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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(S)-METHYL 3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methyl (S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE CAS 37088-66-7

Cas:37088-66-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 8 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

37088-66-7 METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzenepropanoic acid, b-amino-, methyl ester, (bS)-

Cas:37088-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenepropanoic acid, b-amino-, methyl ester, (bS)-

Cas:37088-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenepropanoic acid, b-amino-, methyl ester, (bS)-

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzenepropanoic acid, b-amino-, methyl ester, (bS)-

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Reliable Quality METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fandachem Co.,Ltd, a China-based chemical company, specialize in exporting METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE,cas:37088-66-7, Please contact us by email freely. We are leading exporter in China. If you really need this car

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE,cas:37088-66-7 from fandachem

Cas:37088-66-7

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Methyl (S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Sealed in a cool ,dry and microtherm place , avoid light . Package: 1g/bag, 5g/bag, 10g/bag, 100g/bag, 1kg/bag or as per your request Application:It

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methyl (3S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl (3S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Methyl (3S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

(S)-METHYL 3-AMINO-3-PHENYLPROPANOATEAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:An important raw material and intermediate used in Organic Synthesis, Pharmaceuticals Transpor

(S)-METHYL 3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Methyl (3S)-3-amino-3-phenylpropanoate CAS No.37088-66-7

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear light yellow liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Methyl(3S)-3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

(S)-Methyl 3-amino-3-phenylpropanoate

Cas:37088-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(Z)-3-amino-3-phenylacrylic acid methyl ester
86971-60-0

(Z)-3-amino-3-phenylacrylic acid methyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With di-μ-chloro-bis(1,5-cyclooctadiene)dirhodium; [1'-P(4-CF3Ph)2-2'-(R)-CH(Me)-P(t-Bu)2]ferrocene; hydrogen In 2,2,2-trifluoroethanol at 50℃; under 5171.48 Torr; for 6h;97.6%
With hydrogen; chloro(1,5-cyclooctadiene)rhodium(I) dimer; Josiphos-7 at 50℃; under 5931.67 Torr;92 %Chromat.
methanol
67-56-1

methanol

(S)-3-amino-3-phenylpropanoic acid
614-19-7, 3646-50-2, 13921-90-9, 40856-44-8

(S)-3-amino-3-phenylpropanoic acid

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With thionyl chloride Heating;95%
With hydrogenchloride In water for 16h; Heating / reflux;84%
sulfuric acid for 24h; Heating / reflux;65%
methyl (S)-3-(benzhydrylamino)-3-phenylpropionate
163083-81-6

methyl (S)-3-(benzhydrylamino)-3-phenylpropionate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 25℃; under 760 Torr; for 2.5h; Catalytic hydrogenation;95%
methyl 3-oxo-3-phenylpropionate
614-27-7

methyl 3-oxo-3-phenylpropionate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: methyl 3-oxo-3-phenylpropionate With Ru(OAc)2((R)-dm-segphos); hydrogen; ammonium salicylate In methanol at 85℃; under 22502.3 Torr; for 7h; Autoclave;
Stage #2: With sodium carbonate In water; ethyl acetate for 0.5h; optical yield given as %ee; enantioselective reaction;
84%
With ammonium acetate; hydrogen; Ru(OCOCH3)2((R)-dm-binap) In methanol at 80℃; under 22502.3 Torr; for 16h;40%
Multi-step reaction with 2 steps
1: NH4OAc / methanol / 5 h / Heating
2: 97.6 percent / [(COD)RhCl]2; H2; [1'-P(4-CF3Ph)2-2'-(R)-CH(Me)-P(t-Bu)2]ferrocene / 2,2,2-trifluoro-ethanol / 6 h / 50 °C / 5171.48 Torr
View Scheme
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / methanol / Reflux
2: (S)-(2-(bis(3,3-dimethylphenyl)(hydroxy)methyl)pyrrolidin-1-yl)(pyridin-2-yl)methanone; trichlorosilane / chloroform / 48 h / -30 °C
3: ammonium cerium (IV) nitrate; water / acetonitrile / 0 - 20 °C
View Scheme
(S)-3-((R)-Benzenesulfinylamino)-3-phenyl-propionic acid methyl ester

