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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Isophosphamide

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co. Ltd. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. We export to many countries and area with very competitive price, high quality, good ser

Ifosfamide CAS 3778-73-2

Cas:3778-73-2

Min.Order:1 Gram

FOB Price: $10.0 / 12.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Isophosphamide Cas 3778-73-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder Storage:Store in 2-8℃ Packag

Factory supply Isophosphamide Cas 3778-73-2 with high quality and best price

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $963.0 / 1000.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ifosfamide

Cas:3778-73-2

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Ifosfamide 3778-73-2 Producer

Cas:3778-73-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ifosfamide

Cas:3778-73-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

factory supply 99% Ifosfamide powder

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $25.0 / 500.0

Type:Trading Company

inquiry

Hubei DiBo chemical co., LTD

Name:Ifosfamide CAS NO:3778-73-2 Grade:Medical scientific research and export Molecular formula:C7H15Cl2N2O2P Molecular weight:261.09 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability

Ifosfamide/ CAS:3778-73-2/Ifosfamide raw material/ high-quality

Cas:3778-73-2

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM-- 3778-73-2 -- Isophosphamide in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relations

TIANFUCHEM-- 3778-73-2 -- Isophosphamide in stock

Cas:3778-73-2

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

High Quality CAS 3778-73-2 Ifosfamide Pharmaceutical Grade Ifosfamide Anti Cancer Ifosfamide

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 3778-73-2 with best quality

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

USDMF EDMF are all available! Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the re

Ifosfamide USDMF EDMF

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name Isophosphamide Synonyms IfosfaMide CAS 3778-73-2 CAS: Isophosphamide 3778-73-2 MF: - MW: - EINECS: -

ifosfamid

Cas:3778-73-2

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

Isophosphamide CAS NO 3778-73-2

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem (China) Co.,Ltd is Specia

High-Purity ifosfamide 3778-73-2 (single-impurity: NMT0.5%)

Cas:3778-73-2

Min.Order:100 Gram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Best Prices 99% High Purity Factory Supply Ifosfamide / Isophosphamide / mitoxana

Cas:3778-73-2

Min.Order:10 Gram

FOB Price: $3.1

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Isophosphamide 99%

Cas:3778-73-2

Min.Order:1 Kilogram

FOB Price: $190.0 / 220.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

bilirubin glucuronate CAS:3778-73-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

bilirubin glucuronate CAS:3778-73-2

Cas:3778-73-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Isophosphamide

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Anti-cancer Drug Ifosfamide powder Cas No: 3778-73-2

Cas:3778-73-2

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

Isophosphamide CAS: 3778-73-2 Specification Items Specifications Results Appearance White or almost white crystalline powder Conforms Ionic chloride ≤0.018% <0.018% Chloroform-insoluble p

Factory supply Isophosphamide

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Isophosphamide

Cas:3778-73-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Isophosphamide

Cas:3778-73-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

buy Ifosfamide Isophosphamide China supplier factory manufacturer

Cas:3778-73-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

98.0%min Appearance:White crystalline powder Storage:Storage at room temperature Package:packaged according to the needs of customers Application:used for medicine Transportation:by sea by air express Port:china port

Isophosphamide manufacture 98.0%min usp32

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Ifosfamide CAS 3778-73-2

Cas:3778-73-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Isophosphamide

Cas:3778-73-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Isophosphamide

Cas:3778-73-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Ifosfamide

Cas:3778-73-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

buy Ifosfamide Isophosphamide China supplier factory manufacturer

Cas:3778-73-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Synthetic route

2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
29102-47-4

2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
With hydrogenchloride In chloroform78%
(2S)-2-<(chloroacetyl)amino>-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
84681-45-8

(2S)-2-<(chloroacetyl)amino>-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
With B2F6 In tetrahydrofuran for 12h; Ambient temperature;28%
2-{2-[3-(2-Chloro-ethyl)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-ylamino]-ethoxy}-1,3,5-trimethyl-[1,3,5,2]triazaphosphinane-4,6-dione

2-{2-[3-(2-Chloro-ethyl)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-ylamino]-ethoxy}-1,3,5-trimethyl-[1,3,5,2]triazaphosphinane-4,6-dione

A

ilfosfamide
3778-73-2

ilfosfamide

B

2-chloro-1,3,5-trimethyl-2-oxo-2λ5-[1,3,5,2]triazaphosphinane-4,6-dione
10199-13-0

