Products

Refine

Country

Business Type

Certificate

Display

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 186038-82-4 with best price

Cas:186038-82-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name Diethyl 2-(1-cyano-3-methylbutyl)malonate Synonyms 2-Ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester CAS No. 186038-82-4 EINECS No.

Diethyl (1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

we are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Orga

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATECAS NO.: 186038-82-4

Cas:186038-82-4

Min.Order:1 Kilogram

FOB Price: $0.2 / 1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Diethyl(1-cyano-3-methylbutyl)malonate 186038-82-4

Cas:186038-82-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

Diethyl(1-cyano-3-methylbutyl)malonate/ LIDE PHARMA- Factory supply / Best price

Cas:186038-82-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE CAS:186038-82-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE CAS:186038-82-4

Cas:186038-82-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Diethyl(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

Diethyl 2-(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High Quality Propanedioic acid,2-(1-cyano-3-methylbutyl)-, 1,3-diethyl ester

Cas:186038-82-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Diethyl-2-(1-Cyano-3-Methylbutyl)malonate CAS No.:186038-82-4 Molecule Formula:C13H21NO4 Molecule Weight:255.31 Purity: 98.0% Package: 25kg/drum Description:White to off-white powder Manufacture Standards:Enterprise Stan

Best Quality Diethyl-2-(1-Cyano-3-Methylbutyl)malonate

Cas:186038-82-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferDIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

DIETHYL(1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE Synonyms: DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE;1-cyano-3-Methylbutyl-Propanedioic acid diethyl ester;2-Ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester;Ethyl 2-Carboxyethyl-3-Cyan

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE 186038-82-4

Cas:186038-82-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Diethyl 2-(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Diethyl(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE CAS 186038-82-4

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Propanedioic acid,2-(1-cyano-3-methylbutyl)-, 1,3-diethyl ester

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Diethyl(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Diethyl(1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE Application:186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

186038-82-4 DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

high purity Storage:normal temperature Package:DRUM Application:mainly for medical use for R&Dpurpose use only Transportation:AIR,SEA Port:BEIJING,SHANGHAI,TIANJIN,SHENZHEN

Diethyl (1-cyano-3-methylbutyl)malonate

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:White to Off-White Solid Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by Sea

DIETHYL (1-CYANO-3-METHYLBUTYL)MALONATE

Cas:186038-82-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: (R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With ethanol; sodium ethanolate at 80℃; for 20h;
Stage #2: With acetic acid In ethanol at 20℃;
100%
With sodium ethanolate In toluene
With sodium ethanolate In ethanol; toluene at 80℃;
diethyl 2-(3-methylbutylidene)malonate
51615-30-6

diethyl 2-(3-methylbutylidene)malonate

sodium cyanide
143-33-9

sodium cyanide

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 25 - 35℃; for 2 - 3h;97.97%
potassium cyanide

potassium cyanide

diethyl 2-(3-methylbutylidene)malonate
51615-30-6

diethyl 2-(3-methylbutylidene)malonate

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With acetic acid In ethanol; water at 30℃; for 0.5h;87.6%
In ethanol at 25 - 42℃; Product distribution / selectivity;
With water; N6-[[(2-Chlorophenyl)methoxy]carbonyl]-N2-[t-butyloxycarbonyl]-D-lysine In dichloromethane at 20℃; Product distribution / selectivity;
trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

diethyl 2-(3-methylbutylidene)malonate
51615-30-6

diethyl 2-(3-methylbutylidene)malonate

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In ethanol at 20℃; for 12h;
sodium cyanide
773837-37-9

sodium cyanide

diethyl 2-(3-methylbutylidene)malonate
51615-30-6

diethyl 2-(3-methylbutylidene)malonate

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With water; N-benzylcinchonidinum chloride In toluene at 20℃;
hydrogen cyanide
74-90-8

hydrogen cyanide

diethyl 2-(3-methylbutylidene)malonate
51615-30-6

diethyl 2-(3-methylbutylidene)malonate

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 20℃; for 4h; Michael Addition;
isovaleraldehyde
590-86-3

isovaleraldehyde

diethyl malonate
105-53-3

diethyl malonate

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid; di-n-propylamine / cyclohexane / 8 h / 75 °C
2: ethanol / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: tetrabutylammomium bromide; di-n-propylamine; acetic acid / hexane / 4 h / Reflux
1.2: 20 °C
2.1: acetic acid / ethanol; water / 0.5 h / 30 °C
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

(R,S)-3-cyano-5-methylhexanoic acid ethyl ester
181289-17-8

(R,S)-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With water; sodium chloride In dimethyl sulfoxide at 25 - 145℃; for 10 - 12h;94%
With sodium chloride In water; dimethyl sulfoxide at 140℃; for 9h;87.1%
With lithium chloride In water; dimethyl sulfoxide at 140℃; for 1h; Temperature;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(3S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid

(3S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid

B

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With water; Lipolase at 30℃; for 24h; pH=7.2; Potassium phosphate buffer;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With water; Pseudomonas sp. lipase at 30℃; for 24h; pH=7.2; Potassium phosphate buffer;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With water; pig liver esterase at 30℃; for 24h; pH=7.2; Potassium phosphate buffer;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(3S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid potassium salt

(3S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid potassium salt

B

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With potassium hydroxide; sodium hydroxide; water; Lipolase for 24h; pH=8.0; potassium phosphate buffer;
With potassium hydroxide; water; Lipolase for 20 - 25h; pH=7.0; calcium acetate buffer;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(S)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid sodium salt

(S)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid sodium salt

B

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
With sodium hydroxide; water; calcium acetate; Lipolase for 20 - 25h; pH=7.0;
With lipase Enzymatic reaction;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(3R)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid
1155989-27-7

(3R)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid

B

(S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid ethyl ester
1232146-79-0

