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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Tengzhou Runlong Fragrance Co., Ltd.

1、Our factory passed ISO 9001, ISO 14001, ISO 22000 system certification; HALAL 、KOSHER、FCC AND FDA certificate are available. We can provide customers with better prices, and the supply is stable. 2、We founded in 2004,10% of the staff have more tha

FEMA 3126 Food flavor Acetylpyrazine CAS NO 22047-25-2

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Shandong Promise New Material Co., ltd.

We have the best quality of China,our product exports to all over the world. It is widely used in many different kinds of flavors and fragrances area.We our quality means the best in China,even all over the world.We can export according to customers

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $100.0

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 22047-25-2 Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Acetylpyrazine ? supplier in China

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience 2. Free samples will be provided,ensure specifications and quality are right for customer 3. Customers will receive the most professional techn

Large Stock 99.0% Acetylpyrazine 22047-25-2 Producer

Cas:22047-25-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

High Quality 2-Acetylpyrazine

Cas:22047-25-2

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Acetyl pyrazine

Cas:22047-25-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

top quality 22047-25-2 99%min White powder/large production of Product Name: Acetylpyrazine Synonyms: 1-pyrazinylethanone;1-pyrazinyl-Ethanone;Ethanone, 1-pyrazinyl-;Ethanone,1-pyrazinyl-;K

top quality 22047-25-2 99%min White powder/large production of

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Acetylpyrazine

Cas:22047-25-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--22047-25-2--Acetylpyrazine in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relationshi

TIANFUCHEM--22047-25-2--Acetylpyrazine in stock

Cas:22047-25-2

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name Acetylpyrazine CAS No. 22047-25-2 Appearance light yellow crystalline

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 22047-25-2 with best quality

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material Flavor Enhancer 22047-25-2 Acetylpyrazine

Cas:22047-25-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2-Acetylpyrazine/ LIDE PHARMA- Factory supply / Best price

Cas:22047-25-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $102.0 / 115.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name 2-Acetyl Pyrazine CAS 22047-25-2 EINECS 244-753-5 FEMA 3126 Appearance White to pale yellow crystall

2-Acetyl Pyrazine CAS:22047-25-2

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED intermediat

2-Acetyl PyrazineCAS NO.: 22047-25-2

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Acetylpyrazine 99%/2-Acetylpyrazine CAS 22047-25-2

Cas:22047-25-2

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Ethanone,1-(2-pyrazinyl)- 22047-25-2

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $72.0 / 84.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Acetylpyrazine CAS: 22047-25-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

Acetylpyrazine CAS: 22047-25-2

Cas:22047-25-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Ethanone,1-(2-pyrazinyl)-

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

Acetylpyrazine CAS NO.22047-25-2

Cas:22047-25-2

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

2-acetylpyrazine

Cas:22047-25-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

2-Acetyl Pyrazine Acetylpyrazine Acetyl Pyrazine cas 22047-25-2

Cas:22047-25-2

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

2-Acetylpyrazine CAS: 22047-25-2 Specification Item Standard Test Results Identification A.H-NMR:Comply with the structure Complies B.LC-MS:Comply with the

Factory supply 2-Acetylpyrazine

Cas:22047-25-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory sales Acetylpyrazine/2-acetyl pyrazine CAS 22047-25-2

Cas:22047-25-2

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Synthetic route

1,4-pyrazine
290-37-9

1,4-pyrazine

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With NH4S2O8; silver nitrate; trifluoroacetic acid In dichloromethane; water at 40℃; for 2.5h;100%
With ferrous(II) sulfate heptahydrate; ammonium peroxydisulfate; sulfuric acid In dichloromethane; water at 40℃; Reagent/catalyst; Solvent; Minisci Aromatic Substitution;26%
1-(pyrazin-2-yl)butan-1-one
61892-81-7

1-(pyrazin-2-yl)butan-1-one

A

acetylpyrazine
22047-25-2

acetylpyrazine

B

2-Methyl-1-pyrazin-2-yl-cyclopropanol
138836-01-8, 138836-02-9

2-Methyl-1-pyrazin-2-yl-cyclopropanol

Conditions
ConditionsYield
In tert-butyl alcohol; benzene for 4h; Irradiation;A 1%
B 95%
3-acetylpyrazine N-oxide
120992-58-7

