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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

19-Norandrost-5(10)-ene-3,17-dione Manufacturer/High quality/Best price/In stock

Cas:3962-66-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 19-Norandrost-5(10)-Ene-3,17-Dione supplier in China

Cas:3962-66-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Oestr-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:1

Negotiable

Type:Other

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

19-Nor-5(10)-androstene-3,17-dione

Cas:3962-66-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 3962-66-1 with competitive price

Cas:3962-66-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

hot sell 19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

19-Norandrost-5(10)-ene-3,17-dione/ LIDE PHARMA- Factory supply / Best price

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

19-Norandrost-5(10)-ene-3,17-dione 3962-66-1

Cas:3962-66-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

19-Norandrost-5(10)-ene-3,17-dione CAS:3962-66-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

19-Norandrost-5(10)-ene-3,17-dione CAS:3962-66-1

Cas:3962-66-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Estr-5(10)-ene-3,17-dione 3962-66-1

Cas:3962-66-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

19-NORANDROST-5(10)-ENE-3,17-DIONE 3962-66-1

Cas:3962-66-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Estr-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:100 Gram

Negotiable

Type:Other

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 19-Norandrost-5(10)-Ene-3,17-Dione CAS No.:3962-66-1 Molecule Formula:C18H24O2 Molecule Weight:272.38 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard

High Quality 19-Norandrost-5(10)-Ene-3,17-Dione on stock

Cas:3962-66-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

19-Nor-androst-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Manufacturers

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

19-Norandrost-5(10) -ene-317-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Bromobenzylamine

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

19-Norandrost-5(10) -Ene-317-Dione

Cas:3962-66-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

manufacture Application:The refence standard products, for lab use, also we could produce bigger quantity on yr requirement.

19-norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

19-Norandrost-5(10)-ene-3,17-dione

Cas:3962-66-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

androst-4-ene-3,17-dion-19-oic acid
4757-95-3

androst-4-ene-3,17-dion-19-oic acid

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
With pyridine for 0.5h; Heating;82%
In pyridine at 50℃; for 1h;700 mg
19-oxoandrostenedione
968-49-0

19-oxoandrostenedione

A

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

B

(19S)-3-hydroxy-3β,19-oxido-5β,19-cycloandrostane-17-one

(19S)-3-hydroxy-3β,19-oxido-5β,19-cycloandrostane-17-one

C

(19R)-19-hydroxy-5β,19-cycloandrostane-3,17-dione
160617-57-2

(19R)-19-hydroxy-5β,19-cycloandrostane-3,17-dione

D

(19S)-19-hydroxy-5β,19-cycloandrostane-3,17-dione
160617-58-3

(19S)-19-hydroxy-5β,19-cycloandrostane-3,17-dione

Conditions
ConditionsYield
With acetic acid; zinc for 1.5h; Title compound not separated from byproducts;A 3.3%
B n/a
C 62.5%
D n/a
With acetic acid; zinc for 1.5h;A 3.3%
B n/a
C 62.5%
D n/a
19-oxoandrostenedione
968-49-0

19-oxoandrostenedione

A

17β-hydroxy-estr-5(10)-en-3-one
1089-78-7

17β-hydroxy-estr-5(10)-en-3-one

B

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

C

(19R)-19-hydroxy-5β,19-cycloandrostane-3,17-dione
160617-57-2

(19R)-19-hydroxy-5β,19-cycloandrostane-3,17-dione

D

(19R)-17β,19-dihydroxy-5β,19-cycloandrostan-3-one
192373-63-0

(19R)-17β,19-dihydroxy-5β,19-cycloandrostan-3-one

Conditions
ConditionsYield
With ammonia; lithium In tetrahydrofuran for 0.5h;A 12%
B 11%
C 11%
D 34%
3-methoxyestra-2,5(10)-dien-17-one
17976-32-8

3-methoxyestra-2,5(10)-dien-17-one

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
With methanol; acetic acid
19-hydroxy-4-androstene-3,17-dione
510-64-5

19-hydroxy-4-androstene-3,17-dione

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / pyridinium dichromate / CH2Cl2 / 18 h / 20 °C
2: 3.3 percent / Zn, 50percent aq. AcOH / 1.5 h
View Scheme
Multi-step reaction with 2 steps
1: 7.3 g / Cr2O3, conc. H2SO4 / acetone / 0.5 h / 10 - 15 °C
2: 700 mg / pyridine / 1 h / 50 °C
View Scheme
17,17-ethanediyldioxy-3-methoxy-estra-2,5(10)-diene
1238-30-8

17,17-ethanediyldioxy-3-methoxy-estra-2,5(10)-diene

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
With malonic acid In water; acetone at 20℃; for 4h; Temperature; Reagent/catalyst;
Estrone
53-16-7

