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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:White or

3,4-Methylenedioxyaniline

Cas:14268-66-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic 3,4-METHYLENEDIOXYANILINE 14268-66-7 Manufacturer

Cas:14268-66-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,4-(Methylenedioxy)-aniline

Cas:14268-66-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 3,4-(Methylenedioxy)aniline Synonyms: benzo[d][1,3]dioxol-5-amine;5-Amino-1,3-benzodioxole 98%;1,3-Benzodioxol-5-amine, 3,4-(Methylenedioxy)aniline;3,4-(Methylenedioxy)aniline, 97% 10GR;3,4-(Methylenedioxy)aniline

14268-66-7 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3,4-(Methylenedioxy)aniline CAS 14268-66-7

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 14268-66-7 with best quality

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,4-(Methylenedioxy)aniline 14268-66-7

Cas:14268-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3,4-(Methylenedioxy)aniline Synonyms: benzo[d][1,3]dioxol-5-amine;5-Amino-1,3-benzodioxole 98%;1,3-Benzodioxol-5-amine, 3,4-(Methylenedioxy)aniline;5-Amino-1,3-benzodioxole 4-Amino-1,2-methylenedioxybenzene;3,4-METHYLENEDIOXYANILI

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 3,4-(Methylenedioxy)aniline CAS:14268-66-7

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $268.0 / 271.0

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-Methylenedioxyaniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 15.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3,4-Methylenedioxyaniline

Cas:14268-66-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

14268-66-7 C7H7NO2 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceuti

Benzo[d][1,3]dioxol-5-amine Manufacturer/High quality/Best price/In stock CAS NO.14268-66-7

Cas:14268-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

14268-66-7 C7H7NO2 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

14268-66-7 C7H7NO2 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

14268-66-7 C7H7NO2 3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,4-(Methylenedioxy)aniline cas no. 14268-66-7 98%

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

Benzo[d][1,3]dioxol-5-aMine

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3,4-(Methylenedioxy)aniline

Cas:14268-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

N-(3,4-methylendioxyphenyl)-N-benzylamine
32932-20-0

N-(3,4-methylendioxyphenyl)-N-benzylamine

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With formic acid; potassium hydroxide In ethanol at 70℃; for 1h; Catalytic behavior; Reagent/catalyst;97%
5-nitro-1,3-benzodioxole
2620-44-2

5-nitro-1,3-benzodioxole

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With C30H29BrMnNO2P2; hydrogen; potassium carbonate In toluene at 130℃; under 60006 Torr; for 24h; Glovebox; Autoclave; chemoselective reaction;96%
With hydrogen; nickel In ethanol at 60℃; under 18751.9 Torr; for 2h; Solvent; Pressure; Concentration;95.9%
With C36H56Cl3CrN2O; magnesium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In tetrahydrofuran at 60℃; for 24h; Inert atmosphere;85%
1,2-(methylenedioxy)-4-bromobenzene
2635-13-4

1,2-(methylenedioxy)-4-bromobenzene

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With copper(I) oxide; ammonium hydroxide; C17H14N2O3; potassium hydroxide In ethanol at 60℃; for 24h; Schlenk technique; Inert atmosphere;95%
With ammonium hydroxide; copper(l) iodide; N,N-dimethylethylenediamine In dimethyl sulfoxide at 130℃; for 18h; Reagent/catalyst; Time; Sealed tube; Inert atmosphere;90%
With diethylenetriaminopentaacetic acid; ammonia; copper(II) oxide; potassium hydroxide In water at 100℃; for 12h;73%
With ammonium hydroxide; diethylenetriaminopentaacetic acid; copper(II) oxide; potassium hydroxide In water at 100℃; for 12h; Sealed tube;73%
Stage #1: 1,2-(methylenedioxy)-4-bromobenzene With magnesium In tetrahydrofuran Inert atmosphere;
Stage #2: With C10H17NO In tetrahydrofuran; toluene at -78℃; for 2h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; water; toluene Inert atmosphere;
66%
5-iodo-1,3-benzodioxole
5876-51-7

5-iodo-1,3-benzodioxole

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With copper(I) oxide; ammonium hydroxide; N1-(furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide; potassium hydroxide In ethanol at 80℃; for 24h; Schlenk technique; Inert atmosphere;95%
C11H9NO4

C11H9NO4

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With chloro-trimethyl-silane; cyclopentadienyl titanium(IV) trichloride; magnesium; triethylamine In tetrahydrofuran at 50℃; for 15h;93%
3,4-(methylenedioxy)-benzeneboronic acid
94839-07-3

