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inquiry(1S,2S)-(+)-TRANS-1-AMINO-2-INDANOL CAS:163061-74-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qua
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inquiryMelting Point:142-146 °C Boiling Point:290 °C at 760 mmHg PKA:14.79±0.40(Predicted) Flash Point:129.2 °C PSA:46.25000 Density:1.212 g/cm3 LogP:1.30370 XLogP3:0.2 Hydrogen Bond Donor Count:2 Hydrogen Bond Acceptor
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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inquiryLower price, higher purity,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, s
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(1S,2S)-(+)-trans-1-Amino-2-indanol Application:(1S,2S)-(+)-trans-1-Amino-2-indanol
(1S,2S)-(+)-TRANS-1-AMINO-2-INDANOLCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
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inquiry(1S,2S)-(+)-trans-1-Amino-2-indanolAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airp
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inquirytert-butyl ((1S,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamate
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With hydrogenchloride In methanol; water at 0 - 20℃; Inert atmosphere; | 100% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With 5%-palladium/activated carbon; hydrogen In methanol at 60 - 65℃; under 6000.6 Torr; | 93% |
(1aR,6aS)-6,6a-dihydro-1aH-indeno[1,2-b]oxirene
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With ammonium hydroxide | 81% |
Multi-step reaction with 2 steps 1: 70 percent / NaN3 2: 60 percent / LiAlH4 View Scheme | |
With ammonia In water at 20℃; for 5h; Inert atmosphere; | 0.57 g |
trans-2-bromo-2,3-dihydro-1H-inden-1-ol
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With ammonia In water at 0℃; for 24.5h; | 69% |
(1S,2S)-1-azido-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride | 60% |
trans-1-aminoindan-2-ol
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
di-tert-butyl dicarbonate
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
tert-butyl ((1S,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamate
Conditions | Yield |
---|---|
With sodium carbonate In tetrahydrofuran; water at 0 - 20℃; for 3h; | 100% |
With sodium carbonate In tetrahydrofuran; water at 0 - 20℃; for 3h; | 100% |
With triethylamine In methanol at 20℃; for 48h; | 98% |
3,5-bistrifluoromethylphenylisothiocyanate
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
1-[3,5-bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]thiourea
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 18h; | 100% |
formaldehyd
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-dimethylamino-2-indanol
Conditions | Yield |
---|---|
With formic acid In water at 95℃; Inert atmosphere; | 99% |
1-(tert-butoxycarbonyl)-L-proline
chloroformic acid ethyl ester
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With 4-methyl-morpholine In ethyl acetate | 99% |
3,5-di-tert-butyl-2-hydroxybenzaldehyde
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-((E)-(3,5-ditert-butyl-2-hydroxybenzylidene)amino)-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With acetic acid In ethanol Reflux; | 98% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
benzoyl chloride
N-((1S,2S)-2-Hydroxy-indan-1-yl)-benzamide
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 1h; Ambient temperature; | 91% |
L-N-Boc-Ala
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
C17H24N2O4
Conditions | Yield |
---|---|
Stage #1: L-N-Boc-Ala With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; for 0.0833333h; Inert atmosphere; Stage #2: (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere; | 86% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; | 85% |
ethyl 2-(anthracen-9-ylamino)-2-oxoacetate
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
N-(9-anthryl)-N'-((1S,2S)-2-hydroxy-1-indanyl)oxalamide
Conditions | Yield |
---|---|
In dichloromethane for 20h; Reflux; | 84% |
1,5-dibromo-pentane
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-(piperidin-1-yl)-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In isopropyl alcohol at 80℃; for 48h; Sealed tube; | 75% |
With potassium carbonate; potassium iodide In isopropyl alcohol at 80℃; for 48h; sealed; | 75% |
With potassium carbonate; potassium iodide In isopropyl alcohol at 80℃; for 48h; | 75% |
With potassium carbonate In ethanol at 75℃; for 24h; Inert atmosphere; | 71% |
formaldehyd
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
In water at 20℃; for 3h; pH=3; | 74% |
ortho-diphenylphosphinobenzoic acid
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
2-(diphenylphosphino)-N-((1S,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)benzamide
Conditions | Yield |
---|---|
Stage #1: ortho-diphenylphosphinobenzoic acid; (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 24h; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane; water Inert atmosphere; | 71% |
2,6-dichloro-N4,N8-dimethyl-pyrimido[5,4-d]pyrimidine-4,8-diamine
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
In butan-1-ol | 64% |
ethyl 2,3,4,5,6-pentamethylphenyloxamate
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
N-(2,3,4,5,6-pentamethylphenyl)-N′-((1S,2S)-2-hydroxy-1-indanyl)oxalamide
Conditions | Yield |
---|---|
In dichloromethane for 60h; Reflux; | 59% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
3α,12α-dihydroxy-5β-cholan-24-oic acid 2,5-dioxopyrrolidin-1-yl ester
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 20℃; | 55% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 2.5h; Cooling with ice; | 44% |
ortho-diphenylphosphinobenzoic acid
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-(2-(diphenylphosphino)benzamido)-2,3-dihydro-1H-inden-2-yl 2-(diphenylphosphino)benzoate
Conditions | Yield |
---|---|
Stage #1: ortho-diphenylphosphinobenzoic acid; (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 24h; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane; water Inert atmosphere; | 40% |
5-amino-4,6-dichloropyridimine
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(1S,2S)-1-(5-amino-6-chloropyrimidin-4-ylamino)-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
With triethylamine In butan-1-ol for 24h; Inert atmosphere; Reflux; | 38% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
1-{3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl}piperidin-4-one
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In methanol at 20℃; for 4h; reductive amination; | 37% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
Conditions | Yield |
---|---|
Stage #1: 2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetaldehyde; (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol In methanol; dichloromethane for 2h; Stage #2: With sodium tris(acetoxy)borohydride In dichloromethane for 12h; | 33% |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
(S)-2-((1S,2S)-2-Hydroxy-indan-1-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester
Conditions | Yield |
---|---|
In tetrahydrofuran |
(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol
N-Benzyloxycarbonyl-L-proline
(S)-2-((1S,2S)-2-Hydroxy-indan-1-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester
Conditions | Yield |
---|---|
Stage #1: N-Benzyloxycarbonyl-L-proline With chloroformic acid ethyl ester; triethylamine In tetrahydrofuran at 0℃; for 0.75h; Stage #2: (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol In tetrahydrofuran for 3h; Heating; Further stages.; |
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