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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Diethylzinc Manufacturer/High quality/Best price/In stock

Cas:557-20-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

DIMETHYLZINC Basic information Product Name: DIMETHYLZINC Synonyms: (CH3)2Zn;dimethyl-zin;methylzinc;Zinc, dimethyl-;zincmethyl;DIMETHYLZINC;Dimethylzinc solution;D

DIMETHYLZINC

Cas:557-20-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Diethylzinc

Cas:557-20-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Diethyl zinc

Cas:557-20-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Two ethyl zinc

Cas:557-20-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Diethylzinc, elec. gr., 99.9995%

Cas:557-20-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Diethylzinc

Cas:557-20-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Diethylzinc

Cas:557-20-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:Clear colorless solution Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used for the preparation of PEO catalyst Tran

Diethylzinc

Cas:557-20-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

557-20-0

Cas:557-20-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Diethylzinc Manufacturer/High quality/Best price/In stock

Cas:557-20-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Zinc, diethyl-CAS NO.: 557-20-0

Cas:557-20-0

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Zinc, diethyl-

Cas:557-20-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Diethylzinc

Cas:557-20-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 557-20-0 with competitive price

Cas:557-20-0

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Zinc, diethyl-

Cas:557-20-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

low price and high purity Application:ALD related industries,medicine and electronic materials

Diethylzinc DEZ

Cas:557-20-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Diethylzinc Application:Diethylzinc

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

we produce and sell good chemicals around the world.Appearance:white power Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:SEA OR AIR Port:China Main Po

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SAGECHEM LIMITED

557-20-0 Application:intermediate

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

DiethylzincAppearance:colorless transparent liquid Storage:0-6°C Package:500ml bottle, 30L steel cylinder, 300-500L storage tank. Application:Rieke and Organozinc Reagents Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amo

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

二乙基锌

Cas:557-20-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beantown Chemical

in stock Application:557-20-0

Diethylzinc solution, 15 wt. % in hexane

Cas:557-20-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HWRK Chem

in store Package:500ml Application:Organic Chemicals

Diethylzinc

Cas:557-20-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#557-20-0;CAT#A830770

Cas:557-20-0

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

triethylaluminum
97-93-8

triethylaluminum

zinc(II) chloride
7646-85-7

zinc(II) chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al (Et3Al/ZnCl2 2.2) dropped into flask over 10 min at room temp., stirred and heated at 100°C for 1 hed forfurther 20 min; distd.; NMR;86%
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al (Et3Al/ZnCl2 2.4) dropped into flask over 10 min at room temp., stirred and heated at 100°C for 1 hed forfurther 20 min; distd.; NMR;85.2%
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al (Et3Al/ZnCl2 2.6) dropped into flask over 10 min at room temp., stirred and heated at 100°C for 1 hed forfurther 20 min; distd.; NMR;81.1%
ethyl bromide
74-96-4

ethyl bromide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With copper(l) iodide; ethylzinc bromide In neat (no solvent) CuI, Zn were placed in reactor, evacuated for 10 min, filled with Ar, ligand and EtZnBr were added, heated to 38-40°C for 4.5 h, cooled to room temp.; vac. distilled;82%
triethyl-alane; compound with diethyl ether
13824-25-4, 14002-28-9

triethyl-alane; compound with diethyl ether

zinc(II) chloride
7646-85-7

zinc(II) chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al*Et2O (Et3Al*Et2O/ZnCl2 2.6) dropped intoflask over 10 min at room temp., stirred and heated at 100°C for1 hed for further 20 min; distd.; NMR;82%
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al*Et2O (Et3Al*Et2O/ZnCl2 2.2) dropped intoflask over 10 min at room temp., stirred and heated at 100°C for1 hed for further 20 min; distd.; NMR;80%
In neat (no solvent) Sonication; (N2), ZnCl2 introduced into a flask connected to a condenser containingalcohol at -20°C, Et3Al*Et2O (Et3Al*Et2O/ZnCl2 2.4) dropped intoflask over 10 min at room temp., stirred and heated at 100°C for1 hed for further 20 min; distd.; NMR;80.5%
ethyllithium
811-49-4

ethyllithium

zinc(II) chloride
7646-85-7

zinc(II) chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether at -10 - -5℃; for 10h; Large scale;81%
In not given treatment of (ethyl)Li with 0.5 equiv. of ZnCl2;
2-acetoxy-3,3-dimethyl-but-1-ene
3840-71-9