(S)-3-((R)-Benzenesulfinylamino)-3-phenyl-propionic acid methyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With trifluoroacetic acid In methanol at 0℃; for 2h;73%
(S)-methyl 3-(4-methoxyphenylamino)-3-phenylpropanoate
188488-70-2

(S)-methyl 3-(4-methoxyphenylamino)-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With ammonium cerium (IV) nitrate; water In acetonitrile at 0 - 20℃; optical yield given as %ee;65%
methyl (S)-3-amino-3-phenylpropanoate L-(+)-tartaric acid salt
37088-68-9

methyl (S)-3-amino-3-phenylpropanoate L-(+)-tartaric acid salt

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
In methanol at 20℃; Inert atmosphere; Reflux; Large scale;63%
With sodium hydroxide; water0.30 g
methyl (3S)-3-[(1R)-N-(4-methoxybenzyl)-1-(4-methoxyphenyl)ethylamino]-3-phenylpropanoate
281664-28-6

methyl (3S)-3-[(1R)-N-(4-methoxybenzyl)-1-(4-methoxyphenyl)ethylamino]-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: methyl (3S)-3-[(1R)-N-(4-methoxybenzyl)-1-(4-methoxyphenyl)ethylamino]-3-phenylpropanoate With ammonium cerium(IV) nitrate In water; acetonitrile at 20℃; for 17h;
Stage #2: With hydrogenchloride In methanol at 60℃; for 2h;
60%
methyl 3-amino-3-phenylacrylate
70272-01-4

methyl 3-amino-3-phenylacrylate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With hydrogen; chloroacetic acid; Ru(OCOCH3)2((R)-H8-binap) In methanol at 50℃; under 22502.3 Torr; for 88h; Product distribution / selectivity;39.5%
With hydrogen; Ru(OCOCH3)2((S)-dm-binap) In methanol at 50℃; under 22502.3 Torr; for 88h; Product distribution / selectivity;9%
methyl 3-amino-3-phenylpropanoate
14898-52-3

methyl 3-amino-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate
151133-00-5

tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal 1.) AcOH; 2.) CH3OH; Yield given. Multistep reaction;
methanol
67-56-1

methanol

3-Amino-3-phenylpropionic acid
3646-50-2

3-Amino-3-phenylpropionic acid

A

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

B

methyl (3R)-3-amino-3-phenylpropanoate
37088-67-8

methyl (3R)-3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With hydrogenchloride for 1h; Heating; Yield given;
methyl 3-(2-methoxyphenyl)amino-3-phenylpropionate
287930-00-1

methyl 3-(2-methoxyphenyl)amino-3-phenylpropionate

A

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

B

methyl (3R)-3-amino-3-phenylpropanoate
37088-67-8

methyl (3R)-3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With ammonium peroxydisulfate; silver nitrate In tetrahydrofuran; water; acetonitrile at 60℃; for 4h; Title compound not separated from byproducts;
methyl 3-(2,4-dimethoxyphenyl)amino-3-phenyl-propionate
287930-01-2

methyl 3-(2,4-dimethoxyphenyl)amino-3-phenyl-propionate

A

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

B

methyl (3R)-3-amino-3-phenylpropanoate
37088-67-8

methyl (3R)-3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In water; acetonitrile at 0℃; for 0.666667h; Title compound not separated from byproducts;
(S)-3-Phenyl-succinamic acid methyl ester

(S)-3-Phenyl-succinamic acid methyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With bis-[(trifluoroacetoxy)iodo]benzene In acetonitrile at 20℃; for 1h; Hofmann rearrangement;
(R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2-methoxyphenyl)amino-3-phenylpropionate
288094-28-0

(R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2-methoxyphenyl)amino-3-phenylpropionate

