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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (2R,3S)-3-Phenylisoserine Hydrochloride supplier in China

Cas:132201-32-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name ((2R,3S)-3-Phenylisoserine hydrochloride CAS number 132201-32-2 Assay ≥99% Appearance White powder Capacity 100mt/year Application Pharmace

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of (2R,3S)-3-Phenylisoserine hydrochloride Cas 132201-32-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:Cool dry place Package

High quality (2R,3S)-3-Phenylisoserine hydrochloride Cas 132201-32-2 with best price

Cas:132201-32-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Our advantage: 1: High quality and Competitive price 2: Quality control, GC&HPLC&NMR or as your requested 3: Packing as your requested, and double check before shipment 4: Prompt shipment with professional documents 5: Excellent after-

(2R,3S)-3-Phenylisoserine Hydrochloride CAS NO.132201-32-2

Cas:132201-32-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

product name: (2R,3S)-3-Phenylisoserine hydrochloride Synonyms: (2R,3S)-3-Amino-2-hydroxy-3-phenyl-propanoic acid hydrochloride;(2r,3s)-3-phenylisoserine hydrochloride;(2R,3S)-3-PHENYLISOSERINE HCl;(2R,3S)-3-phenylisoserine.HCl;(2R,3S)

132201-32-2 (2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 132201-32-2 with best quality

Cas:132201-32-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

(2R,3S)-3-Phenylisoserine hydrochloride/ LIDE PHARMA- Factory supply / Best price

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(2R,3S)-3-Phenylisoserine hydrochloride 132201-32-2

Cas:132201-32-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

132201-32-2 (2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

(2R,3S)-PHENYLISOSERINE HYDROCHLORIDE

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(2R,3S)-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

stocks High quality Low price Appearance:White Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:API Transportation:shipping,land,air Port:Shanghai

(2R,3S)-Phenylisoserine Hydrochloride;132201-32-2

Cas:132201-32-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name:(2R,3S)-3-Phenylisoserine Hydrochloride CAS No.:132201-32-2 Molecule Formula:C9H12ClNO3 Molecule Weight:217.65 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard

Best Quality (2R,3S)-3-Phenylisoserine Hydrochloride

Cas:132201-32-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(2R,3S)-3-Phenylisoserinehydrochloride

Cas:132201-32-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(2R,3S)-3-Phenylisoserine HCl

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ (2R,3S)-Phenylisoserine Hydrochloride /Manufacturer in China

Cas:132201-32-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. is a leading company that is focused on developing and producing high-quality flavor ingredients used for foods, pharmaceutic, cosmetics, and daily-use goods. Our goal is to produce flavor ingredients through scien

2R,3S)-3-Phenylisoserine hydrochloride manufacture

Cas:132201-32-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

highest purity most favorable priceAppearance:solid or liquid Storage:room temperature under 25℃ Package:drum or bag Application:for pharmaceutical Transportation:by sea and air

;(2r,3s)-3-phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

(2R,3S)-3-Phenylisoserine Hydrochloride

Cas:132201-32-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(2R,3S)-3-Phenylisoserine hydrochloride

Cas:132201-32-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

(3R,4S)-3-hydroxy-4-phenylazetidin-2-one
132127-34-5

(3R,4S)-3-hydroxy-4-phenylazetidin-2-one

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 12h; Heating;100%
With hydrogenchloride at 25℃; for 3h;
3-Triisopropylsilyloxy-4-phenylazetidin-2-one
132127-31-2, 132201-31-1

3-Triisopropylsilyloxy-4-phenylazetidin-2-one

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 25℃; for 3h;100%
Multi-step reaction with 2 steps
1: 81 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.42 h / Ambient temperature
2: 6N hydrochloric acid / 3 h / 25 °C
View Scheme
(2R,3S)-3-Amino-2-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-propionic acid isopropyl ester
201339-42-6

(2R,3S)-3-Amino-2-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-propionic acid isopropyl ester

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride Heating;100%
(3R,4S)-3-triisopropylsilyloxy-4-phenylazetidin-2-one
132127-31-2