2-acetoxy-3,3-dimethyl-but-1-ene

EtZnOMe
15860-82-9

EtZnOMe

zinc pivaloylacetonate EtZnOMe complex

zinc pivaloylacetonate EtZnOMe complex

B

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In benzene byproducts: methyl acetate; under N2, soln. of EtZnOMe and CH3COOC(t-Bu)CH2 in C6H6 slowly heated to 60°C for 1 h; volatiles (methyl acetate, Et2Zn) removed, residue dissolved in pentane, cooled to -30°C;A 20%
B n/a
ethyl bromide
74-96-4

ethyl bromide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With coppered zinc
ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

ethyl zinc iodide

ethyl zinc iodide

diethylzinc
557-20-0

diethylzinc

ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With zinc(II) chloride
ethyl-isobutyl zinc
15106-84-0

ethyl-isobutyl zinc

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
at 25℃; Geschwindikeit der Umlagerung;
diethylmercury
627-44-1

diethylmercury

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With zinc at 100℃;
ethyl bromide
74-96-4

ethyl bromide

ethyl iodide
75-03-6

ethyl iodide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With coppered zinc
With zinc copper
ethyl iodide
75-03-6

ethyl iodide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With zinc ueber mehrere Stufen;
With zinc at 150 - 160℃;
With diethyl ether; zinc at 130℃; Destillation des Reaktionsproduktes;
diethyl ether
60-29-7

diethyl ether

ethylmagnesium bromide

ethylmagnesium bromide

ethylzinc iodide
999-75-7

ethylzinc iodide

diethylzinc
557-20-0

diethylzinc

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

ethylzinc iodide
999-75-7

ethylzinc iodide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With diethyl ether
ethyl radical
2025-56-1

ethyl radical

zinc

zinc

diethylzinc
557-20-0

diethylzinc

ethyl-radicals

ethyl-radicals

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With zinc
diethylmercury
627-44-1

diethylmercury

zinc

zinc

A

diethylzinc
557-20-0

diethylzinc

B

mercury

mercury

Conditions
ConditionsYield
at 100℃; aehnlich wirken Cadmium und Wismut;
ethyl sodium ; compound with diethyl zinc

ethyl sodium ; compound with diethyl zinc

mercury

mercury

zinc

zinc

A

diethylzinc
557-20-0

diethylzinc

B

sodium amalgam

sodium amalgam

ethyl zinc iodide

ethyl zinc iodide

A

diethylzinc
557-20-0

diethylzinc

B

zinc iodide

zinc iodide

Conditions
ConditionsYield
bei der Destillation in CO2-Strom;
ethyl iodide
75-03-6

ethyl iodide

A

diethylzinc
557-20-0

diethylzinc

B

ZnI2

ZnI2

Conditions
ConditionsYield
With zinc entsteht zunaechst Aethylzinkjodid, welches durch Destillation zersetzt;
ethyl iodide
75-03-6

ethyl iodide

A

diethylzinc
557-20-0

diethylzinc

B

zinc(II) iodide

zinc(II) iodide

Conditions
ConditionsYield
ethyl iodide, heated with granulated Zn and Zn dust at 80 up to 96°C, is forming ZnEt2 and ZnI2;;
{(ZnEt)2((2-(6-methyl)pyridyl)trimethylsilylamido)2}

{(ZnEt)2((2-(6-methyl)pyridyl)trimethylsilylamido)2}

A

{Zn((2-(6-methyl)pyridyl)trimethylsilylamido)2}

{Zn((2-(6-methyl)pyridyl)trimethylsilylamido)2}

B

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In neat (no solvent) Ar-atmosphere; 134°C, 0.10 torr (attempted sublimation);
Zn(C2H5)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C2H5)(C9H23N3)C5H(C6H5)4

Zn(C2H5)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C2H5)(C9H23N3)C5H(C6H5)4

dineopentylzinc
54773-23-8

dineopentylzinc

A

Zn(C5H11)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C5H11)(C9H23N3)C5H(C6H5)4