(diazomethyl)-trimethylsilane

(diazomethyl)-trimethylsilane

A

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

B

methyl (3R)-3-amino-3-phenylpropanoate
37088-67-8

methyl (3R)-3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: (R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2-methoxyphenyl)amino-3-phenylpropionate With tetra(n-butyl)ammonium hydroxide In tetrahydrofuran at 0℃; Saponification;
Stage #2: (diazomethyl)-trimethylsilane In methanol at 20℃; Methylation;
Stage #3: With ammonium peroxydisulfate; silver nitrate In tetrahydrofuran; water; acetonitrile at 60℃; Oxidative cleavage; Further stages. Title compound not separated from byproducts.;
(R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2,4-dimethoxyphenyl)amino-3-phenylpropionate

(R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2,4-dimethoxyphenyl)amino-3-phenylpropionate

(diazomethyl)-trimethylsilane

(diazomethyl)-trimethylsilane

A

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

B

methyl (3R)-3-amino-3-phenylpropanoate
37088-67-8

methyl (3R)-3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: (R,R)-2,6-bis(2-isopropylphenyl)-3,5-dimethylphenyl 3-(2,4-dimethoxyphenyl)amino-3-phenylpropionate With tetra(n-butyl)ammonium hydroxide In tetrahydrofuran at 0℃; Saponification;
Stage #2: (diazomethyl)-trimethylsilane In methanol at 20℃; Methylation;
Stage #3: With ammonium cerium(IV) nitrate In water; acetonitrile at 0℃; Oxidative cleavage; Further stages. Title compound not separated from byproducts.;
(S)-(-)-methyl 3-(N-benzylamino)-3-phenylpropanoate

(S)-(-)-methyl 3-(N-benzylamino)-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 16h;
methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate
190189-97-0

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane
(Z)-N-benzylidenebenzylamine N-oxide
77681-22-2, 3376-26-9, 85225-56-5

(Z)-N-benzylidenebenzylamine N-oxide

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Ti-(S)-BINOL-4-tert-butylcatechol / toluene / 24 h / -78 °C
2: Zn; H2SO4 / methanol / 2 h / 60 °C
3: hydrogen / Pd/C / methanol / 16 h / 20 °C
View Scheme
(S)-(-)-methyl 3-(N-tert-butyldimethylsiloxy-N-benzylamino)-3-phenylpropanoate
417725-79-2

(S)-(-)-methyl 3-(N-tert-butyldimethylsiloxy-N-benzylamino)-3-phenylpropanoate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Zn; H2SO4 / methanol / 2 h / 60 °C
2: hydrogen / Pd/C / methanol / 16 h / 20 °C
View Scheme
methyl 3-(N-tert-butyloxycarbonyl-N-benzyl)amino-3-phenylpropionate

methyl 3-(N-tert-butyloxycarbonyl-N-benzyl)amino-3-phenylpropionate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / Pd(OH)2/C / methanol
2: TFA / CH2Cl2
View Scheme
(E)-(4S)-4-(N-benzyl)amino-1-[(1R,2R)-2-hydroxy-1,2-dicyclohexylethyl]oxy-4-phenyl-1-butene
257861-35-1

(E)-(4S)-4-(N-benzyl)amino-1-[(1R,2R)-2-hydroxy-1,2-dicyclohexylethyl]oxy-4-phenyl-1-butene

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: Et3N / tetrahydrofuran / 12 h / 50 °C
2.1: O3 / CH2Cl2 / -78 °C
2.2: dimethyl sulfide / CH2Cl2 / 12 h / -78 - 20 °C
3.1: NaClO2; aq. NaH2PO4 / 2-methyl-propan-2-ol; various solvent(s) / 20 °C
4.1: NaHCO3 / dimethylformamide / 12 h / 20 °C
5.1: H2 / Pd(OH)2/C / methanol
6.1: TFA / CH2Cl2
View Scheme
benzyl-(3-oxo-1-phenyl-propyl)-carbamic acid tert-butyl ester

benzyl-(3-oxo-1-phenyl-propyl)-carbamic acid tert-butyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: NaClO2; aq. NaH2PO4 / 2-methyl-propan-2-ol; various solvent(s) / 20 °C
2: NaHCO3 / dimethylformamide / 12 h / 20 °C
3: H2 / Pd(OH)2/C / methanol
4: TFA / CH2Cl2
View Scheme
methyl (S)-3-(N-tert-butyloxycarbonyl-N-benzyl)amino-3-phenylpropionate
341544-13-6

methyl (S)-3-(N-tert-butyloxycarbonyl-N-benzyl)amino-3-phenylpropionate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / Pd(OH)2/C / methanol
2: TFA / CH2Cl2
View Scheme
3-(benzyl-tert-butoxycarbonyl-amino)-3-phenyl-propionic acid