(3R,4S)-3-triisopropylsilyloxy-4-phenylazetidin-2-one

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 25℃; for 5h;98%
Multi-step reaction with 2 steps
1: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature
2: 100 percent / 6 N HCl / 12 h / Heating
View Scheme
C16H19NO5

C16H19NO5

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water for 5h; Reflux;95%
methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate
122743-18-4

methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Stage #1: methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate With sulfuric acid; acetonitrile at -10 - 20℃;
Stage #2: With hydrogenchloride Heating;
86%
Multi-step reaction with 5 steps
1: p-TsOH / CH2Cl2 / 5 h / Ambient temperature
2: AcBr / CH2Cl2 / 2 h / -15 °C
3: NaN3 / dimethylformamide / 50 °C
4: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
5: 10percent aq. HCl / 2 h / Heating
View Scheme
Methyl N-acetyl-3-phenylisoserine
158225-44-6

Methyl N-acetyl-3-phenylisoserine

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 2h; Heating;
(2R,3S)-3-acetylamino-2-hydroxy-3-phenylpropanoic acid isopropyl ester
195624-97-6

(2R,3S)-3-acetylamino-2-hydroxy-3-phenylpropanoic acid isopropyl ester

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 4h; Yield given;
With hydrogenchloride In water for 4h; Heating;
(2R,3S)-2,3-dihydroxy-3-phenyl-propionic acid
56816-81-0

(2R,3S)-2,3-dihydroxy-3-phenyl-propionic acid

A

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

B

(2R,3R)-3-carboxy-2-hydroxy-1-phenylpropanylammonium hydrochloride

(2R,3R)-3-carboxy-2-hydroxy-1-phenylpropanylammonium hydrochloride

Conditions
ConditionsYield
Stage #1: (2R,3S)-2,3-dihydroxy-3-phenyl-propionic acid With sulfuric acid; acetonitrile at -10 - 20℃; for 2h;
Stage #2: With hydrogenchloride for 2h; Heating;
(E)-isopropyl cinnamate
60512-85-8

(E)-isopropyl cinnamate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 81 percent / K2OsO2(OH)4; (DHQ)2-PHAL; LiOH
2: HCl / H2O / 4 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 81 percent / (DHQ)2PHAL, aq. LiOH, K22(OH)4> / 2-methyl-propan-2-ol / 20 h / 4 °C
2: 10percent aq. HCl / 4 h / 100 °C
View Scheme
(E)-N-benzylidene-2-hydroxyaniline
3230-45-3

(E)-N-benzylidene-2-hydroxyaniline

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: (S)-6,6'-dibromo-1,1'-bi-2-naphthol-1,2-dimethylimidazole - Zr(IV) complex / toluene / -78 °C
2: K2CO3
3: cerium ammonium nitrate / methanol
4: 100 percent / 10percent aq. HCl / Heating
View Scheme
Multi-step reaction with 4 steps
1: (R)-6,6'-dibromo-1,1'-bi-2-naphthol-1,2-dimethylimidazole - Zr(IV) complex / toluene / 20 h / -78 °C
2: K2CO3
3: cerium ammonium nitrate / methanol
4: 100 percent / 10percent aq. HCl / Heating
View Scheme
(2R,3S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-(2-methoxy-phenylamino)-3-phenyl-propionic acid isopropyl ester
201339-46-0

(2R,3S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-(2-methoxy-phenylamino)-3-phenyl-propionic acid isopropyl ester

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: cerium ammonium nitrate / methanol
2: 100 percent / 10percent aq. HCl / Heating
View Scheme
isopropyl 2-tert-butyldimethylsiloxy-3-(2-hydroxyphenyl)amino-3-phenylpropionate
201339-41-5

isopropyl 2-tert-butyldimethylsiloxy-3-(2-hydroxyphenyl)amino-3-phenylpropionate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: cerium ammonium nitrate / methanol
3: 100 percent / 10percent aq. HCl / Heating
View Scheme
Methyl cinnamate
103-26-4