Zn(C5H11)(C9H23N3)(1+)*C5H(C6H5)4(1-)=Zn(C5H11)(C9H23N3)C5H(C6H5)4

B

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In benzene-d6 Kinetics; stirred for a few min, left standing in NMR tube at 22°C for 1 h; reversible reaction; not isolated; (1)H NMR spectral data;
ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

zinc dibromide

zinc dibromide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
Stage #1: zinc dibromide With sodium methylate In diethyl ether at 0 - 20℃; for 0.416667 - 0.583333h;
Stage #2: ethylmagnesium chloride In diethyl ether at 0 - 20℃; for 2.08333 - 2.16667h; Product distribution / selectivity;
ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

zinc dimethoxide
1184-55-0

zinc dimethoxide

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether Product distribution / selectivity;
Stage #1: zinc dimethoxide With sodium methylate In diethyl ether at 0 - 20℃; for 0.166667 - 0.5h;
Stage #2: ethylmagnesium bromide In diethyl ether at 0 - 20℃; for 2.08333 - 2.16667h; Product distribution / selectivity;
Stage #1: zinc dimethoxide With sodium benzoate In diethyl ether at 0 - 20℃; for 0.166667 - 0.5h;
Stage #2: ethylmagnesium bromide In diethyl ether at 0 - 20℃; for 2.08333 - 2.16667h; Product distribution / selectivity;
zinc diacrylate

zinc diacrylate

ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether Product distribution / selectivity;
ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

zinc(II) chloride
7646-85-7

zinc(II) chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether Product distribution / selectivity;
Stage #1: zinc(II) chloride With sodium methylate In diethyl ether at 0 - 20℃; for 0.416667 - 0.583333h;
Stage #2: ethylmagnesium chloride In diethyl ether at 0 - 20℃; for 2.08333 - 2.16667h; Product distribution / selectivity;
zinc diacetate
557-34-6

zinc diacetate

ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether Product distribution / selectivity;
ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

zinc benzoate
553-72-0

zinc benzoate

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
In diethyl ether Product distribution / selectivity;
cyclohexenone
930-68-7

cyclohexenone

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With copper(l) iodide; C19H19N2O2P In dichloromethane at -20℃; for 12h;100%
With N-benzylbenzenesulfonamide In toluene at 0℃; for 1h;99%
copper(I) 2-[(R)-Me2NCH2]-5-(Me3Si)-benzenethiolate In diethyl ether; hexane at -20℃; for 4h; Michael addition;99%
2-ethoxylbenzaldehyde
613-69-4

2-ethoxylbenzaldehyde

diethylzinc
557-20-0

diethylzinc

A

(R)-1-(2-ethoxyphenyl)-1-propanol
105836-16-6

(R)-1-(2-ethoxyphenyl)-1-propanol

B

(S)-1-(2-ethoxyphenyl)-1-propanol
124176-00-7

(S)-1-(2-ethoxyphenyl)-1-propanol

Conditions
ConditionsYield
Zn(II) complex with chiral Lewis acid-Lewis base ligand In toluene at 20℃; for 3h;A n/a
B 100%
With Quinine In toluene Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With N-ethyl (3S)-3-diphenylhydroxymethyl-2-azabicyclo<2.2.2>octane In hexane; toluene for 7h; Ambient temperature; Yield given. Yields of byproduct given;
diethylzinc
557-20-0

diethylzinc

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

(S)-1-(4-methylphenyl)propan-1-ol
25574-04-3, 112777-65-8, 138809-38-8, 73854-03-2

(S)-1-(4-methylphenyl)propan-1-ol

Conditions
ConditionsYield
(1S)-1-(9-piperidylfluoren-9-yl)ethanol In hexane; toluene at 0℃; for 4h; Addition;100%
Stage #1: diethylzinc In toluene at 0℃; for 0.5h;
Stage #2: 4-methyl-benzaldehyde In toluene at 0 - 20℃; for 48h; Reagent/catalyst; enantioselective reaction;
99%
Stage #1: diethylzinc; 4-methyl-benzaldehyde With diphenyl-((S)-1-((S)-1-phenylethyl)aziridin-2-yl)-methanol In hexane; toluene at 0 - 25℃; for 48.5h; Inert atmosphere;
Stage #2: With ammonium chloride In hexane; water; toluene Saturated solution; optical yield given as %ee; enantioselective reaction;
98%
diethylzinc
557-20-0

