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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methyl 4-Acetamido-5-Chloro-2-Methoxybenzoate supplier in China

Cas:4093-31-6

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Methyl 4-acetamido-5-chloro-2-methoxybenzoate Cas 4093-31-6 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:cool dry place Pack

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl 4-acetamido-5-chloro-o-anisate

Cas:4093-31-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Methyl 4-Acetamido-2-methoxybenzoate 4093-31-6 Producer

Cas:4093-31-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Acetamido-5-chloro-2-methoxybenzoic acid methyl ester

Cas:4093-31-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM-- 4093-31-6--Methyl 4-acetamido-5-chloro-2-methoxybenzoate factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had establ

TIANFUCHEM-- 4093-31-6--Methyl 4-acetamido-5-chloro-2-methoxybenzoate factory price

Cas:4093-31-6

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Benzenemethanol, -alpha-,2,3-trimethyl- (9CI) Basic information Product Name: Benzenemethanol, -alpha-,2,3-trimethyl- (9CI) Synonyms: Benzenemethanol, -alpha

60907-90-6 Methyl 4-acetamido-5-chloro-2-methoxybenzoate Manufacturer

Cas:4093-31-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Valued High Quality CAS 4093-31-6 with fast shipping

Cas:4093-31-6

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Methyl 4-acetamido-5-chloro-2-methoxybenzoate,intermediates for Metoclopramide

Cas:4093-31-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,4-(acetylamino)-5-chloro-2-methoxy-, methyl ester 4093-31-6

Cas:4093-31-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, Methyl 4-acetamido-5-chloro-2-methoxybenzoate CAS:4093-31-6

Cas:4093-31-6

Min.Order:1 Kilogram

FOB Price: $59.4 / 64.3

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Methyl 4-acetamido-5-chloro-2-methoxybenzoate CAS:4093-31-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in h

Methyl 4-acetamido-5-chloro-2-methoxybenzoate CAS:4093-31-6

Cas:4093-31-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoic acid,4-(acetylamino)-5-chloro-2-methoxy-, methyl ester

Cas:4093-31-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2-METHOXY-4-ACETYLAMINO-5-CHLORO METHYL BENZOATE 4093-31-6

Cas:4093-31-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Methyl 4-Acetamido-5-Chloro-2-Methoxybenzoate

Cas:4093-31-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Methyl4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Methyl 4-acetamido-5-chloro-2-methoxybenzoate Basic information Product Name: Methyl 4-acetamido-5-chloro-2-methoxybenzoate Synonyms: 4-(acetylamino)-5-chloro-2-methoxy-benzoicacimethylester;4-ACETYLAMINO-5-CHLORO-2-METHOXY-BENZOIC ACID METHYL ESTER

Methyl 4-acetamido-5-chloro-2-methoxybenzoate 4093-31-6

Cas:4093-31-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: Methyl-2-methoxy-4-acetamido-5-chlorobenzoate CAS No.:4093-31-6 Molecule Formula:C11H12ClNO4 Molecule Weight:257.67 Purity: 98.0% Package: 25kg/drum Description:White to creamy crystalline powder Manufacture Standards:En

Lower Price Methyl-2-methoxy-4-acetamido-5-chlorobenzoate

Cas:4093-31-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Methyl 4-acetamido-5-chloro-2-methoxybenzoate

Cas:4093-31-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

methyl 4-(acetylamino)-o-anisate
4093-29-2

methyl 4-(acetylamino)-o-anisate

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
With N-chloro-succinimide In N,N-dimethyl-formamide at 40 - 65℃; for 9h; Temperature;90.3%
With palladium diacetate; copper diacetate; copper dichloride In dichloromethane at 90℃; for 48h;30%
With sodium hypochlorite for 1h; Yield given;
With N-chloro-succinimide In N,N-dimethyl-formamide
methyl 4-amino-5-chloro-2-methoxybenzoate
20896-27-9

methyl 4-amino-5-chloro-2-methoxybenzoate

acetic anhydride
108-24-7

acetic anhydride

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
With acetic acid at 50℃; for 5h;80%
methyl 4-amino-5-chloro-2-methoxybenzoate
20896-27-9

methyl 4-amino-5-chloro-2-methoxybenzoate

acetic acid
64-19-7

acetic acid

acetyl chloride
75-36-5

acetyl chloride

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
for 12h; Reflux;67%
6-amino-5-nitro-pyridine-2-carboxylic acid methyl ester
538372-32-6