3,4-(methylenedioxy)-benzeneboronic acid

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With sodium hydroxide; hydroxylamine-O-sulfonic acid In acetonitrile at 20℃; for 16h;90%
Methylenedioxybenzene
274-09-9

Methylenedioxybenzene

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; iron(II) bromide; silver(I) triflimide In 2,2,2-trifluoroethanol; water at 30℃; for 2h;60%
Stage #1: Methylenedioxybenzene With sulfuric acid; hydroxylamine hydrochloride In acetonitrile at 25℃; for 0.166667h;
Stage #2: With hydrogenchloride; titanium(III) chloride In water; acetonitrile at 25℃; Inert atmosphere; Sealed tube;
57%
1-(benzo[d][1,3]dioxole-5-carbonyl)piperidine-2,6-dione

1-(benzo[d][1,3]dioxole-5-carbonyl)piperidine-2,6-dione

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
Stage #1: 1-(benzo[d][1,3]dioxole-5-carbonyl)piperidine-2,6-dione With Benzophenone imine; 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; Ni(1,5-cyclooctadiene)2; lithium chloride In toluene at 170℃; Glovebox; Inert atmosphere; Sealed tube;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃;
55%
2-(benzo[d][1,3]dioxol-5-yloxy)propanamide
1181403-64-4

2-(benzo[d][1,3]dioxol-5-yloxy)propanamide

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide at 140℃; for 8h; Green chemistry;48%
C20H15NO2

C20H15NO2

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran at 20℃;40%
3,4-methylenedioxybenzamide
4847-94-3

3,4-methylenedioxybenzamide

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With sodium hydroxide; alkaline aqueous sodium hypochlorite solution
With alkaline alkali hypobromite solution
Methylenedioxybenzene
274-09-9

Methylenedioxybenzene

A

benzo[d][1,3]dioxol-4-amine
1668-84-4

benzo[d][1,3]dioxol-4-amine

B

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With sulfuric acid; hydroxylamine-O-sulfonic acid; iron(II) sulfate In water; N,N-dimethyl-formamide at 30 - 35℃; for 1h; Yield given. Yields of byproduct given;
2,4-dinitroso-2,4-diaza-glutaric acid diethyl ester
857829-30-2

2,4-dinitroso-2,4-diaza-glutaric acid diethyl ester

4-amino-1.2-dioxy-benzene hydrochloride

4-amino-1.2-dioxy-benzene hydrochloride

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With potassium hydroxide; diethyl ether
4-nitro-pyrocatechol-methylene ether

4-nitro-pyrocatechol-methylene ether

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With hydrogenchloride; tin
3,4-methylenedioxybenzamide
4847-94-3

3,4-methylenedioxybenzamide

potassium hypobromite

potassium hypobromite

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
beim Erhitzen;
6-nitrobenzo[d][1,3]dioxole-5-carboxylic acid
716-32-5

6-nitrobenzo[d][1,3]dioxole-5-carboxylic acid

A

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

B

6-amino-piperonylic acid

6-amino-piperonylic acid

Conditions
ConditionsYield
With hydrogenchloride; tin
2-benzo[1,3]dioxol-5-yl-1,1,1,3,3,3-hexamethyl-disilazane

2-benzo[1,3]dioxol-5-yl-1,1,1,3,3,3-hexamethyl-disilazane

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether
1-(benzo[d][1,3]dioxol-5-yl)urea

1-(benzo[d][1,3]dioxol-5-yl)urea

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
With sulfuric acid In methanol; water at 80 - 90℃; Kinetics; Further Variations:; Temperatures;
piperonylonitrile
4421-09-4

piperonylonitrile

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen peroxide; KOH-solution
2: alkaline alkali hypobromite solution
View Scheme
Piperonylic acid
94-53-1