diethylzinc

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

(R)-1-(4-chlorophenyl)-1-propanol
110611-21-7

(R)-1-(4-chlorophenyl)-1-propanol

Conditions
ConditionsYield
Stage #1: diethylzinc With (Ra)-3,3'-bis(diphenylphosphinoyl)-BINOL In tetrahydrofuran; toluene at -78℃; for 0.5h;
Stage #2: 4-chlorobenzaldehyde In tetrahydrofuran; toluene at -20℃; for 24h;
100%
(1R,2S)-(-)-1-phenyl-2-piperidinopropane-1-thiol In toluene at 0℃; for 12h;99%
With 1,1-diethyl-3-(3'-indolyl)-(2S)-(N-methyl-N-3'',3''-dimethylbutylamino)-1-propanol In hexane; toluene at 20℃; for 96h; Addition;99%
diethylzinc
557-20-0

diethylzinc

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

(S)-1-(4-chlorophenyl)-1-propanol
73890-73-0

(S)-1-(4-chlorophenyl)-1-propanol

Conditions
ConditionsYield
R,S-1,2-disubstituted ferrocenyl amino alcohol 8o In hexane for 1h; Ambient temperature;100%
With (R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;99%
With 2-tert-butyl-6-((2S,4S,5R)-3,4-dimethyl-5-phenyloxazolidyn-2-yl)-4-methylphenol In hexane; toluene at 20℃; for 72h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
diethylzinc
557-20-0

diethylzinc

1-naphthaldehyde
66-77-3

1-naphthaldehyde

Conditions
ConditionsYield
(1R,2S)-(-)-1-phenyl-2-piperidinopropane-1-thiol In toluene at 0℃; for 12h;100%
Stage #1: diethylzinc; 1-naphthaldehyde With diphenyl-((R)-1-((S)-1-phenylethyl)aziridin-2-yl)-methanol In hexane; toluene at 0 - 25℃; for 48.5h; Inert atmosphere;
Stage #2: With ammonium chloride In hexane; water; toluene Saturated solution; optical yield given as %ee; enantioselective reaction;
99%
Stage #1: diethylzinc With (1R,3S)-1-benzyl-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-1,3-dihydro-2-benzofuran-1-ol In hexane; toluene at 0℃; for 0.0833333h;
Stage #2: 1-naphthaldehyde In hexane; toluene at 0℃; for 2h; Catalytic behavior; Reagent/catalyst; Temperature; enantioselective reaction;
99%
diethylzinc
557-20-0

diethylzinc

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenyl-1-propanol
1565-74-8

(R)-1-phenyl-1-propanol

Conditions
ConditionsYield
With P-1-(4',6'-dimethyl-2'-hydroxyphenyl)-2-(N,N-di-n-butylaminomethyl)naphthalene In hexane at 20℃; for 16h;100%
titanium(IV) isopropylate; 1,3,5-[(M)-2-(2-HOCH2-1-naphthyl)-3,5-Me2C6H2OCH2]3-benzene In hexane; dichloromethane at 40℃; for 16h;100%
With (1R,2R)-N,N'-bis[(2,4,6-trimethylphenyl)methylene]-1,2-cyclohexane-diamine; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane at -78 - -20℃; for 5h;100%
diethylzinc
557-20-0

diethylzinc

benzaldehyde
100-52-7

benzaldehyde

(S)-1-phenyl-1-propanol
613-87-6

(S)-1-phenyl-1-propanol

Conditions
ConditionsYield
(1S,2R)-(-)-2-(N,N-di-n-butylamino)-1-phenylpropan-1-ol In hexane 1.) r.t., 20 min; 2.) 0 deg C, 16 h;100%
With (R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;100%
Stage #1: diethylzinc; benzaldehyde With (1S,2R,3S,5S)-6,6-dimethyl-3-morpholinobicyclo[3.1.1]heptan-2-ol; (1R,2S,3R,5R)-6,6-dimethyl-3-morpholinobicyclo[3.1.1]heptan-2-ol In hexane at -15 - 0℃; for 18h; Inert atmosphere;
Stage #2: With water; ammonium chloride In hexane at 0℃; optical yield given as %ee; enantioselective reaction;
100%
diethylzinc
557-20-0

