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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Methylnicotinic acid Manufacturer/High quality/Best price/In stock

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Methyl-Nicotinic Acid supplier in China

Cas:3222-49-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White or off white powder Storage:Store at RT. Package:1k

Rupatadine intermediate 5-Methylnicotinic acid CAS 3222-49-9 supplied by manufacturer

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $400.0 / 500.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-methylnicotinic acid

Cas:3222-49-9

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

CHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis

CAS 3222-49-9 / 5-Methylnicotinic Acid / Pharmaceutical Intermediate

Cas:3222-49-9

Min.Order:1 Gram

FOB Price: $3.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 3222-49-9 with competitive price

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Pharmaceutical Intermediate 5-Methylnicotinic acid CAS 3222-49-9

Cas:3222-49-9

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Methylnicotinic acid 3222-49-9

Cas:3222-49-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

Overview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie

China Biggest Factory & Manufacturer supply 5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $30.0 / 35.0

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $68.0 / 75.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

5-Methylnicotinic acid CAS:3222-49-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

5-Methylnicotinic acid CAS:3222-49-9

Cas:3222-49-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

5-Methylnicotinic acid CAS 3222-49-9

Cas:3222-49-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3222-49-9

Cas:3222-49-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $40.0 / 60.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Methyl-Nicotinic Acid

Cas:3222-49-9

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-methylpyridine-3-carboxylic acid

Cas:3222-49-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5-Methyl-Nicotinic Acid

Cas:3222-49-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermediates Trans

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

3222-49-9 5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Metric Ton

FOB Price: $5000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-Methylnicotinic acid Manufacturer/High quality/Best price/In stock

Cas:3222-49-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

5-Methylnicotinicacid

Cas:3222-49-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Methylnicotinic acid

Cas:3222-49-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

1-(5-methylpyridin-3-yl)ethanone
42972-46-3

1-(5-methylpyridin-3-yl)ethanone

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With sodium hydroxide; bromine In water Ambient temperature;61%
3,5-Lutidine
591-22-0

3,5-Lutidine

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With potassium permanganate In water at 25 - 45℃; for 20h;59.4%
With potassium permanganate In water at 45℃;46%
With potassium permanganate at 45℃; for 20h;41%
With potassium permanganate In water; acetone at 70℃; for 2h; Title compound not separated from byproducts;
3,5-Lutidine
591-22-0

3,5-Lutidine

A

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

B

3,5-Pyridinedicarboxylic acid
499-81-0

3,5-Pyridinedicarboxylic acid

Conditions
ConditionsYield
With potassium permanganate In water 1.) from RT to 43 deg C, 5 h, 2.) 45 deg C, overnight;A 27%
B n/a
3-methylquinoline
612-58-8

3-methylquinoline

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With potassium permanganate Erhitzen des Reaktionsprodukts im Hochvakuum;
3-methyl-5-pentyl-pyridine
112945-08-1

3-methyl-5-pentyl-pyridine

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With potassium permanganate
3-methyl-pyridine-dicarboxylic acid-(2.5)

3-methyl-pyridine-dicarboxylic acid-(2.5)

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With acetic anhydride; acetic acid at 225℃;
5-methyl-pyridine-dicarboxylic acid-(2.3)

5-methyl-pyridine-dicarboxylic acid-(2.3)

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

Conditions
ConditionsYield
With acetic anhydride; acetic acid at 225℃;
3-methylquinoline
612-58-8

3-methylquinoline

water
7732-18-5

water

permanganate

permanganate

A

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

B

5-methyl-pyridine-2,3-dicarboxylic acid
53636-65-0

5-methyl-pyridine-2,3-dicarboxylic acid

methanol
67-56-1

methanol

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

5-methylnicotinic acid methyl ester
29681-45-6

5-methylnicotinic acid methyl ester

Conditions
ConditionsYield
With thionyl chloride at 20℃; for 4h; Concentration; Inert atmosphere; Reflux;98.2%
With thionyl chloride at 60 - 65℃; Inert atmosphere;96%
With thionyl chloride at 82℃; for 6.33333h; Temperature; Concentration;96.5%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

descarboethoxyloratadine
100643-71-8

descarboethoxyloratadine

[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(5-methyl-pyridin-3-yl)-methanone