3-acetylpyrazine N-oxide

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With Eosin Y; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate In acetonitrile at 20℃; for 3h; Inert atmosphere; Irradiation; chemoselective reaction;90%
3-methyl-1-(pyrazin-2-yl)butan-1-one
86461-64-5

3-methyl-1-(pyrazin-2-yl)butan-1-one

A

acetylpyrazine
22047-25-2

acetylpyrazine

B

2,2-dimethyl-1-(pyrazin-2-yl)cyclopropanol
138836-03-0

2,2-dimethyl-1-(pyrazin-2-yl)cyclopropanol

Conditions
ConditionsYield
In tert-butyl alcohol; benzene for 4h; Irradiation;A 2%
B 86%
2-pyrazine carbonitrile
19847-12-2

2-pyrazine carbonitrile

methylene chloride
74-87-3

methylene chloride

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
Stage #1: methylene chloride With iodine; magnesium In tetrahydrofuran at 60℃; for 2h; Inert atmosphere;
Stage #2: 2-pyrazine carbonitrile With copper(l) chloride In tetrahydrofuran at 50℃; for 14h; Inert atmosphere;
Stage #3: With water In tetrahydrofuran Temperature; Reagent/catalyst; Solvent; Inert atmosphere;
69%
C6H6Cl2N2

C6H6Cl2N2

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With sodium hydrogencarbonate; dimethyl sulfoxide at 80℃; for 6h;60%
1,4-pyrazine
290-37-9

1,4-pyrazine

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

A

acetylpyrazine
22047-25-2

acetylpyrazine

B

1,1′-(pyrazine-2,5-diyl)diethanone
39248-49-2

1,1′-(pyrazine-2,5-diyl)diethanone

Conditions
ConditionsYield
With ferrous(II) sulfate heptahydrate; ammonium peroxydisulfate; formic acid; dimethyl sulfoxide In dichloromethane; water at 40℃; Catalytic behavior; Reagent/catalyst; Solvent; Minisci Aromatic Substitution;A 58%
B 10%
With ferrous(II) sulfate heptahydrate; ammonium peroxydisulfate; sulfuric acid In water at 50℃; Minisci Aromatic Substitution;A 26%
B 33%
1,4-pyrazine
290-37-9

1,4-pyrazine

acetaldehyde
75-07-0

acetaldehyde

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With tert.-butylhydroperoxide; di-tert-butyl peroxide; iron(II) sulfate In dichloromethane; sulfuric acid at 5℃; for 1h;50%
2-pyrazine carbonitrile
19847-12-2

2-pyrazine carbonitrile

methyl magnesium iodide
917-64-6

methyl magnesium iodide

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
In diethyl ether at 20℃; for 1h; Addition;42%
In diethyl ether at -10 - 10℃; for 1h;40%
Stage #1: 2-pyrazine carbonitrile; methyl magnesium iodide In diethyl ether
Stage #2: With water
2-(3,3-dimethylbutyryl)pyrazine
138835-87-7

2-(3,3-dimethylbutyryl)pyrazine

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
In hexane for 20h; Irradiation;15%
In tert-butyl alcohol; benzene for 5h; Quantum yield; Irradiation;
2-pyrazine carbonitrile
19847-12-2

2-pyrazine carbonitrile

methylmagnesium bromide
75-16-1

methylmagnesium bromide

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With diethyl ether
1,4-pyrazine
290-37-9

1,4-pyrazine

acetaldehyde
75-07-0

acetaldehyde

A

acetylpyrazine
22047-25-2

acetylpyrazine

B

1,1′-(pyrazine-2,5-diyl)diethanone
39248-49-2

1,1′-(pyrazine-2,5-diyl)diethanone

Conditions
ConditionsYield
With tert.-butylhydroperoxide; sulfuric acid; iron(II) sulfate In water; benzene Yields of byproduct given;A 28 % Chromat.
B n/a
1H-imidazole
288-32-4

1H-imidazole

C6H5N2O(1-)*K(1+)

C6H5N2O(1-)*K(1+)

