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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

gamma-Benzyl L-glutamate Manufacturer/High quality/Best price/In stock

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality L-Glutamic Acid 5- Benzyl Ester supplier in China

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:

5-Benzyl L-GlutaMate

Cas:1676-73-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply L-Glutamic Acid 5- Benzyl Ester

Cas:1676-73-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 1676-73-9 L-Glutamicacid, 5-(phenylmethyl) ester

Cas:1676-73-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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SICHUAN TONGSHENG AMINOACID CO.LTD

Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we have the best quality and price. Guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008,

L-Glutamic acid γ-benzyl ester

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

gamma-Benzyl L-glutamate

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-Glutamic acid 5-benzyl ester

Cas:1676-73-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Density: 1.2026 (rough estimate) Melting point: 181-182 ° C (lit.) Boiling point: 379.78 ° C (rough estimate) Specific rotation: 27.2 º (c=2, 1N HCL) Flash point: 224 ° C Steam pressure: 9.12E-09mmHg at 25 ° C Solubility: Acid Ac

gamma-Benzyl L-glutamate 1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 1676-73-9 with best price

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

H-L-Glu(oBzl)-OH

Cas:1676-73-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

gamma-Benzyl L-glutamateCAS1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name L-Glutamic acid γ-benzyl ester CAS 1676-73-9 MF C12H15NO4 MW 237.25 ENECS 216-826-1 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25KG/drum Application:Vitamins, Amino Acids a

Gamma-benzyl-L-glutamate CAS:1676-73-9

Cas:1676-73-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

L-Glutamic acid γ-benzyl ester manufacturer/supplier

Cas:1676-73-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

L-Glutamicacid, 5-(phenylmethyl) ester 1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply GAMMA-BENZYL-L-GLUTAMATE CAS 1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Animal Pharmaceuticals, gamma-Benzyl L-glutamate CAS:1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 148.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

gamma-Benzyl L-glutamate CAS:1676-73-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

gamma-Benzyl L-glutamate CAS:1676-73-9

Cas:1676-73-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Glutamicacid, 5-(phenylmethyl) ester

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

H-Glu(OBzl)-OH

Cas:1676-73-9

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

L-Glutamicacid, 5-(phenylmethyl) ester

Cas:1676-73-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name:gamma-Benzyl L-glutamate CAS No:1676-73-9 Appearance:White powder Assay:98% Appearance:White powder Storage:keep sealed and keep from direct light Package:According to client's requirements Application:Amino acid series products

high quality gamma-Benzyl L-glutamate manufacture

Cas:1676-73-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

H-L-Glu(oBzl)-OH

Cas:1676-73-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

L-GLUTAMICACID, 5-(PHENYLMETHYL) ESTER

Cas:1676-73-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

gamma-Benzyl L-glutamate

Cas:1676-73-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality L-Glutamic Acid 5- Benzyl Ester

Cas:1676-73-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

H-L-Glu(oBzl)-OH

Cas:1676-73-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:The goods in the body into sugar, as a precursor for synt

gamma-Benzyl L-glutamate

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

gamma-Benzyl L-glutamate,1676-73-9

Cas:1676-73-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Product Name:gamma-Benzyl L-glutamate CAS No:1676-7

gamma-Benzyl L-glutamate

Cas:1676-73-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Synthetic route

Z(OMe)-Glu(OBzl)-OH
23506-06-1

Z(OMe)-Glu(OBzl)-OH

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With methanesulfonic acid; 3-methyl-phenol In dichloromethane at 25℃; for 0.5h;100%
L-glutamic acid
56-86-0

L-glutamic acid

benzyl alcohol
100-51-6

benzyl alcohol

A

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

B

1-benzyl L-glutamate
13030-09-6

1-benzyl L-glutamate

Conditions
ConditionsYield
With copper dichloride at 60℃; for 2h; Catalytic behavior; Mechanism; Reagent/catalyst; Solvent; Temperature;A 95.31%
B n/a
L-glutamic acid
56-86-0