Piperonylic acid

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogen chloride
2: aqueous ammonia / 60 - 80 °C / im Rohr
3: alkaline alkali hypobromite solution
View Scheme
Multi-step reaction with 3 steps
1.1: thionyl chloride / 2 h / Reflux
2.1: dmap; triethylamine / dichloromethane / 0 - 20 °C
3.1: Ni(1,5-cyclooctadiene)2; Benzophenone imine; 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; lithium chloride / toluene / 170 °C / Glovebox; Inert atmosphere; Sealed tube
3.2: 20 °C
View Scheme
methyl 3,4-methylenedioxybenzoate
326-56-7

methyl 3,4-methylenedioxybenzoate

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous ammonia / 60 - 80 °C / im Rohr
2: alkaline alkali hypobromite solution
View Scheme
acetic anhydride
108-24-7

acetic anhydride

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

3,4-methylenedioxyacetanilide
13067-19-1

3,4-methylenedioxyacetanilide

Conditions
ConditionsYield
In 1,4-dioxane at 0 - 20℃; for 1h;100%
With triethylamine In dichloromethane at 0℃; for 0.5h;97%
With acetic acid95%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

diethyl [[3,4-(methylenedioxy)phenylamino]methylene]malonate
17394-77-3

diethyl [[3,4-(methylenedioxy)phenylamino]methylene]malonate

Conditions
ConditionsYield
In ethanol at 90℃; for 18h;100%
In benzene for 3.5h; Reflux;96%
In benzene for 3.5h; Heating;71%
In benzene for 3h; Reflux;
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

acetone
67-64-1

acetone

N-isopropyl-3,4-(methylenedioxy)aniline
10368-14-6

N-isopropyl-3,4-(methylenedioxy)aniline

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 17h;100%
With sodium tris(acetoxy)borohydride; acetic acid In tetrahydrofuran for 15h; Ambient temperature;
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

6,7-dimethoxy-4-(1-piperazinyl)quinazoline
21584-72-5

6,7-dimethoxy-4-(1-piperazinyl)quinazoline

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

4-(6,7-dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid benzo[1,3]dioxol-5-ylamide

4-(6,7-dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid benzo[1,3]dioxol-5-ylamide

Conditions
ConditionsYield
Stage #1: benzo[1,3]dioxolo-5-ylamine; 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 4h;
Stage #2: 6,7-dimethoxy-4-(1-piperazinyl)quinazoline In dichloromethane at 20℃; Further stages.;
100%
glyoxylic acid ethyl ester
924-44-7

glyoxylic acid ethyl ester

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

ethyl 2-(benzo[1,3]dioxol-5-ylimino)acetate

ethyl 2-(benzo[1,3]dioxol-5-ylimino)acetate

Conditions
ConditionsYield
With magnesium sulfate In toluene at 25℃; for 0.5h;100%
In toluene at 23℃; for 1h; Molecular sieve; Inert atmosphere;
In dichloromethane for 0.333333h; Inert atmosphere;
benzaldehyde
100-52-7

benzaldehyde

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

C14H11NO2
32932-19-7

C14H11NO2

Conditions
ConditionsYield
In ethanol for 1h; Sonication;100%
In ethanol for 5h; Reflux;
In toluene for 6h; Reflux;
In neat (no solvent) at 20℃; for 0.5h; Schlenk technique; Molecular sieve; Inert atmosphere;
1,4-oxathiane-2,6-dione
3261-87-8

1,4-oxathiane-2,6-dione

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

C11H11NO5S

C11H11NO5S

Conditions
ConditionsYield
In dichloromethane at 20℃; for 24h;100%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

N-(benzo[d][1,3]dioxol-5-yl)-4-methylbenzenesulfonamide

N-(benzo[d][1,3]dioxol-5-yl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 4℃;100%
With pyridine at 0 - 20℃;96%
With silica gel at 20℃;92%
benzaldehyde
100-52-7

benzaldehyde

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

N-(3,4-methylendioxyphenyl)-N-benzylamine
32932-20-0

N-(3,4-methylendioxyphenyl)-N-benzylamine

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 17h;100%
With tetra(n-butyl)ammonium hydrogensulfate; dimethyl sulfoxide at 20℃; for 5h; Electrolysis;30%
With sodium triacetoxy borohydride; acetic acid In dichloromethane at 0 - 20℃;
Multi-step reaction with 2 steps
1: neat (no solvent) / 0.5 h / 20 °C / Schlenk technique; Molecular sieve; Inert atmosphere
2: 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane / neat (no solvent) / 24 h / 20 °C / Schlenk technique; Inert atmosphere
View Scheme
1,3-cyclopentadione
3859-41-4