Estrone

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 130 °C
2.1: orthoformic acid triethyl ester; boron trifluoride diethyl etherate / 0.25 h / 25 °C
2.2: 5 h / 25 °C
3.1: ammonia; sodium hydroxide; lithium / tetrahydrofuran / 0.5 h / -78 - -50 °C
3.2: 1 h
4.1: malonic acid / acetone; water / 4 h / 20 °C
View Scheme
estrone 3-methyl ether
1624-62-0

estrone 3-methyl ether

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: orthoformic acid triethyl ester; boron trifluoride diethyl etherate / 0.25 h / 25 °C
1.2: 5 h / 25 °C
2.1: ammonia; sodium hydroxide; lithium / tetrahydrofuran / 0.5 h / -78 - -50 °C
2.2: 1 h
3.1: malonic acid / acetone; water / 4 h / 20 °C
View Scheme
17,17-ethylenedioxy-3-methoxyoestra-1,3,5(10)-triene
28336-29-0

17,17-ethylenedioxy-3-methoxyoestra-1,3,5(10)-triene

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: ammonia; sodium hydroxide; lithium / tetrahydrofuran / 0.5 h / -78 - -50 °C
1.2: 1 h
2.1: malonic acid / acetone; water / 4 h / 20 °C
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

10β-hydroxy-19-norandrost-4-ene-3,17-dione
5189-96-8

10β-hydroxy-19-norandrost-4-ene-3,17-dione

Conditions
ConditionsYield
With copper(II) bis(trifluoromethanesulfonate); triphenylphosphine; N,N,N',N'-tetramethylguanidine In tetrahydrofuran at 20℃; for 17h; regioselective reaction;56%
(i) Na2CrO4, AcOH, (ii) SiO2; Multistep reaction;
Perbenzoic acid
93-59-4

Perbenzoic acid

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

10β-hydroxy-19-norandrost-4-ene-3,17-dione
5189-96-8

10β-hydroxy-19-norandrost-4-ene-3,17-dione

Conditions
ConditionsYield
With benzene
methanol
67-56-1

methanol

estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

3,3-dimethoxyestr-5(10)-en-17-one
19257-34-2

3,3-dimethoxyestr-5(10)-en-17-one

Conditions
ConditionsYield
With malonic acid for 19h;5.1 g
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

ethylene glycol
107-21-1

ethylene glycol

A

3,3-(ethylenedioxy)-5(10)-estren-17-one
6193-99-3

3,3-(ethylenedioxy)-5(10)-estren-17-one

B

estr-5(10)-ene-3,17-dione bis(ethylene ketal)
2220-74-8

estr-5(10)-ene-3,17-dione bis(ethylene ketal)

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 2h; Heating;A 586 mg
B 2.55 g
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

ethylene glycol
107-21-1

ethylene glycol

estr-5(10)-ene-3,17-dione bis(ethylene ketal)
2220-74-8

estr-5(10)-ene-3,17-dione bis(ethylene ketal)

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating; Yield given;
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

Dimethyl chlorophosphate
813-77-4

Dimethyl chlorophosphate

Phosphoric acid dimethyl ester (8R,9S,13S,14S)-13-methyl-17-oxo-2,6,7,8,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester
118544-10-8

Phosphoric acid dimethyl ester (8R,9S,13S,14S)-13-methyl-17-oxo-2,6,7,8,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine; n-butyllithium 1.) hexane, THF, -70 deg C, 15 min, to room temp.; 2.) HMPA, 5 min, room temp.; Yield given. Multistep reaction;
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

3β-Hydroxyestr-5(10)-en-17-one
3461-60-7

3β-Hydroxyestr-5(10)-en-17-one

Conditions
ConditionsYield
(enzymatic reduction);
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

A

C18H24O3

C18H24O3

B

3-keto-5,10β-epoxy-nor-19-methyl androstanone
5190-31-8

3-keto-5,10β-epoxy-nor-19-methyl androstanone

Conditions
ConditionsYield
With dioxyphthalic acid In diethyl ether; chloroform for 2h; Title compound not separated from byproducts;
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

estra-4-ene-3,17-dione
734-32-7

estra-4-ene-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.55 g / TsOH / benzene / 2 h / Heating
2: 1.) tBuOK, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, TsOH, 2 h
View Scheme
Multi-step reaction with 2 steps
1: 2.55 g / TsOH / benzene / 2 h / Heating
2: 1.) tBuOK, CHBr3, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, TsOH, 2 h
View Scheme
Multi-step reaction with 5 steps
1: p-TSA / benzene / Heating
2: N-bromosuccinimide, MgO, H2O / dimethylformamide / 2 h / Ambient temperature
3: 71 percent / NaOMe / methanol; tetrahydrofuran / 8 h / 4 °C
4: 71 percent / KHS, 18-crown-6 / ethane-1,2-diol / 2 h / 140 °C
5: 27 percent / p-TSA / acetone / Ambient temperature
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-((tert-Butyldimethylsilyl)oxy)estr-4-en-3-one
139042-19-6

17β-((tert-Butyldimethylsilyl)oxy)estr-4-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) aq. NaOH, BTEAC, CHCl3, 2.) TsOH / 1.) room temperature, 16 h, 2.) acetone, 30 min
View Scheme
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 1.) tBuOK, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, 2 h
View Scheme
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 1.) tBuOK, CHBr3, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, 2 h
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