L-glutamic acid

benzyl alcohol
100-51-6

benzyl alcohol

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With tetrafluoroboric acid diethyl ether; sodium sulfate for 15h; Ambient temperature;94%
With tetrafluoroboric acid diethyl ether; sodium sulfate at 20℃; for 12h; Inert atmosphere;80%
Stage #1: L-glutamic acid; benzyl alcohol With methanesulfonic acid In toluene at 30 - 45℃; for 6h;
Stage #2: With ammonia In ethanol; water at 60℃; for 2h; pH=6.5 - 7;
77%
dibenzyl L-glutamate
2768-50-5

dibenzyl L-glutamate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With water In acetone at 37℃; for 4h; Alcalase, pH 8.2;85%
In ethanol; water at 25℃; for 3h; pronase (E C 3.4.24.4.), pH 7.2;72%
(i) TsOH, (ii) CuSO4*5H2O, aq. NaOH, EtOH, Na2H2edta; Multistep reaction;
Copper(II); (S)-2-amino-4-benzyloxycarbonyl-butyrate

Copper(II); (S)-2-amino-4-benzyloxycarbonyl-butyrate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With sodium sulfide In water at 25 - 30℃; for 0.166667h;84%
γ-benzyl L-glutamate methanesulphonate

γ-benzyl L-glutamate methanesulphonate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With ammonia In water at 13 - 15℃; for 2h; pH=5.9 - 6.3;81%
L-glutamic acid
56-86-0

L-glutamic acid

benzyl bromide
100-39-0

benzyl bromide

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With copper70%
Yield given. Multistep reaction;
Oδ-Bzl-L-Glu/copper complex

Oδ-Bzl-L-Glu/copper complex

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With N,N-Dibutyl-N'-(benzoyl)thioharnstoff In ethanol for 2h; Heating;60%
L-glutamic acid
56-86-0

L-glutamic acid

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

benzyl alcohol
100-51-6

benzyl alcohol

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
at 120℃; under 2 Torr;
L-glutamic acid
56-86-0

L-glutamic acid

benzenesulfonic acid
98-11-3

benzenesulfonic acid

benzyl alcohol
100-51-6

benzyl alcohol

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
at 100 - 105℃;
benzyl bromide
100-39-0

benzyl bromide

3-((S)-2,2-Diethyl-5-oxo-4,5-dihydro-3λ5,2λ5-[1,3,2]oxazaborol-4-yl)-propionic acid

3-((S)-2,2-Diethyl-5-oxo-4,5-dihydro-3λ5,2λ5-[1,3,2]oxazaborol-4-yl)-propionic acid

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With hydrogenchloride; N-cyclohexyl-cyclohexanamine 1) DMF, 60-70 degC, 5 min; 2) EtOAc; Yield given. Multistep reaction;
iodomethylbenzene
620-05-3

iodomethylbenzene

2C5H7NO4(2-)*Cu(2+)*2Na(1+)

2C5H7NO4(2-)*Cu(2+)*2Na(1+)

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide
L-glutamic acid dibenzyl ester 4-toluenesulfonate
2791-84-6

L-glutamic acid dibenzyl ester 4-toluenesulfonate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; water; copper(II) sulfate 1.) EtOH, 32 deg C, 60 min, 2.) EtOH, 100 deg C; Yield given; Multistep reaction;
L-glutamic acid
56-86-0

L-glutamic acid

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 72 percent / benzene / Heating
2: 1.) CuSO4*5H2O, H2O, 2.) EDTA, H2O / 1.) EtOH, 32 deg C, 60 min, 2.) EtOH, 100 deg C
View Scheme
toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

4-polystyryltriphenylmethyl-Phe-ODpm

4-polystyryltriphenylmethyl-Phe-ODpm

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 72 percent / benzene / Heating
2: 1.) CuSO4*5H2O, H2O, 2.) EDTA, H2O / 1.) EtOH, 32 deg C, 60 min, 2.) EtOH, 100 deg C
View Scheme
D-Glutamic acid
6893-26-1

D-Glutamic acid

benzyl alcohol
100-51-6

benzyl alcohol

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Conditions
ConditionsYield
With sulfuric acid at 70℃;
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