A

acetylpyrazine
22047-25-2

acetylpyrazine

B

imidazole potassium salt
20671-53-8

imidazole potassium salt

Conditions
ConditionsYield
In dimethyl sulfoxide at 24.9℃; Equilibrium constant;
pyrazinamide
98-96-4

pyrazinamide

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / POCl3 / 1.5 h / 100 °C
2: 40 percent / diethyl ether / 1 h / -10 - 10 °C
View Scheme
2-pyrazine carbonitrile
19847-12-2

2-pyrazine carbonitrile

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.) H+, H2O
2: 2-methyl-propan-2-ol; benzene / 5 h / Irradiation
View Scheme
L-serin
56-45-1

L-serin

L-lysine
56-87-1

L-lysine

D-glucose
50-99-7

D-glucose

A

1,4-pyrazine
290-37-9

1,4-pyrazine

B

2-Methylpyrazine
109-08-0

2-Methylpyrazine

C

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

D

2,3-dimethylpyrazine
5910-89-4

2,3-dimethylpyrazine

E

acetylpyrazine
22047-25-2

acetylpyrazine

F

2-ethyl-3,6-dimethylpyrazine
13360-65-1

2-ethyl-3,6-dimethylpyrazine

G

2,6-dimethylpyrazine
108-50-9

2,6-dimethylpyrazine

H

2,3,5-trimethylpyrazine
14667-55-1

2,3,5-trimethylpyrazine

I

2-ethyl-6-methylpyrazine
13925-03-6

2-ethyl-6-methylpyrazine

J

2-ethyl-5-methypyrazine
13360-64-0

2-ethyl-5-methypyrazine

Conditions
ConditionsYield
In water at 130℃; for 2h; pH=8; Maillard reaction;
L-lysine
56-87-1

L-lysine

D-glucose
50-99-7

D-glucose

A

1,4-pyrazine
290-37-9

1,4-pyrazine

B

2-Methylpyrazine
109-08-0

2-Methylpyrazine

C

2,5-dimethyl-pyrazine
123-32-0

2,5-dimethyl-pyrazine

D

2,3-dimethylpyrazine
5910-89-4

2,3-dimethylpyrazine

E

acetylpyrazine
22047-25-2

acetylpyrazine

F

2-ethyl-3,6-dimethylpyrazine
13360-65-1

2-ethyl-3,6-dimethylpyrazine

G

2,6-dimethylpyrazine
108-50-9

2,6-dimethylpyrazine

H

2,3,5-trimethylpyrazine
14667-55-1

2,3,5-trimethylpyrazine

I

2-ethyl-3,5-dimethylpyrazine
13925-07-0

2-ethyl-3,5-dimethylpyrazine

J

2-ethyl-5-methypyrazine
13360-64-0

2-ethyl-5-methypyrazine

Conditions
ConditionsYield
In water at 130℃; for 2h; pH=8; Maillard reaction;
2-ethylpyrazine
13925-00-3

2-ethylpyrazine

acetylpyrazine
22047-25-2

acetylpyrazine

Conditions
ConditionsYield
With tert.-butylhydroperoxide In water at 60℃; for 12h;66 %Spectr.
acetylpyrazine
22047-25-2

acetylpyrazine

2-bromo-1-pyrazin-2-yl-ethan-1-one hydrobromide
126353-32-0

2-bromo-1-pyrazin-2-yl-ethan-1-one hydrobromide

Conditions
ConditionsYield
With pyridinium hydrobromide perbromide; hydrogen bromide In water; acetic acid at 20℃; for 0.1h;100%
With hydrogen bromide; bromine In water at 80 - 90℃; for 1h;82%
With pyridinium hydrobromide perbromide; hydrogen bromide; acetic acid at 20℃; for 1h;
With hydrogen bromide; bromine; acetic acid at 23℃; for 4h; Inert atmosphere;
acetylpyrazine
22047-25-2

acetylpyrazine

5-amino isophthaloyl hydrazide

5-amino isophthaloyl hydrazide

C20H19N9O2

C20H19N9O2

Conditions
ConditionsYield
With acetic acid In ethanol Reflux;100%
acetylpyrazine
22047-25-2

acetylpyrazine

1-(1-phenylethyl)-2-methyleneaziridine

1-(1-phenylethyl)-2-methyleneaziridine

2-pyrazin-2-yl-4-methyl-1-(1-phenylethyl)pyrrole

2-pyrazin-2-yl-4-methyl-1-(1-phenylethyl)pyrrole

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) at 120℃; for 72h;96%
Dimethyl oxalate
553-90-2

