SAGECHEM is a chemical R&D, manufacturing, distribution and our own import and export right company in China since 2009,, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a
Cas:1445-07-4
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inquiryBOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals.
NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
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inquiry1. We integrate research and development, production, and sales. A 1800 square meter research and development center,The company has conducted over 50 research and development and technical service projects annually, applied for more than 10 patents,
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inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryManufacturer supply Pseudouridine CAS 1445-07-4 with competitive price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Fee
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryAbout Product Technical Details
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FOB Price: $1.0 / 3.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:1445-07-4
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inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:1445-07-4
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inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
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inquiryBETA-PSEUDOURIDINE CAS:1445-07-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryWhy Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:1445-07-4
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inquiryOur Strength:-Flexible: We work in small teams with rapid communication channels. Respond quickly and efficiently to customer and market needs.-Innovative: We are focusing on the development of new products and keep close relationships with our custo
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:1445-07-4
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FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:1445-07-4
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:1445-07-4
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Type:Trading Company
inquiryWuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
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inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:1445-07-4
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Type:Trading Company
inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:1445-07-4
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inquiryTAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine
pseudouridine
Conditions | Yield |
---|---|
With trifluoroacetic acid at 20℃; for 1h; | 100% |
pseudouridine
Conditions | Yield |
---|---|
at 70℃; for 2h; pH=9; | 100% |
5-(2,3-O-isopropylidene-β-D-ribofuranosyl)uracil
pseudouridine
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 20℃; for 5h; | 93% |
2,4-Di-tert-butoxy-5-[(3aS,4S,6R,6aR)-6-(1-methoxy-1-methyl-ethoxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-pyrimidine
pseudouridine
Conditions | Yield |
---|---|
With acetic acid at 50℃; for 5h; | 93% |
(2S,3S,4R,5R)-2-(2,4-dimethoxypyrimidin-5-yl)-5-hydroxymethyltetrahydrofuran-3,4-diol
pseudouridine
Conditions | Yield |
---|---|
With acetic acid; sodium iodide for 0.75h; Inert atmosphere; Reflux; | 90% |
5-((3S,4R,5R)-3,4-Dimethoxy-5-methoxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
A
pseudouridine
B
α-pseudouridine
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane at -78℃; for 144h; | A 53% B n/a |
5-((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
A
pseudouridine
B
α-pseudouridine
Conditions | Yield |
---|---|
With boron trichloride In dichloromethane at -78℃; | A 42% B n/a |
With boron trichloride In dichloromethane at -78℃; Yields of byproduct given; |
(1S)-tri-O-acetyl-1-(2,4-bis-methylsulfanyl-pyrimidin-5-yl)-D-1,4-anhydro-ribitol
pseudouridine
Conditions | Yield |
---|---|
(i) MCPBA, (ii) H2O, (iii) NaOMe, MeOH; Multistep reaction; |
(1Ξ)-O2,O4;O3,O5-(R,R)-dibenzylidene-1-(2,4-bis-benzyloxy-pyrimidin-5-yl)-D-ribitol
A
(Ξ)-5-ξ-D-ribopyranosyl-pyrimidine-2,4-dione
B
pseudouridine
C
α-pseudouridine
Conditions | Yield |
---|---|
(i) BBr3, THF, (ii) MeOH, CH2Cl2; Multistep reaction; |
(2S,3R,4R)-2,3,5-Tris-benzyloxy-1-(2,4-di-tert-butoxy-pyrimidin-5-yl)-pentane-1,4-diol
A
pseudouridine
B
α-pseudouridine
Conditions | Yield |
---|---|
With boron trichloride In dichloromethane at -78℃; for 18h; |
5'-O-(tert-butyldiphenylsilyl)pseudouridine
pseudouridine
Conditions | Yield |
---|---|
With hydrogenchloride In methanol for 4h; Desilylation; |
2,3-O-isopropylidene-5-O-(1-methoxy-1-methyl-ethyl)-D-ribono-1,4-lactone
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 89 percent / tetrahydrofuran / -78 °C 2: 85 percent / L-Selectride; ZnCl2 / CH2Cl2; tetrahydrofuran; diethyl ether / -78 - 20 °C 3: 70 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 4 °C 4: 93 percent / aq. acetic acid / 5 h / 50 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 94 percent / pyridinium p-toluenesulfonate; sodium sulfate / 1 h / 60 °C 2: 89 percent / tetrahydrofuran / -78 °C 3: 85 percent / L-Selectride; ZnCl2 / CH2Cl2; tetrahydrofuran; diethyl ether / -78 - 20 °C 4: 70 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 4 °C 5: 93 percent / aq. acetic acid / 5 h / 50 °C View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 85 percent / L-Selectride; ZnCl2 / CH2Cl2; tetrahydrofuran; diethyl ether / -78 - 20 °C 2: 70 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 4 °C 3: 93 percent / aq. acetic acid / 5 h / 50 °C View Scheme |
(R)-1-{(4R,5S)-5-[(R)-(2,4-Di-tert-butoxy-pyrimidin-5-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-(1-methoxy-1-methyl-ethoxy)-ethanol
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 70 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 4 °C 2: 93 percent / aq. acetic acid / 5 h / 50 °C View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: CH3COOH / 1 h / Heating 2: NaI / acetic acid / 0.42 h / Heating 3: HCl / methanol / 4 h View Scheme |