diethylzinc

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

(R)-1-(4'-methoxyphenyl)-1-propanol
105836-14-4

(R)-1-(4'-methoxyphenyl)-1-propanol

Conditions
ConditionsYield
With (1R,2R)-N,N'-bis[(2,4,6-trimethylphenyl)methylene]-1,2-cyclohexane-diamine; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane at -78 - -20℃; for 5h;100%
Stage #1: diethylzinc; 4-methoxy-benzaldehyde With (2R,3S,3aS,4aR,6R,8aS)-2-isopropyl-6,9,9-trimethyl-3-phenyldecahydro-4aH-pyrrolo[2,1-b][1,3]benzoxazin-3-ol In hexane; toluene at 20℃; Inert atmosphere;
Stage #2: With ammonium chloride In hexane; water; toluene optical yield given as %ee; enantioselective reaction;
99%
Stage #1: diethylzinc With polystyrene supported nickel(II) complexes derived from α-amino amides In toluene at 0℃; for 0.166667h; Green chemistry;
Stage #2: 4-methoxy-benzaldehyde In toluene at 0℃; for 36h; Inert atmosphere; Green chemistry; enantioselective reaction;
98%
diethylzinc
557-20-0

diethylzinc

ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

(-)-(S)-1-(o-methoxyphenyl)propanol
7452-01-9, 105836-13-3, 123879-92-5, 114389-71-8

(-)-(S)-1-(o-methoxyphenyl)propanol

Conditions
ConditionsYield
(1S,2R)-(-)-2-(N,N-di-n-butylamino)-1-phenylpropan-1-ol In hexane 1.) r.t., 20 min; 2.) 0 deg C, 16 h;100%
Stage #1: diethylzinc; ortho-anisaldehyde With diphenyl-((S)-1-((S)-1-phenylethyl)aziridin-2-yl)-methanol In hexane; toluene at 0 - 25℃; for 48.5h; Inert atmosphere;
Stage #2: With ammonium chloride In hexane; water; toluene Saturated solution; optical yield given as %ee; enantioselective reaction;
99%
With dibutylamino thioacetate derivative of (+)-norephedrine In hexane at 0 - 20℃; for 6h;97%
nitrostyrene
5153-67-3

nitrostyrene

diethylzinc
557-20-0

diethylzinc

(1-nitromethyl-propyl)-benzene
119880-63-6, 7796-78-3

(1-nitromethyl-propyl)-benzene

Conditions
ConditionsYield
With chiral (OCHPhCHMeN(i-Pr))PNMe2; copper(I) triflate In hexane; toluene at -30℃; for 3h; Addition;100%
copper(I) 2-(Me2NCH2)-3-(Me3Si)-naphthalene-1-thiolate In diethyl ether; hexane at -20℃; for 4h; Michael addition;98%
With magnesium bromide In diethyl ether for 1h; Ambient temperature;92%
diethylzinc
557-20-0

diethylzinc

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

1-(4-methoxyphenyl)-1-propanol
5349-60-0

1-(4-methoxyphenyl)-1-propanol

Conditions
ConditionsYield
With (R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;100%
With titanium(IV) isopropylate; (1R,2R)-(+)-1,2-(3,3',5,5'-tetrachloro-2,2'-dihydroxydibenzosulfonamido)cyclohexane In hexane at -23℃;98%
With (-)-η5-(pentamethylcyclopentadienyl)-η5-(2-((2-hydroxy-2,2-diphenylethyl)oxymethyl)pyrrolyl)iron In toluene Ambient temperature;94%
2-ethoxylbenzaldehyde
613-69-4

2-ethoxylbenzaldehyde

diethylzinc
557-20-0

diethylzinc

(R)-1-(2-ethoxyphenyl)-1-propanol
105836-16-6

(R)-1-(2-ethoxyphenyl)-1-propanol

Conditions
ConditionsYield
With (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-methanethiol In hexane; toluene for 7h; Ambient temperature;100%
cyclohexenone
930-68-7

cyclohexenone

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With copper(I) thiophene-2-carboxylate; chiral biphenol P-N ligand In diethyl ether100%
With copper(II) bis(trifluoromethanesulfonate); (11aR)-(+)-10,11,12,13-tetrahydrodiindeno[7,1-de:1', 7'-fg][1,3,2]dioxaphosphocin-5-bis[(R)-1-phenylethyl]amine In toluene at 25℃; for 2h; Product distribution; Further Variations:; Reagents; Solvents; Temperatures;99%
With copper(I) trifluoromethanesulfonate benzene; bis[(S,S)-H8-BINOL][(S)-BINOL]diphosphite In diethyl ether at -30℃; for 15h;99%
diethylzinc
557-20-0