Methyl cinnamate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 71 percent / (DHQ)2PHAL, NMO, K2OsO2(OH)4 / H2O; 2-methyl-propan-2-ol / 23 h / Ambient temperature
2: p-TsOH / CH2Cl2 / 5 h / Ambient temperature
3: AcBr / CH2Cl2 / 2 h / -15 °C
4: NaN3 / dimethylformamide / 50 °C
5: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
6: 10percent aq. HCl / 2 h / Heating
View Scheme
methyl 2-acetoxy-3-azido-3-phenylpropanoate
158341-43-6

methyl 2-acetoxy-3-azido-3-phenylpropanoate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
2: 10percent aq. HCl / 2 h / Heating
View Scheme
methyl (2R,3S)-2-acetoxy-3-bromo-3-phenylpropionate
145987-13-9

methyl (2R,3S)-2-acetoxy-3-bromo-3-phenylpropionate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaN3 / dimethylformamide / 50 °C
2: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
3: 10percent aq. HCl / 2 h / Heating
View Scheme
(4R,5S)-2-Methoxy-2-methyl-5-phenyl-[1,3]dioxolane-4-carboxylic acid methyl ester
186758-09-8

(4R,5S)-2-Methoxy-2-methyl-5-phenyl-[1,3]dioxolane-4-carboxylic acid methyl ester

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: AcBr / CH2Cl2 / 2 h / -15 °C
2: NaN3 / dimethylformamide / 50 °C
3: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
4: 10percent aq. HCl / 2 h / Heating
View Scheme
N-benzylidene-1,1,1-trimethylsilanamine
17599-61-0

N-benzylidene-1,1,1-trimethylsilanamine

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
2: 81 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.42 h / Ambient temperature
3: 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
2: 100 percent / 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 3 steps
1: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
2: 81 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.42 h / Ambient temperature
3: 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
2: 100 percent / 6N hydrochloric acid / 3 h / 25 °C
View Scheme
benzaldehyde
100-52-7

benzaldehyde

aminoguanidine salt

aminoguanidine salt

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1. hexamethyldisilazane, n-BuLi / 1. THF, hexane, reflux, 3 h; 2. reflux, 2 h
2: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
3: 81 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.42 h / Ambient temperature
4: 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 3 steps
1: 1. hexamethyldisilazane, n-BuLi / 1. THF, hexane, reflux, 3 h; 2. reflux, 2 h
2: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
3: 100 percent / 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 4 steps
1: 1. hexamethyldisilazane, n-BuLi / 1. THF, hexane, reflux, 3 h; 2. reflux, 2 h
2: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
3: 81 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.42 h / Ambient temperature
4: 6N hydrochloric acid / 3 h / 25 °C
View Scheme
Multi-step reaction with 3 steps
1: 1. hexamethyldisilazane, n-BuLi / 1. THF, hexane, reflux, 3 h; 2. reflux, 2 h
2: 1. diisopropylamine, n-butyllithium / 1. THF, 2 h; 2. THF a.) -78 deg C, 4 h, b.) r.t.
3: 100 percent / 6N hydrochloric acid / 3 h / 25 °C
View Scheme
[4-(benzylideneamino)phenyl]methanol
783-08-4

[4-(benzylideneamino)phenyl]methanol

1400

1400

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) LDA / 2.) THF, -95 deg C to -78 deg C
2: cerium ammonium nitrate / tetrahydrofuran
3: 98 percent / 6N hydrochloric acid / 5 h / 25 °C
View Scheme
1-(4-Methoxyphenyl)-3-triisopropylsilyloxy-4-phenyl-2-azetidinone
144465-78-1

1-(4-Methoxyphenyl)-3-triisopropylsilyloxy-4-phenyl-2-azetidinone

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: cerium ammonium nitrate / tetrahydrofuran
2: 98 percent / 6N hydrochloric acid / 5 h / 25 °C
View Scheme
(E)-N-benzylidene-1,1,1-trimethylsilanamine
120419-97-8