(S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With water; streptomyces griseus protease at 30℃; for 24h; pH=7.2; Potassium phosphate buffer;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With water; streptomyces sp. protease at 30℃; for 24h; pH=7.2; Potassium phosphate buffer;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

(+/-)-3-cyano-5-methylhexanoic acid potassium salt

(+/-)-3-cyano-5-methylhexanoic acid potassium salt

Conditions
ConditionsYield
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With ethanol; potassium hydroxide at 75 - 80℃;
Stage #2: With water; potassium hydroxide In ethanol at 20℃; for 1h;
Stage #3: Raney nickel
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

(S)-3-cyano-5-methylhexanoic acid ethyl ester
181289-39-4

(S)-3-cyano-5-methylhexanoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester With calcium acetate hemihydrate; sodium hydroxide In water for 24h;
Stage #2: at 85℃; for 3h; Inert atmosphere;
n/a
Multi-step reaction with 3 steps
1: calcium acetate hemihydrate; sodium hydroxide / water / 24 h
2: Raney nickel water solution / water / 20 h / 2585.81 Torr
3: hydrogenchloride; acetic acid / water / 80 - 110 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide
2: Raney nickel water solution / water / 20 h / 2585.81 Torr
3: hydrogenchloride; acetic acid / water / 80 - 110 °C
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

C12H17O4(1-)*Na(1+)

C12H17O4(1-)*Na(1+)

Conditions
ConditionsYield
With sodium hydroxide
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

B

C12H17O4(1-)*Na(1+)

C12H17O4(1-)*Na(1+)

Conditions
ConditionsYield
With calcium acetate hemihydrate; sodium hydroxide In water for 24h;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

C4H11N*C12H18O4

C4H11N*C12H18O4

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: calcium acetate hemihydrate; sodium hydroxide / water / 24 h
2: isopropyl alcohol; tert-butyl methyl ether
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide
2: isopropyl alcohol; tert-butyl methyl ether
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

4-isobutyl-2-oxopyrrolidine-3-carboxylic acid

4-isobutyl-2-oxopyrrolidine-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: calcium acetate hemihydrate; sodium hydroxide / water / 24 h
2: Raney nickel water solution / water / 20 h / 2585.81 Torr
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide
2: Raney nickel water solution / water / 20 h / 2585.81 Torr
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

pregabilin
148553-50-8

pregabilin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: calcium acetate hemihydrate; sodium hydroxide / water / 24 h
1.2: 3 h / 85 °C / Inert atmosphere
2.1: potassium hydroxide / water; Isopropyl acetate / 1 h / 20 °C
2.2: 5 h
View Scheme
Multi-step reaction with 4 steps
1.1: calcium acetate hemihydrate; sodium hydroxide / water / 24 h
2.1: Raney nickel water solution / water / 20 h / 2585.81 Torr
3.1: hydrogenchloride; acetic acid / water / 80 - 110 °C
4.1: potassium hydroxide / water; Isopropyl acetate / 1 h / 20 °C
4.2: 5 h
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide
2.1: Raney nickel water solution / water / 20 h / 2585.81 Torr
3.1: hydrogenchloride; acetic acid / water / 80 - 110 °C
4.1: potassium hydroxide / water; Isopropyl acetate / 1 h / 20 °C
4.2: 5 h
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
871577-68-3

(R)-2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

B

(S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid ethyl ester
1232146-79-0

(S)-3-cyano-2-ethoxycarbonyl-5-methyl-hexanoic acid ethyl ester

Conditions
ConditionsYield
In aq. phosphate buffer pH=7.2; Resolution of racemate;
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

racemic 3-cyano-5-methylhexanoic acid
181289-16-7

racemic 3-cyano-5-methylhexanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium chloride / dimethyl sulfoxide; water / 1 h / 140 °C
2: sodium hydroxide; water / 0.5 h / 20 °C / pH 8
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

(R,S)-3-iso-butyl-4-aminobutyric acid
128013-69-4, 130912-52-6, 148553-50-8, 148553-51-9

(R,S)-3-iso-butyl-4-aminobutyric acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: lithium chloride / dimethyl sulfoxide; water / 1 h / 140 °C
2: sodium hydroxide; water / 0.5 h / 20 °C / pH 8
3: hydrogen / 18 h / 80 °C / 6750.68 Torr
View Scheme
Multi-step reaction with 3 steps
1: sodium chloride / water; dimethyl sulfoxide / 9 h / 140 °C
2: potassium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2 h / 20 °C / Cooling with ice
3: sodium hydroxide / water / 0 - 10 °C
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

A

pregabilin
148553-50-8

pregabilin

B

(R)-pregabalin

(R)-pregabalin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: lithium chloride / dimethyl sulfoxide; water / 1 h / 140 °C
2: sodium hydroxide; water / 0.5 h / 20 °C / pH 8
3: hydrogen / 18 h / 80 °C / 6750.68 Torr
4: lipase Lipolase 100T / aq. phosphate buffer / 24 h / 30 °C / pH 7.5
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

(R)-pregabalin

(R)-pregabalin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium chloride / water; dimethyl sulfoxide / 9 h / 140 °C
2: potassium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2 h / 20 °C / Cooling with ice
3: sodium hydroxide / water / 0 - 10 °C
4: (S)-Mandelic acid / isopropyl alcohol / 0.5 h / 60 °C
View Scheme
2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester
186038-82-4

2-ethoxycarbonyl-3-cyano-5-methylhexanoic acid ethyl ester

3-carbamoyl-5-methylhexanoic acid

3-carbamoyl-5-methylhexanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium chloride / water; dimethyl sulfoxide / 9 h / 140 °C
2: potassium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2 h / 20 °C / Cooling with ice
View Scheme

Downstream Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View