Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(S)-HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

Cas:3705-27-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CYCLO(-GLY-PRO) CAS 3705-27-9

Cas:3705-27-9

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: CYCLO(-GLY-PRO) Synonyms: CYCLO(-GLY-PRO);cyclo(pro-gly);Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-, (8aS)- (9CI);(8AS)-HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;Cyclic (Pro-Gly);(S)-Hexahyd

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best priceCAS 3705-27-9 with competitive price

Cas:3705-27-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)- 3705-27-9

Cas:3705-27-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

CYCLO(-GLY-PRO) CAS:3705-27-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedia

CYCLO(-GLY-PRO) CAS:3705-27-9

Cas:3705-27-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)-

Cas:3705-27-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)-

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cas:3705-27-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

CYCLO(-GLY-PRO)CAS NO.: 3705-27-9

Cas:3705-27-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

shanghai Tauto Biotech Co., Ltd

The quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me

Cyclo(Gly-L-Pro)

Cas:3705-27-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)-

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

CYCLO(-GLY-PRO) CAS 3705-27-9

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

High-quality peptides at competitive prices.Appearance:Powder Storage:Cool dried place Package:PP bags inside,outside aluminium foil bag Application:Intermediate,peptides Transportation:Express, sea, air, land. Port:Shanghai,China

Cyclo(Gly-Pro)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)-

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Cyclo(Gly-Pro)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:10mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any por

CYCLO(-GLY-PRO)

Cas:3705-27-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

N-prolylglycine
2578-57-6

N-prolylglycine

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 200℃; under 12901.3 Torr; for 0.333333h; Microwave irradiation;99%
With Zr6-based UiO-66 metal-organic frameworks at 80℃; for 24h;88%
With 14C2H7N*14H(1+)*2H2O*2O(2-)*2Zr(4+)*O122P4W34(18-) In dimethyl sulfoxide at 70℃; for 24h;76%
Multi-step reaction with 2 steps
1: HCl
2: 105 °C / 0 Torr
View Scheme
(2S)-N-(N-Benzyloxycarbonylglycyl)prolinamide
68385-08-0

(2S)-N-(N-Benzyloxycarbonylglycyl)prolinamide

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 22℃; for 12h;93%
With platinum Hydrogenation;
With hydrogen; palladium on activated charcoal In methanol at 22℃;
C54H59N5O16

C54H59N5O16

A

taxol
33069-62-4

taxol

B

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With trimethylphosphane In tetrahydrofuran; waterA 92%
B n/a
H-Gly-Pro-OH
704-15-4

H-Gly-Pro-OH

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With Zr6-based UiO-66 metal-organic frameworks at 80℃; for 24h;92%
In phenol at 160℃; for 1h;
t-butyloxycarbonyl-glycyl-proline methyl ester
41863-49-4

t-butyloxycarbonyl-glycyl-proline methyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
In water at 130℃; for 4h;90%
Multi-step reaction with 2 steps
1: formic acid
2: toluene; butan-1-ol / Heating
View Scheme
glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

(S)-proline-N-carboxyanhydride
45736-33-2

(S)-proline-N-carboxyanhydride

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Stage #1: glycine ethyl ester hydrochloride; (S)-proline-N-carboxyanhydride With triethylamine In dichloromethane at -78℃; for 6h;
Stage #2: In water for 24h; Heating;
87%
(9aS)-2,3,4,5,7,8,9,9a-Octahydro-1H-pyrrolo<2,1-d><1,2,5>triazepine-1,5-dione
175853-35-7

(9aS)-2,3,4,5,7,8,9,9a-Octahydro-1H-pyrrolo<2,1-d><1,2,5>triazepine-1,5-dione

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With ammonia; sodium In tetrahydrofuran at -60℃; for 0.25h;80%
Multi-step reaction with 2 steps
1: Na, NH3 liq. / -68 °C
View Scheme
N-chloroacetyl-L-proline ethyl ester
96163-74-5

N-chloroacetyl-L-proline ethyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With ammonia In ethanol Ambient temperature;78.2%
Cbz-glycyl-(L)-prolyl benzotriazole
1380332-68-2