2-chloro-1,3,5-trimethyl-2-oxo-2λ5-[1,3,5,2]triazaphosphinane-4,6-dione

Conditions
ConditionsYield
With sulfuryl dichloride In dichloromethane at 0℃; for 1h;A 14.8%
B n/a
3-chloroacetyl-2-(2-chloro-ethylamino)-[1,3,2]oxazaphosphinane (S)-2-oxide
72578-72-4

3-chloroacetyl-2-(2-chloro-ethylamino)-[1,3,2]oxazaphosphinane (S)-2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
With diborane In tetrahydrofuran
3-chloroacetyl-2-(2-chloro-ethylamino)-[1,3,2]oxazaphosphinane (R)-2-oxide
72578-71-3

3-chloroacetyl-2-(2-chloro-ethylamino)-[1,3,2]oxazaphosphinane (R)-2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
With diborane In tetrahydrofuran
3-(chloroethyl)-2-chlorooxaazaphosphorinane 2-oxide
81485-04-3

3-(chloroethyl)-2-chlorooxaazaphosphorinane 2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 94.9 percent / Et3N / CH2Cl2 / 5 h / -15 °C
2: 86.5 percent / CH2Cl2 / 24 h / Ambient temperature
3: 14.8 percent / SO2Cl2 / CH2Cl2 / 1 h / 0 °C
View Scheme
Multi-step reaction with 4 steps
1: triethylamine / benzene / 15 h
2: 47 percent / H2 / 10percent Pd/C / ethanol / 96 h / Ambient temperature
3: 50 percent / tetrahydrofuran / 12 h / Ambient temperature
4: 28 percent / B2F6 / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
[3-(2-Chloro-ethyl)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl]-(2-trimethylsilanyloxy-ethyl)-amine
195966-73-5

[3-(2-Chloro-ethyl)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl]-(2-trimethylsilanyloxy-ethyl)-amine

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86.5 percent / CH2Cl2 / 24 h / Ambient temperature
2: 14.8 percent / SO2Cl2 / CH2Cl2 / 1 h / 0 °C
View Scheme
3-(1-Ethylenimino)-1-propanol
31190-87-1

3-(1-Ethylenimino)-1-propanol

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 41 percent / triethylamine, phosphoryl chloride / benzene / 4 h
2: triethylamine / benzene / 15 h
3: 47 percent / H2 / 10percent Pd/C / ethanol / 96 h / Ambient temperature
4: 50 percent / tetrahydrofuran / 12 h / Ambient temperature
5: 28 percent / B2F6 / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
(+)-2-Dechloroethylifosfamide
83802-21-5

(+)-2-Dechloroethylifosfamide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 50 percent / tetrahydrofuran / 12 h / Ambient temperature
2: 28 percent / B2F6 / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
(1'R,2S)-2-<(1'-methylbenzyl)amino>-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
84681-43-6

(1'R,2S)-2-<(1'-methylbenzyl)amino>-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 47 percent / H2 / 10percent Pd/C / ethanol / 96 h / Ambient temperature
2: 50 percent / tetrahydrofuran / 12 h / Ambient temperature
3: 28 percent / B2F6 / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
Dechloroethylcyclophosphamide
36761-83-8

Dechloroethylcyclophosphamide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran
2: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 2 steps
1: tetrahydrofuran
2: B2H6 / tetrahydrofuran
View Scheme
(R)-2-aziridin-1-yl-3-((R)-1-phenyl-ethyl)-[1,3,2]oxazaphosphinane 2-oxide
72578-61-1

(R)-2-aziridin-1-yl-3-((R)-1-phenyl-ethyl)-[1,3,2]oxazaphosphinane 2-oxide

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aq. HCl / diethyl ether
2: H2 / Pd-C / ethanol
3: tetrahydrofuran
4: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 4 steps
1: aq. HCl / diethyl ether
2: H2 / Pd-C / ethanol
3: tetrahydrofuran
4: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 4 steps
1: aq. HCl / diethyl ether
2: H2 / Pd-C / ethanol
3: tetrahydrofuran
4: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 4 steps
1: aq. HCl / diethyl ether
2: H2 / Pd-C / ethanol
3: tetrahydrofuran
4: B2H6 / tetrahydrofuran
View Scheme
(2-chloro-ethyl)-[(S)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine
72578-68-8

