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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

4-(4-FLUOROBENZOYL)-3-(HYDROXYMETHYL)BENZONITRILE

Cas:260371-16-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Manufacturers

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

260371-16-2

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Chemlyte Solutions

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Other

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile 260371-16-2

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-(4-fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Other

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Cas:260371-16-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

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Sichuan WeiKeqi Biological Technology Co., Ltd.

High purity, competitive price! Providing HPLC, MS, HNMR, COA. In stock! Sichuan Weikeqi Biological Technology CO., LTD. was established in 2006. We are located in chengdu city, sichuan province, a professional company engaged in researching,

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Cas:260371-16-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Pure Chemistry Scientific Inc.

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile Application:80074892

4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Cas:260371-16-2

Min.Order:1 Gram

FOB Price: $500.0

Type:Trading Company

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Shanghai PotentPharm Science and Technology Co.,Ltd

1 good quality, better price and bettter service;2 Timely delivery;3 100% refunded if parcel is not delivered or poor quality.We will try to satisfy you upon receipt of your reply. I hope that we can become a long-term cooperative partner. Applicatio

4-(4-Fluorobenzoyl)-3-(hydroxyMethyl)benzonitrile

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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Shenzhen Sumshine Biotech Co., Ltd.

1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

Citalopram Impurity 19

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

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NovaChemistry

High purity Application:Pharmaceutical intermediates, Material synthesis and analyzing the expectant ingredients

Citalopram Related Compound VI

Cas:260371-16-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile
82104-74-3

1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile

4-flourophenylmagnesium bromide
352-13-6

4-flourophenylmagnesium bromide

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Conditions
ConditionsYield
Stage #1: 1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile; 4-flourophenylmagnesium bromide In tetrahydrofuran; 1,2-dimethoxyethane at -10℃; for 3.5h;
Stage #2: With water; ammonium chloride In tetrahydrofuran; 1,2-dimethoxyethane at 20℃; for 0.0833333h;
86.2%
In tetrahydrofuran at 0 - 5℃; for 5h; Solvent; Temperature;85%
Stage #1: 1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile; 4-flourophenylmagnesium bromide In tetrahydrofuran; dichloromethane at -6 - -2℃;
Stage #2: With water; ammonium chloride In tetrahydrofuran; dichloromethane
In tetrahydrofuran; toluene at -4 - -2℃; Product distribution / selectivity;
1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile
82104-74-3

1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile

1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Conditions
ConditionsYield
Stage #1: 1-Bromo-4-fluorobenzene With magnesium In tetrahydrofuran Reflux; Inert atmosphere;
Stage #2: 1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere;
63%
1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile
82104-74-3

1-oxo-1,3-dihydro-isobenzofuran-5-carbonitrile

4-flourophenylmagnesium bromide
352-13-6

4-flourophenylmagnesium bromide

A

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

B

4-(bis(4-fluorophenyl)hydroxymethyl)-3-(hydroxymethyl)benzonitrile
762266-07-9

4-(bis(4-fluorophenyl)hydroxymethyl)-3-(hydroxymethyl)benzonitrile

Conditions
ConditionsYield
In tetrahydrofuran; water at -10 - -5℃; for 3h;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

dihydroxy-methyl-borane
13061-96-6

dihydroxy-methyl-borane

C27H28BFN2O3

C27H28BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; under 45.0045 - 52.5053 Torr; for 1.5h; Product distribution / selectivity;91%
In toluene at 25 - 65℃; under 7.50075 - 82.5083 Torr; for 1 - 3h; Product distribution / selectivity; Molecular sieve;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

4-(4-fluorobenzoyl)-3-(tert-butyldimethylsiloxymethyl)benzonitrile
1370643-21-2

4-(4-fluorobenzoyl)-3-(tert-butyldimethylsiloxymethyl)benzonitrile

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 10 - 15℃; for 0.5h;84%
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

4-(bis(4-fluorophenyl)hydroxymethyl)-3-(hydroxymethyl)benzonitrile
762266-07-9

4-(bis(4-fluorophenyl)hydroxymethyl)-3-(hydroxymethyl)benzonitrile

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile
207680-98-6

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile; 4-(bis(4-fluorophenyl)hydroxymethyl)-3-(hydroxymethyl)benzonitrile With sodium hydroxide; sodium tetrahydroborate In tetrahydrofuran; water at 0 - 15℃; for 0.5h;
Stage #2: With phosphoric acid In water for 2h; Heating / reflux;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile
207680-98-6

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol; toluene at 10 - 15℃; for 2h;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

boron complex VB

boron complex VB

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 5 - 25℃; for 7 - 9h;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