Cbz-glycyl-(L)-prolyl benzotriazole

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; for 18h;72%
N-Nitroacetyl-(S)-proline ethyl ester
129222-49-7

N-Nitroacetyl-(S)-proline ethyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With aluminium amalgam In ethanol at 30℃; for 8h;70%
[(pyrrolidine-2-carbonyl)-amino]acetic acid methyl ester trifluoroacetate

[(pyrrolidine-2-carbonyl)-amino]acetic acid methyl ester trifluoroacetate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With triethylamine In methanol Heating;65%
With triethylamine In methanol for 16h; Heating / reflux;
With triethylamine In methanol for 16h; Heating / reflux;
With ammonia In methanol at 23℃; for 4h;n/a
H-Pro-Gly-OMe
33256-35-8

H-Pro-Gly-OMe

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
at 110℃; under 0.001 Torr;
With triethylamine In methanol for 14h; Heating / reflux;
With triethylamine In methanol for 6h; Reflux;
With triethylamine In methanol Heating;
H-Pro-Gly-OEt
26347-43-3

H-Pro-Gly-OEt

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
at 105℃; under 0.001 Torr;
With ethanol; triethylamine
at 105℃; under 0.001 Torr;
N-trichloroethoxycarbonylglycyl-L-proline methyl ester
118373-95-8

N-trichloroethoxycarbonylglycyl-L-proline methyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With methanol; zinc Heating;
N-phthaloylglycine chloride
6780-38-7

N-phthaloylglycine chloride

L-proline
147-85-3

L-proline

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With hydrazine hydrate 1.) CHCl3, reflux, 4 h, 2.) CHCl3, EtOH, a) RT, 12 h, b) reflux, 24 h; Yield given. Multistep reaction;
glycyl proline
52208-82-9

glycyl proline

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(2S)-N-(N-Benzyloxycarbonylglycyl)proline methyl ester
66449-90-9

(2S)-N-(N-Benzyloxycarbonylglycyl)proline methyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 22℃;
Multi-step reaction with 2 steps
1: 81 percent / NH3 / methanol / 216 h
2: 93 percent / H2 / 10percent Pd/C / methanol / 12 h / 22 °C
View Scheme
1-glycyl-L-proline ethyl ester

1-glycyl-L-proline ethyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With ethanol
at 105℃; under 0.001 Torr;
H-Pro-Gly-OEt
26347-43-3

H-Pro-Gly-OEt

ethanolic triethylamine

ethanolic triethylamine

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

[((S)-Pyrrolidine-2-carbonyl)-amino]-acetic acid 4-acetylamino-phenyl ester

[((S)-Pyrrolidine-2-carbonyl)-amino]-acetic acid 4-acetylamino-phenyl ester

A

4-acetaminophenol
103-90-2

4-acetaminophenol

B

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With phosphate buffer at 37℃; pH=7.4; Kinetics;
5-glycylprolylglycyclprolyl-9-di(3-sulfonylpropyl)aminobenza[a]phenoxazolium perchlorate

5-glycylprolylglycyclprolyl-9-di(3-sulfonylpropyl)aminobenza[a]phenoxazolium perchlorate

A

(5-amino-benzo[a]phenoxazin-9-ylidene)-bis-(3-sulfo-propyl)-ammonium; perchlorate

(5-amino-benzo[a]phenoxazin-9-ylidene)-bis-(3-sulfo-propyl)-ammonium; perchlorate

B

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

C

H-Gly-Pro-OH
704-15-4

H-Gly-Pro-OH

Conditions
ConditionsYield
With dipeptidyl peptidase IV; HEPES buffer at 37℃; pH=7.4; Enzyme kinetics;
1-(2-bromoacetyl)pyrrolidine-2-carboxylic acid methyl ester
143601-48-3

