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Cas:35853-41-9
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryHigh quality 2,8-Bis(trifluoromethyl)-4-quinolinol Cas 35853-41-9 with low price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates
Cas:35853-41-9
Min.Order:10 Kilogram
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inquiryhe company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:White or
Cas:35853-41-9
Min.Order:1 Kilogram
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:35853-41-9
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:35853-41-9
Min.Order:1 Gram
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:35853-41-9
Min.Order:1 Kilogram
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Type:Trading Company
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen
Cas:35853-41-9
Min.Order:1 Kilogram
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inquiryProduct name:2,8-Bis(trifluoromethyl)-4-quinolinol CAS:35853-41-9 Molecular Formula:C11H5F6NO Molecular Weight:281.15 EINECS:252-762-0 Purity:99% Product name:2,8-Bis(trifluoromethyl)-4-quinolinol CAS:35853-41-9
Cas:35853-41-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Liquid Storage:Store in sealed containers at cool & dry plac
Cas:35853-41-9
Min.Order:100 Gram
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Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:35853-41-9
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryProduct Name: 2,8-Bis(trifluoromethyl)-4-quinolinol CAS: 35853-41-9 MF: C11H5F6NO MW: 281.15 EINECS: 252-762-0 Mol File: 35853-41-9.mol 2,8-Bis(trifluoromethyl)-4-quinolinol Structure 2,8-Bis(trifluoromethyl)-4-quinolinol Chemical
Cas:35853-41-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry2,8-Bis(trifluoromethyl)-4-quinolinol CAS:35853-41-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qua
Cas:35853-41-9
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:35853-41-9
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:35853-41-9
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:35853-41-9
Min.Order:0
Negotiable
Type:Manufacturers
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:35853-41-9
Min.Order:0 Metric Ton
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Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:35853-41-9
Min.Order:0
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Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:35853-41-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:light grey powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Intermediates, etc. Tr
Cas:35853-41-9
Min.Order:100 Gram
Negotiable
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:35853-41-9
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
Cas:35853-41-9
Min.Order:0
Negotiable
Type:Manufacturers
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Cas:35853-41-9
Min.Order:1 Kilogram
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Type:Other
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier
Cas:35853-41-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in your re
Cas:35853-41-9
Min.Order:0
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Type:Lab/Research institutions
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Cas:35853-41-9
Min.Order:0
Negotiable
Type:Manufacturers
inquiryTAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
Cas:35853-41-9
Min.Order:0
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Type:Manufacturers
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:35853-41-9
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Type:Lab/Research institutions
inquiryethyl 4,4,4-trifluoroacetoacetate
2-(trifluoromethyl)benzenamine
2,8-bis(trifluoromethyl)quinolin-4-ol
Conditions | Yield |
---|---|
With polyphosphoric acid at 150℃; for 3h; | 91% |
With polyphosphoric acid at 150℃; | 77% |
With polyphosphoric acid at 20 - 120℃; for 2h; Inert atmosphere; | 75% |
A
2,8-bis(trifluoromethyl)quinolin-4-ol
B
2,8-bis(trifluoromethyl)-4-quinoline carboxaldehyde
C
2,8-bis-(trifluoromethyl)-quinoline-4-carboxylic acid
Conditions | Yield |
---|---|
With sodium hydroxide; potassium dihydrogenphosphate; oxygen In methanol; water for 0.583333h; pH=7.4; Kinetics; Quantum yield; Further Variations:; pH-values; Reagents; Solvents; O2 conc., ionic strength, buffer conc., addition of scavengers; Decomposition; Irradiation; |
2,8-bis(trifluoromethyl)quinolin-4-ol
Conditions | Yield |
---|---|
With water-d2; sulfuric acid-d2 In iso-butanol at 150 - 200℃; for 4h; | 99% |
2,8-bis(trifluoromethyl)quinolin-4-ol
(2,8-bis-trifluoromethyl)-4-bromoquinoline
Conditions | Yield |
---|---|
With phosphorus(V) oxybromide | 99% |
With phosphorus(V) oxybromide at 120℃; for 5h; Inert atmosphere; | 98% |
With phosphorus(V) oxybromide at 140℃; Inert atmosphere; | 98% |
2,8-bis(trifluoromethyl)quinolin-4-ol
2,8-bis-(trifluoromethyl)-4-chloro-quinoline
Conditions | Yield |
---|---|
With trichlorophosphate at 80℃; for 4h; | 98% |
With trichlorophosphate at 110℃; for 2h; | 85% |
With trichlorophosphate at 80℃; for 4h; | 82% |
2,8-bis(trifluoromethyl)quinolin-4-ol
1-butyn-4-ol
2,5-bis(trifluoromethyl)-4-(3-butyn-1-yloxy)quinoline
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu reaction; | 97% |
2,8-bis(trifluoromethyl)quinolin-4-ol
methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate
2-[[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]methyl]-4-oxazolecarboxylic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 97% |