19(S)-bromo-9α,19-cyclo-10α-androst-4-ene-3,17-dione

19(S)-bromo-9α,19-cyclo-10α-androst-4-ene-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.55 g / TsOH / benzene / 2 h / Heating
2: 1.) tBuOK, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, TsOH, 2 h
View Scheme
Multi-step reaction with 2 steps
1: 2.55 g / TsOH / benzene / 2 h / Heating
2: 1.) tBuOK, CHBr3, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, TsOH, 2 h
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-hydroxy-19,19-dichloro-5α,19-cyclo-10α-androstan-3-one

17β-hydroxy-19,19-dichloro-5α,19-cyclo-10α-androstan-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) aq. NaOH, BTEAC, CHCl3, 2.) TsOH / 1.) room temperature, 16 h, 2.) acetone, 30 min
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

tert-Butyl-((8R,9S,13S,14S,17S)-3,3-dimethoxy-13-methyl-2,3,4,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yloxy)-dimethyl-silane
158388-33-1

tert-Butyl-((8R,9S,13S,14S,17S)-3,3-dimethoxy-13-methyl-2,3,4,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yloxy)-dimethyl-silane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-(tert-butyldimethylsiloxy)-3,3-ethylenedioxyestr-5(10)-ene
158388-29-5

17β-(tert-butyldimethylsiloxy)-3,3-ethylenedioxyestr-5(10)-ene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-(tert-butyldimethylsiloxy)-19,19-dibromo-5,19-cyclo-10α-androstan-3-one

17β-(tert-butyldimethylsiloxy)-19,19-dibromo-5,19-cyclo-10α-androstan-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) CTAB, aq. NaOH, 2.) TsOH / 1.) 48 h, 2.) acetone, 1 h
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-(tert-butyldimethylsiloxy)-19(S)-chloro-5α-hydroxy-9α,19-cyclo-10α-androstan-3-one

17β-(tert-butyldimethylsiloxy)-19(S)-chloro-5α-hydroxy-9α,19-cyclo-10α-androstan-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) aq. NaOH, BTEAC, CHCl3, 2.) TsOH / 1.) room temperature, 16 h, 2.) acetone, 30 min
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-9α,19-cyclo-10α-androst-4-en-3-one

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-9α,19-cyclo-10α-androst-4-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) CTAB, aq. NaOH, 2.) aq. HCl / 1.) 18 h, 2.) acetone, 30 min
View Scheme
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 1.) tBuOK, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, 2 h
View Scheme
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 1.) tBuOK, CHBr3, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, 2 h
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-(tertbutyldimethylsiloxy)-9α-dichloromethylandrost-5(10)-en-3-one

17β-(tertbutyldimethylsiloxy)-9α-dichloromethylandrost-5(10)-en-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) aq. NaOH, BTEAC, CHCl3, 2.) TsOH / 1.) room temperature, 16 h, 2.) acetone, 30 min
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-3,3-dimethoxy-9α,19-cyclo-10α-androst-5(10)-ene

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-3,3-dimethoxy-9α,19-cyclo-10α-androst-5(10)-ene

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 650 mg / CTAB, aq. NaOH / 18 h / Ambient temperature
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

17β-(tert-butyldimethylsiloxy)-19(S)-chloro-5β,6β-dichloromethylene-3,3-ethylenedioxy-9α,19-cyclo-10α-androstane

17β-(tert-butyldimethylsiloxy)-19(S)-chloro-5β,6β-dichloromethylene-3,3-ethylenedioxy-9α,19-cyclo-10α-androstane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 41 mg / various solvent(s) / 3.5 h / 120 - 130 °C
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-3,3-ethylenedioxy-9α,19-cyclo-10α-androstane

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-3,3-ethylenedioxy-9α,19-cyclo-10α-androstane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 586 mg / TsOH / benzene / 2 h / Heating
2: 1.) NaBH4, 2.) imidazole / 1.) MeOH, 1 h, 2.) DMF, 50 deg C, 2 h
3: 1.) aq. NaOH, CTAB, 2.) TsOH / 1.) 18 h, 2.) acetone
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-9α,19-cyclo-10α-androstan-3-one
158388-34-2

19(S)-bromo-17β-(tert-butyldimethylsiloxy)-5β,6β-dibromomethylene-9α,19-cyclo-10α-androstan-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) CTAB, aq. NaOH, 2.) TsOH / 1.) 48 h, 2.) acetone, 1 h
View Scheme
Multi-step reaction with 4 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 1.) CTAB, aq. NaOH, 2.) aq. HCl / 1.) 18 h, 2.) acetone, 30 min
View Scheme
Multi-step reaction with 5 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
3: 1.7 g / imidazole / dimethylformamide / 1 h / 50 °C
4: 650 mg / CTAB, aq. NaOH / 18 h / Ambient temperature
5: 200 mg / aq. HCl / acetone / 0.5 h / Ambient temperature
View Scheme
estra-5(10)-en-3,17-dione
3962-66-1

estra-5(10)-en-3,17-dione

3,3-dimethoxyestr-5(10)-en-17β-ol
56016-36-5

3,3-dimethoxyestr-5(10)-en-17β-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 5.1 g / malonic acid / 19 h
2: 5.2 g / NaBH4 / methanol / 1 h
View Scheme

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