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Hangzhou Maytime Bio-Tech Co.,Ltd.

We are Top supplier for Etodolac with high quality and competitive price. CEP,DMF,EDMF are available. Appearance:white or almost white powder Storage:store in well closed container Package:25kgs/fiber drum Application:Nonsteroidal Antiinflammat

Etodolac

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Etodolac Manufacturer/High quality/Best price/In stock

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Etodolac CAS NO.41340-25-4

Cas:41340-25-4

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Etodolac Cas 41340-25-4 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:1kg/foill ba

Factory supply Etodolac Cas 41340-25-4 with high quality and best price

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hefei TNJ chemical industry co.,ltd

Specifications 1.high purity 2.consistent quality 3.competitive price 4.Fast Shipping Appearance:powder Storage:dry environment Package:25kg/drum or as your needs Application:anti-inflammatory. Transportation:by se

Etodolac 41340-25-4

Cas:41340-25-4

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Etodolac manufacturer with low price

Cas:41340-25-4

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Etodolac

Cas:41340-25-4

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Etodolac 41340-25-4 ISO Producer

Cas:41340-25-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Etodolac

Cas:41340-25-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CAS. 41340-25-4 Etodolac

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 16.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 41340-25-4 with best quality

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material Etodolac CAS NO.41340-25-4

Cas:41340-25-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

USDMF EDMF are all available! Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the re

Etodolac USDMF EDMF

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

EtodolacCAS41340-25-4

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

English name: Etodolac Alias:1,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ACETIC ACI Molecular formula: C17H21NO3 Molecular weight: 287.36 CAS No.: 41340-25-4 Appearance: white powder Storage:Store in cool and dry place, away from sun light. P

Etodolac CAS:41340-25-4

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool & d

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Etodolac 41340-25-4

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Anti-inflammatory, Etodolac CAS:41340-25-4

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $118.9 / 123.6

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Etodolac CAS: 41340-25-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Etodolac CAS: 41340-25-4

Cas:41340-25-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Etodolac

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all em

Etodolac CAS: 41340-25-4

Cas:41340-25-4

Min.Order:1 Gram

FOB Price: $95.0 / 100.0

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Etodolac

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Etodolac

Cas:41340-25-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Price, service, company and transport advantage : 1. best service, high quality and reasonable price 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's customers' r

Beat price/Etodolac

Cas:41340-25-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Etodolac

Cas:41340-25-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Etodolac 41340-25-4

Cas:41340-25-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Etodolac

Cas:41340-25-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Yuanmeng Biological Technology Co., Ltd.

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

Good Quality Etodolac CAS 41340-25-4

Cas:41340-25-4

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Trading Company

inquiry

JINING XINHE CHEMICAL CO., LTD

Advantage 1: The product passed the professional production process and quality inspection, the purity is 99% +. 2: Highly qualified engineers to provide technical documents and service. 3: We could provide sample for your test. 4: High qualit

Etodolac 41340-25-4

Cas:41340-25-4

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Etodolac

Cas:41340-25-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

7-ethyl-2-(1H-indol-3-yl)ethan-1-ol
41340-36-7

7-ethyl-2-(1H-indol-3-yl)ethan-1-ol

ethyl propanoylacetate
4949-44-4

ethyl propanoylacetate

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
(i) TsOH, benzene, (ii) aq. NaOH, EtOH; Multistep reaction;
2,2-Dimethyl-propionic acid 2-(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetoxymethyl ester

2,2-Dimethyl-propionic acid 2-(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetoxymethyl ester

A

2,2-Dimethyl-propionic acid 2-((S)-1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetoxymethyl ester

2,2-Dimethyl-propionic acid 2-((S)-1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetoxymethyl ester

B

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
With Lipase QL In di-isopropyl ether; water for 192h; Product distribution; Ambient temperature; various lipase enzymes;
(R)-etodolac
87226-41-3

(R)-etodolac

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
With tin(IV) chloride In tetrahydrofuran; dichloromethane for 4h; Heating / reflux;
sulfuric acid In isopropyl alcohol at 20℃; for 23h; Product distribution / selectivity;
(R)-etodolac
87226-41-3