1-(2-bromoacetyl)pyrrolidine-2-carboxylic acid methyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 57 percent / H2NNH2*H2O / ethanol / 2 h / Heating
2: 80 percent / Na, liq. NH3 / tetrahydrofuran / 0.25 h / -60 °C
View Scheme
Multi-step reaction with 4 steps
1: H2NNH2*H2O / ethanol / Heating
2: ethanol / 1.5 h / Heating
3: Na, NH3 liq. / -68 °C
View Scheme
methyl (2S)-pyrrolidine carboxylate
2577-48-2

methyl (2S)-pyrrolidine carboxylate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: NMM, iso-butyl chloroformate / tetrahydrofuran; dimethylformamide / -40 °C
2: H2NNH2*H2O / ethanol / Heating
3: ethanol / 1.5 h / Heating
4: Na, NH3 liq. / -68 °C
View Scheme
(S)-1-(2-Bromo-acetyl)-pyrrolidine-2-carboxylic acid hydrazide

(S)-1-(2-Bromo-acetyl)-pyrrolidine-2-carboxylic acid hydrazide

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethanol / 1.5 h / Heating
2: Na, NH3 liq. / -68 °C
View Scheme
N-Boc-L-proline
15761-39-4

N-Boc-L-proline

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 58 percent / 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, HOBT monohydrate, Et3N / 24 h / Ambient temperature
2: 100 percent / 1 h / Ambient temperature
3: 65 percent / Et3N / methanol / Heating
View Scheme
(S)-(-)-N-(tert-butoxycarbonyl)prolylglycine methyl ester

(S)-(-)-N-(tert-butoxycarbonyl)prolylglycine methyl ester

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / 1 h / Ambient temperature
2: 65 percent / Et3N / methanol / Heating
View Scheme
L-proline
147-85-3

L-proline

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92.5 percent / SOCl2
2: 77.2 percent / Et3N / benzene / Ambient temperature
3: 78.2 percent / NH3 / ethanol / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: sodium hydrogencarbonate / water / 20 °C
2: isobutyl chloroformate; 4-methyl-morpholine / dichloromethane / 20 °C
3: trifluoroacetic acid / dichloromethane / 20 °C
4: triethylamine / methanol / Heating
View Scheme
ethyl (2S)-pyrrolidine-2-carboxylate
5817-26-5

ethyl (2S)-pyrrolidine-2-carboxylate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77.2 percent / Et3N / benzene / Ambient temperature
2: 78.2 percent / NH3 / ethanol / Ambient temperature
View Scheme
N-carbobenzoxyprolylglycine
2766-18-9

N-carbobenzoxyprolylglycine

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: palladium; acetic acid; aqueous methanol / Hydrogenation
2: HCl
3: 105 °C / 0 Torr
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

C12H18N2O4

C12H18N2O4

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;92%
prenyl bromide
870-63-3

prenyl bromide

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

N-dimethylallyl glycylproline diketopiperazine
111139-36-7

N-dimethylallyl glycylproline diketopiperazine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide84%
trimethoxonium tetrafluoroborate
420-37-1

trimethoxonium tetrafluoroborate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(8aS)-6,7,8,8a-tetrahydro-1-methoxypyrrolo[1,2-a]pyrazin-4(3H)-one
916504-58-0

(8aS)-6,7,8,8a-tetrahydro-1-methoxypyrrolo[1,2-a]pyrazin-4(3H)-one

Conditions
ConditionsYield
In dichloromethane for 24h; Heating;77%
(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(S)-octahydropyrrolo[1,2-a]pyrazine
93643-24-4

(S)-octahydropyrrolo[1,2-a]pyrazine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 27h; Heating;68.9%
With lithium aluminium tetrahydride In tetrahydrofuran for 8h; Heating;55%
With lithium aluminium tetrahydride In tetrahydrofuran for 0.166667h; Heating;
With lithium aluminium tetrahydride In tetrahydrofuran for 3h; Reflux;
Multi-step reaction with 2 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / Reflux
1.2: 3 h / 0 - 20 °C
2.1: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C
View Scheme
1-methoxy-1H-indole-3-carbaldehyde
67282-55-7

1-methoxy-1H-indole-3-carbaldehyde

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(8aS)-2-(3-formyl-1H-indol-2-yl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
155511-91-4