(E)-N-benzylidene-1,1,1-trimethylsilanamine

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) LDA / 2a) THF, -78 deg C, 4 h, 2b) rt, overnight
2: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature
3: 100 percent / 6 N HCl / 12 h / Heating
View Scheme
(2R,3S)-3-amino-2-hydroxy-3-phenylpropionic acid ethyl ester
143615-00-3

(2R,3S)-3-amino-2-hydroxy-3-phenylpropionic acid ethyl ester

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water Heating;
C12H13NO4

C12H13NO4

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Burkholderia cepacia lipase / di-isopropyl ether / 0.08 h / 50 °C / Resolution of racemate; Enzymatic reaction
2: hydrogenchloride; water / 5 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: Burkholderia cepacia lipase / toluene / 0.08 h / 50 °C / Resolution of racemate; Enzymatic reaction
2: hydrogenchloride; water / 5 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: Burkholderia cepacia lipase / di-isopropyl ether / 0.5 h / 25 °C / Enzymatic reaction
2: hydrogenchloride; water / 5 h / Reflux
View Scheme
cis-rac-3-acetoxy-4-phenylazetidin-2-one

cis-rac-3-acetoxy-4-phenylazetidin-2-one

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Sonication
2: Burkholderia cepacia lipase / di-isopropyl ether / 0.08 h / 50 °C / Resolution of racemate; Enzymatic reaction
3: hydrogenchloride; water / 5 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: Sonication
2: Burkholderia cepacia lipase / toluene / 0.08 h / 50 °C / Resolution of racemate; Enzymatic reaction
3: hydrogenchloride; water / 5 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: Sonication
2: Burkholderia cepacia lipase / di-isopropyl ether / 0.5 h / 25 °C / Enzymatic reaction
3: hydrogenchloride; water / 5 h / Reflux
View Scheme
3-Phenylpropenol
104-54-1

3-Phenylpropenol

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: D-(-)-diisopropyl tartrate; titanium(IV)isopropoxide / dichloromethane / Molecular sieve
2: sulfuric acid / 8 h / 20 - 25 °C
3: dipyridine chromium(VI) oxide / dichloromethane / 10 °C
4: hydrogenchloride / water / 100 - 110 °C
View Scheme
(2S,3S)-2,3-epoxy-3-phenyl-1-propanol
104196-23-8

(2S,3S)-2,3-epoxy-3-phenyl-1-propanol

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sulfuric acid / 8 h / 20 - 25 °C
2: dipyridine chromium(VI) oxide / dichloromethane / 10 °C
3: hydrogenchloride / water / 100 - 110 °C
View Scheme
C11H11NO3

C11H11NO3

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water at 100 - 110℃;
methanol
67-56-1

methanol

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

methyl (2R,3S)-3-phenylisoserinate hydrochloride

methyl (2R,3S)-3-phenylisoserinate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0℃; for 3h;100%
With thionyl chloride at 0℃;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

RPR 130523
145514-62-1

RPR 130523

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetone89%
With triethylamine In tetrahydrofuran; water at 0 - 20℃;
With sodium hydroxide In tetrahydrofuran
methanol
67-56-1

methanol

benzoyl chloride
98-88-4

benzoyl chloride

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate
32981-85-4

methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: benzoyl chloride; (2R,3S)-3-phenylisoserine hydrochloride With sodium hydroxide In water at 20℃; for 1h; pH=9 - 12;
Stage #2: methanol Concentration;
85.6%
benzoyl chloride
98-88-4

benzoyl chloride

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(2R,3S)-N-benzoyl-3-phenylisoserine
132201-33-3