(2-chloro-ethyl)-[(S)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2 / Pd-C / ethanol
2: tetrahydrofuran
3: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 3 steps
1: H2 / Pd-C / ethanol
2: tetrahydrofuran
3: B2H6 / tetrahydrofuran
View Scheme
(2-chloro-ethyl)-[(R)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine
72578-67-7

(2-chloro-ethyl)-[(R)-2-oxo-3-((R)-1-phenyl-ethyl)-2λ5-[1,3,2]oxazaphosphinan-2-yl]-amine

ilfosfamide
3778-73-2

ilfosfamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2 / Pd-C / ethanol
2: tetrahydrofuran
3: B2H6 / tetrahydrofuran
View Scheme
Multi-step reaction with 3 steps
1: H2 / Pd-C / ethanol
2: tetrahydrofuran
3: B2H6 / tetrahydrofuran
View Scheme
ilfosfamide
3778-73-2

ilfosfamide

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

Conditions
ConditionsYield
With hydrogenchloride57%
methanol
67-56-1

methanol

ilfosfamide
3778-73-2

ilfosfamide

(+/-)-4-β-methoxyifosfamide
64858-51-1, 64858-52-2

(+/-)-4-β-methoxyifosfamide

(+/-)-4-α-methoxyifosfamide
64858-51-1, 64858-52-2

(+/-)-4-α-methoxyifosfamide

Conditions
ConditionsYield
With tetraethylammonium tosylate Electrochemical reaction; 2.2 F/mol electricity, i=15 mA;A 36%
B 48%
pentan-1-ol
71-41-0

pentan-1-ol

ilfosfamide
3778-73-2

ilfosfamide

(2-chloroethyl)-[3-(2-chloroethyl)-2-oxo-4-pentyloxy-2λ5-[1,3,2]oxazaphosphinan-2-yl]amine

(2-chloroethyl)-[3-(2-chloroethyl)-2-oxo-4-pentyloxy-2λ5-[1,3,2]oxazaphosphinan-2-yl]amine

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile Concentration; Electrochemical reaction;41%
1,7-heptandiol
629-30-1

1,7-heptandiol

ilfosfamide
3778-73-2

ilfosfamide

C14H29Cl2N2O4P

C14H29Cl2N2O4P

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile Electrochemical reaction;27%
1,2-pentanediol
5343-92-0

1,2-pentanediol

ilfosfamide
3778-73-2

ilfosfamide

1-[3-(2-chloroethyl)-2-(2-chloroethylamino)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-4-yloxy]pentan-2-ol
1380481-59-3

1-[3-(2-chloroethyl)-2-(2-chloroethylamino)-2-oxo-2λ5-[1,3,2]oxazaphosphinan-4-yloxy]pentan-2-ol

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile Electrochemical reaction;22%
n-Pent-4-enyl alcohol
821-09-0

n-Pent-4-enyl alcohol

ilfosfamide
3778-73-2

ilfosfamide

(2-chloroethyl)-[3-(2-chloroethyl)-2-oxo-4-pent-4-enyloxy-2λ5-[1,3,2]oxazaphosphinan-2-yl]amine

(2-chloroethyl)-[3-(2-chloroethyl)-2-oxo-4-pent-4-enyloxy-2λ5-[1,3,2]oxazaphosphinan-2-yl]amine

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile Electrochemical reaction;19%
ilfosfamide
3778-73-2

ilfosfamide

A

rac-4-ketoifosfamide
42436-20-4

rac-4-ketoifosfamide

rac-cis-4-hydroperoxyifosfamide
39800-28-7, 59884-18-3, 64858-36-2

rac-cis-4-hydroperoxyifosfamide

rac-trans-4-hydroperoxyifosfamide
39800-28-7, 59884-18-3, 64858-36-2

rac-trans-4-hydroperoxyifosfamide

Conditions
ConditionsYield
With dihydrogen peroxide; ozone In acetone at 0℃; for 4h;A n/a
B 8%
C 16%
ilfosfamide
3778-73-2

ilfosfamide

(-)-4-ketoifosfamide
84681-42-5

(-)-4-ketoifosfamide

Conditions
ConditionsYield
With dihydrogen peroxide; iron(II) sulfate In water at 0℃; for 1h;5%
ilfosfamide
3778-73-2

ilfosfamide

(S)-(-)-2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
72578-74-6

(S)-(-)-2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran
ilfosfamide
3778-73-2

ilfosfamide

(R)-(+)-2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
72578-73-5

(R)-(+)-2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran
ilfosfamide
3778-73-2

ilfosfamide

Phosphoric acid mono-{3-[(2-amino-ethyl)-(2-hydroxy-ethyl)-amino]-propyl} ester
64724-15-8