(8aS)-2-(3-formyl-1H-indol-2-yl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
Stage #1: (S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: 1-methoxy-1H-indole-3-carbaldehyde In N,N-dimethyl-formamide at 0 - 20℃; for 6h; regioselective reaction;
67%
formaldehyd
50-00-0

formaldehyd

1-naphtylpiperazine
57536-86-4

1-naphtylpiperazine

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

CSP 2503

CSP 2503

Conditions
ConditionsYield
In methanol; water Mannich reaction; Heating;59%
In ethanol Mannich reaction; Heating;
1-iodo-2,2-dimethyl-1,2-propadiene
31819-97-3

1-iodo-2,2-dimethyl-1,2-propadiene

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

2-(3-methyl-buta-1,2-dienyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

2-(3-methyl-buta-1,2-dienyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With copper(l) iodide; (1S,2S)-N,N'-dimethyl-1,2-diaminocyclohexane; caesium carbonate In N,N-dimethyl-formamide at 75℃; for 16h;58%
formaldehyd
50-00-0

formaldehyd

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

1-(naphthalen-1-yl)-3-(R)-methylpiperazine
439081-68-2

1-(naphthalen-1-yl)-3-(R)-methylpiperazine

(2R,8aS)-2-[[4-(naphth-1-yl)-2-methylpiperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

(2R,8aS)-2-[[4-(naphth-1-yl)-2-methylpiperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

Conditions
ConditionsYield
In methanol; water Mannich reaction; Heating;43%
tert-Butoxybis(dimethylamino)methane
5815-08-7

tert-Butoxybis(dimethylamino)methane

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(8aRS,3Z)-3-[(dimethylamino)methylidene]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
936628-36-3

(8aRS,3Z)-3-[(dimethylamino)methylidene]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 3.5h; Heating;43%
formaldehyd
50-00-0

formaldehyd

1-(3,4-dihydro-2H-1,5-benzodioxepin-6-yl)piperazine
98224-28-3

1-(3,4-dihydro-2H-1,5-benzodioxepin-6-yl)piperazine

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(S)-2-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-6-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

(S)-2-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-6-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

Conditions
ConditionsYield
In methanol; water Mannich reaction; Heating;41%
benzyl chloroformate
501-53-1

benzyl chloroformate

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

benzyl (S)-hexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate
862671-86-1

benzyl (S)-hexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

Conditions
ConditionsYield
Stage #1: (S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione With lithium aluminium tetrahydride In tetrahydrofuran for 14h; Heating / reflux;
Stage #2: With sodium hydrogencarbonate In tetrahydrofuran; water at 0℃;
Stage #3: benzyl chloroformate In tetrahydrofuran; water at 0 - 20℃; for 3h;
41%
Stage #1: (S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione With lithium aluminium tetrahydride In tetrahydrofuran for 16h; Reflux;
Stage #2: benzyl chloroformate With sodium hydrogencarbonate In tetrahydrofuran at 0 - 20℃; for 3h;
formaldehyd
50-00-0

formaldehyd

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

1-(naphthalen-1-yl)-3-(S)-methylpiperazine
439081-70-6

1-(naphthalen-1-yl)-3-(S)-methylpiperazine

(2S,8aS)-2-[[4-(naphth-1-yl)-2-methylpiperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

(2S,8aS)-2-[[4-(naphth-1-yl)-2-methylpiperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine

Conditions
ConditionsYield
In methanol; water Mannich reaction; Heating;36%
1-iodo-propane
107-08-4

1-iodo-propane

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(3R,8aS)-3-Propyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
66511-96-4

(3R,8aS)-3-Propyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With magnesium bromide; lithium diisopropyl amide In tetrahydrofuran at -70℃; for 24h;20%
(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

N-prolylglycine
2578-57-6

N-prolylglycine

Conditions
ConditionsYield
With hydrogenchloride
p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
3705-27-9

(S)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

(S)-2-(4-Methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
118395-74-7

(S)-2-(4-Methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Conditions
ConditionsYield
With sodium hydride DMF; Yield given. Multistep reaction;

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View