[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(5-methyl-pyridin-3-yl)-methanone

Conditions
ConditionsYield
With boric acid In toluene Concentration; Reflux;95%
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide for 18h; Ambient temperature;44%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

tert-butyl (S)-(1-(3-aminophenyl)ethyl)carbamate

tert-butyl (S)-(1-(3-aminophenyl)ethyl)carbamate

tert-butyl (S)-(1-(3 -(5-methylnicotinamido)phenyl)ethyl)carbamate

tert-butyl (S)-(1-(3 -(5-methylnicotinamido)phenyl)ethyl)carbamate

Conditions
ConditionsYield
Stage #1: 5-methylnicotinic acid With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.333333h;
Stage #2: tert-butyl (S)-(1-(3-aminophenyl)ethyl)carbamate With N-ethyl-N,N-diisopropylamine at 20℃; for 16h;
92%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

N-methoxy-N,5-dimethylnicotinamide
342602-12-4

N-methoxy-N,5-dimethylnicotinamide

Conditions
ConditionsYield
Stage #1: 5-methylnicotinic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide for 0.5h;
Stage #2: N,O-dimethylhydroxylamine*hydrochloride In N,N-dimethyl-formamide at 20℃; for 16h;
91%
Stage #1: 5-methylnicotinic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1h;
Stage #2: N,O-dimethylhydroxylamine*hydrochloride With pyridine In dichloromethane at 0 - 20℃; for 18h;
87%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

dihydroartemisinin
71939-50-9

dihydroartemisinin

C22H29NO6

C22H29NO6

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 9.5h;86%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

(S)-5-((1-(3-aminophenyl)ethyl)amino)-1-(4-methoxybenzyl)-3-methyl-1.3-dihydro-2H-imidazo[4.5-b]pyrazin-2-one

(S)-5-((1-(3-aminophenyl)ethyl)amino)-1-(4-methoxybenzyl)-3-methyl-1.3-dihydro-2H-imidazo[4.5-b]pyrazin-2-one

(S)-N-(3-(1-((1-(4-methoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyrazin-5-yl)amino)ethyl)phenyl)-5-methylnicotinamide

(S)-N-(3-(1-((1-(4-methoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyrazin-5-yl)amino)ethyl)phenyl)-5-methylnicotinamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h;86%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

N-(4-methyl-3-(piperidin-4-yloxy)phenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoamide trihydrochloride

N-(4-methyl-3-(piperidin-4-yloxy)phenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoamide trihydrochloride

N-(4-methyl-3-((1-(5-methylnicotinoyl)piperidin-4-yl)oxy)-phenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)-benzamide

N-(4-methyl-3-((1-(5-methylnicotinoyl)piperidin-4-yl)oxy)-phenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)-benzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0 - 20℃; for 2h;76%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

A

5-methyl-2-pyridinecarboxamide
20970-77-8

5-methyl-2-pyridinecarboxamide

B

5-methylpyridinylcarboxamide
70-57-5

5-methylpyridinylcarboxamide

Conditions
ConditionsYield
With ammonium chloride In methanol; thionyl chloride; 1,1-dichloroethaneA 73%
B n/a
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

tert-butyl (S)-5-((1-(3-aminophenyl)ethyl)amino)-3-methyl-1H-pyrazolo[3,4-b]pyrazine-1-carboxylate

tert-butyl (S)-5-((1-(3-aminophenyl)ethyl)amino)-3-methyl-1H-pyrazolo[3,4-b]pyrazine-1-carboxylate

tert-butyl (S)-3-methyl-5-((1-(3-(5-methylnicotinamido)phenyl)ethyl)amino)-1H-pyrazolo[3,4-b]pyrazine-1-carboxylate

tert-butyl (S)-3-methyl-5-((1-(3-(5-methylnicotinamido)phenyl)ethyl)amino)-1H-pyrazolo[3,4-b]pyrazine-1-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h;73%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