3-(N,N-dimethylamino)propylmagnesium chloride
19070-16-7

3-(N,N-dimethylamino)propylmagnesium chloride

4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
103146-25-4

4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile

Conditions
ConditionsYield
In tetrahydrofuran; 1,1-Dibromoethane; dichloromethane; toluene at -5 - 5℃; for 3 - 4h;
Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.75h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

diisopropoxymethylborane
86595-27-9

diisopropoxymethylborane

A

C27H28BFN2O3

C27H28BFN2O3

B

isopropyl alcohol
67-63-0

isopropyl alcohol

Conditions
ConditionsYield
In toluene at 20 - 70℃; under 45.0045 - 52.5053 Torr; for 0.866667 - 1.03333h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

(S)-1-dimethylamino-2-propanol
53636-17-2

(S)-1-dimethylamino-2-propanol

diisopropoxymethylborane
86595-27-9

diisopropoxymethylborane

C21H24BFN2O3

C21H24BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 45℃; for 0.75h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

diisopropoxymethylborane
86595-27-9

diisopropoxymethylborane

C35H33BFN3O3

C35H33BFN3O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.75h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

(1S,2R)-(+)-N-methylephedrine
42151-56-4

(1S,2R)-(+)-N-methylephedrine

diisopropoxymethylborane
86595-27-9

diisopropoxymethylborane

C27H28BFN2O3

C27H28BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.75h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

(R)-2-dimethylamino-1-phenyl-ethanol
34469-09-5

(R)-2-dimethylamino-1-phenyl-ethanol

diisopropoxymethylborane
86595-27-9

diisopropoxymethylborane

C26H26BFN2O3

C26H26BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.75h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

dihydroxy-methyl-borane
13061-96-6

dihydroxy-methyl-borane

(1S,2R)-(+)-N-methylephedrine
42151-56-4

(1S,2R)-(+)-N-methylephedrine

C27H28BFN2O3

C27H28BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.583333h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

dihydroxy-methyl-borane
13061-96-6

dihydroxy-methyl-borane

(S)-2-dimethylamino-1-phenylethanol
2202-68-8, 2202-69-9, 6853-14-1, 34469-09-5

(S)-2-dimethylamino-1-phenylethanol

C26H26BFN2O3

C26H26BFN2O3

Conditions
ConditionsYield
In toluene at 50℃; under 45.0045 - 52.5053 Torr; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

Trimethylboroxine
823-96-1

Trimethylboroxine

(1S,2R)-(+)-N-methylephedrine
42151-56-4

(1S,2R)-(+)-N-methylephedrine

C27H28BFN2O3

C27H28BFN2O3

Conditions
ConditionsYield
In toluene at 20 - 70℃; for 0.583333h; Product distribution / selectivity;
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

3-(N,N-dimethylamino)propylmagnesium chloride
19070-16-7

3-(N,N-dimethylamino)propylmagnesium chloride

A

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile
207680-98-6

4-[(4-fluoro-phenyl)-hydroxy-methyl]-3-hydroxymethyl-benzonitrile

B

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
488787-59-3

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile

C

(+)-(R)-4-(4-dimethylamino-1-(4'-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile

(+)-(R)-4-(4-dimethylamino-1-(4'-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile With (1S,2R)-(+)-N-methylephedrine In toluene at 20 - 70℃; for 0.75h;
Stage #2: 3-(N,N-dimethylamino)propylmagnesium chloride In tetrahydrofuran; toluene at -80℃; for 0.2h; Product distribution / selectivity;
A n/a
B n/a
C n/a
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

3-(N,N-dimethylamino)propylmagnesium chloride
19070-16-7

3-(N,N-dimethylamino)propylmagnesium chloride

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
488787-59-3

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile With dihydroxy-methyl-borane In toluene at 20 - 70℃; for 0.75h;
Stage #2: 3-(N,N-dimethylamino)propylmagnesium chloride In tetrahydrofuran; toluene at -60℃; for 0.2h; Product distribution / selectivity;
n/a
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

3-(N,N-dimethylamino)propylmagnesium chloride
19070-16-7

3-(N,N-dimethylamino)propylmagnesium chloride

A

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
488787-59-3

(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile

B

(+)-(R)-4-(4-dimethylamino-1-(4'-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile

(+)-(R)-4-(4-dimethylamino-1-(4'-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile With (1S,2R)-(+)-N-methylephedrine In toluene at 20 - 70℃; for 0.75h;
Stage #2: 3-(N,N-dimethylamino)propylmagnesium chloride In tetrahydrofuran; toluene at -80℃; for 0.2h; Product distribution / selectivity;
A n/a
B n/a
4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
260371-16-2

4-(4-fluorobenzoyl)-3-(hydroxymethyl)benzonitrile

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

A

C26H35FN2OSi

C26H35FN2OSi

B

C26H35FN2OSi

C26H35FN2OSi

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1H-imidazole / dichloromethane / 0.5 h / 10 - 15 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 3.5 h / 5 - 60 °C / Inert atmosphere
2.2: 60 °C / Inert atmosphere
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