Dimethyl oxalate

acetylpyrazine
22047-25-2

acetylpyrazine

4-(2-pyrazinyl)-2,4-dioxobutanoic acid methyl ester
858599-85-6

4-(2-pyrazinyl)-2,4-dioxobutanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: acetylpyrazine With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.75h;
Stage #2: Dimethyl oxalate In tetrahydrofuran for 0.166667h;
96%
acetylpyrazine
22047-25-2

acetylpyrazine

thieno[2,3-d]pyrimidin-4-ylhydrazine
14080-58-1

thieno[2,3-d]pyrimidin-4-ylhydrazine

4-(2-(1-(pyrazin-2-yl)ethylidene)hydrazinyl)thieno[2,3-d]pyrimidine

4-(2-(1-(pyrazin-2-yl)ethylidene)hydrazinyl)thieno[2,3-d]pyrimidine

Conditions
ConditionsYield
In ethanol for 24h; Reflux;96%
acetylpyrazine
22047-25-2

acetylpyrazine

2-(1-hydroxyethyl)pyrazine
94777-52-3

2-(1-hydroxyethyl)pyrazine

Conditions
ConditionsYield
Stage #1: acetylpyrazine With C27H43AlClN3Si3; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In neat (no solvent) at 20℃; for 16h;
Stage #2: With silica gel at 20℃; Catalytic behavior;
95%
With sodium tetrahydroborate In methanol Ambient temperature;
With lithium aluminium tetrahydride In diethyl ether at -78℃; for 1h;
acetylpyrazine
22047-25-2

acetylpyrazine

isoniazid
54-85-3

isoniazid

N’-(1-(pyrazin-2-yl)ethylidene)isonicotinohydrazide

N’-(1-(pyrazin-2-yl)ethylidene)isonicotinohydrazide

Conditions
ConditionsYield
With formic acid In ethanol for 4h; Reflux;95%
With formic acid In ethanol for 5h; Reflux;90%
In methanol for 4h; Reflux;64%
acetylpyrazine
22047-25-2

acetylpyrazine

ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

dihydro-5-methyl-5-(2-pyradinyl)-2(3H)-furanone

dihydro-5-methyl-5-(2-pyradinyl)-2(3H)-furanone

Conditions
ConditionsYield
dodecacarbonyl-triangulo-triruthenium In toluene at 140℃; for 20h;94%
acetylpyrazine
22047-25-2

acetylpyrazine

2-benzyl-3-hydroxy-2,3-dihydro-isoindol-1-one
17448-14-5

2-benzyl-3-hydroxy-2,3-dihydro-isoindol-1-one

2-benzyl-3-(2-oxo-2-(pyrazin-2-yl)ethyl)isoindolin-1-one

2-benzyl-3-(2-oxo-2-(pyrazin-2-yl)ethyl)isoindolin-1-one

Conditions
ConditionsYield
With Sn(4+)*4C2F6NO4S2(1-)*8C2H6OS In toluene at 110℃; for 24h; Inert atmosphere; Sealed tube;94%
acetylpyrazine
22047-25-2

acetylpyrazine

4-bromophenylhydrazine hydrochloride
622-88-8

4-bromophenylhydrazine hydrochloride

2-acetylpyrazine 4-bromophenylhydrazone

2-acetylpyrazine 4-bromophenylhydrazone

Conditions
ConditionsYield
With sodium acetate In ethanol; chloroform for 12h; Ambient temperature;93.5%
acetylpyrazine
22047-25-2

acetylpyrazine

1,3-benzothiazol-2-ylhydrazine
615-21-4

1,3-benzothiazol-2-ylhydrazine

N-Benzothiazol-2-yl-N'-[1-pyrazin-2-yl-eth-(E)-ylidene]-hydrazine

N-Benzothiazol-2-yl-N'-[1-pyrazin-2-yl-eth-(E)-ylidene]-hydrazine

Conditions
ConditionsYield
With acetic acid In methanol at 80℃;93%
acetylpyrazine
22047-25-2