(R)-etodolac

(S)-etodolac
87249-11-4

(S)-etodolac

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
With tin(IV) chloride In dichloromethane at 20℃; for 2h;
Stage #1: (R)-etodolac; (S)-etodolac In dichloromethane at 20℃; for 2h;
Stage #2: With sodium hydroxide; formic acid at 0℃; for 1h; pH=5;
(S)-etodolac
87249-11-4

(S)-etodolac

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
sulfuric acid In isopropyl alcohol at 20℃; for 4 - 18h; Product distribution / selectivity;
boron trifluoride diethyl etherate In isopropyl alcohol at 20℃; for 15h; Product distribution / selectivity;
7-ethyl-2-(1H-indol-3-yl)ethan-1-ol
41340-36-7

7-ethyl-2-(1H-indol-3-yl)ethan-1-ol

methyl propanoyl acetate
30414-53-0

methyl propanoyl acetate

etodolac
41340-25-4

etodolac

Conditions
ConditionsYield
With sulfuric acid In methanol Pictet-Spengler Synthesis;
etodolac
41340-25-4

etodolac

(+/-)-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)ethanol
200880-25-7

(+/-)-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)ethanol

Conditions
ConditionsYield
With LiAlH4 In tetrahydrofuran; hexane; ethyl acetate98%
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 12h;92%
N-tert-butoxycarbonyl-3-aminopropanol
58885-58-8

N-tert-butoxycarbonyl-3-aminopropanol

etodolac
41340-25-4

etodolac

Boc-aminopropanol-etodolac

Boc-aminopropanol-etodolac

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 20℃; Cooling with ice;96%
Magnolol
528-43-8

Magnolol

etodolac
41340-25-4

etodolac

5,5'-diallyl-2'-hydroxy-[1,1'-biphenyl]-2-yl-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate

5,5'-diallyl-2'-hydroxy-[1,1'-biphenyl]-2-yl-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 1h;90%
With dmap In dichloromethane at 25 - 30℃;90%
acetic acid
64-19-7

acetic acid

etodolac
41340-25-4

etodolac

2-(dimethylamino)ethyl 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetamide acetate

2-(dimethylamino)ethyl 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetamide acetate

Conditions
ConditionsYield
Stage #1: N,N-dimethylethylenediamine; etodolac With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In acetonitrile at 20℃; for 3h;
Stage #2: acetic acid In ethyl acetate
89.4%
2,2,2,-trichloroethoxycarbonyl azide

2,2,2,-trichloroethoxycarbonyl azide

etodolac
41340-25-4

etodolac

2,2,2-trichloroethyl ((1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)methyl)carbamate

2,2,2-trichloroethyl ((1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)methyl)carbamate

Conditions
ConditionsYield
With dmap; copper diacetate In acetonitrile at 80℃; for 3h; Schlenk technique; Sealed tube;86%
methanol
67-56-1

methanol

etodolac
41340-25-4

etodolac

methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)-indole-1-acetate

methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)-indole-1-acetate

Conditions
ConditionsYield
With sulfuric acid for 8h; Reflux;85%
With sulfuric acid for 3h; Reflux;66%
With sulfuric acid
With sulfuric acid for 3h; Reflux;
3-hydroxypropyl selenocyanate
115423-27-3

3-hydroxypropyl selenocyanate

etodolac
41340-25-4

etodolac

3-selenocyanatopropyl 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate

3-selenocyanatopropyl 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate

Conditions
ConditionsYield
Stage #1: etodolac In N,N-dimethyl-formamide at 25℃; for 0.5h;
Stage #2: 3-hydroxypropyl selenocyanate In N,N-dimethyl-formamide at 25℃; for 16h;
85%
thymol
89-83-8

thymol

etodolac
41340-25-4

etodolac

2-isopropyl-5-methylphenyl 2-(1,8‑diethyl-4,9-dihydro-3Hpyrano[3,4-b]indol-1-yl)acetate

2-isopropyl-5-methylphenyl 2-(1,8‑diethyl-4,9-dihydro-3Hpyrano[3,4-b]indol-1-yl)acetate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 72h; Steglich Esterification;83.5%
etodolac
41340-25-4

etodolac

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetamide
591752-31-7

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetamide

Conditions
ConditionsYield
Stage #1: etodolac With oxalyl dichloride at 20℃;
Stage #2: With ammonium hydroxide
82.5%
curcumin
458-37-7

curcumin

etodolac
41340-25-4

etodolac

((1E,6E)-3,5-dioxohepta-1,6-diene-1,7-diyl)bis(2-methoxy-4,1-phenylene) bis(2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate)