6-amino-5-nitro-pyridine-2-carboxylic acid methyl ester

A

imidazo[4,5-b]pyridine-pyrrole

imidazo[4,5-b]pyridine-pyrrole

B

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
hydrogen In palladium-carbonA n/a
B 63%
Methyl 4-amino-2-methoxybenzoate
27492-84-8

Methyl 4-amino-2-methoxybenzoate

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2O / 1.) room temp., 30 min., 2.) 60-70 deg C, 1 h
2: aq. sodium hypochlorite / 1 h
View Scheme
Multi-step reaction with 2 steps
1: N-chloro-succinimide / acetonitrile / 3 h / Reflux
2: 12 h / Reflux
View Scheme
methyl 4-amino-5-chloro-2-methoxybenzoate
20896-27-9

methyl 4-amino-5-chloro-2-methoxybenzoate

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
With acetic acid In acetic anhydride
methyl 4-acetamido-2-hydroxybenzoate
4093-28-1

methyl 4-acetamido-2-hydroxybenzoate

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / N,N-dimethyl-formamide
2: N-chloro-succinimide / N,N-dimethyl-formamide
View Scheme
4-Aminosalicylic acid
65-49-6

4-Aminosalicylic acid

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sulfuric acid / 2 h / 20 °C
2: acetic acid / 1 h
3: sodium hydroxide / N,N-dimethyl-formamide
4: N-chloro-succinimide / N,N-dimethyl-formamide
View Scheme
methyl 4-aminosalicylate
4136-97-4

methyl 4-aminosalicylate

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid / 1 h
2: sodium hydroxide / N,N-dimethyl-formamide
3: N-chloro-succinimide / N,N-dimethyl-formamide
View Scheme
4-amino-5-chloro-2-methoxybenzoic acid
7206-70-4

4-amino-5-chloro-2-methoxybenzoic acid

methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride / 5 h / 80 °C
2: acetic acid / 5 h / 50 °C
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

methyl 4-acetylamino-5-chloro-2-hydroxybenzoate
24190-77-0

methyl 4-acetylamino-5-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
Stage #1: methyl 2-methoxy 4-acetamido 5-chloro benzoate With boron trichloride In dichloromethane at 0 - 15℃; for 4h;
Stage #2: With water In dichloromethane
95%
Stage #1: methyl 2-methoxy 4-acetamido 5-chloro benzoate With aluminum (III) chloride In 1,2-dichloro-ethane for 8h; Heating / reflux;
Stage #2: With hydrogenchloride; water In dichloromethane; 1,2-dichloro-ethane at 0℃;
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

phenylboronic acid
98-80-6

phenylboronic acid

2-acetamino-4-methoxy-5-methoxycarbonyl-1,1'-biphenyl
1058140-74-1

2-acetamino-4-methoxy-5-methoxycarbonyl-1,1'-biphenyl

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate In tetrahydrofuran; water at 70℃; for 3h; Suzuki-Miyaura cross-coupling;95%
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-acetylamino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester
126463-85-2

4-acetylamino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

Conditions
ConditionsYield
With nitric acid at -35 - -30℃; for 0.166667h;93.8%
With nitric acid at 20℃; for 0.166667h;91%
With sulfuric acid; nitric acid at 0 - 10℃; for 0.5h;85%
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

C11H11(2)HClNO4

C11H11(2)HClNO4

Conditions
ConditionsYield
With [(1,5-cyclooctadiene)Ir(1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene)(PPh3)]PF6; deuterium In dichloromethane at 20℃; for 2h; Sealed tube;92%
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-(acetylamino)-5-chloro-2-methoxybenzoic acid
24201-13-6

4-(acetylamino)-5-chloro-2-methoxybenzoic acid

Conditions
ConditionsYield
88%
With sodium hydroxide In water85%
With sodium hydroxide In methanol at 60℃; for 1h;84%
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-amino-5-chloro-2-methoxybenzoic acid
7206-70-4

