Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:2140-76-3
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inquiryItem Quality Standard Test Result Appearance colorless clear liquid colorless clear liquid Assay %
Cas:2140-76-3
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryUnique advantages of 2'-O-Methyluridine Cas 2140-76-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder Storage:Cool dry place Pa
Cas:2140-76-3
Min.Order:100 Gram
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:2140-76-3
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inquiry2'-O-Methyluridine Basic information Product Name: 2'-O-Methyluridine Synonyms: 2'-O-METHYLURIDINE (CHIRAL);2''-O-METHYLURIDINE CRYSTALLINE;1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidine-2,4-
With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:2140-76-3
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:2140-76-3
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:2140-76-3
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiryPRODUCT DETAILS
Cas:2140-76-3
Min.Order:500 Kilogram
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Type:Lab/Research institutions
inquiryAppearance:White to off-white powder Storage:Store at 0°C Package:As customer request Application:Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replica
Cas:2140-76-3
Min.Order:100 Gram
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Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:2140-76-3
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inquiryNewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
Cas:2140-76-3
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:2140-76-3
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
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Type:Lab/Research institutions
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:2140-76-3
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inquiryProduct name: 2'-Methyoxy Uridine CAS No.: 2140-76-3 Molecule Formula:C10H14N2O6 Molecule Weight:258.23 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard
Cas:2140-76-3
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryHigh quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle
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inquiry2'-O-Methyluridine Basic information Product Name: 2'-O-Methyluridine Synonyms: 2'-O-METHYLURIDINE (CHIRAL);2''-O-METHYLURIDINE CRYSTALLINE;1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidine-2,4-
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:2140-76-3
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inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:2140-76-3
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Type:Trading Company
inquiry1'-(3',5'-O-benzyl-2'-O-methyl-β-D-ribofuranosyl)uracil
2'-O-methyluridine
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethyl acetate at 25℃; under 760 Torr; for 0.5h; | 99% |
3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disilyl)-2'-O-methyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h; | 95% |
With potassium fluoride; tetraethylammonium bromide In methanol; water | 78% |
With potassium fluoride; tetraethylammonium chloride In water; acetonitrile at 53℃; for 0.5h; | 69 % Spectr. |
With tetrabutyl ammonium fluoride In tetrahydrofuran |
C25H28N2O7
2'-O-methyluridine
Conditions | Yield |
---|---|
With formic acid; palladium on activated charcoal; hydrogen In water; isopropyl alcohol under 760.051 Torr; for 12h; | 95% |
3',5'-O-1,1,3,3-tetraisopropyldisiloxyl-2'-O-methyl-3-N-(2,4-dinitrobenzene)sulfenyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.0333333h; | 92% |
Conditions | Yield |
---|---|
With Trimethyl borate; sodium carbonate In methanol at 140 - 150℃; Ring cleavage; | 92% |
magnesium ethylate
O2,2'-anhydro-1-(β-D-arabinofuranosyl)uracil
2'-O-methyluridine
Conditions | Yield |
---|---|
In methanol for 5h; Reflux; Large scale; | 92% |
2,2'-Anhydrouridine
magnesium methanolate
2'-O-methyluridine
Conditions | Yield |
---|---|
In methanol for 5h; Heating; | 88% |
3',5'-di-O-benzoyl-2'-O-methyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol Ambient temperature; | 86% |
Trimethyl borate
1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one
2'-O-methyluridine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; trimethyl orthoformate In methanol at 150℃; under 10343 Torr; for 42h; | 86% |
2'-O-methyl-5'-O-(monomethoxytrityl)uridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With acetic acid Ambient temperature; | 85% |
3-(4-methoxyphenylmethyl)-2'-O-methyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With aluminium trichloride; methoxybenzene at 65℃; for 2h; | 81% |
2'-O-methyl-3-N-(2-nitrobenzene)sulfenyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With triethylammonium thiocresolate In pyridine; acetonitrile for 0.166667h; | 81% |
3',5'-O-1,1,3,3-tetraisopropyldisiloxyl-2'-O-methyl-3-N-(2-nitrobenzene)sulfenyluridine
A
