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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-METHYLBENZO[B]THIOPHENE

Cas:14315-11-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzo[b]thiophene,4-methyl- 14315-11-8

Cas:14315-11-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

4-METHYLBENZOTHIOPHENE CAS:14315-11-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

4-METHYLBENZOTHIOPHENE CAS:14315-11-8

Cas:14315-11-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-Methylbenzo[b]thiophene CAS NO.14315-11-8

Cas:14315-11-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

4-methylbenzo[b]thiophene Application:4-methylbenzo[b]thiophene

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Other

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

14315-11-8

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

4-methylbenzo[b]thiopheneAppearance:ask Storage:Keep in dry and cool condition Package:foil aluminium bag/vacuum packing Application:intermediates Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to ai

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NUTROCHEM- MANUFACTURE PLACE

best seller Application:API

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

4-Methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

4-Methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

4-METHYLBENZO[B]THIOPHENE CAS NO.14315-11-8

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jusheng Technology Co., Ltd.,

1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:10 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

4-METHYLBENZOTHIOPHENE

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Other

inquiry

changchun tuocai technology co.,ltld

4-methylbenzo[b]thiopheneAppearance:ask Storage:Keep in dry and cool condition Package:foil aluminium bag/vacuum packing Application:intermediates Transportation:by air or by sea

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Taizhou volsen chemical Co., Ltd

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

4-methylbenzo[b]thiophene

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Raymon Biotech Co., Ltd.

Benzo[b]thiophene,4-methyl- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shenzhen

Benzo[b]thiophene,4-methyl-

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Minshang Biotechnology Co., Ltd

4-methylbenzo[b]thiophene Application:intermediates

14315-11-8

Cas:14315-11-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-methylbenzo[b]thiophene-2-carboxylic acid
1735-13-3

4-methylbenzo[b]thiophene-2-carboxylic acid

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl acetamide at 200℃; for 1h; microwave irradiation;100%
2,3-thiophenedicarboxylic acid anhydride
6007-83-6

2,3-thiophenedicarboxylic acid anhydride

cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

A

6-methylbenzo[b]thiophene
16587-47-6

6-methylbenzo[b]thiophene

B

5-methylthianaphthene
14315-14-1

5-methylthianaphthene

C

7-methyl-benzo[b]thiophene
14315-15-2

7-methyl-benzo[b]thiophene

D

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
at 500℃; Further byproducts given. Title compound not separated from byproducts;A n/a
B n/a
C 5.8%
D 6.8%
at 500℃; under 1 - 5 Torr; Further byproducts given. Title compound not separated from byproducts;A n/a
B n/a
C 5.8%
D 6.8%
at 500℃; under 1 - 5 Torr; Further byproducts given;A n/a
B n/a
C 5.8%
D 6.8%
1-methyl-2-vinyl-benzene
611-15-4

1-methyl-2-vinyl-benzene

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
With iron oxide-aluminium oxide; hydrogen sulfide at 600℃;
m-tolylsulfanyl-acetaldehyde diethylacetal
51830-51-4

m-tolylsulfanyl-acetaldehyde diethylacetal

A

6-methylbenzo[b]thiophene
16587-47-6

6-methylbenzo[b]thiophene

B

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
K10-ZnCl2 In gas at 300℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With K10-ZnCl2 at 300℃; under 0.03 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With phosphoric acid
(+-)-4-methyl-4,5,6,7-tetrahydro-benzo<b>thiophen-4-ol

(+-)-4-methyl-4,5,6,7-tetrahydro-benzo<b>thiophen-4-ol

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
With sulfur at 250℃;
phosphoric acid
86119-84-8, 7664-38-2

phosphoric acid

m-tolylsulfanyl-acetaldehyde diethylacetal
51830-51-4

m-tolylsulfanyl-acetaldehyde diethylacetal

P2O5

P2O5

A

6-methylbenzo[b]thiophene
16587-47-6

6-methylbenzo[b]thiophene

B

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

2-mercapto-3-o-tolyl-acrylic acid

2-mercapto-3-o-tolyl-acrylic acid

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / iodine / dioxane / 0.13 h / 180 °C / microwave irradiation
2: 100 percent / DBU / N,N-dimethyl-acetamide / 1 h / 200 °C / microwave irradiation
View Scheme
4-methylene-4,5,6,7-tetrahydro-benzo[b]thiophene