4-amino-5-chloro-2-methoxybenzoic acid

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water84%
With potassium hydroxide In ethanol; water Heating / reflux;
Stage #1: methyl 2-methoxy 4-acetamido 5-chloro benzoate With sodium hydroxide In ethanol
Stage #2: With hydrogenchloride In water
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

chloroacetyl chloride
79-04-9

chloroacetyl chloride

C12H11Cl2NO5

C12H11Cl2NO5

Conditions
ConditionsYield
Stage #1: chloroacetyl chloride With aluminum (III) chloride In dichloromethane at 0 - 10℃; for 0.5h;
Stage #2: methyl 2-methoxy 4-acetamido 5-chloro benzoate In dichloromethane at 0 - 10℃; for 4h;
83%
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

methyl iodide
74-88-4

methyl iodide

4-(N-acetyl-N-methylamino)-5-chloro-2-methoxybenzoic acid methyl ester
202822-76-2

4-(N-acetyl-N-methylamino)-5-chloro-2-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 5h; Heating;45%
With NaH In tetrahydrofuran; water; ethyl acetate4.77 g (45%)
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

ethyl iodide
75-03-6

ethyl iodide

4-(N-acetyl-N-ethyl)amino-5-chloro-2-methoxybenzoic acid
483303-91-9

4-(N-acetyl-N-ethyl)amino-5-chloro-2-methoxybenzoic acid

Conditions
ConditionsYield
Stage #1: methyl 2-methoxy 4-acetamido 5-chloro benzoate With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1h;
Stage #2: ethyl iodide In tetrahydrofuran at 20℃;
10 g
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-(N-ethyl-N-methylamino)-5-chloro-2-methoxybenzenemethanol
202822-77-3

4-(N-ethyl-N-methylamino)-5-chloro-2-methoxybenzenemethanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 45 percent / NaH / tetrahydrofuran / 5 h / Heating
2: 89.5 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

3-[5-chloro-4-[(ethylmethylamino)-2-methoxyphenyl]-methyl]-1,3,4-oxadiazol-2-(3H)-one
202822-84-2

3-[5-chloro-4-[(ethylmethylamino)-2-methoxyphenyl]-methyl]-1,3,4-oxadiazol-2-(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 45 percent / NaH / tetrahydrofuran / 5 h / Heating
2: 89.5 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h
3: 60 percent / PPh3; DEAD / tetrahydrofuran / 24 h / 0 °C
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

3-[5-chloro-4-[(ethylmethylamino)-2-hydroxyphenyl]-methyl]-1,3,4-oxadiazol-2-(3H)-one

3-[5-chloro-4-[(ethylmethylamino)-2-hydroxyphenyl]-methyl]-1,3,4-oxadiazol-2-(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 45 percent / NaH / tetrahydrofuran / 5 h / Heating
2: 89.5 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h
3: 60 percent / PPh3; DEAD / tetrahydrofuran / 24 h / 0 °C
4: pyridine hydrochloride / 1 h / Heating
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

3,4-diamino-2-methoxy-benzoic acid methyl ester
538372-37-1

3,4-diamino-2-methoxy-benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 91 percent / HNO3 / 0.17 h / 20 °C
2: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
3: H2; Et3N / Pd/C / 6 h / 3800 Torr
View Scheme
Multi-step reaction with 3 steps
1: nitric acid / 0.33 h / 20 °C
2: sulfuric acid / methanol / Reflux
3: palladium on activated charcoal; triethylamine / methanol / 16 h / 3040.2 Torr / Inert atmosphere
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester
457947-61-4

4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / HNO3 / 0.17 h / 20 °C
2: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: nitric acid; sulfuric acid / 1 h / 0 °C
2: sulfuric acid / methanol / 7 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 0.33 h / 20 °C
2: sulfuric acid / methanol / Reflux
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

2-(4-amino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzoimidazole-5-carboxylic acid methyl ester

2-(4-amino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzoimidazole-5-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 91 percent / HNO3 / 0.17 h / 20 °C
2.1: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
3.1: H2; Et3N / Pd/C / 6 h / 3800 Torr
4.1: HBTU; DIEA / dimethylformamide / 36 h
4.2: 494 mg / AcOH / 7 h / 90 °C
5.1: H2 / Pd/C / dimethylformamide / 5 h / 7600 Torr
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

4-methoxy-2-(1-methyl-4-nitro-1H-pyrrol-2-yl)-3H-benzimidazole-5-carboxylic acid methyl ester
538372-38-2

