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

trans-2-phenylvinylboronic acid
6783-05-7

trans-2-phenylvinylboronic acid

(E)-2,5-dimethyl-1-styrylbenzene
19290-86-9, 21162-42-5

(E)-2,5-dimethyl-1-styrylbenzene

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate In tetrahydrofuran at 40℃; for 24h; Suzuki-Miyaura coupling;97%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

1-Naphthylboronic acid
13922-41-3

1-Naphthylboronic acid

1-(2,5-dimethylphenyl)naphthalene
131117-61-8

1-(2,5-dimethylphenyl)naphthalene

Conditions
ConditionsYield
With potassium phosphate; C29H37O2P; palladium diacetate In toluene at 110℃; for 3h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;97%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

ortho-cresol
95-48-7

ortho-cresol

1,4-dimethyl-2-(o-tolyloxy)benzene

1,4-dimethyl-2-(o-tolyloxy)benzene

Conditions
ConditionsYield
With palladium diacetate; potassium phosphate; 2-N,N-(dimethylamino)-2'-di-tert-butylphosphino-1,1'-binaphthyl In toluene at 100℃; for 24h;96%
With potassium phosphate; tert-butyl XPhos; palladium diacetate In toluene at 100℃; for 24h;92%
With potassium phosphate; 2-di-tert-butylphosphino-2',4',6'-tricyclohexyl-3,6-dimethoxybiphenyl In 1,2-dimethoxyethane; toluene at 40℃; for 24h; Inert atmosphere;80%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

N-methylaniline
100-61-8

N-methylaniline

N-methyl-N-phenyl-2,5-dimethylbenzenamine

N-methyl-N-phenyl-2,5-dimethylbenzenamine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate at 80℃; for 36h; Arylation;95%
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 80℃; for 36h;94%
With tris(dibenzylideneacetone)dipalladium (0); sodium isopropylate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 110℃; for 22h; Substitution;85%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

4’-chloro-2,5-dimethyl-1,1’-biphenyl
71149-93-4

4’-chloro-2,5-dimethyl-1,1’-biphenyl

Conditions
ConditionsYield
With potassium phosphate; monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0) In toluene at 100℃; for 14h; Suzuki coupling;95%
With potassium phosphate; monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0) In toluene95%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

bicyclo[2.2.1]hepta-2,5-diene
121-46-0

bicyclo[2.2.1]hepta-2,5-diene

C23H24

C23H24

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; triphenylphosphine In toluene at 20 - 115℃; for 5h; Temperature; Reagent/catalyst; Solvent; Sealed tube; stereoselective reaction;95%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 3-(2,5-dimethylphenyl)prop-2-enoate

methyl 3-(2,5-dimethylphenyl)prop-2-enoate

Conditions
ConditionsYield
With N-Methyldicyclohexylamine; 2C32H41O4P*Pd(2+)*2Cl(1-) In N,N-dimethyl acetamide at 100℃; for 16h; Heck Reaction; Inert atmosphere;95%
oxirane
75-21-8

oxirane

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

2-(2,5-dimethylphenyl)ethan-1-ol
6972-51-6

2-(2,5-dimethylphenyl)ethan-1-ol

Conditions
ConditionsYield
Stage #1: 4-bromo-m-xylene With iodine; magnesium In diethyl ether at 60℃; for 1h; Inert atmosphere;
Stage #2: oxirane In diethyl ether at 0℃; for 3h; Temperature; Inert atmosphere;
94.69%
(i) Mg, Et2O, (ii) /BRN= 102378/; Multistep reaction;
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

phenylboronic acid
98-80-6

phenylboronic acid

2,5-dimethylbiphenyl
7372-85-2

2,5-dimethylbiphenyl

Conditions
ConditionsYield
With palladium diacetate; potassium fluoride; johnphos In tetrahydrofuran at 45℃; for 12h; Suzuki coupling;94%
With potassium phosphate; Pd (sulfur-containing palladacycle); tetra(n-tert-butyl)ammonium bromide In N,N-dimethyl-formamide at 25℃; for 38h; Suzuki cross-coupling;94%
With Pd(4,4'-bis(diphenylphosphino)-2,2',6,6'-tetra-methoxy-3,3'-bipyridine)Cl2; potassium hydroxide In ethanol; dichloromethane at 25℃; for 6h; Suzuki-Miyaura Coupling;94%
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

phenylacetylene
536-74-3

phenylacetylene

1,4-dimethyl-2-(phenylethynyl)benzene
29778-30-1

1,4-dimethyl-2-(phenylethynyl)benzene

Conditions
ConditionsYield
With potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine In 1,4-dioxane at 105℃; for 20h; Sonogashira coupling; Inert atmosphere;94%
With dichloro[1-(2,4,6-trimethylbenzyl)-3-(4-adamantylbenzyl)-5,6-dimethylbenzimidazole-2-ylidene]triphenylphosphine palladium(II); potassium tert-butylate In N,N-dimethyl-formamide at 100℃; for 3h; Reagent/catalyst; Sonogashira Cross-Coupling; Schlenk technique;94%
With potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); tetraphosphine N,N,N′,N′-tetra(diphenylphosphinomethyl)-pyridine-2,6-diamine In N,N-dimethyl acetamide; water at 100℃; for 20h; Sonogashira Cross-Coupling; Schlenk technique; Inert atmosphere;93%
2,6-bis-(toluene-4-sulfonyl)-[1,5,2,6]dithiadiazocane
23516-76-9

2,6-bis-(toluene-4-sulfonyl)-[1,5,2,6]dithiadiazocane

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

C17H21NO2S2

C17H21NO2S2

Conditions
ConditionsYield
Stage #1: 4-bromo-m-xylene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6-bis-(toluene-4-sulfonyl)-[1,5,2,6]dithiadiazocane In tetrahydrofuran for 0.5h; Inert atmosphere;
94%
pyrrolidine
123-75-1

pyrrolidine

4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

N-(2,5-xylyl)pyrrolidine
97053-04-8

N-(2,5-xylyl)pyrrolidine

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In 1,4-dioxane at 100℃; for 17h; Arylation;93%
With pyridine; bis(1,5-cyclooctadiene)nickel (0); 1,10-Phenanthroline; sodium t-butanolate at 100℃; Glovebox; Inert atmosphere;8 %Chromat.
4-bromo-m-xylene
553-94-6

4-bromo-m-xylene

1-amino-2-propene
107-11-9

1-amino-2-propene

N-allyl-2,5-xylidine
13519-81-8

N-allyl-2,5-xylidine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); johnphos; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 80℃; for 6h; Arylation;93%

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