acetylpyrazine

picolinic acid hydrazide
1452-63-7

picolinic acid hydrazide

N′-(1-(pyrazin-2-yl)ethylidene)picolinohydrazide

N′-(1-(pyrazin-2-yl)ethylidene)picolinohydrazide

Conditions
ConditionsYield
With formic acid In ethanol for 5h; Reflux;93%
In ethanol
acetylpyrazine
22047-25-2

acetylpyrazine

C6H8N2O

C6H8N2O

Conditions
ConditionsYield
Stage #1: acetylpyrazine With trimethylaluminum; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; 3,3'-bis-(3,5-bis-trifluoromethyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol In toluene at 20℃; for 2h; Glovebox; Inert atmosphere;
Stage #2: With methanol for 0.5h; enantioselective reaction;
93%
pent-4-en-2-ynyl-carbamic acid tert-butyl ester

pent-4-en-2-ynyl-carbamic acid tert-butyl ester

acetylpyrazine
22047-25-2

acetylpyrazine

[2-(1-hydroxy-1-pyrazin-2-yl-ethyl)-penta-2,4-dienyl]-carbamic acid tert-butyl ester

[2-(1-hydroxy-1-pyrazin-2-yl-ethyl)-penta-2,4-dienyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With (R)-xylyl-WALPHOS; triphenylacetic acid; hydrogen; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate In 1,2-dichloro-ethane at 40℃; under 760 Torr;92%
acetylpyrazine
22047-25-2

acetylpyrazine

C9H6F3NO2

C9H6F3NO2

(S)-4,4,4-trifluoro-3-(nitromethyl)-3-phenyl-1-(pyrazin-2-yl)butan-1-one

(S)-4,4,4-trifluoro-3-(nitromethyl)-3-phenyl-1-(pyrazin-2-yl)butan-1-one

Conditions
ConditionsYield
Stage #1: acetylpyrazine With bis(acetylacetonate)nickel(II); (S,S)-2,2'-isopropylidenebis(4-phenyl-2-oxazoline) In isopropyl alcohol at 0℃; for 0.5h; Michael Addition; Schlenk technique; Inert atmosphere;
Stage #2: C9H6F3NO2 In isopropyl alcohol at 0℃; for 96h; Michael Addition; Schlenk technique; Inert atmosphere; enantioselective reaction;
92%
acetylpyrazine
22047-25-2

acetylpyrazine

C18H12ClF3N2O4S

C18H12ClF3N2O4S

(S)-3-(5-chloro-1-tosyl-1H-indol-3-yl)-4,4,4-trifluoro-3-(nitromethyl)-1-(pyrazin-2-yl)butan-1-one

(S)-3-(5-chloro-1-tosyl-1H-indol-3-yl)-4,4,4-trifluoro-3-(nitromethyl)-1-(pyrazin-2-yl)butan-1-one

Conditions
ConditionsYield
With C28H29N3O; cobalt(II) aceylacetonate In tert-butyl methyl ether at 20℃; Michael Addition; Schlenk technique; Inert atmosphere; enantioselective reaction;92%
acetylpyrazine
22047-25-2

acetylpyrazine

5-Iodoisophthalic dihydrazide
193614-92-5

5-Iodoisophthalic dihydrazide

C20H17IN8O2

C20H17IN8O2

Conditions
ConditionsYield
With acetic acid In ethanol Reflux;92%
acetylpyrazine
22047-25-2

acetylpyrazine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

3-(N,N-dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one
866000-17-1

3-(N,N-dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one

Conditions
ConditionsYield
With guanidineacetic acid at 100℃; for 1h;91%
With L-proline In neat (no solvent) at 80℃; for 1.5h;90%
With triethylamine at 110℃; for 16h;81%
acetylpyrazine
22047-25-2

acetylpyrazine

trans-1-(4-fluorophenyl)-2-nitro-ethene
706-08-1, 5153-69-5

trans-1-(4-fluorophenyl)-2-nitro-ethene

(R)-3-(4-fluorophenyl)-4-nitro-1-(pyrazin-2-yl)butan-1-one
1433955-80-6

(R)-3-(4-fluorophenyl)-4-nitro-1-(pyrazin-2-yl)butan-1-one

Conditions
ConditionsYield
With nickel(II) acetate tetrahydrate; (4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole) In isopropyl alcohol at 20℃; for 3h; Michael Addition; Inert atmosphere; enantioselective reaction;91%
2-Aminonicotinaldehyde
7521-41-7