diethylzinc

Acetic acid (2R,4S,6R)-2-tert-butyl-6-hexyl-[1,3]dioxan-4-yl ester

Acetic acid (2R,4S,6R)-2-tert-butyl-6-hexyl-[1,3]dioxan-4-yl ester

(2R*,4S*,6S*)-2-tert-butyl-4-ethyl-6-hexyl-1,3-dioxane

(2R*,4S*,6S*)-2-tert-butyl-4-ethyl-6-hexyl-1,3-dioxane

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In diethyl ether at -78℃; for 1h;100%
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at -78℃; for 0.6h;90%
diethylzinc
557-20-0

diethylzinc

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

(S)-1-(4-fluorophenyl)propanol

(S)-1-(4-fluorophenyl)propanol

Conditions
ConditionsYield
(1S)-1-(9-piperidylfluoren-9-yl)ethanol In hexane; toluene at 0℃; for 4h; Addition;100%
Stage #1: diethylzinc In toluene at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 4-fluorobenzaldehyde In toluene at 0℃; for 6h; Inert atmosphere;
Stage #3: With ammonium chloride In water; toluene at 0℃; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
92%
Stage #1: diethylzinc With (Sa)-1-[2-diphenylhydroxymethyl-6-(trifluoromethyl)phenyl]-2-(1-pyrrolidinomethyl)-1H-pyrrole In hexane at 20℃; for 1h; Inert atmosphere;
Stage #2: 4-fluorobenzaldehyde In hexane at 0℃; for 16h; Inert atmosphere; enantioselective reaction;
91%
diethylzinc
557-20-0

diethylzinc

3-Chlorobenzaldehyde
587-04-2

3-Chlorobenzaldehyde

(S)-1-(3-chlorophenyl)propan-1-ol
172748-80-0

(S)-1-(3-chlorophenyl)propan-1-ol

Conditions
ConditionsYield
(1S)-1-(9-piperidylfluoren-9-yl)ethanol In hexane; toluene at 0℃; for 4h; Addition;100%
Stage #1: diethylzinc With 2,2'-(propane-2,2-diyl)bis(6,6-dimethyl-5,6,7,8-tetrahydro-5,7-methanoquinoline-8,2-diyl)bis(diphenylmethanol) In toluene at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: m-Chlorobenzaldehyde In toluene at -20℃; for 57h; Inert atmosphere; enantioselective reaction;
99%
Stage #1: diethylzinc With (1'R,2R,3R)-1-(1'-phenylethyl)-2-phenyl-3-hydroxyazetidine In toluene at 20℃; for 0.333333h;
Stage #2: m-Chlorobenzaldehyde In toluene at 20℃; for 29h; Inert atmosphere; enantioselective reaction;
98%
diethyl ethylidenemalonate
1462-12-0

diethyl ethylidenemalonate

diethylzinc
557-20-0

diethylzinc

sec-butyl-malonic acid diethyl ester
83-27-2

sec-butyl-malonic acid diethyl ester

Conditions
ConditionsYield
With copper(II) bis(trifluoromethanesulfonate); (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In hexane; toluene at 0℃; for 3h;100%
With copper(II) bis(trifluoromethanesulfonate); triethyl phosphite In hexane; toluene -20 deg C and 20 min, 0 deg C;95%
diethylzinc
557-20-0

diethylzinc

1,3-diphenyl-propen-3-one
614-47-1

1,3-diphenyl-propen-3-one

Conditions
ConditionsYield
With copper(I) trifluoromethanesulfonate benzene complex In diethyl ether; hexane at -20℃; for 22h; Michael addition;100%
With copper(II) choride dihydrate; (o-hydroxyphenyl)diphenylphosphine In tetrahydrofuran at -20℃; for 2h;98%
With 3,7-bis[(1'S,2'R)-2'-OH-1'-Me-2'-PhEt]-3,7-diaza-C7H12N2; bis(acetylacetonate)nickel(II) In hexane; acetonitrile at -30℃; for 16h; Addition;96%
diethylzinc
557-20-0