((1E,6E)-3,5-dioxohepta-1,6-diene-1,7-diyl)bis(2-methoxy-4,1-phenylene) bis(2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate)

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 1h;80%
curcumin
458-37-7

curcumin

etodolac
41340-25-4

etodolac

A

C36H35NO8

C36H35NO8

B

C51H50N2O10

C51H50N2O10

Conditions
ConditionsYield
With dmap In dichloromethane at 25 - 30℃;A 56%
B 80%
Magnolol
528-43-8

Magnolol

etodolac
41340-25-4

etodolac

5,5'-diallyl-[1,1'-biphenyl]-2,2'-diyl-bis(2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate)

5,5'-diallyl-[1,1'-biphenyl]-2,2'-diyl-bis(2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate)

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 1h;78%
With dmap In dichloromethane at 25 - 30℃;78%
benzyl bromide
100-39-0

benzyl bromide

etodolac
41340-25-4

etodolac

2-(9-benzyl-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid

2-(9-benzyl-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 50℃; for 2h;73%
1-selenocyano-2-ethylamine hydrobromide

1-selenocyano-2-ethylamine hydrobromide

etodolac
41340-25-4

etodolac

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(2-selenocyanatoethyl)acetamide

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(2-selenocyanatoethyl)acetamide

Conditions
ConditionsYield
Stage #1: etodolac With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at 25℃; for 0.5h;
Stage #2: 1-selenocyano-2-ethylamine hydrobromide In dichloromethane; N,N-dimethyl-formamide at 25℃; for 16h;
72%
2-azido-1-phenylethan-1-one
1816-88-2

2-azido-1-phenylethan-1-one

etodolac
41340-25-4

etodolac

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(2-oxo-2-phenylethyl)acetamide

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(2-oxo-2-phenylethyl)acetamide

Conditions
ConditionsYield
In 1,2-dichloro-ethane at 110℃; for 10h; Sealed tube;72%
2-selenocyanatopropanamine hydrobromide

2-selenocyanatopropanamine hydrobromide

etodolac
41340-25-4

etodolac

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(3-selenocyanatopropyl)acetamide

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)-N-(3-selenocyanatopropyl)acetamide

Conditions
ConditionsYield
Stage #1: etodolac With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at 25℃; for 0.5h; Inert atmosphere;
Stage #2: 2-selenocyanatopropanamine hydrobromide In dichloromethane; N,N-dimethyl-formamide at 25℃; for 16h; Inert atmosphere;
65%
Stage #1: etodolac With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at 25℃; for 0.5h;
Stage #2: 2-selenocyanatopropanamine hydrobromide In dichloromethane; N,N-dimethyl-formamide at 25℃; for 16h;
60%
etodolac
41340-25-4

etodolac

C17H23NO2

C17H23NO2

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; Inert atmosphere;59%
{(1R,2R)-cyclohexane-1,2-diamine}dichloridoplatinum(II)
38780-40-4, 52691-24-4, 61848-70-2, 61848-66-6, 61848-62-2

{(1R,2R)-cyclohexane-1,2-diamine}dichloridoplatinum(II)

etodolac
41340-25-4

etodolac

C23H34ClN3O3Pt

C23H34ClN3O3Pt

Conditions
ConditionsYield
With sodium carbonate; silver nitrate In N,N-dimethyl-formamide at 20℃; for 24h; Darkness;52%
dihydrocapsaicin
19408-84-5

dihydrocapsaicin

etodolac
41340-25-4

etodolac

(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid 2-methoxy-4-[(8-methyl-nonanoylamino)-methyl]-phenyl ester
1224429-03-1

(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid 2-methoxy-4-[(8-methyl-nonanoylamino)-methyl]-phenyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30 - 35℃;49.6%
Propargylamine
2450-71-7