4-methylene-4,5,6,7-tetrahydro-benzo[b]thiophene

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

Conditions
ConditionsYield
palladium In toluene
6-methylbenzo[b]thiophene
16587-47-6

6-methylbenzo[b]thiophene

4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

6-methyl-2,3-dihydrobenzo[b]thiophene
14450-24-9

6-methyl-2,3-dihydrobenzo[b]thiophene

A

6-methyl-benzo[b]thiophene-4,7-quinone

6-methyl-benzo[b]thiophene-4,7-quinone

B

6-methyl-2,3-dihydro-benzo[b]thiophene-1,1-dioxide

6-methyl-2,3-dihydro-benzo[b]thiophene-1,1-dioxide

Conditions
ConditionsYield
mit Chrom(VI)-oxid und wasserhaltiger Essigsaeure;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

1,1'-dichloro-2,2'-difluoroethene
79-35-6

1,1'-dichloro-2,2'-difluoroethene

2-(2,2-dichloro-1-fluoroethenyl)-4-methylbenzothiophene

2-(2,2-dichloro-1-fluoroethenyl)-4-methylbenzothiophene

Conditions
ConditionsYield
With n-butyllithium 1.) n-hexane, diethyl ether, from 0 deg C to RT, 2.) n-hexane, diethyl ether, from 0 deg C to RT; Multistep reaction;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

allyl bromide
106-95-6

allyl bromide

2-allyl-4-methylbenzothiophene
89816-54-6

2-allyl-4-methylbenzothiophene

Conditions
ConditionsYield
With n-butyllithium 1. ether, -50 - -70 degC, 30min; 2. ether, r.t., overnight; Yield given. Multistep reaction;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

4-Bromomethyl-benzo[b]thiophene
10133-19-4

4-Bromomethyl-benzo[b]thiophene

Conditions
ConditionsYield
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane Heating;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

2-chloro-4-methylbenzothiophene

2-chloro-4-methylbenzothiophene

Conditions
ConditionsYield
With n-butyllithium; chlorine 1.) ether, hexane, 0 deg C, 1 h, 2.) RT, 1 h; Multistep reaction;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

2,3-dichloro-4-methylbenzothiophene
130220-07-4

2,3-dichloro-4-methylbenzothiophene

Conditions
ConditionsYield
With chlorine In tetrachloromethane for 3h; Ambient temperature;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

toluene
108-88-3

toluene

A

4-methyl-2-phenyl-2,3-dihydrobenzothiophen
80823-89-8

4-methyl-2-phenyl-2,3-dihydrobenzothiophen

B

4-methyl-3-phenyl-2,3-dihydrobenzothiophen
80823-99-0

4-methyl-3-phenyl-2,3-dihydrobenzothiophen

C

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

toluene
108-88-3

toluene

A

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen
80823-84-3

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen

B

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen
80823-94-5

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen

C

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

toluene
108-88-3

toluene

A

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen
80823-94-5

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen

B

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

C

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride at 20℃; for 0.5h; Product distribution; other reagent (benzene);
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

benzene
71-43-2

benzene

A

4-methyl-2-phenyl-2,3-dihydrobenzothiophen
80823-89-8

4-methyl-2-phenyl-2,3-dihydrobenzothiophen

B

4-methyl-3-phenyl-2,3-dihydrobenzothiophen
80823-99-0

4-methyl-3-phenyl-2,3-dihydrobenzothiophen

C

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

A

2,3-Dihydro-4-methylbenzothiophene
80824-38-0

2,3-Dihydro-4-methylbenzothiophene

B

4-methyl-2-phenyl-2,3-dihydrobenzothiophen
80823-89-8

4-methyl-2-phenyl-2,3-dihydrobenzothiophen

C

4-methyl-3-phenyl-2,3-dihydrobenzothiophen
80823-99-0

4-methyl-3-phenyl-2,3-dihydrobenzothiophen

D

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride; benzene at 20℃; for 0.5h; Further byproducts given;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