3-(benzyl-tert-butoxycarbonyl-amino)-3-phenyl-propionic acid

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaHCO3 / dimethylformamide / 12 h / 20 °C
2: H2 / Pd(OH)2/C / methanol
3: TFA / CH2Cl2
View Scheme
Benzyl-[(E)-(S)-4-((1R,2R)-1,2-dicyclohexyl-2-hydroxy-ethoxy)-1-phenyl-but-3-enyl]-carbamic acid tert-butyl ester

Benzyl-[(E)-(S)-4-((1R,2R)-1,2-dicyclohexyl-2-hydroxy-ethoxy)-1-phenyl-but-3-enyl]-carbamic acid tert-butyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: O3 / CH2Cl2 / -78 °C
1.2: dimethyl sulfide / CH2Cl2 / 12 h / -78 - 20 °C
2.1: NaClO2; aq. NaH2PO4 / 2-methyl-propan-2-ol; various solvent(s) / 20 °C
3.1: NaHCO3 / dimethylformamide / 12 h / 20 °C
4.1: H2 / Pd(OH)2/C / methanol
5.1: TFA / CH2Cl2
View Scheme
N-benzylidene-2-methoxy-aniline
5877-56-5

N-benzylidene-2-methoxy-aniline

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: Et2Zn / tetrahydrofuran; hexane / 27 h / -78 °C
2.1: 99 percent / n-Bu4NOH / tetrahydrofuran / 1.5 h / 0 °C
3.1: 99 percent / methanol / 20 °C
4.1: AgNO3; (NH4)2S2O8 / H2O; acetonitrile; tetrahydrofuran / 4 h / 60 °C
View Scheme
(S)-3-(2-Methoxy-phenylamino)-3-phenyl-propionic acid

(S)-3-(2-Methoxy-phenylamino)-3-phenyl-propionic acid

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / methanol / 20 °C
2: AgNO3; (NH4)2S2O8 / H2O; acetonitrile; tetrahydrofuran / 4 h / 60 °C
View Scheme
(S)-3-(2,4-Dimethoxy-phenylamino)-3-phenyl-propionic acid

(S)-3-(2,4-Dimethoxy-phenylamino)-3-phenyl-propionic acid

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / methanol / 20 °C
2: CAN / H2O; acetonitrile / 0.67 h / 0 °C
View Scheme
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(S)-methyl 3-(4-methylphenylsulfonamido)-3-phenylpropanoate
143371-08-8

(S)-methyl 3-(4-methylphenylsulfonamido)-3-phenylpropanoate

Conditions
ConditionsYield
With potassium carbonate In dichloromethane for 0.5h;99%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

(S)-(+)-β-phenyl-β-alanine hydrochloride
83649-47-2

(S)-(+)-β-phenyl-β-alanine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide for 16h; Ambient temperature;98%
5-ethoxy-3,4-dihydro-2H-pyrrole
931-46-4

5-ethoxy-3,4-dihydro-2H-pyrrole

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

(+)-(2S)-2,6,7,8-tetrahydro-2-phenyl-3H-pyrrolo<1,2-a>pyrimidin-4-one
112020-24-3

(+)-(2S)-2,6,7,8-tetrahydro-2-phenyl-3H-pyrrolo<1,2-a>pyrimidin-4-one

Conditions
ConditionsYield
at 125 - 135℃; for 3h;93%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

trifluoro-methanesulfonic acid 3-[(3-cyano-propyl)-naphthalen-2-ylmethyl-amino]-propyl ester

trifluoro-methanesulfonic acid 3-[(3-cyano-propyl)-naphthalen-2-ylmethyl-amino]-propyl ester

methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate
163083-84-9

methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at -78 - 25℃; for 16h; Alkylation;92%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