2'-O-methyl-3-N-(2-nitrobenzene)sulfenyluridine
B
2'-O-methyluridine
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.0333333h; | A 81% B 10% |
2'-O-methyluridine
Conditions | Yield |
---|---|
Stage #1: 1-((2R,3R,3aR,9aR)-3-Chloromethoxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1H-pyrimidine-2,4-dione With sodium tetrahydroborate In N,N-dimethyl-formamide Stage #2: With potassium fluoride In tetrahydrofuran | 18% |
1-methyl-1-nitrosourea
uridine
A
3-methyluridine
B
2'-O-methyluridine
Conditions | Yield |
---|---|
With borax In water; formamide at 50℃; for 18h; | A 11% B n/a |
diazomethane
uridine
A
3'-O-methyluridine
B
2'-O-methyluridine
Conditions | Yield |
---|---|
With tin(ll) chloride In N,N-dimethyl-formamide at 50℃; Title compound not separated from byproducts; | |
With tin(ll) chloride In N,N-dimethyl-formamide at 0℃; Title compound not separated from byproducts; |
1-[6-methoxy-2,2-dimethyl-(3aR,5R,6R,6aR)-perhydrofuro-[2,3-d][1,3]dioxol-5-yl]-(1R)-ethane-1,2-diol
1,3-bis(trimethylsilyl)uracil
2'-O-methyluridine
Conditions | Yield |
---|---|
Multistep reaction; |
3-N-(trimethylsilyl)ethoxymethyl-2'-O-methyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran Heating; |
3-N-(trimethylsilyl)ethoxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Af2O / 7 h / Heating 2: TBAF / tetrahydrofuran / 0.25 h / 0 °C 3: TBAF / tetrahydrofuran / Heating View Scheme |
3-N-(trimethylsilyl)ethoxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-O-methyluridine
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: TBAF / tetrahydrofuran / 0.25 h / 0 °C 2: TBAF / tetrahydrofuran / Heating View Scheme |
3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 75 percent / i-Pr2NEt / CH2Cl2 / Ambient temperature 2: Af2O / 7 h / Heating 3: TBAF / tetrahydrofuran / 0.25 h / 0 °C 4: TBAF / tetrahydrofuran / Heating View Scheme | |
Multi-step reaction with 6 steps 1: triethylamine / CH2Cl2 / 0.25 h / 20 °C 2: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 3: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 4: 81 percent / silver oxide / acetone / 72 h / 20 °C 5: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 6: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme | |
Multi-step reaction with 6 steps 1: 87 percent / pyridine / 0 °C 2: 83 percent / pyridine / Ambient temperature 3: 77 percent / t-butylamine / methanol / 0.33 h / Ambient temperature 4: 93 percent / Ag2O / 7 h / Ambient temperature 5: 86 percent / zinc powder, acetylacetone / pyridine / 0.25 h / Ambient temperature 6: 69 percent Spectr. / potassium fluoride, tetraethylammonium chloride / acetonitrile; H2O / 0.5 h / 53 °C View Scheme |
1,3,5-tri-O-benzoyl-2-O-methyl-α-D-ribofuranose
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 75 percent / trimethylsilyl trifluoromethanesulfonate / acetonitrile / 0.5 h / Ambient temperature 2: 86 percent / conc. aq. NH4OH / methanol / Ambient temperature View Scheme |
1,3,5-tri-O-benzoyl-α-D-ribofuranoside
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 71 percent / CH2N2, BF3*OEt2 / CH2Cl2 / 0.5 h / 4 °C 2: 75 percent / trimethylsilyl trifluoromethanesulfonate / acetonitrile / 0.5 h / Ambient temperature 3: 86 percent / conc. aq. NH4OH / methanol / Ambient temperature View Scheme |
1-(3',5'-O-1,1,3,3-tetraisopropyl-1,3-disilyl)-β-D-ribofuranosyl-4-(2-nitrophenyl)-2-pyrimidinone
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 81 percent / silver oxide / acetone / 72 h / 20 °C 2: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 3: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme |
1-(3',5'-O-1,1,3,3-tetraisopropyl-1,3-disilyl)-β-D-ribofuranosyl-2'-O-methyl-4-(2-nitrophenyl)-2-pyrimidinone
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 2: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme |
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 2: 81 percent / silver oxide / acetone / 72 h / 20 °C 3: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 4: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme |
3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-O-(trimethylsilyl)uridine
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 2: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 3: 81 percent / silver oxide / acetone / 72 h / 20 °C 4: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 5: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: pyridine / 20 °C 2: triethylamine / CH2Cl2 / 0.25 h / 20 °C 3: 1.) triethylamine, 2-mesitylenesulfonyl chloride, N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane / 1.) dichloromethane, 30 min, 2.) dichloromethane, 60 min 4: 1.12 g / p-toluenesulfonic acid / CH2Cl2 / 0.03 h / 20 °C 5: 81 percent / silver oxide / acetone / 72 h / 20 °C 6: 70 percent / syn-4-nitrobenxaldoxime, N1,N1,N3,N3-tetramethylguanidine / dioxane; H2O / 16 h / 20 °C 7: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 2: Ag2O / acetone / 16 h / 20 °C 3: 92 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.03 h / 20 °C View Scheme | |
