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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-FLUORO-1H-BENZO[D][1,2,3]TRIAZOLE

Cas:18225-90-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1H-Benzotriazole,6-fluoro-

Cas:18225-90-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Benzotriazole, 6-fluoro-

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1H-Benzotriazole,6-fluoro-

Cas:18225-90-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-FLUORO-1H-BENZOTRIAZOLE

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

5-FLUORO-1H-BENZOTRIAZOLE

Cas:18225-90-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

18225-90-6

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-Fluoro-2H-benzotriazole cas no. 18225-90-6 98%

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 5-Fluoro-1H-benzo[d][1,2,3]triazole 5g

Cas:18225-90-6

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

5-FLUORO-1H-BENZOTRIAZOLE

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

factory?direct?sale Application:healing drugs

1H-Benzotriazole,6-fluoro-

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

5-Fluoro-1H-benzotriazoleAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Fluoro-1H-benzotriazole

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Other

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-FLUORO-1H-BENZOTRIAZOLE

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

6-Fluoro-1H-Benzotriazole

Cas:18225-90-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

5-Fluoro-1H-benzotriazole

Cas:18225-90-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

5-FLUORO-1H-BENZOTRIAZOLE

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Other

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 5-Fluoro-1H-benzotriazole, CAS:18225-90-6 with the most competitive price and the bes

5-Fluoro-1H-benzotriazole

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

1H-Benzotriazole, 6-fluoro-

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuxi Morality Chemical Co., Ltd

Do best quality products, erect the morality model Application:please email us, thanks

5-Fluoro-1H-benzotriazole

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Other

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

5-Fluoro-1H-benzotriazole

Cas:18225-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4-fluoro-1,2-phenylenediamine
367-31-7

4-fluoro-1,2-phenylenediamine

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
With tert.-butylnitrite In acetonitrile at 27 - 29℃; for 0.25h;95%
With acetic acid; sodium nitrite In water at 0 - 20℃;85%
With acetic acid; sodium nitrite In water at 20℃; Cooling with ice;85%
With acetic acid; sodium nitrite In water at 4 - 50℃;60%
1-azido-2-bromo-4-fluorobenzene
85862-81-3

1-azido-2-bromo-4-fluorobenzene

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -85 - 20℃;92%
4-fluoro-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

4-fluoro-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
With sodium azide; 18-crown-6 ether; cesium fluoride In acetonitrile at 70℃; for 12h; Inert atmosphere;50%
4-fluoro-1,2-phenylenediamine
367-31-7

4-fluoro-1,2-phenylenediamine

A

6-fluoro-1H-benzotriazole

6-fluoro-1H-benzotriazole

B

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
With acetic acid; sodium nitrite In water at 4 - 70℃; stereoselective reaction;
4-fluoroaniline
371-40-4

4-fluoroaniline

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-Bromosuccinimide / dichloromethane / 0 - 5 °C / Schlenk technique; Inert atmosphere
2.1: sulfuric acid / water / Heating
2.2: 1 h / 0 - 5 °C
2.3: 4 h / 10 - 20 °C
3.1: n-butyllithium / tetrahydrofuran; hexane / -85 - 20 °C
View Scheme
2-bromo-4-fluoroaniline
1003-98-1

2-bromo-4-fluoroaniline

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfuric acid / water / Heating
1.2: 1 h / 0 - 5 °C
1.3: 4 h / 10 - 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / -85 - 20 °C
View Scheme
Methyl phenyldiazoacetate
22979-35-7

Methyl phenyldiazoacetate

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

methyl 2-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylacetate

methyl 2-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylacetate

Conditions
ConditionsYield
With tert.-butylnitrite; p-benzoquinone In dichloromethane at 20℃; for 48h; Irradiation;86%
4-tert-Butylstyrene
1746-23-2