4-methoxy-2-(1-methyl-4-nitro-1H-pyrrol-2-yl)-3H-benzimidazole-5-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 91 percent / HNO3 / 0.17 h / 20 °C
2.1: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
3.1: H2; Et3N / Pd/C / 6 h / 3800 Torr
4.1: HBTU; DIEA / dimethylformamide / 36 h
4.2: 494 mg / AcOH / 7 h / 90 °C
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzimidazole-5-carboxylic acid methyl ester
538372-39-3

2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzimidazole-5-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 91 percent / HNO3 / 0.17 h / 20 °C
2.1: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
3.1: H2; Et3N / Pd/C / 6 h / 3800 Torr
4.1: HBTU; DIEA / dimethylformamide / 36 h
4.2: 494 mg / AcOH / 7 h / 90 °C
5.1: H2 / Pd/C / dimethylformamide / 5 h / 7600 Torr
6.1: 248 mg / DIEA / dimethylformamide
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzimidazole-5-carboxylic acid
538372-40-6

2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrol-2-yl)-4-methoxy-3H-benzimidazole-5-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 91 percent / HNO3 / 0.17 h / 20 °C
2.1: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
3.1: H2; Et3N / Pd/C / 6 h / 3800 Torr
4.1: HBTU; DIEA / dimethylformamide / 36 h
4.2: 494 mg / AcOH / 7 h / 90 °C
5.1: H2 / Pd/C / dimethylformamide / 5 h / 7600 Torr
6.1: 248 mg / DIEA / dimethylformamide
7.1: 73 percent / aq. NaOH / dioxane / 20 - 50 °C
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

5-chloro-4-ethylamino-2-methoxybenzoic acid
206434-46-0

5-chloro-4-ethylamino-2-methoxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaH / tetrahydrofuran / 1 h / 0 - 20 °C
1.2: 10 g / tetrahydrofuran / 20 °C
2.1: 20 percent aq. NaOH / 15 h / Heating
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

methyl 4-acetylamino-3-amino-5-chloro-2-methoxybenzoate
126463-86-3

methyl 4-acetylamino-3-amino-5-chloro-2-methoxybenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 73 percent / conc. H2SO4; fuming HNO3 / 0.08 h / 10 °C
2: 96 percent / H2 / Raney-Ni / ethanol; H2O / 1 h / 20 °C / 3344 Torr
View Scheme
Multi-step reaction with 2 steps
1: 62 percent / HNO3
2: H2 / Ra-Ni
View Scheme
Multi-step reaction with 2 steps
1: 93.8 percent / HNO3 fuming / 0.17 h / -35 - -30 °C
2: H2 / 10percent Pd/C / methanol; tetrahydrofuran / 4 h / 760 Torr / Ambient temperature
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

methyl 7-chloro-4-methoxy-2-methyl-1H-benzimidazole-5-carboxylate
126463-87-4

methyl 7-chloro-4-methoxy-2-methyl-1H-benzimidazole-5-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 73 percent / conc. H2SO4; fuming HNO3 / 0.08 h / 10 °C
2: 96 percent / H2 / Raney-Ni / ethanol; H2O / 1 h / 20 °C / 3344 Torr
3: 100 percent / p-TsOH*H2O / toluene / 1 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: 93.8 percent / HNO3 fuming / 0.17 h / -35 - -30 °C
2: H2 / 10percent Pd/C / methanol; tetrahydrofuran / 4 h / 760 Torr / Ambient temperature
3: 6N aq. HCl / acetic acid / 2 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid; nitric acid / 0.5 h / 0 - 10 °C
2: hydrogen / nickel / ethanol; water / 5 h / 20 °C / 1551.49 Torr
3: toluene-4-sulfonic acid / toluene / 1 h / Heating / reflux
View Scheme
methyl 2-methoxy 4-acetamido 5-chloro benzoate
4093-31-6

methyl 2-methoxy 4-acetamido 5-chloro benzoate

7-chloro-4-methoxy-1H-benzotriazole-5-carboxylic acid
199931-42-5

7-chloro-4-methoxy-1H-benzotriazole-5-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 73 percent / conc. H2SO4; fuming HNO3 / 0.08 h / 10 °C
2: 96 percent / H2 / Raney-Ni / ethanol; H2O / 1 h / 20 °C / 3344 Torr
3: conc. H2SO4; aq. NaNO2 / 1 h / 5 °C
4: 4.7 g / H2O / 18 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 62 percent / HNO3
2: H2 / Ra-Ni
3: aq. H2SO4, NaNO2 / 0 °C
4: Heating
View Scheme

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