Multi-step reaction with 4 steps 2: 94 percent / Ag2O / acetone / 16 h / 20 °C 3: 81 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.03 h / 20 °C 4: 81 percent / triethylammonium thiocresolate / pyridine; acetonitrile / 0.17 h View Scheme | |
Multi-step reaction with 3 steps 2: 94 percent / Ag2O / acetone / 16 h / 20 °C 3: 10 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.03 h / 20 °C View Scheme |
N3-<(2-nitrophenyl)sulfenyl>-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine
2'-O-methyluridine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 94 percent / Ag2O / acetone / 16 h / 20 °C 2: 81 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.03 h / 20 °C 3: 81 percent / triethylammonium thiocresolate / pyridine; acetonitrile / 0.17 h View Scheme | |
Multi-step reaction with 2 steps 1: 94 percent / Ag2O / acetone / 16 h / 20 °C 2: 10 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.03 h / 20 °C View Scheme |
acetic anhydride
2'-O-methyluridine
3',5'-di-O-acetyl-2'-O-methyluridine
Conditions | Yield |
---|---|
With pyridine Acetylation; | 100% |
With pyridine; dmap at 20℃; | 95% |
With pyridine at 20℃; for 6h; Acetylation; | 93% |
With pyridine at 20℃; for 18h; | |
In pyridine at 20℃; for 18h; |
tert-butylchlorodiphenylsilane
2'-O-methyluridine
Conditions | Yield |
---|---|
Stage #1: 2'-O-methyluridine With pyridine; tert-butyldimethylsilyl chloride at 20℃; for 12h; Stage #2: tert-butylchlorodiphenylsilane With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 12h; Stage #3: With toluene-4-sulfonic acid In methanol at 20℃; for 3h; | 93% |
2'-O-methyluridine
5-bromo-2'-O-methyluridine
Conditions | Yield |
---|---|
With sodium azide; bromoisocyanuric acid monosodium salt In water; acetonitrile at 20℃; for 1.5h; | 93% |
Stage #1: 2'-O-methyluridine With sodium azide In 1,2-dimethoxyethane; water at 22℃; for 0.25h; Inert atmosphere; Stage #2: With N-Bromosuccinimide In 1,2-dimethoxyethane; water at 22℃; for 24h; Inert atmosphere; | 88% |
2'-O-methyluridine
O-levulinyl acetonoxime
5’-O-levulinoyl-2’-O-methyluridine
Conditions | Yield |
---|---|
With Candida antarctica lipase B In tetrahydrofuran at 30℃; for 1h; Inert atmosphere; Enzymatic reaction; regioselective reaction; | 92% |
2'-O-methyluridine
Conditions | Yield |
---|---|
With iodine; triphenylphosphine In pyridine; acetonitrile at 20℃; for 48h; Inert atmosphere; | 91% |
With 1H-imidazole; iodine; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 3h; | 86% |
With 1H-imidazole; iodine; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 3h; | 86% |
4,4'-dimethoxytrityl chloride
2'-O-methyluridine
5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine
Conditions | Yield |
---|---|
With pyridine for 0.75h; Inert atmosphere; | 90% |
With pyridine at 0 - 20℃; |
2'-O-methyluridine
1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With ammonium cerium (IV) nitrate; iodine In acetonitrile at 80℃; for 1h; | 86% |
With ammonium cerium(IV) nitrate; iodine; acetic acid at 80℃; | 74% |
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 24h; | 85% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 24h; | 85% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 24h; | 85% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 24h; | 85% |
With 1H-imidazole In N,N-dimethyl-formamide |
succinic acid anhydride
4,4'-dimethoxytrityl chloride
triethylamine
2'-O-methyluridine
Conditions | Yield |
---|---|
Stage #1: 4,4'-dimethoxytrityl chloride; triethylamine; 2'-O-methyluridine In N,N-dimethyl-formamide for 2h; Stage #2: succinic acid anhydride With 1-methyl-1H-imidazole In N,N-dimethyl-formamide | 83.9% |
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide for 3h; Heating; | 75% |
2'-O-methyluridine
Conditions | Yield |
---|---|
With carbon tetrabromide; triphenylphosphine In N,N-dimethyl-formamide at 20℃; for 4h; | 71% |
p-toluenesulfonyl chloride
2'-O-methyluridine
2'-O-methyl-5'-O-p-tolylsulfonyluridine
Conditions | Yield |
---|---|
In pyridine Ambient temperature; overnight; | 60% |
2,7-dimethyl-9-(4-nitrophenyl)-xanthen-9-ol
2'-O-methyluridine
5'-O-DMPx-2-O-Me-uridine
Conditions | Yield |
---|---|
Stage #1: 2'-O-methyluridine With tris(pentafluorophenyl)borate In dichloromethane at 20℃; for 0.5h; Stage #2: 2,7-dimethyl-9-(4-nitrophenyl)-xanthen-9-ol In dichloromethane at 20℃; for 3h; Inert atmosphere; regioselective reaction; | 60% |
Conditions | Yield |
---|---|
With pyridine at -78 - 20℃; for 1h; | 50% |
With pyridine at -78 - 20℃; for 1h; | 50% |
With pyridine at -78 - 20℃; for 1h; | 50% |
With pyridine at -78 - 20℃; for 1h; | 50% |
2'-O-methyluridine
C10H12N2O7
Conditions | Yield |
---|---|
With dipotassium peroxodisulfate; ruthenium(III) chloride trihydrate; potassium hydroxide In water at 25℃; | 41% |
Conditions | Yield |
---|---|
In water at 105℃; for 48h; | 32% |
In water at 105℃; for 48h; | 32% |
In water at 105℃; for 48h; | 32% |
In water at 105℃; for 48h; | 32% |
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