(S)-N-(1-(3-aminophenyl)ethyl)-6-methylfuro[2,3-b]pyrazin-3-amine

(S)-N-(1-(3-aminophenyl)ethyl)-6-methylfuro[2,3-b]pyrazin-3-amine

(S)-5-methyl-N-(3-(1-((6-methylfuro[2,3-b]pyrazin-3-yl)amino)ethyl)phenyl)nicotinamide hydrochloride salt

(S)-5-methyl-N-(3-(1-((6-methylfuro[2,3-b]pyrazin-3-yl)amino)ethyl)phenyl)nicotinamide hydrochloride salt

Conditions
ConditionsYield
Stage #1: 5-methylnicotinic acid; (S)-N-(1-(3-aminophenyl)ethyl)-6-methylfuro[2,3-b]pyrazin-3-amine With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: With hydrogenchloride In methanol; water
72%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

thiosemicarbazide
79-19-6

thiosemicarbazide

5-(5-methylpyridin-3-yl)-1,3,4-thiadiazol-2-amine

5-(5-methylpyridin-3-yl)-1,3,4-thiadiazol-2-amine

Conditions
ConditionsYield
With polyphosphoric acid at 140℃; for 1h;71%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

C12H16N2O2
1035211-30-3

C12H16N2O2

C19H21N3O3

C19H21N3O3

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 70℃;70%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 70℃;70%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

2-(1-phenyl-3-(4-fluorophenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazole

2-(1-phenyl-3-(4-fluorophenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazole

(2-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)(5-methylpyridin-3-yl)methanone

(2-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)(5-methylpyridin-3-yl)methanone

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 4.5h;70%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-butyl N-(5-methylpyridin-3-yl)carbamate
631910-23-1

tert-butyl N-(5-methylpyridin-3-yl)carbamate

Conditions
ConditionsYield
With diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine at 80℃;67%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

N-ethyl-N,N-diisopropylamine
7087-68-5

N-ethyl-N,N-diisopropylamine

tert-butyl N-(5-methylpyridin-3-yl)carbamate
631910-23-1

tert-butyl N-(5-methylpyridin-3-yl)carbamate

Conditions
ConditionsYield
With diphenylphosphoranyl azide In ethyl acetate; tert-butyl alcohol67%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

3-aminophenylboronic acid pinacolate
210907-84-9

3-aminophenylboronic acid pinacolate

5-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)nicotinamide

5-methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)nicotinamide

Conditions
ConditionsYield
Stage #1: 5-methylnicotinic acid; 3-aminophenylboronic acid pinacolate With HATU In N,N-dimethyl-formamide at 30℃; for 0.0833333h;
Stage #2: With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 30℃; for 16h;
67%
4-amino-4-cyano-piperidine-1-carboxylic acid tert-butyl ester
331281-25-5

4-amino-4-cyano-piperidine-1-carboxylic acid tert-butyl ester

5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

4-cyano-4-[(5-methyl-pyridine-3-carbonyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester
1084926-72-6

4-cyano-4-[(5-methyl-pyridine-3-carbonyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 40℃;65%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 40℃;65%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

C23H15F3N4

C23H15F3N4

(5-methylpyridin-3-yl)(2-(1-phenyl-3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)methanone

(5-methylpyridin-3-yl)(2-(1-phenyl-3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)methanone

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 4.5h;65%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

5-methylnicotinic acid methyl ester
29681-45-6

5-methylnicotinic acid methyl ester

Conditions
ConditionsYield
In methanol; diethyl ether63%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

N-[(1S)-1-(3-aminophenyl)ethyl]-6-bromopyridin-2-amine
1027256-71-8

N-[(1S)-1-(3-aminophenyl)ethyl]-6-bromopyridin-2-amine

N-(3-{(1S)-1-[(6-bromopyridin-2-yl)amino]ethyl}phenyl)-5-methylnicotinamide
1027253-76-4

