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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N,N,N'-trimethylethylenediamine

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Item Quality Standard Test Result Appearance colorless clear liquid colorless clear liquid Assay %

high purity 142-25-6 N,N,N'-Trimethyl ethylenediamine

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $1.9 / 2.5

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

N,N,N'-Trimethylethylenediamine CAS No.:142-25-6 Name: N,N,N'-Trimethylethylenediamine Molecular Structure Molecular Formula: C5H14N2 Molecular Weight: 102.18 CAS Registry Number: 142-25-

High purity N,N,N'-Trimethylethylenediamine CAS No.:142-25-6

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 142-25-6 N,N,N'-TRIMETHYLETHYLENEDIAMINE Manufacturer

Cas:142-25-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

N,N,N'-Trimethylethylenediamine

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N,N,N'-Trimethylethylenediamine

Cas:142-25-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship

142-25-6 2-(Dimethylamino)-N-methylethylamine

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

High Purity 99% N, N, N′ -Trimethylethylenediamine CAS 142-25-6 with Realiable Price

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 142-25-6 with best quality

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

2-(Dimethylamino)-N-methylethylamine 98% CAS 142-25-6

Cas:142-25-6

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,2-Ethanediamine,N1,N1,N2-trimethyl- 142-25-6

Cas:142-25-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

142-25-6 N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

N,N,N'-TRIMETHYLETHYLENEDIAMINE CAS: 142-25-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

N,N,N'-TRIMETHYLETHYLENEDIAMINE CAS: 142-25-6

Cas:142-25-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,2-Ethanediamine,N1,N1,N2-trimethyl-

Cas:142-25-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

N,N,N′-trimethylethylenediamine cas:142-25-6

Cas:142-25-6

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

N. N, N '- trimethylethylenediamine CAS: 142-25-6 Specification Prodcut name N,N,N'-TRIMETHYLETHYLENEDIAMINE Synonyms dimethyl(2-(methylamino)ethyl)amine 2-(Dimethylamino)-N-methylethylamine 1,2-Diaminoeth

Factory supply N. N, N '- trimethylethylenediamine

Cas:142-25-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,2-Ethanediamine,N1,N1,N2-trimethyl-

Cas:142-25-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

N,N,N’-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,2-Ethanediamine,N1,N1,N2-trimethyl-

Cas:142-25-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products N,N,N'-TRIMETHYLETHYLENEDIAMINE(142-25-6)

Cas:142-25-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

N,N,N'-Trimethylethylenediamine

Cas:142-25-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

142-25-6 N,N,N'-TRIMETHYLETHYLENEDIAMINE

Cas:142-25-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply N,N,N'-Trimethyl ethylenediamine

Cas:142-25-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

High Purity 99% N, N, N′ -Trimethylethylenediamine CAS 142-25-6

Cas:142-25-6

Min.Order:1 Kilogram

FOB Price: $88.0 / 98.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: N,N,N’-Trimethylethylenediamine CAS No.: 142-25-6 Molecule Formula:C5H16N2 Molecule Weight:104.19 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard

Lower Price N,N,N’-Trimethylethylenediamine on stock

Cas:142-25-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

methylamine
74-89-5

methylamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
In water for 1h; Ambient temperature;97%
With sodium hydroxide at 25℃;80%
In water for 6h; Heating;60%
4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine
383865-57-4

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine

A

1-(2-Dimethylamino-ethyl)-3-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-1-methyl-urea

1-(2-Dimethylamino-ethyl)-3-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-1-methyl-urea

B

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
A 61%
B n/a
3-(N,N-dimethylamino)propylamide
20101-88-6

3-(N,N-dimethylamino)propylamide

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
N,N,N'-trimethyl-N'-phenyl-ethylenediamine
79049-82-4

N,N,N'-trimethyl-N'-phenyl-ethylenediamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
nitrosieren,mit alkalisch machen und Kochen mit NaHSO3-Loesung;
N-methyl-2-chloroethylamine
32315-92-7

