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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-sec-butylcyclohexan-1-one

Cas:14765-30-1

Min.Order:1

Negotiable

Type:Other

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

2-SEC-BUTYLCYCLOHEXANONE Basic information Product Name: 2-SEC-BUTYLCYCLOHEXANONE Synonyms: 2-(1-methylpropyl)-cyclohexanon;2-sec-butyl-cyclohexanon;Cyclohexanone, sec.-butyl, # 2;Cycloh

TIANFU-CHEM CAS:14765-30-1 2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 14765-30-1 with competitive price

Cas:14765-30-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

About Our Group Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & c

China Biggest Factory Manufacturer Supply 2-SEC-BUTYLCYCLOHEXANONE CAS 14765-30-1

Cas:14765-30-1

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

2-(sec-butyl)cyclohexanone CAS NO.14765-30-1

Cas:14765-30-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-(sec-butyl)cyclohexanone CAS NO.14765-30-1 CAS NO.14765-30-1

Cas:14765-30-1

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-sec-butylcyclohexanone

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-sec-butylcyclohexanone

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-sec-Butylcyclohexanone (Mixture of isoMers)

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-sec-Butylcyclohexanone (Mixture of isoMers)

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

2-(1-METHYLPROPYL)CYCLOHEXANONE cas 14765-30-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-(1-METHYLPROPYL)CYCLOHEXANONE cas 14765-30-1

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Other

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

2-(sec-Butyl)cyclohexanone

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Other

inquiry

Jiangxi LinQ Spices Co.,Ltd.

Raw material ,higher purity, support by origional factory, fully large stock Basic information Product Name: 2-SEC-BUTYLCYCLOHEXANONE Synonyms: 2-sec-Butylcyclohexanone (mixture of isomers);2-sec-Butylcyclohexanone 2-sec-Butylcyclohexanone

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-(sec-Butyl)cyclohexanone

Cas:14765-30-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

2-(sec-butyl)cyclohexanone CAS NO.14765-30-1 CAS NO.14765-30-1

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Share Chemical Co., Ltd

At Share Chemical Company, we scrupulously abide by our policy of “Excellent Quality at a Reasonable Price”. We strive to satisfy all of our customers by providing the finest quality products supported by the finest in customer servi

2-sec-Butylcyclohexanone

Cas:14765-30-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Other

inquiry

Yueyang Juyuan Petrochemical Co., Ltd

1. Physical State Liquid 2. Appearance clear, colorless to pale yellow 3. Odor Acetone or peppermint odor FeaturesCyclohexanone is…

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 2-SEC-BUTYLCYCLOHEXANONE, CAS:14765-30-1 with the most competitive price and the best

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Sunrise Pharmaceutical Technology Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers. Package:According client's requirements Application:Pharmaceutical Intermediate Transportation:According client's requirements Port:SHA

2-(1-METHYLPROPYL)CYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai PotentPharm Science and Technology Co.,Ltd

1 good quality, better price and bettter service;2 Timely delivery;3 100% refunded if parcel is not delivered or poor quality.We will try to satisfy you upon receipt of your reply. I hope that we can become a long-term cooperative partner. Applicatio

2-(sec-Butyl)cyclohexanone

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synova( Tianjin ) Chemical Technology Co,.Ltd

The company have effective management team, professional technical R & D personnel, the service spirit of customer oriented. We have long-term cooperation with famous domestic manufacturer, and excellent customer resources overseas. We are skilled in

2-SEC-BUTYLCYCLOHEXANONE

Cas:14765-30-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

diethylzinc
557-20-0

diethylzinc

2-Eth-(E)-ylidene-cyclohexanone

2-Eth-(E)-ylidene-cyclohexanone

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

Conditions
ConditionsYield
With N-benzylbenzenesulfonamide; mesitylcopper(I) In toluene at 0℃; for 6h;90%
2,6-dibromocyclohexanone
34006-70-7