N-(3-{(1S)-1-[(6-bromopyridin-2-yl)amino]ethyl}phenyl)-5-methylnicotinamide

Conditions
ConditionsYield
With 4-pyrrolidin-1-ylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 17h;63%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

(4-cyclobutyl-1,4-diazepan-1-yl)(7-azaspiro[3.5]nonan-2-yl)-methanone
1227610-25-4

(4-cyclobutyl-1,4-diazepan-1-yl)(7-azaspiro[3.5]nonan-2-yl)-methanone

(4-cyclobutyl-1,4-diazepan-1-yl)(7-(5-methylnicotinoyl)-7-azaspiro[3.5]nonan-2-yl)methanone
1227609-95-1

(4-cyclobutyl-1,4-diazepan-1-yl)(7-(5-methylnicotinoyl)-7-azaspiro[3.5]nonan-2-yl)methanone

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 72h;62%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

2-(1-phenyl-3-(4-methylphenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazole

2-(1-phenyl-3-(4-methylphenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazole

C30H23N5O

C30H23N5O

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 4.5h;61%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

NADP
53-59-8

NADP

5-methyl-NAADP

5-methyl-NAADP

Conditions
ConditionsYield
With Aplysia californica ADP-ribosyl cyclase; sodium hydroxide In water at 37℃; for 2.5h; pH=4;59%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

(S)-N-(1-(3-aminophenyl)ethyl)-2-ethyl-2H-pyrazolo[3,4-b]pyrazin-6-amine

(S)-N-(1-(3-aminophenyl)ethyl)-2-ethyl-2H-pyrazolo[3,4-b]pyrazin-6-amine

(S)-N-(3-(1-((2-ethyl-2H-pyrazolo[3.4-b]pyrazin-6-yl)amino)ethyl)phenyl)-5-methylnicotinamide hydrochloride salt

(S)-N-(3-(1-((2-ethyl-2H-pyrazolo[3.4-b]pyrazin-6-yl)amino)ethyl)phenyl)-5-methylnicotinamide hydrochloride salt

Conditions
ConditionsYield
Stage #1: 5-methylnicotinic acid; (S)-N-(1-(3-aminophenyl)ethyl)-2-ethyl-2H-pyrazolo[3,4-b]pyrazin-6-amine With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 3h;
Stage #2: With hydrogenchloride In 1,4-dioxane
57%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

lead(II) acetate trihydrate
6080-56-4

lead(II) acetate trihydrate

[Pb(5-methylnicotinate)2]n

[Pb(5-methylnicotinate)2]n

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 125℃; for 48h; High pressure;56%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

lead(II) nitrate

lead(II) nitrate

[Pb(5-methylnicotinate)(NO3)]n

[Pb(5-methylnicotinate)(NO3)]n

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 125℃; for 48h; High pressure;51%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

(4-cyclobutylpiperazin-1-yl)(7-azaspiro[3.5]nonan-2-yl)methanone
1227610-21-0

(4-cyclobutylpiperazin-1-yl)(7-azaspiro[3.5]nonan-2-yl)methanone

(4-cyclobutylpiperazin-1-yl)(7-(5-methylnicotinoyl)-7-azaspiro[3.5]nonan-2-yl)methanone
1227609-74-6

(4-cyclobutylpiperazin-1-yl)(7-(5-methylnicotinoyl)-7-azaspiro[3.5]nonan-2-yl)methanone

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide49.2%
5-methylnicotinic acid
3222-49-9

5-methylnicotinic acid

C14H12ClF3N4O

C14H12ClF3N4O

N-[(7S)-5-[3-chloro-4-(trifluoromethyl)phenyl]-7-methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-3-yl]-5-methylpyridine-3-carboxamide

N-[(7S)-5-[3-chloro-4-(trifluoromethyl)phenyl]-7-methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-3-yl]-5-methylpyridine-3-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h;47%
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