N-methyl-2-chloroethylamine

dimethyl amine
124-40-3

dimethyl amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

methylamine
74-89-5

methylamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
With water
at 115 - 120℃;
2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

methylamine
74-89-5

methylamine

A

N,N,N',N'',N'''-pentamethyldiethylenetriamine
3030-47-5

N,N,N',N'',N'''-pentamethyldiethylenetriamine

B

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
With water
2-[(2-Dimethylamino-ethyl)-methyl-amino]-2-hydroxy-1-phenyl-ethanone

2-[(2-Dimethylamino-ethyl)-methyl-amino]-2-hydroxy-1-phenyl-ethanone

A

2,2-dihydroxy-1-phenyl-ethanone
1075-06-5

2,2-dihydroxy-1-phenyl-ethanone

B

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
In water at 35℃; Equilibrium constant;
Dimethyl-β-formylaminoethylamine
7249-51-6

Dimethyl-β-formylaminoethylamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride
(CdI2(N,N,N`-trimethylethylenediamine)
114320-99-9

(CdI2(N,N,N`-trimethylethylenediamine)

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

cadmium(II) iodide

cadmium(II) iodide

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 135-300 ° C;
(HgI2(N,N,N`-trimethylethylenediamine)
114321-02-7

(HgI2(N,N,N`-trimethylethylenediamine)

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

mercury(II) iodide

mercury(II) iodide

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 95-180 ° C;
(CdCl2(N,N,N`-trimethylenediamine)2

(CdCl2(N,N,N`-trimethylenediamine)2

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

cadmium(II) chloride
10108-64-2

cadmium(II) chloride

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 150-350 ° C;
(CdBr2(N,N,N`-trimethylethylenediamine)2

(CdBr2(N,N,N`-trimethylethylenediamine)2

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

cadmium(II) bromide

cadmium(II) bromide

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 140-290 ° C;
(HgCl2(N,N,N`-trimethylethylenediamine)3

(HgCl2(N,N,N`-trimethylethylenediamine)3

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

mercury dichloride

mercury dichloride

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 120-170 ° C;
(HgBr2(N,N,N`-trimethylethylenediamine)3

(HgBr2(N,N,N`-trimethylethylenediamine)3

A

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

B

mercury dibromide

mercury dibromide

Conditions
ConditionsYield
In neat (no solvent) thermal decompn. by loss of ligand followed by vaporization of metal halide, temp. range 115-175 ° C;
methanol
67-56-1

methanol

Reaxys ID: 11370757

Reaxys ID: 11370757

ethylenediamine
107-15-3

ethylenediamine

A

N,N,N,N,-tetramethylethylenediamine
110-18-9

N,N,N,N,-tetramethylethylenediamine

B

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

C

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

D

N-methyl-ethane-1,2-diamine
109-81-9

N-methyl-ethane-1,2-diamine

E

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
ConditionsYield
Stage #1: With hydrogen at 200℃; for 3h;
Stage #2: methanol; ethylenediamine With hydrogen at 200℃; under 7500.75 Torr; for 8h; Product distribution / selectivity;
ethylenediamine
107-15-3

ethylenediamine

dimethyl sulfate
77-78-1

dimethyl sulfate

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

Conditions
ConditionsYield
In ethanol Cooling with ice;
N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

N,N,N'-trimethyl-N'-(2-nitrophenyl)-1,2-ethanediamine
371244-16-5

N,N,N'-trimethyl-N'-(2-nitrophenyl)-1,2-ethanediamine

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol at 80℃; for 16h;100%
2-bromo-6-nitro-benzo[d]thiazole
2516-37-2

2-bromo-6-nitro-benzo[d]thiazole

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N,N,N'-trimethyl-N'-(6-nitro-benzothiazol-2-yl)-ethane-1,2-diamine
892840-64-1

N,N,N'-trimethyl-N'-(6-nitro-benzothiazol-2-yl)-ethane-1,2-diamine

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 6h;100%
N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