A

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen
80823-84-3

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen

B

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen
80823-94-5

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen

C

4,4'-Dimethyl-2,3-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride; toluene at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

A

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen
80823-84-3

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen

B

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen
80823-94-5

4-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen

C

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride; toluene at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

A

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen
80823-84-3

4-methyl-2-(p-tolyl)-2,3-dihydrobenzothiophen

B

4,4'-Dimethyl-2,3-dihydro-[2,2']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[2,2']bi[benzo[b]thiophenyl]

C

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2',3'-dihydro-[2,3']bi[benzo[b]thiophenyl]

D

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

4,4'-Dimethyl-2,3-dihydro-[3,3']bi[benzo[b]thiophenyl]

Conditions
ConditionsYield
With aluminium trichloride; toluene at 20℃; for 0.5h; Further byproducts given. Title compound not separated from byproducts;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

4-hydroxy-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine-1-carboxylic acid tert-butyl ester

4-hydroxy-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78℃;
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate
190906-92-4

tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate

4-hydroxy-2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine-1-carboxylic acid tert-butyl ester

4-hydroxy-2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 4-methylbenzo[b]thiophene With n-butyllithium In tetrahydrofuran at -78℃;
Stage #2: tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine

2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: n-BuLi / tetrahydrofuran / -78 °C
1.2: tetrahydrofuran
2.1: TFA / CH2Cl2
2.2: H2 / Pd/C / ethanol; 2,2,2-trifluoro-ethanol
View Scheme
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

4-(4-methyl-benzo[b]thiophen-2-yl)-1,2,3,6-tetrahydro-pyridine

4-(4-methyl-benzo[b]thiophen-2-yl)-1,2,3,6-tetrahydro-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: n-BuLi / tetrahydrofuran / -78 °C
2: TFA / CH2Cl2
View Scheme
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

4-(4-methylbenzo[b]thiophen-2-yl)piperidine
346592-96-9

4-(4-methylbenzo[b]thiophen-2-yl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: n-BuLi / tetrahydrofuran / -78 °C
2: TFA / CH2Cl2
3: H2 / 10 percent Pd/C / ethanol; 2,2,2-trifluoro-ethanol
View Scheme
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

1-(1H-indol-4-yloxy)-3-[4-(4-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol
574706-08-4

1-(1H-indol-4-yloxy)-3-[4-(4-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: n-BuLi / tetrahydrofuran / -78 °C
2: TFA / CH2Cl2
3: H2 / 10 percent Pd/C / ethanol; 2,2,2-trifluoro-ethanol
4: methanol / Heating
View Scheme
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

(2S)-1-(1H-indol-4-yl)oxy-3-[(2S,4R)-4-(4-methylbenzo[b]thiophen-2-yl)-2-methylpiperidinyl]-2-propanol
346589-06-8

(2S)-1-(1H-indol-4-yl)oxy-3-[(2S,4R)-4-(4-methylbenzo[b]thiophen-2-yl)-2-methylpiperidinyl]-2-propanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-BuLi / tetrahydrofuran / -78 °C
1.2: tetrahydrofuran
2.1: TFA / CH2Cl2
2.2: H2 / Pd/C / ethanol; 2,2,2-trifluoro-ethanol
3.1: methanol / Heating
View Scheme
4-methylbenzo[b]thiophene
14315-11-8

4-methylbenzo[b]thiophene

(2S)-(-)-1-(1H-indol-4-yl)oxy-3-[(2R,4S)-4-(4-methylbenzo[b]thiophen-2-yl)-2-methylpiperidinyl]-2-propanol
346591-10-4

(2S)-(-)-1-(1H-indol-4-yl)oxy-3-[(2R,4S)-4-(4-methylbenzo[b]thiophen-2-yl)-2-methylpiperidinyl]-2-propanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-BuLi / tetrahydrofuran / -78 °C
1.2: tetrahydrofuran
2.1: TFA / CH2Cl2
2.2: H2 / Pd/C / ethanol; 2,2,2-trifluoro-ethanol
3.1: methanol / Heating
View Scheme

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