(2R,3S)-N-benzoyl-3-phenylisoserine

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane; water for 16h; Ambient temperature;72%
With sodium hydrogencarbonate In dichloromethane; water70%
With sodium hydroxide for 3h; Ambient temperature; Yield given;
methanol
67-56-1

methanol

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate
124605-42-1

methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate

Conditions
ConditionsYield
Stage #1: di-tert-butyl dicarbonate; (2R,3S)-3-phenylisoserine hydrochloride With sodium hydroxide In tetrahydrofuran; water at 20 - 40℃; for 4h;
Stage #2: methanol
60%
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

orthobenzoic acid trimethyl ester
707-07-3

orthobenzoic acid trimethyl ester

(4S,5R)-2,4-diphenyl-2-oxazoline-5-carboxylic acid methyl ester
146848-91-1

(4S,5R)-2,4-diphenyl-2-oxazoline-5-carboxylic acid methyl ester

Conditions
ConditionsYield
In toluene for 8h; Heating;41%
toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

benzyl alcohol
100-51-6

benzyl alcohol

(2R,3S)-3-Amino-2-hydroxy-3-phenyl-propionic acid benzyl ester; compound with toluene-4-sulfonic acid

(2R,3S)-3-Amino-2-hydroxy-3-phenyl-propionic acid benzyl ester; compound with toluene-4-sulfonic acid

Conditions
ConditionsYield
In benzene for 10h; Heating;1600 mg
succinimidyl 2,2,2-trichloroethyl carbonate
66065-85-8

succinimidyl 2,2,2-trichloroethyl carbonate

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(2R,3S)-2-Hydroxy-3-phenyl-3-(2,2,2-trichloro-ethoxycarbonylamino)-propionic acid

(2R,3S)-2-Hydroxy-3-phenyl-3-(2,2,2-trichloro-ethoxycarbonylamino)-propionic acid

Conditions
ConditionsYield
With sodium hydroxide; sodium hydrogencarbonate In 1,4-dioxane at 20℃; for 1h;
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

(2R,3S)-3-Benzyloxycarbonylamino-2-hydroxy-3-phenyl-propionic acid

(2R,3S)-3-Benzyloxycarbonylamino-2-hydroxy-3-phenyl-propionic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In diethyl ether at 0 - 20℃;
With sodium hydroxide In 1,4-dioxane at 0℃; for 3h;
methanol
67-56-1

methanol

(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(2R,3S)-3-phenylisoserine methyl ester
157240-36-3

(2R,3S)-3-phenylisoserine methyl ester

Conditions
ConditionsYield
With thionyl chloride at 20℃;
With thionyl chloride at 20℃; for 6h; Time; Cooling with ice;
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(4S,5R)-2-(4-Methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-benzyl ester

(4S,5R)-2-(4-Methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: SOCl2 / 20 °C
2: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4: aq. KOH / methanol / 2 h / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(4S,5R)-5-methoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-3-benzyloxycarbonyl-1,3-oxazolidine

(4S,5R)-5-methoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-3-benzyloxycarbonyl-1,3-oxazolidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: SOCl2 / 20 °C
2: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

2'-O-tert-butoxycarbonyl-3'-N-de(tert-butoxycarbonyl)docetaxel

2'-O-tert-butoxycarbonyl-3'-N-de(tert-butoxycarbonyl)docetaxel

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: SOCl2 / 20 °C
2.1: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3.1: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4.1: aq. KOH / methanol / 2 h / 20 °C
5.1: DMAP; DCC / CH2Cl2 / 2 h / 20 °C
5.2: 80 percent / p-toluenesulfonic acid / methanol / 5 h / 20 °C
6.1: 84 percent / pyridine; DMAP / CH2Cl2 / 20 °C
7.1: H2 / Pd/C / ethyl acetate / 8 h / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

13-(3'-N-benzyloxycarbonylphenylisoserine)-10-deacetyl-7,10-dibenzyloxycarbonylbaccatin III
850933-54-9

13-(3'-N-benzyloxycarbonylphenylisoserine)-10-deacetyl-7,10-dibenzyloxycarbonylbaccatin III

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: SOCl2 / 20 °C
2.1: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3.1: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4.1: aq. KOH / methanol / 2 h / 20 °C
5.1: DMAP; DCC / CH2Cl2 / 2 h / 20 °C
5.2: 80 percent / p-toluenesulfonic acid / methanol / 5 h / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

13-(3'-N-benzyloxycarbonyl-2'-tert-butoxycarbonylphenylisoserine)-10-deacetyl-7,10-dibenzyloxycarbonylbaccatin III
850933-55-0