β-11-O-desacetyl-11-O-propionyl-17-dihydrowortmannin
174304-96-2

β-11-O-desacetyl-11-O-propionyl-17-dihydrowortmannin

propionic acid 4-{[(2-dimethylamino-ethyl)-methyl-amino]-methylene}-6,17-dihydroxy-1-methoxymethyl-10,13-dimethyl-3,7-dioxo-1,3,4,7,10,11,12,13,14,15,16,17-dodecahydro-2-oxa-cyclopenta[a]phenanthren-11-yl ester

propionic acid 4-{[(2-dimethylamino-ethyl)-methyl-amino]-methylene}-6,17-dihydroxy-1-methoxymethyl-10,13-dimethyl-3,7-dioxo-1,3,4,7,10,11,12,13,14,15,16,17-dodecahydro-2-oxa-cyclopenta[a]phenanthren-11-yl ester

Conditions
ConditionsYield
In dichloromethane at 20℃;100%
3-acetylbenzene-1-sulfonyl chloride
73035-16-2

3-acetylbenzene-1-sulfonyl chloride

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

3-acetyl-N-[2-(dimethylamino)ethyl]-N-methylbenzenesulfonamide
1186422-04-7

3-acetyl-N-[2-(dimethylamino)ethyl]-N-methylbenzenesulfonamide

Conditions
ConditionsYield
In tetrahydrofuran for 18h;100%
Pentafluoropyridine
700-16-3

Pentafluoropyridine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

C10H13F4N3
1193367-04-2

C10H13F4N3

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; regioselective reaction;100%
Decyl-oxiran
2855-19-8

Decyl-oxiran

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

2,5-dimethyl-7-hydroxy-2,5-diazaheptadecane
1233939-61-1

2,5-dimethyl-7-hydroxy-2,5-diazaheptadecane

Conditions
ConditionsYield
In ethanol at 20℃; for 120h;100%
N- (4-fluoro-2-methoxy-5-nitrophenyl)-4-(1H-indol-3-yl)pyrimidin-2-amine
1421372-34-0

N- (4-fluoro-2-methoxy-5-nitrophenyl)-4-(1H-indol-3-yl)pyrimidin-2-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(4-(1H-indol-3-yl)pyrimidin-2-yl)-N4-(2-(dimethylamino)ethyl)-2-methoxy-N4-methyl-5-nitrobenzene-1,4-diamine
1421373-32-1

N1-(4-(1H-indol-3-yl)pyrimidin-2-yl)-N4-(2-(dimethylamino)ethyl)-2-methoxy-N4-methyl-5-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 120℃; for 0.5h; Microwave irradiation; Inert atmosphere;100%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 140℃; for 0.5h; Microwave irradiation;80%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 140℃; for 0.5h; Inert atmosphere; Microwave irradiation;80%
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 140℃; for 1h;73.1%
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 140℃; for 2.5h;0.36 g
N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1,N1,N2-trimethyl-N2-[2-(phenylsulfonyl)ethyl]-1,2-ethanediamine
1496553-60-6

N1,N1,N2-trimethyl-N2-[2-(phenylsulfonyl)ethyl]-1,2-ethanediamine

Conditions
ConditionsYield
In dichloromethane at 20℃;100%
methyl 2-amino-4-bromo-6-fluoro-3-nitro-benzoate
1160683-38-4

methyl 2-amino-4-bromo-6-fluoro-3-nitro-benzoate

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

methyl 2-amino-4-bromo-6-[(2-dimethylaminoethyl)methylamino]-3-nitrobenzoate

methyl 2-amino-4-bromo-6-[(2-dimethylaminoethyl)methylamino]-3-nitrobenzoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at -45℃; for 2h; Inert atmosphere;100%
4-fluoro-2-methoxy-5-nitro-phenylamine
1075705-01-9

4-fluoro-2-methoxy-5-nitro-phenylamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-2-nitro-1,4-phenylenediamine

N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-2-nitro-1,4-phenylenediamine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 48h; Inert atmosphere;100%
With potassium carbonate In acetonitrile at 85℃; for 12h;79.2%
With potassium carbonate In acetonitrile at 80℃; Inert atmosphere;62.5%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
6-(3-(dimethylamino)phenyl)-N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

6-(3-(dimethylamino)phenyl)-N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(3-(dimethylamino)phenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(3-(dimethylamino)phenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
6-(4-(dimethylamino)phenyl)-N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

6-(4-(dimethylamino)phenyl)-N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(4-(dimethylamino)phenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(4-(dimethylamino)phenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N3-(4-fluoro-2-methoxy-5-nitrophenyl)-N6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1Hindazole-3,6-diamine