(S)-3-amino-3-phenylpropanol
82769-76-4

(S)-3-amino-3-phenylpropanol

Conditions
ConditionsYield
With sodium tetrahydroborate; Tetrahydro-furan; compound with trifluoroborane In tetrahydrofuran at 0 - 30℃; for 4h;92%
With sodium tetrahydroborate; sulfuric acid In tetrahydrofuran; diethyl ether Reduction;87%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; Reflux;81%
With sodium tetrahydroborate In tetrahydrofuran72%
tert-butyl hydrogen carbonate
51300-90-4

tert-butyl hydrogen carbonate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate
190189-97-0

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate

Conditions
ConditionsYield
With sodium carbonate In water; ethyl acetate at 20℃; for 24h;91%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate
190189-97-0

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate

Conditions
ConditionsYield
With sodium hydrogencarbonate90%
With sodium hydroxide In tetrahydrofuran at 20℃; for 2h;68%
With triethylamine at 0℃; for 1h;92 mg
With sodium carbonate In tetrahydrofuran; water at 0 - 25℃; for 3h;
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

acetyl chloride
75-36-5

acetyl chloride

methyl (S)-3-acetylamino-3-phenylpropionate
67654-57-3, 105900-59-2, 67654-58-4

methyl (S)-3-acetylamino-3-phenylpropionate

Conditions
ConditionsYield
With triethylamine In chloroform at 0 - 20℃; optical yield given as %ee;90%
3-acetylamino-propionic acid 2,2,2-trifluoro-ethyl ester
917894-26-9

3-acetylamino-propionic acid 2,2,2-trifluoro-ethyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

methyl (S)-3-(3-N-acetylaminopropanoyl)amino-3-phenylpropanoate

methyl (S)-3-(3-N-acetylaminopropanoyl)amino-3-phenylpropanoate

Conditions
ConditionsYield
With Candida antarctica lipase A preparation In diethyl ether at 23℃; for 22h;85%
(R)-3-Acetylamino-2-methyl-propionic acid 2,2,2-trifluoro-ethyl ester
917894-27-0

(R)-3-Acetylamino-2-methyl-propionic acid 2,2,2-trifluoro-ethyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

methyl (S)-3-((R)-3-N-acetylamino-2-methylpropanoyl)amino-3-phenylpropanoate

methyl (S)-3-((R)-3-N-acetylamino-2-methylpropanoyl)amino-3-phenylpropanoate

Conditions
ConditionsYield
With Candida antarctica lipase A preparation In diethyl ether at 23℃; for 75h;85%
(S)-3-Acetylamino-2-methyl-propionic acid 2,2,2-trifluoro-ethyl ester
917894-28-1

(S)-3-Acetylamino-2-methyl-propionic acid 2,2,2-trifluoro-ethyl ester

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

methyl (S)-3-((S)-3-N-acetylamino-2-methylpropanoyl)amino-3-phenylpropanoate

methyl (S)-3-((S)-3-N-acetylamino-2-methylpropanoyl)amino-3-phenylpropanoate

Conditions
ConditionsYield
With Candida antarctica lipase A preparation In diethyl ether at 23℃; for 72h;82%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

4-methyl-N-{3-[(methylsulfonyl)oxy]propyl}benzenesulfonamide
444119-31-7

4-methyl-N-{3-[(methylsulfonyl)oxy]propyl}benzenesulfonamide

methyl (-)-(S)-3-({3-[(4-methylphenylsulfonyl)amino]propyl}amino)-3-phenylpropanoate
444119-32-8

methyl (-)-(S)-3-({3-[(4-methylphenylsulfonyl)amino]propyl}amino)-3-phenylpropanoate

Conditions
ConditionsYield
With triethylamine In acetonitrile for 4h; Heating;79%
benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid
114612-09-8

benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

N-(benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronyl)-β-D-phenylalanine methyl ester
430474-79-6

N-(benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronyl)-β-D-phenylalanine methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 18h;79%
Phenyl triflate
17763-67-6