Boc-Glu(OBzl)-OH
13574-13-5

Boc-Glu(OBzl)-OH

Conditions
ConditionsYield
In 1,4-dioxane; water at 0℃;100%
In 1,4-dioxane; water at 0℃;100%
With triethylamine In N,N-dimethyl-formamide at 60℃; for 0.5h;98%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

L-glutamic acid
56-86-0

L-glutamic acid

Conditions
ConditionsYield
With dimethylsulfide; hydrogen fluoride; methoxybenzene at 0℃; for 1h; Product distribution; Rate constant; other concentration of reagents;100%
With dimethylsulfide; trifluorormethanesulfonic acid; 30 (v/v); trifluoroacetic acid at 0℃; for 4h; Yield given;
With trifluoroacetic acid In dichloromethane at 20℃; Rate constant;
With recombinant Pseudomonas nitroreducens IFO12694 γ-glutamyltranspeptidase at 30℃; for 0.0333333h; pH=10.5; aq. buffer; Enzymatic reaction;
With E. coli BL21 Star (DE3) S30 extract In aq. buffer at 37℃; for 6h; pH=7.5;
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Boc-Ala-O-N-hydroxysuccinimide
3392-05-0

Boc-Ala-O-N-hydroxysuccinimide

Boc-Ala-Glu(OBzl)-OH
17080-23-8

Boc-Ala-Glu(OBzl)-OH

Conditions
ConditionsYield
With 4-methyl-morpholine In 2,3,7,8-Tetrachloro-dibenzo[1,4]dioxine; water at 20℃; for 12 - 18h; pH=~ 9 - 9.2;100%
With potassium hydrogencarbonate In tetrahydrofuran; water at 20℃;
With 4-methyl-morpholine In 1,4-dioxane; water at 20℃; for 12h;
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

2,5-dioxopyrrolidin-1-yl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysinate
132307-50-7

2,5-dioxopyrrolidin-1-yl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysinate

Fmoc-L-Lys(Boc)-L-Glu(OBzl)-OH
1006066-87-0

Fmoc-L-Lys(Boc)-L-Glu(OBzl)-OH

Conditions
ConditionsYield
With 4-methyl-morpholine In 2,3,7,8-Tetrachloro-dibenzo[1,4]dioxine; water at 20℃; for 12 - 18h; pH=~ 9 - 9.2;100%
Boc-Leu-ONSu
3392-09-4

Boc-Leu-ONSu

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Boc-Leu-Glu(OBzl)-OH
32945-71-4

Boc-Leu-Glu(OBzl)-OH

Conditions
ConditionsYield
With 4-methyl-morpholine In 1,4-dioxane; water at 20℃; for 12h;100%
With potassium hydrogencarbonate In tetrahydrofuran; water at 20℃;
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

N-ethoxycarbonylphthalimide
22509-74-6

N-ethoxycarbonylphthalimide

(2S)-4-benzyloxicarbonyl-2-phthalimidobutanoic acid
88784-33-2

(2S)-4-benzyloxicarbonyl-2-phthalimidobutanoic acid

Conditions
ConditionsYield
With TEA In tetrahydrofuran Heating;98%
With sodium carbonate
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

benzyl-3-(3H-diazirin-3-yl)propanoate

benzyl-3-(3H-diazirin-3-yl)propanoate

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene; ammonia In methanol at 0 - 20℃; for 2h; Inert atmosphere;98%
polystyrene-NHCH2CH2N(CH2CH2NH2)2, Mn = 2180, Mw/Mn = 1.15

polystyrene-NHCH2CH2N(CH2CH2NH2)2, Mn = 2180, Mw/Mn = 1.15

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

(polystyrene)25-NHCH2CH2N(CH2CH2NH-(γ-benzyl-L-glutamate)51)2, Mn = 7460, Mw/Mn = 1.26

(polystyrene)25-NHCH2CH2N(CH2CH2NH-(γ-benzyl-L-glutamate)51)2, Mn = 7460, Mw/Mn = 1.26