2-Aminonicotinaldehyde

acetylpyrazine
22047-25-2

acetylpyrazine

2-(pyrazin-2-yl)-1,8-naphthyridine
1338090-17-7

2-(pyrazin-2-yl)-1,8-naphthyridine

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 60℃;91%
With potassium hydroxide In methanol at 60℃; Inert atmosphere; Schlenk technique; Reflux;85%
acetylpyrazine
22047-25-2

acetylpyrazine

2,5-dihydroxybenzohydrazide
15791-90-9

2,5-dihydroxybenzohydrazide

N1-(2,5-dihydroxybenzoyl)-N2-[1-(2-pyrazinyl)ethylidene]hydrazine

N1-(2,5-dihydroxybenzoyl)-N2-[1-(2-pyrazinyl)ethylidene]hydrazine

Conditions
ConditionsYield
With acetic acid In ethanol for 1h; Reflux;91%
acetylpyrazine
22047-25-2

acetylpyrazine

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

malononitrile
109-77-3

malononitrile

2-amino-4-(3,4-dimethoxyphenyl)-6-(pyrazin-2-yl)nicotinonitrile

2-amino-4-(3,4-dimethoxyphenyl)-6-(pyrazin-2-yl)nicotinonitrile

Conditions
ConditionsYield
With ammonium acetate In ethanol Reflux;91%
acetylpyrazine
22047-25-2

acetylpyrazine

5-methoxy isophthaloyl hydrazide
23341-07-3

5-methoxy isophthaloyl hydrazide

C21H20N8O3

C21H20N8O3

Conditions
ConditionsYield
With acetic acid In ethanol Reflux;91%
acetylpyrazine
22047-25-2

acetylpyrazine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

3-dimethylamino-1-(3-pyrazinyl)-2-propene-1-one
111781-53-4

3-dimethylamino-1-(3-pyrazinyl)-2-propene-1-one

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 20h; Inert atmosphere; Schlenk technique;90.2%
In xylene Heating;73%
In methanol for 10h; Reflux;38%
for 19h; Heating / reflux;
Reflux;
acetylpyrazine
22047-25-2

acetylpyrazine

C10H5F6NO2

C10H5F6NO2

(S)-4,4,4-trifluoro-3-(4-(trifluoromethyl)phenyl)-3-(nitromethyl)-1-(pyrazin-2-yl)butan-1-one

(S)-4,4,4-trifluoro-3-(4-(trifluoromethyl)phenyl)-3-(nitromethyl)-1-(pyrazin-2-yl)butan-1-one

Conditions
ConditionsYield
Stage #1: acetylpyrazine With bis(acetylacetonate)nickel(II); (S,S)-2,2'-isopropylidenebis(4-phenyl-2-oxazoline) In isopropyl alcohol at 0℃; for 0.5h; Michael Addition; Schlenk technique; Inert atmosphere;
Stage #2: C10H5F6NO2 In isopropyl alcohol at 0℃; Michael Addition; Schlenk technique; Inert atmosphere; enantioselective reaction;
90%
pyridine
110-86-1

pyridine

acetylpyrazine
22047-25-2

acetylpyrazine

N-{1-pyrazinyl-1-oxo-2-ethyl}pyridinium iodide

N-{1-pyrazinyl-1-oxo-2-ethyl}pyridinium iodide

Conditions
ConditionsYield
With iodine at 110℃; for 3h;88%
With iodine for 1h; Reflux;82%
With iodine at 90℃; for 1.5h;48%
acetylpyrazine
22047-25-2

acetylpyrazine

benzil dihydrazone
4702-78-7

benzil dihydrazone

N',N'-bis[1-(pyrazine-2-yl)ethylidene]benzil dihydrazone

N',N'-bis[1-(pyrazine-2-yl)ethylidene]benzil dihydrazone

Conditions
ConditionsYield
for 5h; Heating;87%

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