Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:35846-53-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:35846-53-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Maytansine CAS:35846-53-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:35846-53-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
maitansine CAS: 35846-53-8 Specification cas no.: 474645-27-7 assay: 99%min molecular formula: c39h67n5o7 molecular weight: 717.97858 character: white powder storage store at -
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Product Name: maitansine Synonyms: maitansine;Maytansine;NSC 153858 CAS: 35846-53-8 MF: C34H46ClN3O10 MW: 692.201 EINECS: 252-754-7 Product Categories: Mol File: 35846-53-8.mol Uses Antineoplastic. Appearance:Solid Storage:Store
Cas:35846-53-8
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryAppearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:By Sea/Air/Courier Port:Qingdao
Cas:35846-53-8
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:35846-53-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:35846-53-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:35846-53-8
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:35846-53-8
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryHigh quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality produc
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:35846-53-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:35846-53-8
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:35846-53-8
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryWe produce carbomer by our own factory,carbomer 940 is our best seller.It is used for cosmetic and medical.And we also become agent for lubrizol.Our carbomer 940 get high viscosity and good transparency.The price will depond on the market,surely supp
Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as:
Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals
1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re
1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in
maytansine 9-O-methyl ether
maytansine
Conditions | Yield |
---|---|
With pyridine hydrochloride In tetrahydrofuran at 25℃; for 14h; | 95% |
4-deoxymaytansinol
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 2: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 3: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 4: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
(3E,5E,14E)-(7R,8S,12S,13S,16S)-21-Chloro-16-hydroxy-7,8,22-trimethoxy-3,13,15,19-tetramethyl-11-oxa-9,19-diaza-tricyclo[18.3.1.18,12]pentacosa-1(24),3,5,14,20,22-hexaene-10,18-dione
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 2: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 3: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
C36H56ClNO5S2Si
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 1.) pyridine, 2.) aq. ammonium hydroxide / 1.) 27 deg C, 20 min, 2.) tert-butyl alcohol, 27 deg C, 2 h 2: mercuric chloride, aq. calcium carbonate / acetonitrile / 12 h / 25 °C 3: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C 4: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 5: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 6: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 7: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
3-O-(tert-butyldimethylsilyl)-4,5-deoxymaytansinol
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C 2: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 3: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 4: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 5: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
C37H57ClN2O6S2Si
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: mercuric chloride, aq. calcium carbonate / acetonitrile / 12 h / 25 °C 2: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C 3: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 4: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 5: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 6: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 1.) 2-propanethiol, boron trifluoride etherate, 2.) silver nitrate, aq. 2,6-lutidine / 1.) methylene chloride, - 78 deg C, 5 min, 2.) THF, 25 deg C, 1.75 h 2: 1.) pyridine, 2.) aq. ammonium hydroxide / 1.) 27 deg C, 20 min, 2.) tert-butyl alcohol, 27 deg C, 2 h 3: mercuric chloride, aq. calcium carbonate / acetonitrile / 12 h / 25 °C 4: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C 5: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 6: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 7: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 8: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: 71 percent / mesitylenesulfonyl chloride, diisopropylethylamine / benzene / 28 h / 40 °C 2: 1.) 2-propanethiol, boron trifluoride etherate, 2.) silver nitrate, aq. 2,6-lutidine / 1.) methylene chloride, - 78 deg C, 5 min, 2.) THF, 25 deg C, 1.75 h 3: 1.) pyridine, 2.) aq. ammonium hydroxide / 1.) 27 deg C, 20 min, 2.) tert-butyl alcohol, 27 deg C, 2 h 4: mercuric chloride, aq. calcium carbonate / acetonitrile / 12 h / 25 °C 5: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C 6: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C 7: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C 8: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 9: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
(-)-maytansinol
maytansine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C 2: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C View Scheme |
methanol
maytansine
(3E,5E,7R,84Ξ,86S)-12c-(N-acetyl-N-methyl-L-alanyloxy)-14-chloro-10t,11c-epoxy-15,7r,84-trimethoxy-3,9c,11t,15-tetramethyl-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione
Conditions | Yield |
---|---|
With trifluoroacetic acid In benzene Ambient temperature; |
1-thiopropane
maytansine
(3E,5E,7R,84Ξ,86S)-12c-(N-acetyl-N-methyl-L-alanyloxy)-14-chloro-10t,11c-epoxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-84-propylsulfanyl-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione
Conditions | Yield |
---|---|
With trifluoroacetic acid In dichloromethane for 15h; Ambient temperature; |
ethanol
maytansine
(3E,5E,7R,84Ξ,86S)-12c-(N-acetyl-N-methyl-L-alanyloxy)-14-chloro-10t,11c-epoxy-84-ethoxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione
Conditions | Yield |
---|---|
With trifluoroacetic acid In benzene Ambient temperature; |
maytansine
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline
Conditions | Yield |
---|---|
With potassium phosphate; (2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1 ‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl)]palladium(II) methanesulfonate In tetrahydrofuran; water at 20℃; for 17h; Inert atmosphere; Sealed tube; | 17.3 mg |
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