Conditions
ConditionsYield
In dichloromethane at 20℃; for 24h;97%
phosgene
75-44-5

phosgene

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

5-benzyl L-glutamate N-carboxyanhydride
3190-71-4

5-benzyl L-glutamate N-carboxyanhydride

Conditions
ConditionsYield
In tetrahydrofuran; toluene at 50℃; for 1h;95.4%
In tetrahydrofuran; toluene at 50℃; for 1.16h;95.4%
In tetrahydrofuran at 50℃; for 3h; Inert atmosphere;93.5%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

5-benzyl L-glutamate N-carboxyanhydride
3190-71-4

5-benzyl L-glutamate N-carboxyanhydride

Conditions
ConditionsYield
In tetrahydrofuran at 40℃; Inert atmosphere;95.1%
at 50℃; for 12h; Inert atmosphere;94%
In ethyl acetate for 3h; Inert atmosphere; Reflux;92%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

5-benzyl L-glutamate N-carboxyanhydride
3190-71-4

5-benzyl L-glutamate N-carboxyanhydride

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; ethanol; water for 1.5h; Inert atmosphere; Reflux;95%
In tetrahydrofuran for 1.5h; Inert atmosphere; Reflux;95%
In tetrahydrofuran at 70℃; Inert atmosphere;95%
Cbz-Gly-ONSuc
2899-60-7

Cbz-Gly-ONSuc

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Z-Gly-Glu(OBzl)-OH
100736-69-4

Z-Gly-Glu(OBzl)-OH

Conditions
ConditionsYield
With calcium(II) nitrate; triethylamine In N,N-dimethyl-formamide at 20℃; for 2h; Condensation;94%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

(S)-benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate
769922-77-2

(S)-benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate

Cbz-L-Phe-L-Glu(OBn)-OH
14297-16-6

Cbz-L-Phe-L-Glu(OBn)-OH

Conditions
ConditionsYield
With triethylamine In water; acetonitrile93%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

1-O-benzyl 4-O-(2,-5-dioxopyrrolidin-1-yl) butanedioate
117679-91-1

1-O-benzyl 4-O-(2,-5-dioxopyrrolidin-1-yl) butanedioate

N-benzylsuccinyl-γ-benzyl-glutamic acid

N-benzylsuccinyl-γ-benzyl-glutamic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 18h;93%
methanol
67-56-1

methanol

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

L-glutamic acid α-methyl γ-benzyl diester hydrochloride
41089-47-8

L-glutamic acid α-methyl γ-benzyl diester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 22℃;92%
Boc-Val-ONSu
3392-12-9

Boc-Val-ONSu

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Boc-Val-Glu(OBzl)-OH

Boc-Val-Glu(OBzl)-OH

Conditions
ConditionsYield
With 4-methyl-morpholine In 1,4-dioxane; water at 20℃; for 12h;92%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

benzyl N-[(1S)-2-(1H-1,2,3-benzotriazol-1-yl)-1-methyl-2-oxoethyl]carbamate
820239-42-7

benzyl N-[(1S)-2-(1H-1,2,3-benzotriazol-1-yl)-1-methyl-2-oxoethyl]carbamate

Cbz-L-Ala-L-Glu(OBn)-OH

Cbz-L-Ala-L-Glu(OBn)-OH

Conditions
ConditionsYield
With triethylamine In water; acetonitrile91%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

C12H14ClNO3

C12H14ClNO3

Conditions
ConditionsYield
In tetrahydrofuran at 60℃; for 3h;90%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

5-benzyl L-glutamate N-carboxyanhydride
3190-71-4

5-benzyl L-glutamate N-carboxyanhydride

Conditions
ConditionsYield
With phosgene In tetrahydrofuran at 45 - 65℃; for 1.08333h;89.2%
With phosgene In tetrahydrofuran; toluene for 8h; Ambient temperature;88.3%
Multi-step reaction with 2 steps
1: aqueous KHCO3
2: PCl5
View Scheme
With bis(trichloromethyl) carbonate; α-pinene In ethyl acetate at 105℃;
With bis(trichloromethyl) carbonate
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