Phosphoric acid mono-{3-[(2-amino-ethyl)-(2-hydroxy-ethyl)-amino]-propyl} ester

Conditions
ConditionsYield
In water
ilfosfamide
3778-73-2

ilfosfamide

2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
29102-47-4

2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran
ilfosfamide
3778-73-2

ilfosfamide

ethanol
64-17-5

ethanol

Conditions
ConditionsYield
With potassium hydroxide; aluminum nickel In methanol Product distribution; degradation under various conditions with preparation of nonmutagenic reaction mixtures of products;
ilfosfamide
3778-73-2

ilfosfamide

A

chloroethylamine
689-98-5

chloroethylamine

B

2-hydroxy-2-oxo-3-(2-chloroethyl)-1,3,2-oxazaphosphorine
141056-56-6

2-hydroxy-2-oxo-3-(2-chloroethyl)-1,3,2-oxazaphosphorine

C

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

D

(2-chloro-ethyl)-phosphoramidic acid mono-[3-(2-chloro-ethylamino)-propyl] ester
241482-17-7

(2-chloro-ethyl)-phosphoramidic acid mono-[3-(2-chloro-ethylamino)-propyl] ester

Conditions
ConditionsYield
With sodium phosphate at 20℃; Rate constant; other subst. ifosfamides; var. pH;
ilfosfamide
3778-73-2

ilfosfamide

phosphoric acid mono-(3-aziridin-1-yl-propyl) ester

phosphoric acid mono-(3-aziridin-1-yl-propyl) ester

Conditions
ConditionsYield
With potassium hydroxide; perchloric acid 1.) RT, 24 h, 2.) RT, 24 h; Multistep reaction;
ilfosfamide
3778-73-2

ilfosfamide

A

phosphoric acid mono-(3-aziridin-1-yl-propyl) ester

phosphoric acid mono-(3-aziridin-1-yl-propyl) ester

B

1-propanol, 3-<(2-hydroxyethyl)amino>-, dihydrogen phosphate

1-propanol, 3-<(2-hydroxyethyl)amino>-, dihydrogen phosphate

C

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

Conditions
ConditionsYield
With water at 50℃; for 408h;
ilfosfamide
3778-73-2

ilfosfamide

A

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

phosphoric acid mono-[3-(2-chloro-ethylamino)-propyl] ester

B

(2-chloro-ethyl)-phosphoramidic acid mono-[3-(2-chloro-ethylamino)-propyl] ester
241482-17-7

(2-chloro-ethyl)-phosphoramidic acid mono-[3-(2-chloro-ethylamino)-propyl] ester

Conditions
ConditionsYield
With hydrogenchloride for 0.5h; Ambient temperature;
ilfosfamide
3778-73-2

ilfosfamide

A

2-chloroethanal
107-20-0

2-chloroethanal

B

acrolein
107-02-8

acrolein

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; NADPH; supersomes P450 In phosphate buffer at 37℃; for 0.5h; pH=7.4; Enzyme kinetics; Product distribution;
ilfosfamide
3778-73-2

ilfosfamide

2-hydroxy-2-oxo-3-(2-chloroethyl)-1,3,2-oxazaphosphorine
141056-56-6

2-hydroxy-2-oxo-3-(2-chloroethyl)-1,3,2-oxazaphosphorine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. HCl / 0.5 h / Ambient temperature
2: aq. HCl
View Scheme
ilfosfamide
3778-73-2

ilfosfamide

3-(2-chloroethyl)-N-(2-iodoethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

3-(2-chloroethyl)-N-(2-iodoethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaH / tetrahydrofuran
2: HI / diethyl ether
View Scheme
ilfosfamide
3778-73-2

ilfosfamide

N-(2-acetyloxyethyl)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
110971-91-0

N-(2-acetyloxyethyl)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaH / tetrahydrofuran
2: 43 percent / 1 h / Ambient temperature
View Scheme
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