diethylzinc

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

(1S)-1-(3-methoxyphenyl)propan-1-ol
134677-28-4

(1S)-1-(3-methoxyphenyl)propan-1-ol

Conditions
ConditionsYield
(1S)-1-(9-piperidylfluoren-9-yl)ethanol In hexane; toluene at 0℃; for 4h; Addition;100%
Stage #1: diethylzinc In toluene at 0℃; for 0.5h;
Stage #2: 3-methoxy-benzaldehyde In toluene at 0 - 20℃; for 48h; Reagent/catalyst; enantioselective reaction;
99%
With (3S,4S)-2,2-dimethyl-4-[N-(9'-phenylfluoren-9'-yl)amino]pentan-3-ol In hexane; toluene at 18℃; for 1h; Addition;97%
diethylzinc
557-20-0

diethylzinc

m-tolyl aldehyde
620-23-5

m-tolyl aldehyde

(S)-1-(3-methylphenyl)propan-1-ol
213267-92-6

(S)-1-(3-methylphenyl)propan-1-ol

Conditions
ConditionsYield
(1S)-1-(9-piperidylfluoren-9-yl)ethanol In hexane; toluene at 0℃; for 4h; Addition;100%
Stage #1: diethylzinc With 2,2'-(propane-2,2-diyl)bis(6,6-dimethyl-5,6,7,8-tetrahydro-5,7-methanoquinoline-8,2-diyl)bis(diphenylmethanol) In toluene at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: m-tolyl aldehyde In toluene at -20℃; for 57h; Inert atmosphere; enantioselective reaction;
95%
Stage #1: m-tolyl aldehyde With (E,4R,5S)-N-allyl-5-cyclohexyl-5-hydroxy-4-morpholinopent-2-enamide In toluene at 20℃; for 0.333333h; Inert atmosphere;
Stage #2: diethylzinc In hexane; toluene at 20℃; for 6h; Reagent/catalyst; Inert atmosphere; enantioselective reaction;
95%
4-tert-Butylbenzaldehyde
939-97-9

4-tert-Butylbenzaldehyde

diethylzinc
557-20-0

diethylzinc

1-(4-tert-butylphenyl)propan-1-ol
127896-25-7

1-(4-tert-butylphenyl)propan-1-ol

Conditions
ConditionsYield
With (R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;100%
With (1R,2R)-N,N'-bis[(2,4,6-trimethylphenyl)methylene]-1,2-cyclohexane-diamine; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane at -78 - -20℃; for 5h;100%
With titanium(IV) isopropylate at 80℃; for 1h; Time; Inert atmosphere;60 %Chromat.
With magnesium chloride at 80℃; for 0.5h; Reagent/catalyst; Inert atmosphere;24.2 %Chromat.
diethylzinc
557-20-0

diethylzinc

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

1-(3-methoxyphenyl)propanol
52956-27-1

1-(3-methoxyphenyl)propanol

Conditions
ConditionsYield
With (R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;100%
With (1R,2R)-N,N'-bis[(2,4,6-trimethylphenyl)methylene]-1,2-cyclohexane-diamine; (R)-(+)-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol In hexane; dichloromethane at -78 - -20℃; for 5h;100%
Stage #1: diethylzinc With titanium(IV) isopropylate; (1R,2R)-1,2-bis(3,5-dibromophenyl)ethane-1,2-diol In hexane; dichloromethane at 25℃; for 0.333333h; Inert atmosphere;
Stage #2: 3-methoxy-benzaldehyde In hexane; dichloromethane at 0℃; for 24h; Reagent/catalyst; Inert atmosphere;
53%
diethylzinc
557-20-0

diethylzinc

β-nitroacroleine dimethyl acetal
300720-95-0

β-nitroacroleine dimethyl acetal

1,1-dimethoxy-2-nitromethyl-butane

1,1-dimethoxy-2-nitromethyl-butane

Conditions
ConditionsYield
With chiral PhP(OC(2-naphth)2CH(OCMe2O)CHC(2-naphth)22O); copper(II) bis(trifluoromethanesulfonate) In toluene at -30℃; Addition;100%
With racemic 1,1'-bi(2-naphthol) based phosphoramidite; copper(II) bis(trifluoromethanesulfonate) In hexane; toluene at -45℃; for 3h;64%
cyclohexenone
930-68-7