L-Pyroglutamic acid
98-79-3

L-Pyroglutamic acid

Conditions
ConditionsYield
With triethylamine In water; N,N-dimethyl-formamide at 40℃; for 20h;88.3%
L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

benzyl chloroformate
501-53-1

benzyl chloroformate

N-benzyloxycarbonyl-5-O-benzyl-L-glutamic acid
5680-86-4

N-benzyloxycarbonyl-5-O-benzyl-L-glutamic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate for 18h; Ambient temperature;88%
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 1h;86%
With potassium hydrogencarbonate
With potassium carbonate
With sodium hydrogencarbonate In diethyl ether
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

3-(2,5-dioxo-oxazolidin-4-yl)-propionic acid benzyl ester
5254-51-3, 3190-71-4, 10289-08-4, 13822-45-2

3-(2,5-dioxo-oxazolidin-4-yl)-propionic acid benzyl ester

Conditions
ConditionsYield
In tetrahydrofuran at 65℃; for 2h;87.6%
In tetrahydrofuran at 50℃; for 3h; Inert atmosphere;49%
In tetrahydrofuran at 45℃; for 3h;
sarcosine-N-carboxyanhydride
5840-76-6

sarcosine-N-carboxyanhydride

2,2-dimethylpropylamine
5813-64-9

2,2-dimethylpropylamine

D-glutamic acid benzyl ester-N-carboxylic anhydride

D-glutamic acid benzyl ester-N-carboxylic anhydride

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Sar125-b-p-[D-Glu(OBn)15-co-L-Glu(OBn)15]

Sar125-b-p-[D-Glu(OBn)15-co-L-Glu(OBn)15]

Conditions
ConditionsYield
Stage #1: sarcosine-N-carboxyanhydride; 2.2-dimethylpropylamine In N,N-dimethyl-formamide for 20h; Darkness;
Stage #2: D-glutamic acid benzyl ester-N-carboxylic anhydride; L-glutamic acid γ-benzyl ester In N,N-dimethyl-formamide at 25℃; for 24h;
86%
sarcosine-N-carboxyanhydride
5840-76-6

sarcosine-N-carboxyanhydride

2,2-dimethylpropylamine
5813-64-9

2,2-dimethylpropylamine

D-glutamic acid benzyl ester-N-carboxylic anhydride

D-glutamic acid benzyl ester-N-carboxylic anhydride

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Sar175-b-p-[D-Glu(OBn)25-co-L-Glu(OBn)25]

Sar175-b-p-[D-Glu(OBn)25-co-L-Glu(OBn)25]

Conditions
ConditionsYield
Stage #1: sarcosine-N-carboxyanhydride; 2.2-dimethylpropylamine In N,N-dimethyl-formamide for 20h; Darkness;
Stage #2: D-glutamic acid benzyl ester-N-carboxylic anhydride; L-glutamic acid γ-benzyl ester In N,N-dimethyl-formamide at 25℃; for 24h;
86%
sarcosine-N-carboxyanhydride
5840-76-6

sarcosine-N-carboxyanhydride

2,2-dimethylpropylamine
5813-64-9

2,2-dimethylpropylamine

D-glutamic acid benzyl ester-N-carboxylic anhydride

D-glutamic acid benzyl ester-N-carboxylic anhydride

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

Sar175-b-p-[D-Glu(OBn)25-co-L-Glu(OBn)25]

Sar175-b-p-[D-Glu(OBn)25-co-L-Glu(OBn)25]

Conditions
ConditionsYield
Stage #1: sarcosine-N-carboxyanhydride; 2.2-dimethylpropylamine In water; N,N-dimethyl-formamide; isopropyl alcohol for 20h; Darkness;
Stage #2: D-glutamic acid benzyl ester-N-carboxylic anhydride; L-glutamic acid γ-benzyl ester In N,N-dimethyl-formamide at 25℃; for 24h;
86%
phosgene
75-44-5

phosgene

L-glutamic acid γ-benzyl ester
1676-73-9

L-glutamic acid γ-benzyl ester

γ-benzyl L-glutamate N-carboxyanhydride

γ-benzyl L-glutamate N-carboxyanhydride

Conditions
ConditionsYield
In tetrahydrofuran at 45 - 48℃; for 4h;84.7%

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