Phenyl triflate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Methyl (S)-3-anilino-3-phenylpropionate

Methyl (S)-3-anilino-3-phenylpropionate

Conditions
ConditionsYield
With C44H61NO5PPdS; caesium carbonate In 2-methyltetrahydrofuran at 50℃; for 2h; Inert atmosphere;78%
2-methoxy-1-pyrroline
5264-35-7

2-methoxy-1-pyrroline

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

(+)-(2S)-2,6,7,8-tetrahydro-2-phenyl-3H-pyrrolo<1,2-a>pyrimidin-4-one
112020-24-3

(+)-(2S)-2,6,7,8-tetrahydro-2-phenyl-3H-pyrrolo<1,2-a>pyrimidin-4-one

Conditions
ConditionsYield
at 130℃; for 7h;76%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

tert-butyl chloroformate
24608-52-4

tert-butyl chloroformate

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate
190189-97-0

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-3-phenylpropionate

Conditions
ConditionsYield
With sodium carbonate In dichloromethane; water at 20℃; for 3h;76%
With sodium carbonate In dichloromethane; water at 20℃;21.2 g
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

3,4-dihydro-4-hydroxy-1-oxo-4-(2-oxoethyl)isoquinoline-2(1H)-propanenitrile
557077-66-4

3,4-dihydro-4-hydroxy-1-oxo-4-(2-oxoethyl)isoquinoline-2(1H)-propanenitrile

methyl (βS)-β-{{2-[-(2-cyanoethyl)-1,2,3,4-tetrahydro-4-hydroxy-1-oxoisoquinolin-4-yl]ethyl}amino}benzenepropanoate
557077-71-1

methyl (βS)-β-{{2-[-(2-cyanoethyl)-1,2,3,4-tetrahydro-4-hydroxy-1-oxoisoquinolin-4-yl]ethyl}amino}benzenepropanoate

Conditions
ConditionsYield
With hydrogenchloride; sodium cyanoborohydride In methanol at 20℃; for 12h;75%
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

(S)-methyl 3-(ethoxycarbonylamino)-3-phenylpropanoate
1425666-80-3

(S)-methyl 3-(ethoxycarbonylamino)-3-phenylpropanoate

Conditions
ConditionsYield
With sodium carbonate In dichloromethane; water at 20℃; for 3h;72%
With sodium carbonate In dichloromethane; water at 20℃;18 g
(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

(S)-4-phenyl-2-azetidinone
37088-64-5

(S)-4-phenyl-2-azetidinone

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 4h;50%
Stage #1: (3S)-methyl 3-amino-3-phenylpropanoate With dmap; chloro-trimethyl-silane; triethylamine In diethyl ether at 0 - 20℃; for 15h;
Stage #2: With tert-butylmagnesium chloride In diethyl ether at -5 - 20℃; for 12.5h;
31%
Multi-step reaction with 3 steps
1: 98 percent / 1) 40percent aq. NaOH, 2) conc HCl / 16 h / Ambient temperature
2: 99 percent / Et3N / 4 h / 80 °C
3: 1) EtMgBr 2) NH4Cl, 2N HCl / 1) ether, r. t. 3 h, 2) -10 deg C, pH 3
View Scheme
Multi-step reaction with 3 steps
1: 40percent NaOH
2: Et3N
3: EtMgBr
View Scheme
benzyl (1S)-2-hydrazino-1-(hydroxymethyl)-2-oxoethylcarbamate
26582-86-5

benzyl (1S)-2-hydrazino-1-(hydroxymethyl)-2-oxoethylcarbamate

(3S)-methyl 3-amino-3-phenylpropanoate
37088-66-7

(3S)-methyl 3-amino-3-phenylpropanoate

Benzyloxycarbonyl-Ser-L-β-amino-β-phenyl-propionsaeure-methylester

Benzyloxycarbonyl-Ser-L-β-amino-β-phenyl-propionsaeure-methylester

Conditions
ConditionsYield
(i) NaNO2, aq. HCl, AcOH, (ii) /BRN= 5257426/, Et3N, AcOEt, CHCl3; Multistep reaction;

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