Propargylamine

etodolac
41340-25-4

etodolac

C20H24N2O2

C20H24N2O2

Conditions
ConditionsYield
Stage #1: etodolac With triethylamine In tetrahydrofuran at -50℃; for 1h; Inert atmosphere;
Stage #2: Propargylamine With isobutyl chloroformate In tetrahydrofuran at -50 - 20℃; for 13h; Inert atmosphere;
46.8%
ammonium hydroxide
1336-21-6

ammonium hydroxide

oxalyl dichloride
79-37-8

oxalyl dichloride

etodolac
41340-25-4

etodolac

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetamide
591752-31-7

2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetamide

Conditions
ConditionsYield
N,N-dimethyl-formamide In tetrahydrofuran; hexane; dichloromethane; ethyl acetate35%
potassium ethyl methylmalonate
103362-70-5

potassium ethyl methylmalonate

etodolac
41340-25-4

etodolac

C19H23NO4

C19H23NO4

Conditions
ConditionsYield
Stage #1: etodolac With 1,1'-carbonyldiimidazole Inert atmosphere;
Stage #2: potassium ethyl methylmalonate With magnesium chloride Inert atmosphere;
35%
capsaicin
404-86-4

capsaicin

etodolac
41340-25-4

etodolac

(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid 2-methoxy-4-[(8-methyl-non-6-enoylamino)-methyl]-phenyl ester
1224429-01-9

(1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid 2-methoxy-4-[(8-methyl-non-6-enoylamino)-methyl]-phenyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30 - 35℃;30.2%
etodolac
41340-25-4

etodolac

A

1,8-diethyl-4-oxo-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetic acid
111478-86-5

1,8-diethyl-4-oxo-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetic acid

B

1,8-diethyl-4-hydroxy-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetic acid

1,8-diethyl-4-hydroxy-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetic acid

Conditions
ConditionsYield
With iodosylbenzene; Cl8TTPFe(III)Cl In dichloromethane at 20℃; for 2h;A 20%
B 25%
etodolac
41340-25-4

etodolac

methyl iodide
74-88-4

methyl iodide

A

3a,10-diethyl-5,6,6a,11-tetrahydro-6a-methylfuro<3',2'2,3>pyrano<3,4-b>indol-2(3H)-one
114737-77-8

3a,10-diethyl-5,6,6a,11-tetrahydro-6a-methylfuro<3',2'2,3>pyrano<3,4-b>indol-2(3H)-one

B

2-(1,8-diethyl-9-methyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)acetic acid
114720-05-7

2-(1,8-diethyl-9-methyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)acetic acid

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 50℃; for 2h;A 20%
B 16%
etodolac
41340-25-4

etodolac

7-ethyl-2-(1-methylenepropyl)-1H-indole-3-ethanol

7-ethyl-2-(1-methylenepropyl)-1H-indole-3-ethanol

Conditions
ConditionsYield
In methanol for 72h; Heating; pH 6.0;20%
(OC-6-33)-(diammine)dichloridodihydroxidoplatinum(IV)
125074-46-6, 31246-62-5, 31246-63-6, 31246-66-9, 53261-25-9

(OC-6-33)-(diammine)dichloridodihydroxidoplatinum(IV)

etodolac
41340-25-4

etodolac

C34H46Cl2N4O6Pt

C34H46Cl2N4O6Pt

Conditions
ConditionsYield
With triethylamine; O‐(1H‐benzotriazol‐1‐yl)‐N,N,N′,N′‐tetramethyluronium tetrafluoroborate In N,N-dimethyl-formamide at 20℃; for 24h; Darkness;19.5%
etodolac
41340-25-4

etodolac

A

7-ethyl-2-(1H-indol-3-yl)ethan-1-ol
41340-36-7

7-ethyl-2-(1H-indol-3-yl)ethan-1-ol

B

7-ethyl-2-(1-methyl-1-propenyl)-1H-indole-3-ethanol

7-ethyl-2-(1-methyl-1-propenyl)-1H-indole-3-ethanol

C

7-ethyl-2-(1-methylenepropyl)-1H-indole-3-ethanol

7-ethyl-2-(1-methylenepropyl)-1H-indole-3-ethanol

D

1,8-diethyl-1-methyl-1,3,4,9-tetrahydropyrano-<3,4-b>indole

1,8-diethyl-1-methyl-1,3,4,9-tetrahydropyrano-<3,4-b>indole

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 85℃; for 18h; Product distribution; Rate constant; Thermodynamic data; Ea, ΔS<*>, mechanism of etodolac degradation in aqueous solutionsat various temperatures (75-905 deg C), time and pH, effect of pH and temperature, catalytic effect of buffer system;
etodolac
41340-25-4

etodolac

(+)-etodolac
87249-11-4

(+)-etodolac

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