13-(3'-N-benzyloxycarbonyl-2'-tert-butoxycarbonylphenylisoserine)-10-deacetyl-7,10-dibenzyloxycarbonylbaccatin III

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: SOCl2 / 20 °C
2.1: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3.1: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4.1: aq. KOH / methanol / 2 h / 20 °C
5.1: DMAP; DCC / CH2Cl2 / 2 h / 20 °C
5.2: 80 percent / p-toluenesulfonic acid / methanol / 5 h / 20 °C
6.1: 84 percent / pyridine; DMAP / CH2Cl2 / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

C70H69NO19

C70H69NO19

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: SOCl2 / 20 °C
2.1: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3.1: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4.1: aq. KOH / methanol / 2 h / 20 °C
5.1: DMAP; DCC / CH2Cl2 / 2 h / 20 °C
5.2: p-toluenesulfonic acid / methanol / 5 h / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
133524-69-3, 133577-36-3, 133577-37-4

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: SOCl2 / 20 °C
2.1: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
3.1: 469 mg / pyridinium p-toluenesulfonate / toluene / Heating
4.1: aq. KOH / methanol / 2 h / 20 °C
5.1: DMAP; DCC / CH2Cl2 / 2 h / 20 °C
5.2: 80 percent / p-toluenesulfonic acid / methanol / 5 h / 20 °C
6.1: H2 / Pd/C / ethyl acetate / 8 h / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(-)-(2R,3S)-methyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate
158810-74-3

(-)-(2R,3S)-methyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: SOCl2 / 20 °C
2: aq. NaHCO3 / CH2Cl2 / 3 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 100 percent / SOCl2 / 0 °C
2: NaHCO3
View Scheme
Multi-step reaction with 2 steps
1: 100 percent / SOCl2 / 3 h / 0 °C
2: 86 percent / NaHCO3 / CH2Cl2 / 2 h
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide / 1,4-dioxane / 3 h / 0 °C
2: N,N-dimethyl-formamide; thionyl chloride / 12 h / -78 - 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid
158722-22-6

(4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / H2O
View Scheme
Multi-step reaction with 2 steps
1: 41 percent / toluene / 8 h / Heating
2: 86 percent / NaOH / methanol; H2O / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(4S,5R)-2,4-Diphenyl-4,5-dihydro-oxazole-5-carboxylic acid (4S,4aR)-6,6,8-trimethyl-4,4a,5,6,7,9-hexahydro-2-oxa-cyclopenta[f]azulen-4-yl ester
395664-53-6

(4S,5R)-2,4-Diphenyl-4,5-dihydro-oxazole-5-carboxylic acid (4S,4aR)-6,6,8-trimethyl-4,4a,5,6,7,9-hexahydro-2-oxa-cyclopenta[f]azulen-4-yl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOH / H2O
2: DCC; DMAP / CH2Cl2 / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 41 percent / toluene / 8 h / Heating
2: 86 percent / NaOH / methanol; H2O / 20 °C
3: dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 20 °C
View Scheme
(2R,3S)-3-phenylisoserine hydrochloride
132201-32-2

(2R,3S)-3-phenylisoserine hydrochloride

(4S,5R)-2,4-Diphenyl-4,5-dihydro-oxazole-5-carboxylic acid (1aS,3aS,6aS,6bR)-1a-formyl-5,5,6b-trimethyl-1,1a,3a,4,5,6,6a,6b-octahydro-cyclopropa[e]inden-2-ylmethyl ester
395664-47-8

(4S,5R)-2,4-Diphenyl-4,5-dihydro-oxazole-5-carboxylic acid (1aS,3aS,6aS,6bR)-1a-formyl-5,5,6b-trimethyl-1,1a,3a,4,5,6,6a,6b-octahydro-cyclopropa[e]inden-2-ylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOH / H2O
2: DCC; DMAP / CH2Cl2 / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 41 percent / toluene / 8 h / Heating
2: 86 percent / NaOH / methanol; H2O / 20 °C
3: dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 20 °C
View Scheme

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