1,3-cyclopentadione

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

3-(Benzo[1,3]dioxol-5-ylamino)-cyclopent-2-enone

3-(Benzo[1,3]dioxol-5-ylamino)-cyclopent-2-enone

Conditions
ConditionsYield
In 1,4-dioxane Ambient temperature;99%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

diisopropylamine
108-18-9

diisopropylamine

N-isopropyl-3,4-(methylenedioxy)aniline
10368-14-6

N-isopropyl-3,4-(methylenedioxy)aniline

Conditions
ConditionsYield
With μ-diiodo-di((η5-pentamethylcyclopentadienyl)(iodo)iridium) In 5,5-dimethyl-1,3-cyclohexadiene at 155℃; for 10h; Inert atmosphere;99%
2-Hydroxy-1,4-naphthoquinone
83-72-7

2-Hydroxy-1,4-naphthoquinone

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

12-(4-methylphenyl)-5,10-dihydro-benzo[i][1,3]dioxolo[4,5-b]acridine-6,11-dione

12-(4-methylphenyl)-5,10-dihydro-benzo[i][1,3]dioxolo[4,5-b]acridine-6,11-dione

Conditions
ConditionsYield
With L-proline In ethanol for 1h; Reflux; Green chemistry;99%
ethanol
64-17-5

ethanol

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

N-ethyl-3,4-(methylenedioxy)aniline
32953-14-3

N-ethyl-3,4-(methylenedioxy)aniline

Conditions
ConditionsYield
With cesiumhydroxide monohydrate; (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3 at 110℃; Schlenk technique; Inert atmosphere;99%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

2-fluoro-4-methylbenzoic Acid
7697-23-6

2-fluoro-4-methylbenzoic Acid

N-(benzo[d][1,3]dioxol-5-yl)-2-fluoro-4-methylbenzamide

N-(benzo[d][1,3]dioxol-5-yl)-2-fluoro-4-methylbenzamide

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h;99%
5-methylene-4-phenyl-4-vinyl-1,3-dioxolan-2-one

5-methylene-4-phenyl-4-vinyl-1,3-dioxolan-2-one

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

1-(benzo[d][1,3]dioxol-5-yl)-2-methyl-3-phenyl-1H-pyrrole

1-(benzo[d][1,3]dioxol-5-yl)-2-methyl-3-phenyl-1H-pyrrole

Conditions
ConditionsYield
With palladium(II) trifluoroacetate; trifuran-2-yl-phosphane In dichloromethane at 20℃; for 12h;99%
[5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]acetic acid
1184304-26-4

[5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]acetic acid

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

N-(benzo[1,3]dioxol-5-yl)-2-[5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-acetamide
1184304-64-0

N-(benzo[1,3]dioxol-5-yl)-2-[5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-acetamide

Conditions
ConditionsYield
Stage #1: [5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]acetic acid With triethylamine In tetrahydrofuran at -5 - 0℃;
Stage #2: With chloroformic acid ethyl ester In tetrahydrofuran at 0℃; for 1h;
Stage #3: benzo[1,3]dioxolo-5-ylamine In tetrahydrofuran at 20℃; for 12h;
98%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

3-(2,2,2-trifluoroacetyl)-4H-chromen-4-one
160856-31-5

3-(2,2,2-trifluoroacetyl)-4H-chromen-4-one

3-{[(1,3-benzodioxol-5-yl)amino]methylene}-2-hydroxy-2-(trifluoromethyl)chroman-4-one

3-{[(1,3-benzodioxol-5-yl)amino]methylene}-2-hydroxy-2-(trifluoromethyl)chroman-4-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 60℃;98%
chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

ethyl (1,3-benzodioxolan-5-yl)carbamate
165330-00-7

ethyl (1,3-benzodioxolan-5-yl)carbamate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 0.5h;98%
With triethylamine In tetrahydrofuran at 20℃; for 4h;85%
With triethylamine In tetrahydrofuran at 20℃; for 0.5h;
With triethylamine In tetrahydrofuran at 20℃; for 0.5h;
formaldehyd
50-00-0

formaldehyd

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

N-methyl-3,4-(methylenedioxy)aniline
34060-22-5

N-methyl-3,4-(methylenedioxy)aniline

Conditions
ConditionsYield
Stage #1: formaldehyd; benzo[1,3]dioxolo-5-ylamine With sodium methylate In methanol at 20℃; for 24h;
Stage #2: With methanol; sodium tetrahydroborate at 40℃; for 3h;
98%
Stage #1: formaldehyd; benzo[1,3]dioxolo-5-ylamine With sodium methylate In methanol at 20℃; for 18h;
Stage #2: With sodium tetrahydroborate In methanol at 40℃; for 3h;
1.43 g
piperonal
120-57-0

piperonal

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

diallyl phosphite
23679-20-1

diallyl phosphite

diallyl (benzo[d][1,3]dioxol-5-yl(benzo[d][1,3]dioxol-5-ylamino)methyl)phosphonate
1449479-35-9

diallyl (benzo[d][1,3]dioxol-5-yl(benzo[d][1,3]dioxol-5-ylamino)methyl)phosphonate