(2R,3S,4R,5S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(2,4-dimethoxy-pyrimidin-5-yl)-tetrahydro-furan-3,4-diol
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaI / acetic acid / 0.42 h / Heating 2: HCl / methanol / 4 h View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: BF3*Et2O; Et3SiH / CH2Cl2 / 1 h / 4 °C / 20 deg C 2: NaI / acetic acid / 0.42 h / Heating 3: HCl / methanol / 4 h View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 60 percent / C2H5ONa / ethanol / 5 h / Heating 2: 93 percent / HCl / methanol / 5 h / 20 °C View Scheme |
2-(2,4:3,5-di-O-benzylidenepentitol-1-yl)pyridine
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: (i) nBuLi, THF, (ii) /BRN= 1260242/ 2: (i) BBr3, THF, (ii) MeOH, CH2Cl2 View Scheme |
2-methylsulfanyl-pyrimidin-4-yl tri-O-acetyl-β-D-1-thio-ribofuranoside
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: (i) (UV-irradiation), (ii) /BRN= 969135/ 2: (i) MCPBA, (ii) H2O, (iii) NaOMe, MeOH View Scheme |
pseudoisocytidine
pseudouridine
Conditions | Yield |
---|---|
With acetic anhydride In pyridine; ethyl acetate | 3.2 g (85%) |
Conditions | Yield |
---|---|
With bacterial pseudouridine synthase TruB In aq. buffer at 37℃; Kinetics; Reagent/catalyst; Enzymatic reaction; |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 1H-imidazole / dichloromethane / 0 °C 2: sodium tetrahydroborate / methanol / 1 h / 0 °C 3: triethylamine / dichloromethane / 1 h / 0 - 20 °C 4: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 48 h / 0 - 75 °C 5: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetone / -20 °C 6: sodium iodide; acetic acid / 0.75 h / Inert atmosphere; Reflux View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: sodium tetrahydroborate / methanol / 1 h / 0 °C 2: triethylamine / dichloromethane / 1 h / 0 - 20 °C 3: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 48 h / 0 - 75 °C 4: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetone / -20 °C 5: sodium iodide; acetic acid / 0.75 h / Inert atmosphere; Reflux View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: triethylamine / dichloromethane / 1 h / 0 - 20 °C 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 48 h / 0 - 75 °C 3: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetone / -20 °C 4: sodium iodide; acetic acid / 0.75 h / Inert atmosphere; Reflux View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 48 h / 0 - 75 °C 2: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetone / -20 °C 3: sodium iodide; acetic acid / 0.75 h / Inert atmosphere; Reflux View Scheme |
pseudouridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / water; acetone / -20 °C 2: sodium iodide; acetic acid / 0.75 h / Inert atmosphere; Reflux View Scheme |
Conditions | Yield |
---|---|
In ethanol for 16h; pH=8.5; triethylammoniumbicarbonate buffer; | 98% |
With formic acid; triethylamine In ethanol; water for 16h; pH=8.5; | 98% |
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In ethanol for 16h; | 98% |
In ethanol for 16h; Triethylammonium-bicarbonate buffer; | 98% |
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
pseudouridine
3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)pseudouridine
Conditions | Yield |
---|---|
With pyridine at 0 - 20℃; | 97.8% |
In pyridine at 20℃; Cooling with ice; | 97.8% |
With pyridine at 0 - 20℃; | 94% |
acetic anhydride
pseudouridine
5-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrimidine-2,4-(1H,3H)-dione
Conditions | Yield |
---|---|
With dmap In N,N-dimethyl-formamide at -30℃; for 3h; | 95% |
With pyridine at 20℃; | 92% |
With pyridine Ambient temperature; |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 24h; Michael Addition; regioselective reaction; | 92% |
tert-butyldimethylsilyl chloride
pseudouridine
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide | 90% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 24h; Reagent/catalyst; Michael Addition; regioselective reaction; | 90% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 24h; Michael Addition; regioselective reaction; | 88% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 24h; Michael Addition; regioselective reaction; | 87% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 24h; Michael Addition; regioselective reaction; | 86% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 36h; Michael Addition; regioselective reaction; | 85% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 36h; Michael Addition; regioselective reaction; | 85% |
acrylonitrile
pseudouridine
A
C15H18N4O6
B
Monocyanoethylpseudouridin
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 45℃; for 24h; | A 9% B 84% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 36h; Michael Addition; regioselective reaction; | 84% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 36h; Michael Addition; regioselective reaction; | 82% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 36h; Michael Addition; regioselective reaction; | 82% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 48h; Michael Addition; regioselective reaction; | 77% |
N,N-dimethyl-formamide dimethyl acetal
pseudouridine
1,3-dimethyl-Ψ-uridine
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 110℃; for 1h; | 75.4% |
In dimethyl sulfoxide at 110℃; for 1h; | 75.4% |
Heating; | |
at 110℃; for 1h; | |
at 110℃; for 1h; |
4,4'-dimethoxytrityl chloride
pseudouridine
Conditions | Yield |
---|---|
With pyridine for 14h; Ambient temperature; | 73% |
With pyridine at 20℃; for 2h; | 58% |
Conditions | Yield |
---|---|
With pyridine at 20℃; for 24h; | 66% |
pseudouridine
mono-4-methoxytrityl chloride
Conditions | Yield |
---|---|
With pyridine at 20℃; for 15h; | 58% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 57% |
N-(3-iodopropyl)phthalimide
pseudouridine
A
C20H21N3O8
B
C31H30N4O10
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20 - 50℃; | A 25% B 37% |
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