2,6-dibromocyclohexanone

lithium sec-butyl-(2-methyl-propan-2-olato)-cuprate(1-)

lithium sec-butyl-(2-methyl-propan-2-olato)-cuprate(1-)

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

Conditions
ConditionsYield
In tetrahydrofuran at -78℃;
2-(1-methylpropylidene)cyclohexanone
91055-78-6

2-(1-methylpropylidene)cyclohexanone

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

Conditions
ConditionsYield
With hydrogen; palladium
(Z)-2-Butene
590-18-1

(Z)-2-Butene

lithium 1-cyclohexenolate
21300-30-1

lithium 1-cyclohexenolate

A

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

B

2,6-di(sec-butyl)cyclohexanone
71501-12-7

2,6-di(sec-butyl)cyclohexanone

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
trans-2-Butene
624-64-6

trans-2-Butene

lithium 1-cyclohexenolate
21300-30-1

lithium 1-cyclohexenolate

A

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

B

2,6-di(sec-butyl)cyclohexanone
71501-12-7

2,6-di(sec-butyl)cyclohexanone

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
(E)-2-ethylidenecyclohexan-1-one
7417-55-2

(E)-2-ethylidenecyclohexan-1-one

Zn(C2H5)2

Zn(C2H5)2

A

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

B

1-ethyl-2-ethylidenecyclohexan-1-ol

1-ethyl-2-ethylidenecyclohexan-1-ol

Conditions
ConditionsYield
N-benzylbenzenesulfonamide; mesitylcopper(I) In toluene at 0℃; for 6h; Addition;A 90 % Chromat.
B n/a
1-acetoxy-6-bromo-cyclohexene
23029-03-0

1-acetoxy-6-bromo-cyclohexene

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Zn / tetrahydrofuran
2: H2 / Pd
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

naphthalene-1,8-diamine
479-27-6

naphthalene-1,8-diamine

C20H26N2

C20H26N2

Conditions
ConditionsYield
With toluene-4-sulfonic acid In propan-1-ol for 2h; Reflux;100%
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

aniline
62-53-3

aniline

(-)-N-(phenyl)-[2-sec-butylcyclohexyl]amine
1100691-75-5

(-)-N-(phenyl)-[2-sec-butylcyclohexyl]amine

Conditions
ConditionsYield
Stage #1: 2-sec-butylcyclohexanone; aniline With [(R)-BINAP]PdBr2 In chloroform for 0.166667h; Inert atmosphere;
Stage #2: With hydrogen In chloroform at 70℃; under 41372.9 Torr; for 24h; enantioselective reaction;
80%
dimethylsulfide
75-18-3

dimethylsulfide

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

3-(sec-butyl)-6-(methylthio)benzene-1,2-diol

3-(sec-butyl)-6-(methylthio)benzene-1,2-diol

Conditions
ConditionsYield
With iodine at 80℃; for 24h; Sealed tube;56%
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

4-methoxy-aniline
104-94-9

4-methoxy-aniline

N-(4-methoxyphenyl)-7-methyl-6-oxononanamide

N-(4-methoxyphenyl)-7-methyl-6-oxononanamide

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine; trifluorormethanesulfonic acid; oxygen In m-xylene at 130℃; under 760.051 Torr; for 8h; Sealed tube;47%
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

3-(sec-butyl)-6-(methylthio)benzene-1,2-diol

3-(sec-butyl)-6-(methylthio)benzene-1,2-diol

Conditions
ConditionsYield
With iodine at 80℃; for 24h; Sealed tube;42%
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

2-sec-butyl-1-chlorocyclohexene

2-sec-butyl-1-chlorocyclohexene

Conditions
ConditionsYield
With pyridine; bis(trichloromethyl) carbonate In dichloromethane at 35℃; for 24h;34%
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