Conditions
ConditionsYield
With Amberlite-IR 120 for 0.0166667h; Microwave irradiation;98%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

N-(benzo[d][1,3]dioxol-5-yl)methanesulfonamide

N-(benzo[d][1,3]dioxol-5-yl)methanesulfonamide

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; for 12h;98%
With silica gel at 20℃;95%
Stage #1: benzo[1,3]dioxolo-5-ylamine With triethylamine In dichloromethane at 20℃; for 0.166667h;
Stage #2: methanesulfonyl chloride In dichloromethane at 20℃; for 24h;
89.2%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

tetraacetoxysilane
562-90-3

tetraacetoxysilane

3,4-methylenedioxyacetanilide
13067-19-1

3,4-methylenedioxyacetanilide

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 4h;98%
4-hydroxy-2(5H)-furanone
541-57-1

4-hydroxy-2(5H)-furanone

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

9-(4-methoxyphenyl)-6,9-dihydro-[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one

9-(4-methoxyphenyl)-6,9-dihydro-[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one

Conditions
ConditionsYield
Inert atmosphere; Reflux;97%
methanol
67-56-1

methanol

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

N-methyl-3,4-(methylenedioxy)aniline
34060-22-5

N-methyl-3,4-(methylenedioxy)aniline

Conditions
ConditionsYield
With cesiumhydroxide monohydrate; (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3 at 110℃; Schlenk technique; Inert atmosphere;97%
With dimanganese decacarbonyl; potassium tert-butylate In toluene at 100℃; for 24h; Inert atmosphere; Sealed tube;92%
With potassium tert-butylate; C38H37ClN2PRu(1+)*C32H12BF24(1-) In neat (no solvent) at 110℃; for 12h; Sealed tube; Inert atmosphere; Schlenk technique; Green chemistry;92%
benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

benzyl alcohol
100-51-6

benzyl alcohol

N-(3,4-methylendioxyphenyl)-N-benzylamine
32932-20-0

N-(3,4-methylendioxyphenyl)-N-benzylamine

Conditions
ConditionsYield
With C50H38ClN3O2P2RuS; potassium hydroxide In toluene at 100℃; for 12h;97%
With iron(III) oxide; potassium hydroxide In toluene at 135℃; for 24h; Inert atmosphere; Sealed tube;80%
With zinc(II) nitrate hexahydrate; potassium tert-butylate In toluene at 140℃; for 36h; Sealed tube; Inert atmosphere; Schlenk technique;72%
isatoic anhydride
118-48-9

isatoic anhydride

2-Formylphenoxyacetic acid
6280-80-4

2-Formylphenoxyacetic acid

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

2-(phenoxyacetic acid-2-yl)-3-(benzo[d]-[1,3]dioxol-5-yl)-2,3-dihydroquinazolin-4(1H)-one

2-(phenoxyacetic acid-2-yl)-3-(benzo[d]-[1,3]dioxol-5-yl)-2,3-dihydroquinazolin-4(1H)-one

Conditions
ConditionsYield
With ethylenediaminediacetic acid In water for 12h; Reflux;96.4%
tetrahydrofuran-2,4-dione
4971-56-6

tetrahydrofuran-2,4-dione

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

4-(benzo[d][1,3]dioxol-5-ylamino)furan-2(5H)-one
200053-21-0

4-(benzo[d][1,3]dioxol-5-ylamino)furan-2(5H)-one

Conditions
ConditionsYield
In acetonitrile for 0.666667h; Microwave irradiation; Reflux;96%
In 1,4-dioxane Product distribution; Ambient temperature; var. anilines;
In 1,4-dioxane Ambient temperature;
piperonal
120-57-0

piperonal

benzo[1,3]dioxolo-5-ylamine
14268-66-7

benzo[1,3]dioxolo-5-ylamine

mercaptoacetic acid
68-11-1

mercaptoacetic acid

C17H13NO5S
1129572-76-4

C17H13NO5S

Conditions
ConditionsYield
In water at 110℃; for 0.15h; Microwave irradiation; chemoselective reaction;96%

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