2,8-bis(trifluoromethyl)quinolin-4-ol
p-toluenesulfonyl chloride
2,8-bis(trifluoromethyl)quinolin-4-yl 4-methylbenzenesulfonate
Conditions | Yield |
---|---|
With sodium hydroxide In water; acetone at 0℃; pH=11; | 96% |
With sodium hydroxide In water; acetone at 0℃; pH=11; | 96% |
With sodium hydroxide In acetone at 5℃; for 0.5h; pH=11; | 91% |
With sodium hydroxide In acetone at 10℃; for 1h; pH=7.5; Inert atmosphere; | 91% |
3-Bromo-but-1-yne
2,8-bis(trifluoromethyl)quinolin-4-ol
4-(1-methylprop-2-ynyloxy)-2,8-bis(trifluoromethyl)quinoline
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.5h; Reflux; Stage #2: 3-Bromo-but-1-yne In acetone for 14h; Reflux; | 92% |
2,8-bis(trifluoromethyl)quinolin-4-ol
2-chloromethylpyridine hydrochloride
4-(2-pyridylmethoxy)-2,8-bis(trifluoromethyl)quinoline
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide; toluene at 110℃; for 20h; | 90% |
2,8-bis(trifluoromethyl)quinolin-4-ol
ethyl bromoacetate
2-[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]acetic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: ethyl bromoacetate With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 90% |
2,8-bis(trifluoromethyl)quinolin-4-ol
cyanomethyl bromide
2-[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]acetonitrile
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: cyanomethyl bromide With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 90% |
2,8-bis(trifluoromethyl)quinolin-4-ol
chloroacetic acid ethyl ester
2-[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]acetic acid ethyl ester
Conditions | Yield |
---|---|
With sodium carbonate; potassium iodide at 80℃; for 2h; | 89% |
2,8-bis(trifluoromethyl)quinolin-4-ol
Ethyl 4-(bromomethyl)benzoate
4-[[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]methyl]benzoic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: Ethyl 4-(bromomethyl)benzoate With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 86% |
Conditions | Yield |
---|---|
In acetone for 3h; Reflux; | 85% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 3h; Reflux; | 84.97% |
2,8-bis(trifluoromethyl)quinolin-4-ol
ethyl 6-(hydroxymethyl)pyridine-2-carboxylate
6-[[[2,8-bis(trifluoromethyl)-4-quinolinyl]oxy]methyl]-2-pyridinecarboxylic acid ethyl ester
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 20℃; Mitsunobu reaction; | 81% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 3h; Reflux; | 79% |
5-Chloromethyl-furan-2-carboxylic acid ethyl ester
2,8-bis(trifluoromethyl)quinolin-4-ol
5-[[[2,6-bis(trifluoromethyl)-4-quinolinyl]oxy]methyl]-2-furancarboxylic ethyl ester
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: 5-Chloromethyl-furan-2-carboxylic acid ethyl ester With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 75% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone Reflux; | 74.23% |
2,8-bis(trifluoromethyl)quinolin-4-ol
Ethyl 2-bromopropionate
2-(2,8-bis-trifluoromethyl-quinolin-4-yloxy)-propionic acid ethyl ester
Conditions | Yield |
---|---|
With sodium carbonate In N,N-dimethyl-formamide at 45℃; for 1h; | 74% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 3h; Reflux; | 74% |
2,8-bis(trifluoromethyl)quinolin-4-ol
4-bromomethylphenylboronic acid pinacol ester
4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyloxy]-2,8-bis-trifluoromethyl-quinoline
Conditions | Yield |
---|---|
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; | 73% |
2,8-bis(trifluoromethyl)quinolin-4-ol
2-(bromomethyl)-5-nitrofuran
4-[(5-nitro)-2-furanylmethoxy]-2,8-bis(trifluoromethyl)quinoline
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: 2-(bromomethyl)-5-nitrofuran With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 71% |
2,8-bis(trifluoromethyl)quinolin-4-ol
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol; chloroacyl chloride In acetone for 3h; Reflux; Stage #2: amino With potassium carbonate In ethanol for 3h; Reflux; | 67.84% |
Conditions | Yield |
---|---|
Stage #1: (E)-3-phenylacrylic acid With thionyl chloride at 80℃; for 4h; Stage #2: 2,8-bis(trifluoromethyl)quinolin-4-ol With triethylamine at 20℃; for 3.6h; Cooling with ice; | 67% |
2,8-bis(trifluoromethyl)quinolin-4-ol
4-(chloromethyl)thiazole-2-carboxylic acid-ethyl ester
Conditions | Yield |
---|---|
Stage #1: 2,8-bis(trifluoromethyl)quinolin-4-ol With potassium carbonate In acetone for 0.25h; Reflux; Stage #2: 4-(chloromethyl)thiazole-2-carboxylic acid-ethyl ester With potassium iodide In acetone for 2h; Williamson synthesis; Reflux; | 58% |
2,8-bis(trifluoromethyl)quinolin-4-ol
4-methoxy-2,8-bis(trifluoromethyl)quinoline
Conditions | Yield |
---|---|
With potassium carbonate at 30℃; for 12h; | 52.68% |
2,8-bis(trifluoromethyl)quinolin-4-ol
trifluoromethylsulfonic anhydride
Conditions | Yield |
---|---|
With lithium hydroxide In water; toluene at 0 - 20℃; | 50% |
With lithium hydroxide In water; toluene at 0 - 20℃; for 3h; | 50% |
With lithium hydroxide In water; toluene at 0 - 20℃; for 3h; | 50% |
2,8-bis(trifluoromethyl)quinolin-4-ol
2-bromo-N-(3,5-dimethylphenyl)acetamide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; | 50% |
2,8-bis(trifluoromethyl)quinolin-4-ol
methyl iodide
4-methoxy-2,8-bis(trifluoromethyl)quinoline
Conditions | Yield |
---|---|
With potassium carbonate In acetone at 20℃; for 20h; | 50% |
With potassium carbonate In acetone for 12h; Reflux; |
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