N3-(4-fluoro-2-methoxy-5-nitrophenyl)-N6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1Hindazole-3,6-diamine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N3-(4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)-N6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-3,6-diamine

N3-(4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)-N6-(3-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-3,6-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(5-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(5-(naphthalen-2-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(5-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(5-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-5-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(5-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(5-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;100%
(2-((5-fluoro-2-((4-fluoro-2-methoxy-5-nitrophenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

(2-((5-fluoro-2-((4-fluoro-2-methoxy-5-nitrophenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

(2-((2-((4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)amino)-5-fluoropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

(2-((2-((4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)amino)-5-fluoropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

Conditions
ConditionsYield
In 1,4-dioxane at 100℃; for 2h;100%
N-(6-chloro-2-isopropyloxy-5-nitropyridin-3-yl)acetamide

N-(6-chloro-2-isopropyloxy-5-nitropyridin-3-yl)acetamide

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N-{6-{[2-(dimethylamino)ethyl](methyl)amino}-2-isopropyloxy-5-nitropyridin-3-yl}acetamide

N-{6-{[2-(dimethylamino)ethyl](methyl)amino}-2-isopropyloxy-5-nitropyridin-3-yl}acetamide

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃;100%
3-fluoro-4-nitrobenzoic acid
403-21-4

3-fluoro-4-nitrobenzoic acid

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

3-((2-(dimethylamino)ethyl)(methyl)amino)-4-nitrobenzoic acid

3-((2-(dimethylamino)ethyl)(methyl)amino)-4-nitrobenzoic acid

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;100%
With caesium carbonate In acetonitrile at 20℃; for 10h;
2-chloro-4-fluorobenzaldehyde
84194-36-5

2-chloro-4-fluorobenzaldehyde

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

2-chloro-4-{[2-(dimethylamino)ethyl](methyl)amino}benzaldehyde

2-chloro-4-{[2-(dimethylamino)ethyl](methyl)amino}benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 5.25h;100%
2-Amino-6-bromopyridine
19798-81-3

2-Amino-6-bromopyridine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N2-(2-(dimethylamino)ethyl)-N2-methylpyridine-2,6-diamine

N2-(2-(dimethylamino)ethyl)-N2-methylpyridine-2,6-diamine

Conditions
ConditionsYield
With caesium carbonate In 1-methyl-pyrrolidin-2-one at 200℃; for 0.333333h; Microwave irradiation;100%
N-(4-fluoro-2-methoxy-5-nitro-phenyl)acetamide

N-(4-fluoro-2-methoxy-5-nitro-phenyl)acetamide

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

C14H22N4O4

C14H22N4O4

Conditions
ConditionsYield
With sodium carbonate In ethanol at 80℃; for 1.5h; Inert atmosphere;99.87%
(4-fluoro-2-methoxy-5-nitrophenyl)carbamic acid tert-butyl ester

(4-fluoro-2-methoxy-5-nitrophenyl)carbamic acid tert-butyl ester

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N-(t-butoxycarbonyl)-4-((N,1-(2-(N,N-dimethylamino)ethyl)-N,1-methyl)amino)-2-methoxy-5-nitroanilide

N-(t-butoxycarbonyl)-4-((N,1-(2-(N,N-dimethylamino)ethyl)-N,1-methyl)amino)-2-methoxy-5-nitroanilide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20 - 60℃; for 2h;99%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 45℃; for 2h; Inert atmosphere;98%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 60℃; for 2h;92%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-2-nitro-N4-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)benzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-2-nitro-N4-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)benzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;99%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(naphthalen-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;99%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(isoquinolin-4-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(isoquinolin-4-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(isoquinolin-4-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-N4-(6-(isoquinolin-4-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-5-methoxy-N1-methyl-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;99%
N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(1-methyl-1H-indol-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N-(4-fluoro-2-methoxy-5-nitrophenyl)-6-(1-methyl-1H-indol-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-amine

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(1-methyl-1H-indol-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(6-(1-methyl-1H-indol-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)-2-nitrobenzene-1,4-diamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 0.666667h; Microwave irradiation;99%

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