cyclohexenone

diethylzinc
557-20-0

diethylzinc

Conditions
ConditionsYield
With copper(I) thiophene-2-carboxylate; chiral binapthol P-N ligand In diethyl ether100%
With copper(I) bromide dimethylsulfide complex; 2-(diphenylphosphanyl)benzoyl-L-valyl-L-valine methyl ester In diethyl ether at -30℃; for 2h; Product distribution; Further Variations:; Temperatures; Reagents; Solvents;98%
With copper(I) trifluoromethanesulfonate benzene; [(2-PPh2)C6H4CH]-Val-Phe-NH-Bu In toluene at -30℃; for 6h;98%
diethylzinc
557-20-0

diethylzinc

m-tolyl aldehyde
620-23-5

m-tolyl aldehyde

(R)-1-(3-tolyl)-1-propanol
32019-31-1, 112777-68-1

(R)-1-(3-tolyl)-1-propanol

Conditions
ConditionsYield
Stage #1: diethylzinc; m-tolyl aldehyde With (1S,2R,3S,5S)-6,6-dimethyl-2-morpholinobicyclo[3.1.1]heptan-3-ol; (1R,2S,3R,5R)-6,6-dimethyl-2-morpholinobicyclo[3.1.1]heptan-3-ol In hexane at -15 - 0℃; for 18h; Inert atmosphere;
Stage #2: With water; ammonium chloride In hexane at 0℃; optical yield given as %ee; enantioselective reaction;
100%
With 4-methyl-N-{[(1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl]methyl}benzenesulfonamide In hexane at 0℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;97%
With titanium(IV) isopropylate In dichloromethane at 0℃;96%
2-Cyclohepten-1-one
1121-66-0

2-Cyclohepten-1-one

diethylzinc
557-20-0

diethylzinc

(R)-3-ethylcycloheptan-1-one

(R)-3-ethylcycloheptan-1-one

Conditions
ConditionsYield
With chiral binapthol P-N ligand; copper(II) bis(trifluoromethanesulfonate) In toluene100%
With n-butyllithium; C21H29N2O(1+)*F6P(1-); copper(II) bis(trifluoromethanesulfonate) In diethyl ether at 20℃; for 1h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
With copper(I) trifluoromethanesulfonate benzene; [(2-PPh2)C6H4CH]-Val-Phe-NH-Bu In toluene at -30℃; for 12h;98%
diethylzinc
557-20-0

diethylzinc

acetic anhydride
108-24-7

acetic anhydride

isobutyraldehyde
78-84-2

isobutyraldehyde

2-methyl-3-pentyl acetate
35897-16-6

2-methyl-3-pentyl acetate

Conditions
ConditionsYield
Stage #1: diethylzinc; isobutyraldehyde With (Rp,S)-5-[C6H11-CH(Me)-N=C(Me)]-4-OH-[2.2]paracyclophane In hexane at 0℃; for 14h;
Stage #2: acetic anhydride In hexane at 20℃; for 24h; Further stages.;
100%
diethylzinc
557-20-0

diethylzinc

O-methyl S-ethyl thioladipate
73636-31-4

O-methyl S-ethyl thioladipate

Methyl 6-oxooctanoate
2955-61-5

Methyl 6-oxooctanoate

Conditions
ConditionsYield
With bromine; N,N-dimethyl-formamide; zinc; palladium on activated charcoal In tetrahydrofuran; toluene at 20℃; for 17h; Fukuyama coupling reaction;100%
With bromine; N,N-dimethyl-formamide; zinc; palladium on activated charcoal In tetrahydrofuran; toluene at 20℃; for 17h; Fukuyama coupling reaction;100%
3,4 difluorobenzaldehyde
34036-07-2

3,4 difluorobenzaldehyde

diethylzinc
557-20-0

diethylzinc

(S)-1-(3,4-Difluoro-phenyl)-propan-1-ol
847448-30-0

(S)-1-(3,4-Difluoro-phenyl)-propan-1-ol

Conditions
ConditionsYield
With titanium(IV) isopropylate; N,N’-(1R,2R)-cyclohexane-1,2-diylbis(1,1,1-trifluoromethanesulfonamide) In toluene at -78℃;100%
Stage #1: diethylzinc With titanium(IV) isopropylate; C48H34O4 In diethyl ether; hexane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 3,4 difluorobenzaldehyde In diethyl ether; hexane at 20℃; for 5h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
92%
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