4-tert-Butylstyrene

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

A

2-(1-(4-tert-butylphenyl)vinyl)-5-fluoro-2H-benzo[d][1,2,3]triazole

2-(1-(4-tert-butylphenyl)vinyl)-5-fluoro-2H-benzo[d][1,2,3]triazole

B

1-(1-(4-tert-butylphenyl)vinyl)-5-fluorobenzo[d][1,2,3]triazole

1-(1-(4-tert-butylphenyl)vinyl)-5-fluorobenzo[d][1,2,3]triazole

Conditions
ConditionsYield
Stage #1: 4-tert-Butylstyrene; 5-fluoro-1H-benzo[d][1,2,3]triazole With N-iodo-succinimide In chloroform at 30℃; for 0.0833333h;
Stage #2: With potassium carbonate In methanol for 12h; Reflux; Overall yield = 80 %; regioselective reaction;
A 75%
B n/a
5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

1-(3-chloropropyl)-5-fuloro-1H-benzo[d]-[1,2,3]triazole

1-(3-chloropropyl)-5-fuloro-1H-benzo[d]-[1,2,3]triazole

Conditions
ConditionsYield
With potassium carbonate In MeCN at 20℃; for 72h;65%
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole
86386-76-7, 123632-22-4, 141113-42-0, 150024-48-9

1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

A

2-(2,4-difluorophenyl)-1-(6-fluoro-1H-benzo[d][1,2,3]-triazol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
1228885-19-5

2-(2,4-difluorophenyl)-1-(6-fluoro-1H-benzo[d][1,2,3]-triazol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

B

2-(2,4-difluorophenyl)-1-(5-fluoro-1H-benzo[d][1,2,3]-triazol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
1228885-18-4

2-(2,4-difluorophenyl)-1-(5-fluoro-1H-benzo[d][1,2,3]-triazol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40 - 80℃;A 14.9%
B 35.7%
C23H37BrO3

C23H37BrO3

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

A

C29H40FN3O3

C29H40FN3O3

B

C29H40FN3O3

C29H40FN3O3

C

C29H40FN3O3

C29H40FN3O3

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 16h; Inert atmosphere;A 33%
B 22%
C 18%
5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

5-fluoro-4,6,7-tribromo-1H-benzotriazole
1240784-77-3

5-fluoro-4,6,7-tribromo-1H-benzotriazole

Conditions
ConditionsYield
With bromine; nitric acid In water at 130℃; for 15h;22%
5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
206193-17-1

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)propanamide

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)propanamide

Conditions
ConditionsYield
Stage #1: 5-fluoro-1H-benzo[d][1,2,3]triazole With sodium hydride In tetrahydrofuran; mineral oil for 3h; Inert atmosphere; Cooling with ice;
Stage #2: (2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide In tetrahydrofuran; mineral oil at 20℃; Inert atmosphere;
12.6%
5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

3-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)-N,N,N-trimethylpropan-1-aminium iodide

3-(5-fluoro-1H-benzo[d][1,2,3]triazol-1-yl)-N,N,N-trimethylpropan-1-aminium iodide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium carbonate / MeCN / 72 h / 20 °C
2.1: potassium iodide / acetone / 2 h
2.2: 72 h / 60 °C
View Scheme
1-methylindole
603-76-9

1-methylindole

5-fluoro-1H-benzo[d][1,2,3]triazole
18225-90-6

5-fluoro-1H-benzo[d][1,2,3]triazole

A

5-fluoro-1-(3-iodo-1-methyl-1H-indol-2-yl)-1H-benzo[d][1,2,3]triazole

5-fluoro-1-(3-iodo-1-methyl-1H-indol-2-yl)-1H-benzo[d][1,2,3]triazole

B

C15H10FIN4

C15H10FIN4

C

C15H10FIN4

C15H10FIN4

Conditions
ConditionsYield
With ammonium iodide In dimethyl sulfoxide; acetonitrile at 20℃; Electrochemical reaction; Green chemistry; Overall yield = 35 percent; Overall yield = 27.3 mg;

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