7-sec-butyl-oxepan-2-one
104036-08-0

7-sec-butyl-oxepan-2-one

Conditions
ConditionsYield
With peracetic acid
Methyl dimethoxyacetate
89-91-8

Methyl dimethoxyacetate

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

2-sec-Butyl-6-(2,2-dimethoxy-acetyl)-cyclohexanone
144147-87-5

2-sec-Butyl-6-(2,2-dimethoxy-acetyl)-cyclohexanone

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight; Yield given. Multistep reaction;
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazole-3-carbaldehyde
144148-32-3

7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazole-3-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

7-sec-Butyl-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carbaldehyde

7-sec-Butyl-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-propenal
144149-56-4

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-propenal

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
4: (i-Bu)2AlH / tetrahydrofuran; toluene / 0.5 h
5: MnO2 / benzene / 2 h / Heating
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-prop-2-en-1-ol
162511-99-1

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-prop-2-en-1-ol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
4: (i-Bu)2AlH / tetrahydrofuran; toluene / 0.5 h
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

7-sec-Butyl-3-dimethoxymethyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazole

7-sec-Butyl-3-dimethoxymethyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: Et3N / ethanol / 20 - 78 °C
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

7-sec-Butyl-3-dimethoxymethyl-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole

7-sec-Butyl-3-dimethoxymethyl-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: Et3N / ethanol / 20 - 78 °C
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-acrylic acid ethyl ester
162511-74-2

(E)-3-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-acrylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

(E)-(3S,5R)-7-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester

(E)-(3S,5R)-7-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
4: (i-Bu)2AlH / tetrahydrofuran; toluene / 0.5 h
5: MnO2 / benzene / 2 h / Heating
6: tetrahydrofuran
7: 1.) Et3B, air, 2.) NaBH4 / 1.) MeOH, THF, 2 h, 2.) MeOH, THF, from -78 deg C to RT, overnight
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

(E)-7-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-5-hydroxy-3-oxo-hept-6-enoic acid ethyl ester

(E)-7-[7-sec-Butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-5-hydroxy-3-oxo-hept-6-enoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
4: (i-Bu)2AlH / tetrahydrofuran; toluene / 0.5 h
5: MnO2 / benzene / 2 h / Heating
6: tetrahydrofuran
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

Sodium; (E)-(3S,5R)-7-[7-sec-butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate

Sodium; (E)-(3S,5R)-7-[7-sec-butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 1.) diisopropylamine, n-BuLi / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, RT, overnight
2: 1.) Et3N, 2.) aq. HCl / 1.) EtOH, from RT to reflux, 2.) THF, reflux, 4 h
3: NaH / tetrahydrofuran / Ambient temperature
4: (i-Bu)2AlH / tetrahydrofuran; toluene / 0.5 h
5: MnO2 / benzene / 2 h / Heating
6: tetrahydrofuran
7: 1.) Et3B, air, 2.) NaBH4 / 1.) MeOH, THF, 2 h, 2.) MeOH, THF, from -78 deg C to RT, overnight
8: aq. NaOH / methanol / 1 h / 0 - 20 °C
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

sulfuric acid
7664-93-9

sulfuric acid

hexahydro-3-(1-methylpropyl)-1H-azepin-2-one
1133438-62-6

hexahydro-3-(1-methylpropyl)-1H-azepin-2-one

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

ethyl 2-sec.butyl-cyclohexylideneacetate
85120-27-0

ethyl 2-sec.butyl-cyclohexylideneacetate

2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

naphthalene-1,8-diamine
479-27-6

naphthalene-1,8-diamine

C45H50N4O3

C45H50N4O3

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / propan-1-ol / 2 h / Reflux
2: propan-1-ol; toluene / 2 h / Reflux
View Scheme
2-sec-butylcyclohexanone
14765-30-1

2-sec-butylcyclohexanone

C14H22O3

C14H22O3

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium ethanolate / ethanol / 12 h / Reflux
2: hydrogenchloride / water / 2 h / 60 °C
View Scheme
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